lamotrigine has been researched along with Borderline Personality Disorder in 20 studies
Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors examined whether lamotrigine is a clinically effective and cost-effective treatment for people with borderline personality disorder." | 9.27 | The Clinical Effectiveness and Cost-Effectiveness of Lamotrigine in Borderline Personality Disorder: A Randomized Placebo-Controlled Trial. ( Barrett, B; Crawford, MJ; Cunningham, G; Dale, O; Ganguli, P; Lawrence-Smith, G; Leeson, V; Lemonsky, F; Lykomitrou, G; Montgomery, AA; Morriss, R; Munjiza, J; Paton, C; Reilly, JG; Sanatinia, R; Singh, V; Skorodzien, I; Tan, W; Tyrer, P, 2018) |
| "The objective of this study was to evaluate the effectiveness of lamotrigine in reducing affective instability in borderline personality disorder (BPD)." | 9.14 | A preliminary study of lamotrigine in the treatment of affective instability in borderline personality disorder. ( Bieri, KA; Reich, DB; Zanarini, MC, 2009) |
| " The goal of this study was to compare the efficacy of lamotrigine versus placebo in the treatment of aggression in women meeting the criteria for borderline personality disorder (BPD)." | 9.11 | Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study. ( Lahmann, C; Leiberich, PK; Loew, TH; Nickel, C; Nickel, MK; Rother, WK; Tritt, K, 2005) |
| "To assess the use of lamotrigine to treat symptoms of affective instability in patients with borderline personality disorder." | 7.74 | Retrospective case review of lamotrigine use for affective instability of borderline personality disorder. ( Jamison, KL; Weinstein, W, 2007) |
| " We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287-291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks." | 7.74 | Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up. ( Leiberich, P; Nickel, MK; Pedrosa Gil, F; Tritt, K, 2008) |
| "Recent reports suggesting lamotrigine as an effective treatment in bipolar disorder, and perhaps borderline personality disorder, a common comorbid personality disorder in bipolar patients, led us to retrospectively examine patients from two bipolar studies to investigate this pattern of comorbidity, and to determine whether lamotrigine effected the dimensions of borderline personality." | 7.72 | Borderline personality disorder in patients with bipolar disorder and response to lamotrigine. ( Hedges, DW; Marchant, BK; Preston, GA; Reimherr, FW; Strong, RE, 2004) |
| "People with borderline personality disorder (BPD) experience rapid and distressing changes in mood, poor social functioning and have high rates of suicidal behaviour." | 6.80 | Lamotrigine versus inert placebo in the treatment of borderline personality disorder: study protocol for a randomized controlled trial and economic evaluation. ( Barrett, B; Byford, S; Crawford, MJ; Cunningham, G; Gakhal, K; Lawrence-Smith, G; Leeson, V; Lemonsky, F; Lykomitrou, G; Montgomery, A; Morriss, R; Paton, C; Reilly, JG; Sanatinia, R; Tan, W; Tyrer, P, 2015) |
| "The authors examined whether lamotrigine is a clinically effective and cost-effective treatment for people with borderline personality disorder." | 5.27 | The Clinical Effectiveness and Cost-Effectiveness of Lamotrigine in Borderline Personality Disorder: A Randomized Placebo-Controlled Trial. ( Barrett, B; Crawford, MJ; Cunningham, G; Dale, O; Ganguli, P; Lawrence-Smith, G; Leeson, V; Lemonsky, F; Lykomitrou, G; Montgomery, AA; Morriss, R; Munjiza, J; Paton, C; Reilly, JG; Sanatinia, R; Singh, V; Skorodzien, I; Tan, W; Tyrer, P, 2018) |
| "The objective of this study was to evaluate the effectiveness of lamotrigine in reducing affective instability in borderline personality disorder (BPD)." | 5.14 | A preliminary study of lamotrigine in the treatment of affective instability in borderline personality disorder. ( Bieri, KA; Reich, DB; Zanarini, MC, 2009) |
| " The goal of this study was to compare the efficacy of lamotrigine versus placebo in the treatment of aggression in women meeting the criteria for borderline personality disorder (BPD)." | 5.11 | Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study. ( Lahmann, C; Leiberich, PK; Loew, TH; Nickel, C; Nickel, MK; Rother, WK; Tritt, K, 2005) |
| " The anticonvulsants valproate and topiramate appeared to have the most empirical support for having a favorable effect on symptoms of borderline personality disorder." | 4.85 | [Empirical evidence for the use of anticonvulsants in personality disorders]. ( Emrich, HM; Sieberer, M, 2009) |
| "To assess the use of lamotrigine to treat symptoms of affective instability in patients with borderline personality disorder." | 3.74 | Retrospective case review of lamotrigine use for affective instability of borderline personality disorder. ( Jamison, KL; Weinstein, W, 2007) |
| " We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287-291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks." | 3.74 | Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up. ( Leiberich, P; Nickel, MK; Pedrosa Gil, F; Tritt, K, 2008) |
| "Recent reports suggesting lamotrigine as an effective treatment in bipolar disorder, and perhaps borderline personality disorder, a common comorbid personality disorder in bipolar patients, led us to retrospectively examine patients from two bipolar studies to investigate this pattern of comorbidity, and to determine whether lamotrigine effected the dimensions of borderline personality." | 3.72 | Borderline personality disorder in patients with bipolar disorder and response to lamotrigine. ( Hedges, DW; Marchant, BK; Preston, GA; Reimherr, FW; Strong, RE, 2004) |
| "People with borderline personality disorder (BPD) experience rapid and distressing changes in mood, poor social functioning and have high rates of suicidal behaviour." | 2.80 | Lamotrigine versus inert placebo in the treatment of borderline personality disorder: study protocol for a randomized controlled trial and economic evaluation. ( Barrett, B; Byford, S; Crawford, MJ; Cunningham, G; Gakhal, K; Lawrence-Smith, G; Leeson, V; Lemonsky, F; Lykomitrou, G; Montgomery, A; Morriss, R; Paton, C; Reilly, JG; Sanatinia, R; Tan, W; Tyrer, P, 2015) |
| "Patients with borderline personality disorder also appeared to benefit." | 2.48 | Lamotrigine in the treatment of unipolar depression with and without comorbidities: a literature review. ( Ali, R; Zavodnick, AD, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reilly, EE | 1 |
| Berner, LA | 1 |
| Trunko, ME | 1 |
| Schwartz, T | 1 |
| Anderson, LK | 1 |
| Krueger, A | 1 |
| Yu, X | 1 |
| Chen, JY | 1 |
| Cusack, A | 1 |
| Nakamura, T | 1 |
| Kaye, WH | 1 |
| Stoffers-Winterling, J | 1 |
| Storebø, OJ | 1 |
| Lieb, K | 1 |
| Crawford, MJ | 4 |
| Sanatinia, R | 5 |
| Barrett, B | 3 |
| Cunningham, G | 3 |
| Dale, O | 2 |
| Ganguli, P | 2 |
| Lawrence-Smith, G | 3 |
| Leeson, V | 2 |
| Lemonsky, F | 3 |
| Lykomitrou, G | 2 |
| Montgomery, AA | 1 |
| Morriss, R | 3 |
| Munjiza, J | 2 |
| Paton, C | 3 |
| Skorodzien, I | 2 |
| Singh, V | 2 |
| Tan, W | 4 |
| Tyrer, P | 3 |
| Reilly, JG | 3 |
| Leeson, VC | 1 |
| Lykomitrou-Matthews, G | 1 |
| Montgomery, A | 2 |
| Gunderson, JG | 1 |
| Choi-Kain, LW | 1 |
| Smith, EG | 1 |
| Afzal, S | 1 |
| MacLaren, T | 1 |
| McNulty, A | 1 |
| Adele, C | 1 |
| Morah, A | 1 |
| Crawford, M | 1 |
| Byford, S | 1 |
| Gakhal, K | 1 |
| Sieberer, M | 1 |
| Emrich, HM | 1 |
| Gescher, DM | 1 |
| Malevani, J | 1 |
| Reich, DB | 1 |
| Zanarini, MC | 1 |
| Bieri, KA | 1 |
| Zavodnick, AD | 1 |
| Ali, R | 1 |
| Rizvi, ST | 1 |
| Preston, GA | 1 |
| Marchant, BK | 1 |
| Reimherr, FW | 1 |
| Strong, RE | 1 |
| Hedges, DW | 1 |
| Tritt, K | 2 |
| Nickel, C | 1 |
| Lahmann, C | 1 |
| Leiberich, PK | 1 |
| Rother, WK | 1 |
| Loew, TH | 1 |
| Nickel, MK | 2 |
| Weinstein, W | 1 |
| Jamison, KL | 1 |
| Pavlovic, ZM | 1 |
| Leiberich, P | 1 |
| Pedrosa Gil, F | 1 |
| Pinto, OC | 1 |
| Akiskal, HS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Lamotrigine Treatment of Affective Instability in Borderline Personality Disorder[NCT00634062] | Phase 4 | 28 participants (Actual) | Interventional | 2004-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for lamotrigine and Borderline Personality Disorder
| Article | Year |
|---|---|
Pharmacotherapy for Borderline Personality Disorder: an Update of Published, Unpublished and Ongoing Studies.
Topics: Borderline Personality Disorder; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Selecti | 2020 |
[Empirical evidence for the use of anticonvulsants in personality disorders].
Topics: Amines; Anticonvulsants; Borderline Personality Disorder; Carbamazepine; Cyclohexanecarboxylic Acids | 2009 |
[Mood stabilizer in the psychopharmacotherapy of borderline personality disorder].
Topics: Anticonvulsants; Antimanic Agents; Borderline Personality Disorder; Carbamazepine; Female; Fructose; | 2009 |
Lamotrigine in the treatment of unipolar depression with and without comorbidities: a literature review.
Topics: Antimanic Agents; Anxiety Disorders; Borderline Personality Disorder; Comorbidity; Depressive Disord | 2012 |
7 trials available for lamotrigine and Borderline Personality Disorder
| Article | Year |
|---|---|
The Clinical Effectiveness and Cost-Effectiveness of Lamotrigine in Borderline Personality Disorder: A Randomized Placebo-Controlled Trial.
Topics: Adult; Antipsychotic Agents; Borderline Personality Disorder; Cost-Benefit Analysis; Double-Blind Me | 2018 |
Lamotrigine for people with borderline personality disorder: a RCT.
Topics: Adult; Antipsychotic Agents; Borderline Personality Disorder; Cost-Benefit Analysis; Depression; Dou | 2018 |
Improved mental health among LABILE study participants: A qualitative exploration.
Topics: Adult; Antipsychotic Agents; Borderline Personality Disorder; Female; Follow-Up Studies; Humans; Lam | 2019 |
Lamotrigine versus inert placebo in the treatment of borderline personality disorder: study protocol for a randomized controlled trial and economic evaluation.
Topics: Affect; Antipsychotic Agents; Borderline Personality Disorder; Clinical Protocols; Cost-Benefit Anal | 2015 |
A preliminary study of lamotrigine in the treatment of affective instability in borderline personality disorder.
Topics: Adult; Antimanic Agents; Borderline Personality Disorder; Double-Blind Method; Female; Humans; Lamot | 2009 |
Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Aggression; Anger; Antimanic Agents; Borderline Personality Disorder; Double-Blind Method; Fe | 2005 |
Lamotrigine as a promising approach to borderline personality: an open case series without concurrent DSM-IV major mood disorder.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Borderline Pe | 1998 |
9 other studies available for lamotrigine and Borderline Personality Disorder
| Article | Year |
|---|---|
Evaluating the use of lamotrigine to reduce mood lability and impulsive behaviors in adults with chronic and severe eating disorders.
Topics: Adult; Affective Symptoms; Borderline Personality Disorder; Feeding and Eating Disorders; Female; Hu | 2022 |
Medication Management for Patients With Borderline Personality Disorder.
Topics: Anticonvulsants; Borderline Personality Disorder; Cost-Benefit Analysis; Humans; Lamotrigine; Treatm | 2018 |
No Effect of Lamotrigine in Subgroups of Patients With Borderline Personality Disorder: Response to Smith.
Topics: Anticonvulsants; Borderline Personality Disorder; Cost-Benefit Analysis; Humans; Lamotrigine; Treatm | 2018 |
An Opportunity to Report Closer-to-Efficacy Findings in a Study of Lamotrigine for Borderline Personality Disorder.
Topics: Anticonvulsants; Borderline Personality Disorder; Cost-Benefit Analysis; Humans; Lamotrigine; Treatm | 2018 |
Lamotrigine and borderline personality disorder.
Topics: Adolescent; Antimanic Agents; Borderline Personality Disorder; Female; Humans; Lamotrigine; Psychiat | 2002 |
Borderline personality disorder in patients with bipolar disorder and response to lamotrigine.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Borderline Personality Disorder; Comorbidity; Female | 2004 |
Retrospective case review of lamotrigine use for affective instability of borderline personality disorder.
Topics: Adult; Affect; Antimanic Agents; Borderline Personality Disorder; Female; Humans; Lamotrigine; Male; | 2007 |
Lamotrigine for the treatment of impulsive aggression and affective symptoms in a patient with borderline personality disorder comorbid with body dysmorphic disorder.
Topics: Adult; Affective Symptoms; Aggression; Anticonvulsants; Borderline Personality Disorder; Cognition D | 2008 |
Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up.
Topics: Adult; Aggression; Antimanic Agents; Borderline Personality Disorder; Data Interpretation, Statistic | 2008 |