lamotrigine has been researched along with Arrhythmia in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results do not support a significant difference in the reporting risk for cardiac arrest, syncope, tachyarrhythmia, and bradyarrhythmia with lamotrigine in the epileptic indication." | 8.31 | Investigation of cardiac arrhythmia events in patients treated with lamotrigine: FDA adverse event reporing system analysis. ( Aboukaoud, M; Maor, E; Wilf-Yarkoni, A, 2023) |
| "There is insufficient evidence to support or refute that lamotrigine is associated with sudden death or ECG changes in people with or without epilepsy as compared to antiseizure medication or placebo, due to the high risk of bias in most studies and low precision and inconsistency in the reported results." | 5.22 | Sudden Death and Cardiac Arrythmia With Lamotrigine: A Rapid Systematic Review. ( Bunschoten, JW; Devinsky, O; French, JA; Husein, N; Keezer, MR; Sander, JW; Thijs, RD, 2022) |
| "Our results do not support a significant difference in the reporting risk for cardiac arrest, syncope, tachyarrhythmia, and bradyarrhythmia with lamotrigine in the epileptic indication." | 4.31 | Investigation of cardiac arrhythmia events in patients treated with lamotrigine: FDA adverse event reporing system analysis. ( Aboukaoud, M; Maor, E; Wilf-Yarkoni, A, 2023) |
| "The Food and Drug Administration (FDA) is advising health care practitioners that lamotrigine (Lamictal), used in managing seizures and bipolar disorder, may increase the risk of serious and potentially lethal arrythmias." | 4.02 | Lamotrigine may Increase Risk of Arrythmias. ( Aschenbrenner, DS, 2021) |
| "The lamotrigine level was 78." | 2.52 | Evolving Electrocardiographic Changes in Lamotrigine Overdose: A Case Report and Literature Review. ( Casso Dominguez, A; Chavez, P; Herzog, E, 2015) |
| "Cardiac arrhythmia has been suggested as a cause of death in some patients with SUDEP." | 1.72 | Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death. ( Bagnall, RD; Berkovic, SF; Reid, CA; Scheffer, IE; Semsarian, C; Soh, MS, 2022) |
| "Lamotrigine is a phenyltriazine compound that inhibits voltage-gated sodium channels, decreasing release of glutamate and aspartate, and inhibits serotonin, norepinephrine and dopamine reuptake." | 1.39 | A case series of patients with lamotrigine toxicity at one center from 2003 to 2012. ( Burkhart, KK; Donovan, JW; Haggerty, D; Moore, PW, 2013) |
| " During the study, LTG was added to a stable dosage of one to three first line antiepileptic drugs (AED)." | 1.29 | [Cardiac side effects and ECG changes with lamotrigine?--A clinical study]. ( Polatschek, B; Steinhoff, BJ; Stodieck, SR; Tiecks, FP; Wedel, R, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Aschenbrenner, DS | 1 |
| Bunschoten, JW | 1 |
| Husein, N | 1 |
| Devinsky, O | 1 |
| French, JA | 1 |
| Sander, JW | 1 |
| Thijs, RD | 1 |
| Keezer, MR | 1 |
| Soh, MS | 1 |
| Bagnall, RD | 1 |
| Semsarian, C | 1 |
| Scheffer, IE | 1 |
| Berkovic, SF | 1 |
| Reid, CA | 1 |
| Orts, L | 1 |
| Flumian, C | 1 |
| Montastruc, F | 1 |
| Aboukaoud, M | 1 |
| Wilf-Yarkoni, A | 1 |
| Maor, E | 1 |
| Farkas, AN | 1 |
| Marcott, M | 1 |
| Yanta, JH | 1 |
| Pizon, AF | 1 |
| Moore, PW | 1 |
| Donovan, JW | 1 |
| Burkhart, KK | 1 |
| Haggerty, D | 1 |
| Chavez, P | 1 |
| Casso Dominguez, A | 1 |
| Herzog, E | 1 |
| Dawson, EA | 1 |
| Gupta, PK | 1 |
| Madden, CJ | 1 |
| Pacheco, J | 1 |
| Olson, DM | 1 |
| Svalheim, S | 1 |
| Aurlien, D | 2 |
| Amlie, JP | 1 |
| Gjerstad, L | 2 |
| Taubøll, E | 2 |
| VanLandingham, KE | 1 |
| Dixon, RM | 1 |
| Steinhoff, BJ | 1 |
| Stodieck, SR | 1 |
| Tiecks, FP | 1 |
| Wedel, R | 1 |
| Polatschek, B | 1 |
2 reviews available for lamotrigine and Arrhythmia
| Article | Year |
|---|---|
Sudden Death and Cardiac Arrythmia With Lamotrigine: A Rapid Systematic Review.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Epilepsy; Humans; Lamotrigine; Risk F | 2022 |
Evolving Electrocardiographic Changes in Lamotrigine Overdose: A Case Report and Literature Review.
Topics: Adult; Antimanic Agents; Arrhythmias, Cardiac; Bipolar Disorder; Drug Overdose; Electrocardiography; | 2015 |
11 other studies available for lamotrigine and Arrhythmia
| Article | Year |
|---|---|
Lamotrigine may Increase Risk of Arrythmias.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Bipolar Disorder; Epilepsy; Humans; Lamotrigine; Treatment Ou | 2021 |
Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Cause of Death; Death, Sudden; Death, Sudden, Cardiac; Epilep | 2022 |
Lamotrigine and risk of arrhythmias: A global pharmacovigilance analysis.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Humans; Lamotrigine; Pharmacovigilance; Triazines | 2023 |
Investigation of cardiac arrhythmia events in patients treated with lamotrigine: FDA adverse event reporing system analysis.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Bradycardia; Epilepsy; Female; Heart Arrest; Humans; Lamotrig | 2023 |
Bicarbonate refractory QRS prolongation and left bundle-branch block following escitalopram and lamotrigine overdose: A case report and literature review of toxic left bundle-branch block.
Topics: Adult; Arrhythmias, Cardiac; Bicarbonates; Bundle-Branch Block; Citalopram; Electrocardiography; Fem | 2018 |
A case series of patients with lamotrigine toxicity at one center from 2003 to 2012.
Topics: Adrenergic Uptake Inhibitors; Adult; Arrhythmias, Cardiac; Child, Preschool; Dopamine Uptake Inhibit | 2013 |
Arrhythmias in the epilepsy monitoring unit: watching for sudden unexpected death in epilepsy.
Topics: Adolescent; Arrhythmias, Cardiac; Athletic Injuries; Brain Concussion; Cause of Death; Death, Sudden | 2015 |
Signal-averaged and standard electrocardiography in patients with newly diagnosed epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Arrhythmias, Cardiac; Carbamazepine; Electrocardiography; Epilep | 2012 |
Lamotrigine in idiopathic epilepsy - increased risk of cardiac death.
Topics: Adolescent; Adult; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Response Rela | 2007 |
An insufficient effect of lamotrigine leading to fatal seizures.
Topics: Acidosis; Age Factors; Anticonvulsants; Apnea; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Re | 2008 |
[Cardiac side effects and ECG changes with lamotrigine?--A clinical study].
Topics: Adolescent; Adult; Anticonvulsants; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Therapy | 1994 |