Page last updated: 2024-10-30

lamotrigine and Aggression

lamotrigine has been researched along with Aggression in 10 studies

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
" The goal of this study was to compare the efficacy of lamotrigine versus placebo in the treatment of aggression in women meeting the criteria for borderline personality disorder (BPD)."9.11Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study. ( Lahmann, C; Leiberich, PK; Loew, TH; Nickel, C; Nickel, MK; Rother, WK; Tritt, K, 2005)
"To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine."8.81Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002)
" We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287-291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks."7.74Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up. ( Leiberich, P; Nickel, MK; Pedrosa Gil, F; Tritt, K, 2008)
"Lamotrigine (LTG) is a valuable addition to the medical management of epilepsy with wide spectrum of efficacy and good outcomes for quality of life."7.70Aggressive behaviour in intellectually challenged patients with epilepsy treated with lamotrigine. ( Beran, RG; Gibson, RJ, 1998)
" The goal of this study was to compare the efficacy of lamotrigine versus placebo in the treatment of aggression in women meeting the criteria for borderline personality disorder (BPD)."5.11Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study. ( Lahmann, C; Leiberich, PK; Loew, TH; Nickel, C; Nickel, MK; Rother, WK; Tritt, K, 2005)
"To review and summarize the currently available data on the use of anticonvulsant mood stabilizers (carbamazepine, valproic acid, gabapentin, lamotrigine, topiramate) in the treatment of behavioral and psychological symptoms of dementia (BPSD); to determine whether these medications can be recommended for routine clinical use."4.84Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review. ( Konovalov, S; Muralee, S; Tampi, RR, 2008)
"To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine."4.81Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002)
" We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287-291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks."3.74Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up. ( Leiberich, P; Nickel, MK; Pedrosa Gil, F; Tritt, K, 2008)
" However, there is a paucity of literature investigating the use of lamotrigine to treat aggression and agitation in patients with TBI."3.72Beneficial behavioural effects of lamotrigine in traumatic brain injury. ( Friesen, S; Gray, S; Pachet, A; Winkelaar, D, 2003)
"Lamotrigine (LTG) is a valuable addition to the medical management of epilepsy with wide spectrum of efficacy and good outcomes for quality of life."3.70Aggressive behaviour in intellectually challenged patients with epilepsy treated with lamotrigine. ( Beran, RG; Gibson, RJ, 1998)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's8 (80.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kato, H1
Fukatsu, N1
Noguchi, T1
Oshima, T1
Tadokoro, Y1
Kanemoto, K1
Pachet, A1
Friesen, S1
Winkelaar, D1
Gray, S1
Tritt, K2
Nickel, C1
Lahmann, C1
Leiberich, PK1
Rother, WK1
Loew, TH1
Nickel, MK2
Konovalov, S1
Muralee, S1
Tampi, RR1
Pavlovic, ZM2
Leiberich, P1
Pedrosa Gil, F1
Beran, RG1
Gibson, RJ1
Devarajan, S1
Dursun, SM1
Hurley, SC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Lamotrigine Treatment of Affective Instability in Borderline Personality Disorder[NCT00634062]Phase 428 participants (Actual)Interventional2004-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for lamotrigine and Aggression

ArticleYear
Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.
    International psychogeriatrics, 2008, Volume: 20, Issue:2

    Topics: Aggression; Amines; Anticonvulsants; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids

2008
Lamotrigine update and its use in mood disorders.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5

    Topics: Acetates; Aggression; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids;

2002

Trials

1 trial available for lamotrigine and Aggression

ArticleYear
Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:3

    Topics: Adult; Aggression; Anger; Antimanic Agents; Borderline Personality Disorder; Double-Blind Method; Fe

2005

Other Studies

7 other studies available for lamotrigine and Aggression

ArticleYear
Lamotrigine improves aggression in patients with temporal lobe epilepsy.
    Epilepsy & behavior : E&B, 2011, Volume: 21, Issue:2

    Topics: Adult; Aggression; Anticonvulsants; Depression; Epilepsy, Temporal Lobe; Female; Humans; Lamotrigine

2011
Beneficial behavioural effects of lamotrigine in traumatic brain injury.
    Brain injury, 2003, Volume: 17, Issue:8

    Topics: Accidents, Traffic; Adult; Aggression; Anticonvulsants; Brain Injuries; Humans; Lamotrigine; Male; P

2003
Augmentation of clozapine's antiagressive properties with lamotrigine in a patient with chronic disorganized schizophrenia.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:1

    Topics: Adult; Aggression; Anticonvulsants; Antipsychotic Agents; Chronic Disease; Clozapine; Drug Resistanc

2008
Lamotrigine for the treatment of impulsive aggression and affective symptoms in a patient with borderline personality disorder comorbid with body dysmorphic disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 2008,Winter, Volume: 20, Issue:1

    Topics: Adult; Affective Symptoms; Aggression; Anticonvulsants; Borderline Personality Disorder; Cognition D

2008
Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up.
    Journal of psychopharmacology (Oxford, England), 2008, Volume: 22, Issue:7

    Topics: Adult; Aggression; Antimanic Agents; Borderline Personality Disorder; Data Interpretation, Statistic

2008
Aggressive behaviour in intellectually challenged patients with epilepsy treated with lamotrigine.
    Epilepsia, 1998, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Aggression; Anticonvulsants; Comorbidity; Drug Administration Schedule; Epilepsy;

1998
Aggression in dementia with lamotrigine treatment.
    The American journal of psychiatry, 2000, Volume: 157, Issue:7

    Topics: Aged; Aggression; Anticonvulsants; Dementia; Drug Administration Schedule; Female; Frontal Lobe; Hum

2000