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lamotrigine and Cocaine Abuse

lamotrigine has been researched along with Cocaine Abuse in 12 studies

Research Excerpts

ExcerptRelevanceReference
"Lamotrigine treatment was well tolerated in this sample and associated with statistically significant improvement in mood and drug cravings but not drug use."6.71Lamotrigine in patients with bipolar disorder and cocaine dependence. ( Bobadilla, L; Brown, ES; Nejtek, VA; Orsulak, PJ; Perantie, DC, 2003)
"Lamotrigine treatment was associated with significant improvements in mood, drug craving, and drug use."5.33Lamotrigine for bipolar disorder and comorbid cocaine dependence: a replication and extension study. ( Beard, L; Brown, ES; Dhanani, N; Orsulak, P; Perantie, DC; Rush, AJ, 2006)
"Data were analyzed from two completed studies: an open-label trial of lamotrigine in patients with bipolar disorder (BPD) and cocaine-related disorder, and a placebo-controlled trial of quetiapine in patients with BPD and alcohol-related disorders."3.75Attrition factors in clinical trials of comorbid bipolar and substance-related disorders. ( Brown, ES; Nomamiukor, N, 2009)
" As part of a large study on the use of lamotrigine in patients with bipolar disorder and cocaine dependence, the frequency and nature of drug dreams, triggers for dreams, and response to the dreams during study participation were assessed in 37 outpatients for as long as 36 weeks."3.72Drug dreams in outpatients with bipolar disorder and cocaine dependence. ( Brown, ES; Dhanani, N; Perantie, DC; Yee, T, 2004)
"Lamotrigine treatment was well tolerated in this sample and associated with statistically significant improvement in mood and drug cravings but not drug use."2.71Lamotrigine in patients with bipolar disorder and cocaine dependence. ( Bobadilla, L; Brown, ES; Nejtek, VA; Orsulak, PJ; Perantie, DC, 2003)
"Lamotrigine pretreatment altered neither the physiological responses nor the subjective ratings of cocaine's pleasurable or aversive mood effects."2.69Effects of lamotrigine on behavioral and cardiovascular responses to cocaine in human subjects. ( Hameedi, FA; Jatlow, PI; Kosten, TR; McCance-Katz, EF; Pearsall, HR; Rosen, MI; Saleem, R; Winther, LC; Woods, SW, 2000)
"Cocaine dependence is a public health problem characterised by recidivism and a host of medical and psychosocial complications."2.53Antipsychotic medications for cocaine dependence. ( Amato, L; Indave, BI; Minozzi, S; Pani, PP, 2016)
"Lamotrigine treatment was associated with significant improvements in mood, drug craving, and drug use."1.33Lamotrigine for bipolar disorder and comorbid cocaine dependence: a replication and extension study. ( Beard, L; Brown, ES; Dhanani, N; Orsulak, P; Perantie, DC; Rush, AJ, 2006)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's6 (50.00)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fagan, CS1
Carmody, TJ2
McClintock, SM1
Suris, A1
Nakamura, A1
Jeon-Slaughter, H1
Lo, A1
Brown, ES6
Indave, BI1
Minozzi, S1
Pani, PP1
Amato, L1
Nomamiukor, N1
Pavlovic, Z1
Sunderajan, P1
Hu, LT1
Sowell, SM1
Nejtek, VA1
Perantie, DC3
Orsulak, PJ1
Bobadilla, L1
Yee, T1
Dhanani, N2
Berger, SP1
Winhusen, TM1
Somoza, EC1
Harrer, JM1
Mezinskis, JP1
Leiderman, DB1
Montgomery, MA1
Goldsmith, RJ1
Bloch, DA1
Singal, BM1
Elkashef, A1
Beard, L1
Orsulak, P1
Rush, AJ1
Margolin, A1
Avants, SK1
DePhilippis, D1
Kosten, TR2
Rosenbaum, JF1
Fredman, SJ1
Winther, LC1
Saleem, R1
McCance-Katz, EF1
Rosen, MI1
Hameedi, FA1
Pearsall, HR1
Jatlow, PI1
Woods, SW1

Reviews

1 review available for lamotrigine and Cocaine Abuse

ArticleYear
Antipsychotic medications for cocaine dependence.
    The Cochrane database of systematic reviews, 2016, Mar-19, Volume: 3

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cocaine-Related Disorders; Haloperidol; Humans;

2016

Trials

4 trials available for lamotrigine and Cocaine Abuse

ArticleYear
A randomized, double-blind, placebo-controlled, trial of lamotrigine therapy in bipolar disorder, depressed or mixed phase and cocaine dependence.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Calcium Channel Blockers; Cocaine-Related Disorders; Depr

2012
Lamotrigine in patients with bipolar disorder and cocaine dependence.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:2

    Topics: Adult; Anticonvulsants; Behavior, Addictive; Bipolar Disorder; Cocaine-Related Disorders; Drug Thera

2003
A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence.
    Addiction (Abingdon, England), 2005, Volume: 100 Suppl 1

    Topics: Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cocaine-Related Disorders; Cyclohexanecarboxyl

2005
Effects of lamotrigine on behavioral and cardiovascular responses to cocaine in human subjects.
    The American journal of drug and alcohol abuse, 2000, Volume: 26, Issue:1

    Topics: Administration, Oral; Adult; Affect; Arousal; Blood Pressure; Cocaine-Related Disorders; Dose-Respon

2000

Other Studies

7 other studies available for lamotrigine and Cocaine Abuse

ArticleYear
The effect of cognitive functioning on treatment attendance and adherence in comorbid bipolar disorder and cocaine dependence.
    Journal of substance abuse treatment, 2015, Volume: 49

    Topics: Adult; Bipolar Disorder; Cocaine-Related Disorders; Cognition Disorders; Diagnosis, Dual (Psychiatry

2015
Attrition factors in clinical trials of comorbid bipolar and substance-related disorders.
    Journal of affective disorders, 2009, Volume: 112, Issue:1-3

    Topics: Adult; Alcohol-Related Disorders; Amphetamine-Related Disorders; Anticonvulsants; Antipsychotic Agen

2009
Lamotrigine reduces craving and depressive symptoms in cocaine dependence.
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Winter, Volume: 23, Issue:1

    Topics: Behavior, Addictive; Cocaine-Related Disorders; Depression; Humans; Lamotrigine; Triazines

2011
Drug dreams in outpatients with bipolar disorder and cocaine dependence.
    The Journal of nervous and mental disease, 2004, Volume: 192, Issue:3

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Antimanic Agents; Bipolar Disorder; Cocaine-Related Disord

2004
Lamotrigine for bipolar disorder and comorbid cocaine dependence: a replication and extension study.
    Journal of affective disorders, 2006, Volume: 93, Issue:1-3

    Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Brief Psychiatric Rating Scale; Cocaine;

2006
A preliminary investigation of lamotrigine for cocaine abuse in HIV-seropositive patients.
    The American journal of drug and alcohol abuse, 1998, Volume: 24, Issue:1

    Topics: Adult; Buprenorphine; Cocaine-Related Disorders; Combined Modality Therapy; Dose-Response Relationsh

1998
Pramipexole treatment for cocaine cravings.
    The American journal of psychiatry, 1999, Volume: 156, Issue:11

    Topics: Adult; Antidepressive Agents; Behavior, Addictive; Benzothiazoles; Bipolar Disorder; Cocaine-Related

1999