Page last updated: 2024-10-30

lamotrigine and Atrophy

lamotrigine has been researched along with Atrophy in 6 studies

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Falling due to startle-induced seizures (SISs) often leads to injury."5.37Lamotrigine is favourable for startle-induced seizures. ( Fujiwara, T; Ikeda, H; Imai, K; Inoue, Y; Shigematsu, H; Shishido, T; Takahashi, Y; Takayama, R, 2011)
"Lamotrigine trial in SPMS was a randomised control trial to assess whether partial blockade of sodium channels has a neuroprotective effect."1.39Biomarker report from the phase II lamotrigine trial in secondary progressive MS - neurofilament as a surrogate of disease progression. ( Brenner, R; Furby, J; Giovannoni, G; Gnanapavan, S; Grant, D; Hayton, T; Kapoor, R; Leoni, V; Marta, M; Miller, DH; Morant, S; Palace, J; Teunissen, CE, 2013)
"Falling due to startle-induced seizures (SISs) often leads to injury."1.37Lamotrigine is favourable for startle-induced seizures. ( Fujiwara, T; Ikeda, H; Imai, K; Inoue, Y; Shigematsu, H; Shishido, T; Takahashi, Y; Takayama, R, 2011)
"With lamotrigine treatment, the patient who had not had surgery had complete cessation of monthly episodes of status epilepticus and a dramatic reduction of generalized tonic-clonic seizures, and the other patient who received lamotrigine had a 50% reduction of her atonic seizures."1.30Treatment of seizures in subcortical laminar heterotopia with corpus callosotomy and lamotrigine. ( Ko, TS; Lee, JK; Vossler, DG, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gnanapavan, S1
Grant, D1
Morant, S1
Furby, J1
Hayton, T1
Teunissen, CE1
Leoni, V1
Marta, M1
Brenner, R1
Palace, J1
Miller, DH1
Kapoor, R1
Giovannoni, G1
Planche, V1
Chassin, O1
Leduc, L1
Regnier, W1
Kelly, A1
Colamarino, R1
Ikeda, H2
Imai, K1
Shigematsu, H1
Shishido, T1
Takayama, R1
Fujiwara, T1
Takahashi, Y1
Inoue, Y1
Shen, YC1
Brown, ES1
Wolfshohl, J1
Shad, MU1
Vazquez, M1
Osuji, IJ1
Vossler, DG1
Lee, JK1
Ko, TS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
OxCarbazepine as a Neuroprotective Agent in MS: A Phase 2a Trial[NCT02104661]Phase 230 participants (Actual)Interventional2014-10-31Completed
Oxygenation and Perfusion in Patients With Acute Migraine Attacks[NCT03536936]1,000 participants (Actual)Observational2010-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lamotrigine and Atrophy

ArticleYear
Attenuation of the effects of corticosteroids on declarative memory with lamotrigine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Atrophy; Double-Blind Method; Drug Synergi

2008

Other Studies

5 other studies available for lamotrigine and Atrophy

ArticleYear
Biomarker report from the phase II lamotrigine trial in secondary progressive MS - neurofilament as a surrogate of disease progression.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Atrophy; Biomarkers; Brain; Clinical Trials, Phase II as Topic; Disease Progression; Female; Humans;

2013
Sturge-Weber syndrome with late onset hemiplegic migraine-like attacks and progressive unilateral cerebral atrophy.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:1

    Topics: Adult; Anticonvulsants; Atrophy; Cerebral Cortex; Female; Humans; Lamotrigine; Migraine with Aura; S

2014
Lamotrigine is favourable for startle-induced seizures.
    Epileptic disorders : international epilepsy journal with videotape, 2011, Volume: 13, Issue:3

    Topics: Activities of Daily Living; Age of Onset; Anticonvulsants; Atrophy; Brain; Child; Drug Eruptions; El

2011
Lamotrigine in motor and mood symptoms of Huntington's disease.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2008, Volume: 9, Issue:2

    Topics: Antimanic Agents; Atrophy; Caudate Nucleus; Cerebral Cortex; Chorea; Female; Humans; Huntington Dise

2008
Treatment of seizures in subcortical laminar heterotopia with corpus callosotomy and lamotrigine.
    Journal of child neurology, 1999, Volume: 14, Issue:5

    Topics: Adult; Anticonvulsants; Atrophy; Brain Diseases; Cerebellum; Child; Choristoma; Corpus Callosum; Ele

1999