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lamotrigine and Adolescent Myoclonic Epilepsy

lamotrigine has been researched along with Adolescent Myoclonic Epilepsy in 23 studies

Research Excerpts

ExcerptRelevanceReference
" Plasma homocysteine, folate, vitamins B12 and B6 (pyridoxal phosphate), and red cell folate levels were measured in samples while she was receiving folic acid therapy for 1 month during the second trimester of pregnancy."3.73Antiepileptic drugs: a case report in a pregnancy with a neural tube defect. ( Bongain, A; Candito, M; Guéant, JL; Naimi, M; Van Obberghen, E, 2006)
"Myoclonic jerks are frequently the debut symptom, while tonic-clonic seizures appear later on."2.48[Juvenile myoclonic epilepsy]. ( Markhus, R; Nakken, KO; Selmer, KK; Syvertsen, MR, 2012)
"Juvenile myoclonic epilepsy is a common idiopathic generalized epileptic syndrome that includes generalized myoclonic seizures and commonly generalized tonic-clonic and generalized absence seizures."2.45The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent? ( Abou-Khalil, B; Montouris, G, 2009)
"Drug treatment of juvenile myoclonic epilepsy (JME) is mainly based on clinical experience and prospective and retrospective studies, with little evidence from randomized clinical trials."2.44Treatment of juvenile myoclonic epilepsy. ( Auvin, S, 2008)
"This study aimed to evaluate antiseizure medication (ASM) use in patients with JME."1.72Trends in the choice of antiseizure medications in juvenile myoclonic epilepsy: A retrospective multi-center study from Turkey between 2010 and 2020. ( Aydın, K; Cansu, A; Esenülkü, G; Haspolat, Ş; İnce, T; Kılıç, B; Okuyaz, Ç; Polat, BG; Serdaroğlu, A; Serdaroğlu, E; Tekgül, H; Topçu, Y, 2022)
"Under lamotrigine, seizure aggravation was observed in 15 patients (two patients during levetiracetam, one patient during zonisamide, none during phenobarbital and valproic acid)."1.62Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy. ( Beier, CP; Gesche, J; Hjalgrim, H; Rubboli, G, 2021)
"Patients with juvenile myoclonic epilepsy (JME) may have uncontrolled seizures."1.51Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy. ( Baftiu, A; Enger, U; Fløgstad, I; Johannessen Landmark, C; Johannessen, SI; Koht, J; Syvertsen, M, 2019)
"Juvenile myoclonic epilepsy is often regarded as a benign epileptic syndrome, but in this setting, half of the individuals with JME have refractory epilepsy with only about a quarter of those seizure-free in the previous year."1.48Juvenile myoclonic epilepsy refractory to treatment in a tertiary referral center. ( Cação, G; Mannan, S; Parra, J; Sander, JW; Sisodiya, SM, 2018)
"JME patients without generalized tonic clonic seizures (GTCS) responded better to LTG (P = 0."1.37Outcome of lamotrigine treatment in juvenile myoclonic epilepsy. ( Ben-Zeev, B; Blatt, I; Bodenstein-Sachar, H; Chapman, J; Gandelman-Marton, R, 2011)
"When lamotrigine was restarted 2 weeks later she developed similar but more severe symptoms which resolved on stopping lamotrigine."1.35Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis. ( Bazaz, R; Lily, O; Maniyar, F; Rooney, C, 2009)
"Lamotrigine is an anti-epileptic drug considered as a first-line therapy in idiopathic generalised epilepsy."1.33[Exacerbation of tonicoclonic seizures in a juvenile myoclonic epileptic taking lamotrigine]. ( Guillon, B; Maiga, Y; Nogues, B, 2006)
"We studied 14 patients with juvenile myoclonic epilepsy (JME), 19 patients with refractory localization-related epilepsy (RLE) and 20 healthy volunteers who were matched for age and sex."1.32Uptake of GABA and activity of GABA-transaminase in platelets from epileptic patients. ( Keränen, T; Peltola, J; Rainesalo, S; Saransaari, P, 2003)
"Most cases of toxic epidermal necrolysis are drug induced."1.32Suspected lamotrigine-induced toxic epidermal necrolysis. ( Demiralay, E; Kilinç, M; Söğüt, A; Söğüt, AG; Uzar, H; Yilmaz, A, 2003)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (52.17)29.6817
2010's8 (34.78)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Kılıç, B1
Serdaroğlu, E1
Polat, BG1
İnce, T1
Esenülkü, G1
Topçu, Y1
Serdaroğlu, A1
Haspolat, Ş1
Tekgül, H1
Okuyaz, Ç1
Cansu, A1
Aydın, K1
Gesche, J1
Hjalgrim, H1
Rubboli, G1
Beier, CP1
Milano, C1
Turco, F1
Pizzanelli, C1
Bonanni, E1
Siciliano, G1
Fornai, F1
Giorgi, FS1
Cação, G1
Parra, J1
Mannan, S1
Sisodiya, SM1
Sander, JW1
Johannessen Landmark, C2
Fløgstad, I2
Baftiu, A2
Syvertsen, M2
Enger, U2
Koht, J2
Johannessen, SI2
Papadavid, E1
Evangelia, P1
Panayiotides, I1
Ioannis, P1
Makris, M1
Michael, M1
Giatrakou, S1
Sophia, G1
Dalamaga, M1
Maria, D1
Stavrianeas, N2
Rigopoulos, D1
Dimitrios, R1
Machado, RA1
García, VF1
Astencio, AG1
Cuartas, VB1
Chowdhury, A1
Brodie, MJ1
Auvin, S1
Maniyar, F1
Rooney, C1
Lily, O1
Bazaz, R1
Montouris, G1
Abou-Khalil, B1
Bodenstein-Sachar, H1
Gandelman-Marton, R1
Ben-Zeev, B1
Chapman, J1
Blatt, I1
Syvertsen, MR1
Markhus, R1
Selmer, KK1
Nakken, KO1
Rainesalo, S1
Saransaari, P1
Peltola, J1
Keränen, T1
Söğüt, A1
Yilmaz, A1
Kilinç, M1
Söğüt, AG1
Demiralay, E1
Uzar, H1
Morris, GL1
Hammer, AE1
Kustra, RP1
Messenheimer, JA1
Candito, M1
Guéant, JL1
Naimi, M1
Bongain, A1
Van Obberghen, E1
Maiga, Y1
Nogues, B1
Guillon, B1
Plattner, B1
Pahs, G1
Kindler, J1
Williams, RP1
Hall, RE1
Mayer, H1
Steiner, H1
Feucht, M1
Alfradique, I1
Vasconcelos, MM1
Biraben, A1
Allain, H1
Scarabin, JM1
Schück, S1
Edan, G1
Carrazana, EJ1
Wheeler, SD1

Reviews

4 reviews available for lamotrigine and Adolescent Myoclonic Epilepsy

ArticleYear
Treatment of juvenile myoclonic epilepsy.
    CNS neuroscience & therapeutics, 2008,Fall, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Lamotrigine; Le

2008
The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?
    Epilepsia, 2009, Volume: 50 Suppl 8

    Topics: Anticonvulsants; Congenital Abnormalities; Delayed-Action Preparations; Drug Design; Epilepsy, Gener

2009
[Juvenile myoclonic epilepsy].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Aug-07, Volume: 132, Issue:14

    Topics: Adolescent; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Female; Humans; Lamotr

2012
Juvenile myoclonic epilepsy.
    Arquivos de neuro-psiquiatria, 2007, Volume: 65, Issue:4B

    Topics: Adolescent; Adult; Anticonvulsants; Child; Diagnosis, Differential; Electroencephalography; Humans;

2007

Trials

2 trials available for lamotrigine and Adolescent Myoclonic Epilepsy

ArticleYear
Efficacy and tolerability of lamotrigine in juvenile myoclonic epilepsy in adults: a prospective, unblinded randomized controlled trial.
    Seizure, 2013, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Female; Humans; Lamotrigine; Male; Middle Aged; Myoclonic Epilep

2013
Lamotrigine for patients with juvenile myoclonic epilepsy following prior treatment with valproate: results of an open-label study.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Drug Evaluation; Humans; Lamotrigine; Myoclonic Epilepsy, Juveni

2004

Other Studies

17 other studies available for lamotrigine and Adolescent Myoclonic Epilepsy

ArticleYear
Trends in the choice of antiseizure medications in juvenile myoclonic epilepsy: A retrospective multi-center study from Turkey between 2010 and 2020.
    Seizure, 2022, Volume: 99

    Topics: Adolescent; Anticonvulsants; Child; Female; Humans; Lamotrigine; Levetiracetam; Male; Myoclonic Epil

2022
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy.
    Epilepsy research, 2021, Volume: 170

    Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Humans; Lamotrigine; Levetiracetam; Myoclonic Epileps

2021
Response to levetiracetam or lamotrigine in subjects with Juvenile Myoclonic Epilepsy previously treated with valproic acid: A single center retrospective study.
    Epilepsy & behavior : E&B, 2021, Volume: 115

    Topics: Anticonvulsants; Female; Humans; Lamotrigine; Levetiracetam; Myoclonic Epilepsy, Juvenile; Retrospec

2021
Juvenile myoclonic epilepsy refractory to treatment in a tertiary referral center.
    Epilepsy & behavior : E&B, 2018, Volume: 82

    Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Resistant Epilepsy; Electroencephalography; Female;

2018
Long-term follow-up with therapeutic drug monitoring of antiepileptic drugs in patients with juvenile myoclonic epilepsy.
    Epilepsy research, 2019, Volume: 155

    Topics: Adolescent; Adult; Anticonvulsants; Drug Monitoring; Female; Follow-Up Studies; Humans; Lamotrigine;

2019
Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy.
    Epilepsy & behavior : E&B, 2019, Volume: 98, Issue:Pt A

    Topics: Adolescent; Adult; Anticonvulsants; Cohort Studies; Female; Humans; Lamotrigine; Levetiracetam; Male

2019
Pityriasis rosea-like eruption associated with lamotrigine.
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:6

    Topics: Adult; Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Lamotrigine; Myocloni

2013
Pharmacological outcomes in juvenile myoclonic epilepsy: Support for sodium valproate.
    Epilepsy research, 2016, Volume: 119

    Topics: Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Drug Resistant Epilepsy; Female; Follow-Up S

2016
Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis.
    Journal of neurology, 2009, Volume: 256, Issue:7

    Topics: Anti-Bacterial Agents; Anticonvulsants; Drug Administration Schedule; Drug-Related Side Effects and

2009
Outcome of lamotrigine treatment in juvenile myoclonic epilepsy.
    Acta neurologica Scandinavica, 2011, Volume: 124, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Female; Humans; Lamotrigine; Male; Myoclonic Epilepsy, Juvenile;

2011
Uptake of GABA and activity of GABA-transaminase in platelets from epileptic patients.
    Epilepsy research, 2003, Volume: 53, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Blood Platelets; Case-Control Studies; Dose-Re

2003
Suspected lamotrigine-induced toxic epidermal necrolysis.
    Acta neurologica Belgica, 2003, Volume: 103, Issue:2

    Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Lamotrigine; Myoclonic Epilepsy,

2003
Antiepileptic drugs: a case report in a pregnancy with a neural tube defect.
    Pediatric neurology, 2006, Volume: 34, Issue:4

    Topics: Adult; Anticonvulsants; Female; Folic Acid; Homocysteine; Humans; Lamotrigine; Myoclonic Epilepsy, J

2006
[Exacerbation of tonicoclonic seizures in a juvenile myoclonic epileptic taking lamotrigine].
    Revue neurologique, 2006, Volume: 162, Issue:11

    Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; M

2006
Juvenile myoclonic epilepsy: a benign disorder? Personality traits and psychiatric symptoms.
    Epilepsy & behavior : E&B, 2007, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Child; Ethosuximide; Female; Fructose; Humans; Lamotrigine; Leve

2007
Exacerbation of juvenile myoclonic epilepsy with lamotrigine.
    Neurology, 2000, Dec-12, Volume: 55, Issue:11

    Topics: Adolescent; Adult; Anticonvulsants; Female; Humans; Lamotrigine; Male; Myoclonic Epilepsy, Juvenile;

2000
Exacerbation of juvenile myoclonic epilepsy with lamotrigine.
    Neurology, 2001, May-22, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Female; Humans; Lamotrigine; Male; Middle Aged; Myoclonic Epilep

2001