Page last updated: 2024-10-30

lamotrigine and Cognitive Decline

lamotrigine has been researched along with Cognitive Decline in 4 studies

Research Excerpts

ExcerptRelevanceReference
"We conducted a double-blind crossover study of a low dose (15 mg, 'placebo') and an active dose (195 mg) of methylene blue in patients with bipolar disorder treated with lamotrigine."9.24Methylene blue treatment for residual symptoms of bipolar disorder: randomised crossover study. ( Alda, M; Blagdon, R; Dursun, S; Garnham, J; Hajek, T; MacLellan, S; MacQueen, G; McKinnon, M; Nair, C; O'Donovan, C, 2017)
"Lamotrigine (LTG) is a broad-spectrum antiepileptic drug that is widely used in clinic."5.46Effect of lamotrigine on epilepsy-induced cognitive impairment and hippocampal neuronal apoptosis in pentylenetetrazole-kindled animal model. ( Dong, RF; Tian, S; Wang, WP; Zhang, B; Zhang, C; Zhang, JW, 2017)
"We conducted a double-blind crossover study of a low dose (15 mg, 'placebo') and an active dose (195 mg) of methylene blue in patients with bipolar disorder treated with lamotrigine."5.24Methylene blue treatment for residual symptoms of bipolar disorder: randomised crossover study. ( Alda, M; Blagdon, R; Dursun, S; Garnham, J; Hajek, T; MacLellan, S; MacQueen, G; McKinnon, M; Nair, C; O'Donovan, C, 2017)
"Lamotrigine (LTG) is a broad-spectrum antiepileptic drug that is widely used in clinic."1.46Effect of lamotrigine on epilepsy-induced cognitive impairment and hippocampal neuronal apoptosis in pentylenetetrazole-kindled animal model. ( Dong, RF; Tian, S; Wang, WP; Zhang, B; Zhang, C; Zhang, JW, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Zhuo, C1
Zhou, C1
Tian, H1
Li, Q1
Chen, J1
Yang, L1
Zhang, Q1
Li, R1
Ma, X1
Cai, Z1
Chen, G1
Xu, Y1
Song, X1
Huber-Mollema, Y1
van Iterson, L1
Oort, FJ1
Lindhout, D1
Rodenburg, R1
Alda, M1
McKinnon, M1
Blagdon, R1
Garnham, J1
MacLellan, S1
O'Donovan, C1
Hajek, T1
Nair, C1
Dursun, S1
MacQueen, G1
Zhang, B1
Zhang, JW1
Wang, WP1
Dong, RF1
Tian, S1
Zhang, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-Blind Trial of Methylene Blue for Cognitive Dysfunction in Bipolar Disorder[NCT00214877]Phase 340 participants (Anticipated)Interventional2003-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lamotrigine and Cognitive Decline

ArticleYear
Methylene blue treatment for residual symptoms of bipolar disorder: randomised crossover study.
    The British journal of psychiatry : the journal of mental science, 2017, Volume: 210, Issue:1

    Topics: Adult; Anxiety; Bipolar Disorder; Cognitive Dysfunction; Cross-Over Studies; Depression; Double-Blin

2017

Other Studies

3 other studies available for lamotrigine and Cognitive Decline

ArticleYear
Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder.
    Translational psychiatry, 2022, 09-02, Volume: 12, Issue:1

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cognitive Dysfu

2022
Neurocognition after prenatal levetiracetam, lamotrigine, carbamazepine or valproate exposure.
    Journal of neurology, 2020, Volume: 267, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Cognitive Dysfunction; Female; Humans; Lam

2020
Effect of lamotrigine on epilepsy-induced cognitive impairment and hippocampal neuronal apoptosis in pentylenetetrazole-kindled animal model.
    Synapse (New York, N.Y.), 2017, Volume: 71, Issue:2

    Topics: Animals; Anticonvulsants; Apoptosis; CA1 Region, Hippocampal; Cognitive Dysfunction; Epilepsy; Femal

2017