lamotrigine has been researched along with Ache in 45 studies
Excerpt | Relevance | Reference |
---|---|---|
" The 2 treatment periods began with an 8-week, double-blind titration period, during which the number of pills of study drug was increased until either total pain relief was achieved, 1 or more unmanageable adverse events were reported, or a maximum of 16 pills (400 mg of lamotrigine) were used daily." | 9.12 | A randomized, double-blind, placebo-controlled, two-period, crossover, pilot trial of lamotrigine in patients with central pain due to multiple sclerosis. ( Breuer, B; Guleyupoglu, N; Knotkova, H; Pappagallo, M; Portenoy, RK; Wallenstein, S, 2007) |
"Lamotrigine, a sodium channel blocker that selectively inhibits the neuronal release of glutamate, has been shown to produce analgesia in acute and chronic pain models in rats without causing noticeable sedation." | 9.09 | Effects of lamotrigine on pain-induced chemo-somatosensory evoked potentials. ( Klamt, JG; Posner, J, 1999) |
"Lamotrigine 200 mg/d reduced the median pain score to 5, compared to 7 during placebo (p = 0." | 9.09 | Lamotrigine for central poststroke pain: a randomized controlled trial. ( Andersen, G; Gottrup, H; Jensen, TS; Kristensen, BT; Vestergaard, K, 2001) |
"Randomised controlled trials (RCTs) of lamotrigine in acute, and chronic pain (including cancer pain) were identified from MEDLINE, EMBASE and CENTRAL up to January 2011." | 8.87 | Lamotrigine for acute and chronic pain. ( Derry, S; Moore, RA; Wiffen, PJ, 2011) |
"To assess the analgesic efficacy and adverse effects of the anticonvulsant lamotrigine for acute and chronic pain." | 8.84 | Lamotrigine for acute and chronic pain. ( Rees, J; Wiffen, PJ, 2007) |
"The effects of treatment with the anti-convulsant agents, lamotrigine and riluzole were compared with gabapentin in a rat experimental model of neuropathic pain." | 7.74 | A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain. ( Coderre, TJ; Kumar, N; Lefebvre, CD; Yu, JS, 2007) |
"Intrathecal (IT) lamotrigine, a sodium channel blocker which suppresses neuronal release of glutamate, has been shown to produce a long-lasting antihyperalgesic effect in the neuropathic pain models." | 7.71 | The thermal and mechanical anti-hyperalgesic effects of pre- versus post-intrathecal treatment with lamotrigine in a rat model of inflammatory pain. ( Buerkle, H; Lee, TH; Lin, SH; Wang, CJ; Wu, PC; Yang, LC, 2002) |
"Some opioid-resistant pain conditions can be alleviated by voltage-dependent Na(+) channel blockers such as lamotrigine." | 7.71 | Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage. ( Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM, 2001) |
"Outcome measures were the areas of secondary hyperalgesia to brush and von Frey hair stimulation and the painfulness of noxious thermal stimulation in nonsensitized skin." | 6.71 | A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization. ( Dahl, JB; Hoke, F; Maloney, A; Petersen, KL; Rowbotham, MC, 2003) |
"Intensive pain is difficult to control with standard analgesics." | 5.35 | Lamotrigine therapy for resistant pain in radicular lesions of cervical segments C4-C5 and C5-C6: a case report. ( Aleksić-Shihabi, A; Buca, A; Jukić, I; Titlić, M; Tonkić, A, 2009) |
"Pain associated with hyperalgesia of the affected area occurs in a number of conditions." | 5.30 | Lamotrigine for pain with hyperalgesia. ( Dennehy, F; Harbison, J; Keating, D, 1997) |
"Our study confirmed that pamidronate, prednisone, and guideline-recommended anticonvulsants were effective for reducing pain intensity for CPSP." | 5.22 | Pharmacotherapies for Central Post-Stroke Pain: A Systematic Review and Network Meta-Analysis. ( Bo, Z; Gangfeng, G; Jian, W; Jian, Y; Ke, H; Maoxia, L; Xiaojing, L; Xiaolan, L; Yan, L; Yang, F; Zhao, C, 2022) |
" The 2 treatment periods began with an 8-week, double-blind titration period, during which the number of pills of study drug was increased until either total pain relief was achieved, 1 or more unmanageable adverse events were reported, or a maximum of 16 pills (400 mg of lamotrigine) were used daily." | 5.12 | A randomized, double-blind, placebo-controlled, two-period, crossover, pilot trial of lamotrigine in patients with central pain due to multiple sclerosis. ( Breuer, B; Guleyupoglu, N; Knotkova, H; Pappagallo, M; Portenoy, RK; Wallenstein, S, 2007) |
"The anticonvulsant lamotrigine has been reported to be efficacious and well tolerated as monotherapy in the treatment of bipolar patients as well as in treatment-refractory bipolar disorder." | 5.10 | Lamotrigine as an augmentation agent in treatment-resistant depression. ( Barbee, JG; Jamhour, NJ, 2002) |
"Lamotrigine, a sodium channel blocker that selectively inhibits the neuronal release of glutamate, has been shown to produce analgesia in acute and chronic pain models in rats without causing noticeable sedation." | 5.09 | Effects of lamotrigine on pain-induced chemo-somatosensory evoked potentials. ( Klamt, JG; Posner, J, 1999) |
"Lamotrigine 200 mg/d reduced the median pain score to 5, compared to 7 during placebo (p = 0." | 5.09 | Lamotrigine for central poststroke pain: a randomized controlled trial. ( Andersen, G; Gottrup, H; Jensen, TS; Kristensen, BT; Vestergaard, K, 2001) |
" Overall, there was a low quality of evidence that gabapentin, pregabalin, amitriptyline, and venlafaxine were effective in reducing pain intensity in patients with cancer pain." | 4.95 | Pharmacological Treatment of Pain in Cancer Patients: The Role of Adjuvant Analgesics, a Systematic Review. ( de Graeff, A; Dijkstra, D; Jongen, JL; Mostovaya, I; van den Beuken-van Everdingen, MH; Vissers, KC, 2017) |
"Randomised controlled trials (RCTs) of lamotrigine in acute, and chronic pain (including cancer pain) were identified from MEDLINE, EMBASE and CENTRAL up to January 2011." | 4.87 | Lamotrigine for acute and chronic pain. ( Derry, S; Moore, RA; Wiffen, PJ, 2011) |
"To assess the analgesic efficacy and adverse effects of the anticonvulsant lamotrigine for acute and chronic pain." | 4.84 | Lamotrigine for acute and chronic pain. ( Rees, J; Wiffen, PJ, 2007) |
"The effects of treatment with the anti-convulsant agents, lamotrigine and riluzole were compared with gabapentin in a rat experimental model of neuropathic pain." | 3.74 | A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain. ( Coderre, TJ; Kumar, N; Lefebvre, CD; Yu, JS, 2007) |
"Intrathecal (IT) lamotrigine, a sodium channel blocker which suppresses neuronal release of glutamate, has been shown to produce a long-lasting antihyperalgesic effect in the neuropathic pain models." | 3.71 | The thermal and mechanical anti-hyperalgesic effects of pre- versus post-intrathecal treatment with lamotrigine in a rat model of inflammatory pain. ( Buerkle, H; Lee, TH; Lin, SH; Wang, CJ; Wu, PC; Yang, LC, 2002) |
"Some opioid-resistant pain conditions can be alleviated by voltage-dependent Na(+) channel blockers such as lamotrigine." | 3.71 | Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage. ( Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM, 2001) |
"The novel anti-epileptic drugs lamotrigine, felbamate and gabapentin were compared in rat experimental models of acute (tail flick) and chronic pain: the chronic constriction injury and spinal nerve ligation models." | 3.69 | The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain. ( Fontana, DJ; Gogas, KR; Hedley, LR; Hunter, JC; Jacobson, LO; Kassotakis, L; Thompson, J, 1997) |
"Outcome measures were the areas of secondary hyperalgesia to brush and von Frey hair stimulation and the painfulness of noxious thermal stimulation in nonsensitized skin." | 2.71 | A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization. ( Dahl, JB; Hoke, F; Maloney, A; Petersen, KL; Rowbotham, MC, 2003) |
"Gabapentin has demonstrated efficacy, specifically in painful diabetic neuropathy and postherpetic neuralgia." | 2.41 | Use of anticonvulsants for treatment of neuropathic pain. ( Backonja, MM, 2002) |
"Comorbid diagnosis of headache predicted use of topiramate and VPA, bipolar disease predicted use of LMT and VPA, pain predicted gabapentin, and schizophrenia was associated with VPAs use." | 1.91 | Prescribing Trends of Antiseizure Drugs in Women Veterans With Epilepsy. ( Amuan, ME; Henion, A; Lopez, MR; Panahi, S; Pugh, MJ; VanCott, AC, 2023) |
"Lamotrigine was the most frequently initiated drug in psychiatry, in both boys and girls." | 1.48 | Utilization of Antiepileptic Medicines in Swedish Children and Adolescents with Different Diagnoses. ( Karlsson Lind, L; von Euler, M; Wettermark, B; Wide, K, 2018) |
"Intensive pain is difficult to control with standard analgesics." | 1.35 | Lamotrigine therapy for resistant pain in radicular lesions of cervical segments C4-C5 and C5-C6: a case report. ( Aleksić-Shihabi, A; Buca, A; Jukić, I; Titlić, M; Tonkić, A, 2009) |
"Pain associated with hyperalgesia of the affected area occurs in a number of conditions." | 1.30 | Lamotrigine for pain with hyperalgesia. ( Dennehy, F; Harbison, J; Keating, D, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (22.22) | 18.2507 |
2000's | 27 (60.00) | 29.6817 |
2010's | 5 (11.11) | 24.3611 |
2020's | 3 (6.67) | 2.80 |
Authors | Studies |
---|---|
Yang, J | 1 |
Gharagozloo, P | 1 |
Yao, J | 1 |
Ilyin, VI | 3 |
Carter, RB | 3 |
Nguyen, P | 3 |
Robledo, S | 2 |
Woodward, RM | 2 |
Hogenkamp, DJ | 2 |
Shao, B | 1 |
Victory, S | 1 |
Goehring, RR | 1 |
Sun, Q | 1 |
Hogenkamp, D | 1 |
Hodges, DD | 1 |
Islam, K | 1 |
Sha, D | 1 |
Zhang, C | 1 |
Sakellaropoulos, G | 1 |
Yogeeswari, P | 1 |
Ragavendran, JV | 1 |
Sriram, D | 1 |
Nageswari, Y | 1 |
Kavya, R | 1 |
Sreevatsan, N | 1 |
Vanitha, K | 1 |
Stables, J | 1 |
Jarvis, MF | 1 |
Honore, P | 1 |
Shieh, CC | 1 |
Chapman, M | 1 |
Joshi, S | 1 |
Zhang, XF | 1 |
Kort, M | 1 |
Carroll, W | 1 |
Marron, B | 1 |
Atkinson, R | 1 |
Thomas, J | 1 |
Liu, D | 1 |
Krambis, M | 1 |
Liu, Y | 1 |
McGaraughty, S | 1 |
Chu, K | 1 |
Roeloffs, R | 1 |
Zhong, C | 1 |
Mikusa, JP | 1 |
Hernandez, G | 1 |
Gauvin, D | 1 |
Wade, C | 1 |
Zhu, C | 1 |
Pai, M | 1 |
Scanio, M | 1 |
Shi, L | 1 |
Drizin, I | 1 |
Gregg, R | 1 |
Matulenko, M | 1 |
Hakeem, A | 1 |
Gross, M | 1 |
Johnson, M | 1 |
Marsh, K | 1 |
Wagoner, PK | 1 |
Sullivan, JP | 1 |
Faltynek, CR | 1 |
Krafte, DS | 1 |
Bo, Z | 1 |
Jian, Y | 1 |
Yan, L | 1 |
Gangfeng, G | 1 |
Xiaojing, L | 1 |
Xiaolan, L | 1 |
Zhao, C | 1 |
Ke, H | 1 |
Yang, F | 1 |
Maoxia, L | 1 |
Jian, W | 1 |
Lopez, MR | 1 |
VanCott, AC | 1 |
Amuan, ME | 1 |
Panahi, S | 1 |
Henion, A | 1 |
Pugh, MJ | 1 |
Vandevelde, A | 1 |
Benbrika, S | 1 |
Madigand, J | 1 |
Dollfus, S | 1 |
Karlsson Lind, L | 1 |
Wide, K | 1 |
Wettermark, B | 1 |
von Euler, M | 1 |
Szabo, AZ | 1 |
Bocsan, IC | 1 |
Suciu, S | 1 |
Buzoianu, AD | 1 |
van den Beuken-van Everdingen, MH | 1 |
de Graeff, A | 1 |
Jongen, JL | 1 |
Dijkstra, D | 1 |
Mostovaya, I | 1 |
Vissers, KC | 1 |
Titlic, M | 2 |
Jukic, I | 2 |
Tonkic, A | 2 |
Josipovic-Jelic, Z | 1 |
Boschi, V | 1 |
Mihalj, M | 1 |
Punda, A | 1 |
Sindrup, SH | 1 |
Buca, A | 1 |
Aleksić-Shihabi, A | 1 |
Scrivani, S | 1 |
Wallin, D | 1 |
Moulton, EA | 1 |
Cole, S | 1 |
Wasan, AD | 1 |
Lockerman, L | 1 |
Bajwa, Z | 1 |
Upadhyay, J | 1 |
Becerra, L | 1 |
Borsook, D | 1 |
Wiffen, PJ | 2 |
Derry, S | 1 |
Moore, RA | 1 |
Lee, TH | 1 |
Wang, CJ | 1 |
Wu, PC | 1 |
Buerkle, H | 1 |
Lin, SH | 1 |
Yang, LC | 1 |
Laughlin, TM | 1 |
Tram, KV | 1 |
Wilcox, GL | 1 |
Birnbaum, AK | 1 |
Barbee, JG | 1 |
Jamhour, NJ | 1 |
Backonja, MM | 1 |
Keswani, SC | 1 |
Pardo, CA | 1 |
Cherry, CL | 1 |
Hoke, A | 1 |
McArthur, JC | 1 |
Yen, HL | 1 |
Chan, W | 1 |
Petersen, KL | 1 |
Maloney, A | 1 |
Hoke, F | 1 |
Dahl, JB | 1 |
Rowbotham, MC | 1 |
Hong, HB | 1 |
Xu, RJ | 1 |
Lindia, JA | 1 |
Köhler, MG | 1 |
Martin, WJ | 1 |
Abbadie, C | 1 |
Reiss, JP | 1 |
Sam, D | 1 |
Sareen, J | 1 |
Pomonis, JD | 1 |
Whiteside, GT | 1 |
Harrison, JE | 1 |
Pearson, MS | 1 |
Mark, L | 1 |
Turchin, PI | 1 |
Gottshall, S | 1 |
Olanrewaju, S | 1 |
Benjamin, E | 1 |
Coderre, TJ | 1 |
Kumar, N | 1 |
Lefebvre, CD | 1 |
Yu, JS | 1 |
Rees, J | 1 |
Breuer, B | 1 |
Pappagallo, M | 1 |
Knotkova, H | 1 |
Guleyupoglu, N | 1 |
Wallenstein, S | 1 |
Portenoy, RK | 1 |
Bras, M | 1 |
Harbison, J | 1 |
Dennehy, F | 1 |
Keating, D | 1 |
Hunter, JC | 1 |
Gogas, KR | 1 |
Hedley, LR | 1 |
Jacobson, LO | 1 |
Kassotakis, L | 1 |
Thompson, J | 1 |
Fontana, DJ | 1 |
Canavero, S | 1 |
Bonicalzi, V | 1 |
Kukushkin, ML | 1 |
Danilova, EI | 1 |
Grafova, VN | 1 |
Smirnova, VS | 1 |
Reshetniak, VK | 1 |
Webb, J | 1 |
Kamali, F | 1 |
McCleane, G | 2 |
Cianchetti, C | 1 |
Zuddas, A | 1 |
Randazzo, AP | 1 |
Perra, L | 1 |
Marrosu, MG | 1 |
Klamt, JG | 1 |
Posner, J | 1 |
Carrieri, PB | 1 |
Bonuso, S | 1 |
Bruno, R | 1 |
Vincitorio, CM | 1 |
Caruso, G | 1 |
Devulder, J | 2 |
De Laat, M | 1 |
Leandri, M | 1 |
Lundardi, G | 1 |
Inglese, M | 1 |
Messmer-Uccelli, M | 1 |
Mancardi, GL | 1 |
Gottlieb, A | 1 |
Solaro, C | 1 |
Vestergaard, K | 1 |
Andersen, G | 1 |
Gottrup, H | 1 |
Kristensen, BT | 1 |
Jensen, TS | 1 |
Blackburn-Munro, G | 1 |
Dickinson, T | 1 |
Fleetwood-Walker, SM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparison of Oral Lamotrigine Versus Pregabalin for Control of Acute and Chronic Pain Following Modified Radical Mastectomy: Controlled Double-blind Study[NCT03419949] | 0 participants | Expanded Access | Available | ||||
Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management: A Randomized Controlled Trial of Efficacy and Safety[NCT05427058] | 36 participants (Anticipated) | Interventional | 2022-08-01 | Not yet recruiting | |||
Evaluation of Lamotrigine on Neuropathic Facial Pain Using fMRI[NCT00243152] | 6 participants (Actual) | Interventional | 2005-10-31 | Completed | |||
Efficacy and Safety of Antidepressant Augmentation With Lamotrigine in Patients With Treatment-Resistant Depression[NCT00652171] | Phase 3 | 34 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
fMRI scans acquired Stimuli Type: Brush Stimulation Regions: Face (V2) Right and Left Sides Rating: Pain/ unpleasantness fMRI scans acquired Stimuli Type: Cold, threshold -1°C Stimulation Regions: Face (V2) Right and Left Sides Rating: Pain/ unpleasantness **Extra time allotted for probe repositioning** fMRI scans acquired Stimuli Type: Heat, threshold +1°C Stimulation Regions: Face (V2) Right and Left Sides Rating: Pain/ unpleasantness **Extra time allotted for probe repositioning** Cortical, subcortical, and brain stem sensory regions Z-scores Increase or decrease in activation as affected by the drug (NCT00243152)
Timeframe: Week 10 during scanning session
Intervention | Z-statistic (Number) | ||||||
---|---|---|---|---|---|---|---|
Heat Affected Thalamus (10,-14,8) | Heat Affected Post-Central (-56,-12,28) | Cold Affected Post-Central (68, -8, 32) | Cold Affected Thalamus (-4, -8, 0) | Brush Affected Post-Central (66,-16,14) | Brush Affected Thalamus (-14,-22, 4) | Brush Affected Spinal Trigeminal Nucles(2,-48,-68) | |
Lamotrigine vs Placebo | -2.9294 | -2.7323 | -2.5114 | -3.033 | 3.905 | -3.791 | 2.9058 |
"Quantitative Sensory Testing (QST)~Stimuli Type: Heat, Cold, Brush Stimulation Regions: Face Affected and contralateral Unaffected mirror area Rating: Pain/ unpleasantness Stimuli Type: Cold, threshold -1°C Stimulation Regions: Face Affected and contralateral Unaffected mirror area Rating: Pain/ unpleasantness Stimuli Type: Heat, threshold +1°C Stimulation Regions: Face Affected and contralateral Unaffected mirror area Rating: Pain/ unpleasantness~Ratings on a likert scale of 0-10 with 0 being defined as no pain and 10 being defined as worst possible pain" (NCT00243152)
Timeframe: week 10 (during the scan)
Intervention | scores on a pain scale (Mean) | |||||
---|---|---|---|---|---|---|
Heat Affected | Heat Unaffected | Cold Affected | Cold Unaffected | Brush Affected | Brush Unaffected | |
Lamotrigine | 3.2 | 3 | 2.1 | 2.2 | 2.8 | 1.2 |
Placebo | 5.5 | 4 | 2.5 | 1.1 | 3.9 | .4 |
10 reviews available for lamotrigine and Ache
Article | Year |
---|---|
Pharmacotherapies for Central Post-Stroke Pain: A Systematic Review and Network Meta-Analysis.
Topics: Anticonvulsants; Etanercept; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Pain; Pamidr | 2022 |
Common mechanisms involved in manic switch and pain relief induced by lamotrigine: A case report and a literature review.
Topics: Anticonvulsants; Bipolar Disorder; Humans; Lamotrigine; Pain; Pain Management | 2021 |
Pharmacological Treatment of Pain in Cancer Patients: The Role of Adjuvant Analgesics, a Systematic Review.
Topics: Amines; Analgesics; Anticonvulsants; Antidepressive Agents; Chemotherapy, Adjuvant; Cyclohexanecarbo | 2017 |
Lamotrigine in the treatment of pain syndromes and neuropathic pain.
Topics: Analgesics; Anticonvulsants; Humans; Lamotrigine; Neuralgia; Pain; Triazines | 2008 |
Lamotrigine for acute and chronic pain.
Topics: Acute Disease; Analgesics; Chronic Disease; Humans; Lamotrigine; Pain; Randomized Controlled Trials | 2011 |
Use of anticonvulsants for treatment of neuropathic pain.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; | 2002 |
HIV-associated sensory neuropathies.
Topics: Analgesics; Anti-HIV Agents; HIV Infections; Humans; Lamotrigine; Nerve Growth Factors; Pain; Periph | 2002 |
[Progress on painful diabetic peripheral neuropathy treated by integrative medicine].
Topics: Amines; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Blood Glucose; Cyclohe | 2005 |
Lamotrigine for acute and chronic pain.
Topics: Acute Disease; Analgesics; Anticonvulsants; Chronic Disease; Humans; Lamotrigine; Pain; Randomized C | 2007 |
[Psychopharmacotherapy in psychiatric comorbidities among patients with chronic pain].
Topics: Amines; Analgesics; Anticonvulsants; Bupropion; Chronic Disease; Cyclohexanecarboxylic Acids; Dopami | 2007 |
9 trials available for lamotrigine and Ache
Article | Year |
---|---|
A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study.
Topics: Adult; Amines; Anticonvulsants; Brain; Cold Temperature; Cross-Over Studies; Cyclohexanecarboxylic A | 2010 |
Lamotrigine as an augmentation agent in treatment-resistant depression.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Anxiety Disorders; Bipolar Disorder; Chronic Disease | 2002 |
A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization.
Topics: Adult; Analgesics, Opioid; Anticonvulsants; Capsaicin; Double-Blind Method; Drug Therapy, Combinatio | 2003 |
A randomized, double-blind, placebo-controlled, two-period, crossover, pilot trial of lamotrigine in patients with central pain due to multiple sclerosis.
Topics: Anticonvulsants; Cross-Over Studies; Double-Blind Method; Female; Humans; Lamotrigine; Male; Middle | 2007 |
Analgesic effects of lamotrigine and phenytoin on cold-induced pain: a crossover placebo-controlled study in healthy volunteers.
Topics: Adult; Anticonvulsants; Blood Pressure; Cold Temperature; Cross-Over Studies; Double-Blind Method; F | 1998 |
Effects of lamotrigine on pain-induced chemo-somatosensory evoked potentials.
Topics: Administration, Oral; Adult; Analgesics; Carbon Dioxide; Cross-Over Studies; Double-Blind Method; Ev | 1999 |
200 mg daily of lamotrigine has no analgesic effect in neuropathic pain: a randomised, double-blind, placebo controlled trial.
Topics: Adult; Analgesics; Anticonvulsants; Double-Blind Method; Drug Administration Schedule; Female; Human | 1999 |
Lamotrigine in trigeminal neuralgia secondary to multiple sclerosis.
Topics: Analgesics; Analgesics, Non-Narcotic; Carbamazepine; Female; Humans; Lamotrigine; Male; Middle Aged; | 2000 |
Lamotrigine for central poststroke pain: a randomized controlled trial.
Topics: Adult; Aged; Analysis of Variance; Double-Blind Method; Female; Humans; Lamotrigine; Male; Middle Ag | 2001 |
26 other studies available for lamotrigine and Ache
Article | Year |
---|---|
3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
Topics: Analgesics; Animals; Cell Line; Humans; Male; Pain; Patch-Clamp Techniques; Peripheral Nervous Syste | 2004 |
Phenoxyphenyl pyridines as novel state-dependent, high-potency sodium channel inhibitors.
Topics: Analgesics; Animals; Animals, Newborn; Brain; Cell Line; Humans; In Vitro Techniques; Male; NAV1.2 V | 2004 |
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; | 2007 |
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
Topics: Action Potentials; Analgesics; Aniline Compounds; Animals; Capsaicin; Evoked Potentials; Furans; Gan | 2007 |
Prescribing Trends of Antiseizure Drugs in Women Veterans With Epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Levetiracetam | 2023 |
Utilization of Antiepileptic Medicines in Swedish Children and Adolescents with Different Diagnoses.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Prescriptions; Drug Utilization; Epilepsy | 2018 |
Comparative animal study of the antinociceptive efficacy of lamotrigine and gabapentin for the management of pain.
Topics: Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; gamma-Aminobutyric Acid; Lamotrigine | 2015 |
Nicotinic acetylcholine receptor agonism: progress in the management of neuropathic pain?
Topics: Azetidines; Excitatory Amino Acid Antagonists; Humans; Lamotrigine; Nicotinic Agonists; Pain; Periph | 2009 |
Lamotrigine therapy for resistant pain in radicular lesions of cervical segments C4-C5 and C5-C6: a case report.
Topics: Adult; Anticonvulsants; Cervical Vertebrae; Female; Humans; Intervertebral Disc Displacement; Lamotr | 2009 |
The thermal and mechanical anti-hyperalgesic effects of pre- versus post-intrathecal treatment with lamotrigine in a rat model of inflammatory pain.
Topics: Analgesics; Animals; Arthritis, Experimental; Dose-Response Relationship, Drug; Inflammation; Inject | 2002 |
Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.
Topics: Acetates; Acute Disease; Adrenergic alpha-Agonists; Amines; Analgesics, Non-Narcotic; Analgesics, Op | 2002 |
An East-West approach to the management of central post-stroke pain.
Topics: Acetates; Acupuncture; Aged; Amines; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Secon | 2003 |
Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Gan | 2005 |
Psychosis in multiple sclerosis associated with left temporal lobe lesions on serial MRI scans.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Delusions; Excitatory Amino Acid Antagonists; Female; | 2006 |
Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states.
Topics: Animals; Carbamazepine; Humans; Hyperalgesia; Lamotrigine; Male; Motor Activity; Pain; Pyrimidines; | 2006 |
A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Cold Temperature; Cyclohexanecarboxylic Acids; Disease | 2007 |
Lamotrigine for pain with hyperalgesia.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Female; Humans; Hyperalgesia; Lamotrigine; Male; Pain; Tri | 1997 |
The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain.
Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Anticonvulsants; Chronic Disease; Cyclohexanec | 1997 |
Lamotrigine control of central pain.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anticonvulsants; Central Nervous System Diseases; Female | 1996 |
[Effect of lamotrigine on development of neurogenic pain syndrome in rats].
Topics: Analgesics; Animals; Anticonvulsants; Convulsants; Lamotrigine; Neurons; Pain; Pain Measurement; Pen | 1998 |
Lamotrigine can reduce neurogenic pain associated with multiple sclerosis.
Topics: Adult; Analgesics; Female; Humans; Lamotrigine; Multiple Sclerosis; Pain; Triazines | 1998 |
Lamotrigine adjunctive therapy in painful phenomena in MS: preliminary observations.
Topics: Analgesics; Female; Humans; Lamotrigine; Male; Multiple Sclerosis; Pain; Triazines | 1999 |
Efficacy of lamotrigine on sensory symptoms and pain in peripheral neuropathies.
Topics: Aged; Anticonvulsants; Female; Humans; Lamotrigine; Male; Middle Aged; Pain; Peripheral Nervous Syst | 1999 |
Lamotrigine in the treatment of chronic refractory neuropathic pain.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Chronic Disease; Drug Therapy, Combination; Female; Hum | 2000 |
Is 200mg lamotrigine daily analgesic or not?
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Humans; Lamotrigine; Pain; Triazines | 2000 |
Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage.
Topics: Action Potentials; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Calcium Channel Blockers; Chole | 2001 |