lamotrigine has been researched along with Acute Liver Injury, Drug-Induced in 25 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although lamotrigine may be useful for treating patients with treatment-resistant bipolar disorder, some lamotrigine-associated adverse effects, including mild to moderate skin rash, may prevent the continuation of treatment." | 7.88 | Lamotrigine Rechallenge in Treatment-Resistant Bipolar Disorder. ( Inaba, T; Kato, TA; Kunitake, Y; Mizoguchi, Y; Monji, A; Sogawa, R; Tateishi, H, 2018) |
| " We describe a case of AHS with fulminant hepatitis that occurred two weeks after introduction of lamotrigine in a 40-year-old female patient with a recently diagnosed bipolar disorder, no pre-existent systemic organ involvement, and no other medication." | 4.85 | Fulminant hepatitis induced by lamotrigine. ( Marleau, D; Ouellet, G; Tremblay, L, 2009) |
| " More specifically, vigabatrin, which is a very useful and well tolerated new antiepileptic drug for refractory partial epilepsy, should be started at a low dosage of 0." | 4.79 | The new anticonvulsant drugs. Implications for avoidance of adverse effects. ( Krämer, G; Schmidt, D, 1994) |
| "Although lamotrigine may be useful for treating patients with treatment-resistant bipolar disorder, some lamotrigine-associated adverse effects, including mild to moderate skin rash, may prevent the continuation of treatment." | 3.88 | Lamotrigine Rechallenge in Treatment-Resistant Bipolar Disorder. ( Inaba, T; Kato, TA; Kunitake, Y; Mizoguchi, Y; Monji, A; Sogawa, R; Tateishi, H, 2018) |
| "A 43-year-old woman was being treated with oxcarbazepine for depression and was started on lamotrigine 2 weeks prior to her presentation." | 3.74 | Lamotrigine-associated reversible severe hepatitis: a case report. ( Olson, KR; Su-Yin, AN; Tai, WW, 2008) |
| "6 million adverse event reports made to the FDA Adverse Event Reporting System (FAERS) database between July 1, 2018 and March 31, 2020 for DILI due to ASMs commonly used in clinical practice." | 1.62 | Drug-induced liver injury associated with antiseizure medications from the FDA Adverse Event Reporting System (FAERS). ( Catalano, C; Gupta, K; Kamitaki, BK; Minacapelli, CD; Rustgi, V; Wachuku, C; Zhang, P, 2021) |
| "Lamotrigine (LTG) has been widely prescribed as an antipsychotic drug, although it causes idiosyncratic drug-induced liver injury in humans." | 1.51 | Strain and interindividual differences in lamotrigine-induced liver injury in mice. ( Akai, S; Oda, S; Yokoi, T, 2019) |
| "On VPA 1000 mg/d, the seizure frequency decreased significantly." | 1.37 | Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome. ( Crespel, A; Gelisse, P; Genton, P; Pageaux, GP; Velizarova, R, 2011) |
| "Lamotrigine is a relatively new agent, and this report may provide useful insights on evaluating the clinical toxicology of this agent." | 1.30 | Lamotrigine overdose presenting as anticonvulsant hypersensitivity syndrome. ( Hollik, DA; Mylonakis, E; Rounds, S; Vittorio, CC, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Chalasani, N | 1 |
| Bonkovsky, HL | 1 |
| Stine, JG | 1 |
| Gu, J | 1 |
| Barnhart, H | 1 |
| Jacobsen, E | 1 |
| Björnsson, E | 1 |
| Fontana, RJ | 1 |
| Kleiner, DE | 1 |
| Hoofnagle, JH | 1 |
| Couper, MR | 1 |
| Brown, RM | 1 |
| Nath, S | 1 |
| Parida, A | 1 |
| Kelgeri, C | 1 |
| Kamitaki, BK | 1 |
| Minacapelli, CD | 1 |
| Zhang, P | 1 |
| Wachuku, C | 1 |
| Gupta, K | 1 |
| Catalano, C | 1 |
| Rustgi, V | 1 |
| Inaba, T | 1 |
| Sogawa, R | 1 |
| Mizoguchi, Y | 1 |
| Tateishi, H | 1 |
| Kunitake, Y | 1 |
| Kato, TA | 1 |
| Monji, A | 1 |
| Akai, S | 1 |
| Oda, S | 1 |
| Yokoi, T | 1 |
| Su-Yin, AN | 1 |
| Tai, WW | 1 |
| Olson, KR | 1 |
| Bushardt, RL | 1 |
| Ouellet, G | 1 |
| Tremblay, L | 1 |
| Marleau, D | 1 |
| Velizarova, R | 1 |
| Gelisse, P | 1 |
| Pageaux, GP | 1 |
| Genton, P | 1 |
| Crespel, A | 1 |
| Bhayana, H | 1 |
| Appasani, S | 1 |
| Thapa, BR | 1 |
| Das, A | 1 |
| Singh, K | 1 |
| Overstreet, K | 1 |
| Costanza, C | 1 |
| Behling, C | 1 |
| Hassanin, T | 1 |
| Masliah, E | 1 |
| Mecarelli, O | 1 |
| Pulitano, P | 1 |
| Mingoia, M | 1 |
| Ferretti, G | 1 |
| Rossi, M | 1 |
| Berloco, PB | 1 |
| Muda, AO | 1 |
| Fix, OK | 1 |
| Peters, MG | 1 |
| Davern, TJ | 1 |
| Delima, SI | 1 |
| Walsh, LE | 1 |
| Golomb, MR | 1 |
| Schmidt, D | 1 |
| Krämer, G | 1 |
| Gómez Caturla, A | 1 |
| Arteta Jiménez, M | 1 |
| Fernández Planelles, C | 1 |
| Portillo, J | 1 |
| Mylonakis, E | 1 |
| Vittorio, CC | 1 |
| Hollik, DA | 1 |
| Rounds, S | 1 |
| Sauvé, G | 1 |
| Bresson-Hadni, S | 1 |
| Prost, P | 1 |
| Le Calvez, S | 1 |
| Becker, MC | 1 |
| Galmiche, J | 1 |
| Carbillet, JP | 1 |
| Miguet, JP | 1 |
| Anderson, GD | 1 |
| O'Donohoe, NV | 1 |
6 reviews available for lamotrigine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Periportal necrosis and successful liver transplantation following Lamotrigine drug-induced liver injury in a child.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity Syndrome; Huma | 2023 |
Fulminant hepatitis induced by lamotrigine.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Female; Humans; La | 2009 |
Fatal progressive hepatic necrosis associated with lamotrigine treatment: a case report and literature review.
Topics: Adult; Anticonvulsants; Biopsy; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Fatal Outc | 2002 |
The new anticonvulsant drugs. Implications for avoidance of adverse effects.
Topics: Abnormalities, Drug-Induced; Anemia, Aplastic; Anticonvulsants; Chemical and Drug Induced Liver Inju | 1994 |
Children versus adults: pharmacokinetic and adverse-effect differences.
Topics: Adolescent; Age Factors; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Child, Pres | 2002 |
19 other studies available for lamotrigine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study.
Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Chemical and Drug Ind | 2022 |
Drug-induced liver injury associated with antiseizure medications from the FDA Adverse Event Reporting System (FAERS).
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Humans; Lamotrigine; Levetiracetam; Phenyto | 2021 |
Lamotrigine Rechallenge in Treatment-Resistant Bipolar Disorder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Antimanic Agents; Bipolar Disorder; Che | 2018 |
Strain and interindividual differences in lamotrigine-induced liver injury in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Lamotrigine; Mice; | 2019 |
Lamotrigine-associated reversible severe hepatitis: a case report.
Topics: Adult; Anticonvulsants; Antimanic Agents; Carbamazepine; Chemical and Drug Induced Liver Injury; Dep | 2008 |
Anticonvulsant hypersensitivity syndrome and drug-induced hepatic injury.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Lamo | 2009 |
Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Electroencephalography; Female; Fructose; H | 2011 |
Lamotrigine-induced vanishing bile duct syndrome in a child.
Topics: Anticonvulsants; Bile Duct Diseases; Bile Ducts; Chemical and Drug Induced Liver Injury; Child; Chol | 2012 |
Acute hepatitis associated with lamotrigine and managed with the molecular adsorbents recirculating system (Mars).
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Electroencephalography; Epile | 2005 |
Eosinophilic hepatitis caused by lamotrigine.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Eosinophilia; Female; Humans; Lamotr | 2006 |
Simultaneous toxicities in a child on multiple anticonvulsants.
Topics: Anticonvulsants; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, P | 2008 |
[Acute hepatitis associated with lamotrigine administration].
Topics: Acute Disease; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Humans; Lamotrigine; | 1998 |
Lamotrigine overdose presenting as anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Antimanic Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Hu | 1999 |
Acute hepatitis after lamotrigine administration.
Topics: Acute Disease; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Disseminated Intravas | 2000 |
Use of antiepileptic drugs in childhood epilepsy.
Topics: Adult; Aminocaproates; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Child, Presch | 1991 |