Page last updated: 2024-10-30

lamotrigine and Cardiac Arrest, Sudden

lamotrigine has been researched along with Cardiac Arrest, Sudden in 6 studies

Research Excerpts

ExcerptRelevanceReference
"Lamotrigine (LTG) has recently been shown to inhibit the cardiac rapid delayed rectifier potassium ion current (Ikr)."5.34Lamotrigine in idiopathic epilepsy - increased risk of cardiac death? ( Aurlien, D; Gjerstad, L; Taubøll, E, 2007)
"There is insufficient evidence to support or refute that lamotrigine is associated with sudden death or ECG changes in people with or without epilepsy as compared to antiseizure medication or placebo, due to the high risk of bias in most studies and low precision and inconsistency in the reported results."5.22Sudden Death and Cardiac Arrythmia With Lamotrigine: A Rapid Systematic Review. ( Bunschoten, JW; Devinsky, O; French, JA; Husein, N; Keezer, MR; Sander, JW; Thijs, RD, 2022)
"Cardiac arrhythmia has been suggested as a cause of death in some patients with SUDEP."1.72Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death. ( Bagnall, RD; Berkovic, SF; Reid, CA; Scheffer, IE; Semsarian, C; Soh, MS, 2022)
"Lamotrigine (LTG) has recently been shown to inhibit the cardiac rapid delayed rectifier potassium ion current (Ikr)."1.34Lamotrigine in idiopathic epilepsy - increased risk of cardiac death? ( Aurlien, D; Gjerstad, L; Taubøll, E, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Bunschoten, JW1
Husein, N1
Devinsky, O1
French, JA1
Sander, JW1
Thijs, RD1
Keezer, MR1
Soh, MS1
Bagnall, RD1
Semsarian, C1
Scheffer, IE1
Berkovic, SF1
Reid, CA1
Aurlien, D3
Leren, TP1
Taubøll, E3
Gjerstad, L3
VanLandingham, KE1
Dixon, RM1

Reviews

1 review available for lamotrigine and Cardiac Arrest, Sudden

ArticleYear
Sudden Death and Cardiac Arrythmia With Lamotrigine: A Rapid Systematic Review.
    Neurology, 2022, 04-26, Volume: 98, Issue:17

    Topics: Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Epilepsy; Humans; Lamotrigine; Risk F

2022

Other Studies

5 other studies available for lamotrigine and Cardiac Arrest, Sudden

ArticleYear
Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death.
    Epilepsia, 2022, Volume: 63, Issue:6

    Topics: Anticonvulsants; Arrhythmias, Cardiac; Cause of Death; Death, Sudden; Death, Sudden, Cardiac; Epilep

2022
New SCN5A mutation in a SUDEP victim with idiopathic epilepsy.
    Seizure, 2009, Volume: 18, Issue:2

    Topics: Adolescent; Anticonvulsants; Base Sequence; Death, Sudden, Cardiac; Epilepsy; Female; Humans; Lamotr

2009
Lamotrigine in idiopathic epilepsy - increased risk of cardiac death?
    Acta neurologica Scandinavica, 2007, Volume: 115, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Death, Sudden, Cardiac; Epilepsy; Female; Humans; Lamotrigine; T

2007
Lamotrigine in idiopathic epilepsy - increased risk of cardiac death.
    Acta neurologica Scandinavica, 2007, Volume: 116, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Response Rela

2007
An insufficient effect of lamotrigine leading to fatal seizures.
    Acta neurologica Scandinavica, 2008, Volume: 117, Issue:4

    Topics: Acidosis; Age Factors; Anticonvulsants; Apnea; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Re

2008