Page last updated: 2024-08-24

lamivudine and Disease Models, Animal

lamivudine has been researched along with Disease Models, Animal in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (14.29)	18.2507
2000's	19 (54.29)	29.6817
2010's	6 (17.14)	24.3611
2020's	5 (14.29)	2.80

Authors

Authors	Studies
Butler, SD; Cote, PJ; George, AL; Gerin, JL; Menne, S; Tennant, BC; Tochkov, IA; Xiong, S; Zhu, Y	1
Chang, J; Liu, B; Liu, Y; Lu, J; Ma, H; Peng, Y; Qiao, Y; Song, C; Wang, J; Wu, J; Yu, W	1
Clotet, B; Dierssen, M; Elizalde-Torrent, A; Martinez de Lagran, M; Paredes, R	1
Ávila, J; Hernández, F; Vallés-Saiz, L	1
Davis, CC; Hassounah, S; Heredia, A; Kashanchi, F; Le, NM; Medina-Moreno, S; Mesplede, T; Oliveira, M; Zapata, JC	1
Afolayan, S; Agumah, R; Akang, E; Akanmu, AS; Dosumu, O	1
Chayama, K; Chung, TL; Dahari, H; Durso-Cain, K; Ishida, Y; Perelson, AS; Reinharz, V; Tateno, C; Tsuge, M; Uprichard, SL	1
Allweiss, L; Beninati, C; Dandri, M; Giersch, K; Kah, J; Lohse, AW; Lütgehetmann, M; Petersen, J; Pollicino, T; Raffa, G; Urban, S; Volz, T	1
Dong, X; Meng, H; Tian, W; Wang, G; Wei, G; Wu, X; Yuchi, J	1
Chen, M; Girgis, S; Graham, D; Mason, AL; McDougall, C; Montano-Loza, A; Sharon, D; Sis, B; Wasilenko, ST; Zhang, G	1
Akkina, R; Akkina, SR; Habu, Y; Hu, S; Kumar, DM; Neff, CP; Seki, T	1
Fang, Y; Hu, Q; Yang, DL; Zhang, XY; Zhang, ZH; Zhang, ZM	1
Benech, H; Bourry, O; Brochard, P; Calvo, J; Dereudre-Bosquet, N; Kazanji, M; Le Grand, R; Makuwa, M; Martinon, F; Souquiere, S	1
Cook, A; Divi, RL; Einem, TL; Fletcher, SL; Harbaugh, JW; Harbaugh, SW; Kuo, MM; Nagashima, K; Poirier, MC; Shockley, ME; St Claire, MC	1
Bock, CT; Dienes, HP; Klein, C; Kubicka, S; Locarnini, S; Manns, MP; Trautwein, C; Wedemeyer, H; Wüstefeld, T	1
Cote, PJ; Delaney, WE; Gerin, JL; Jacob, JR; Korba, BE; Tennant, BC; Toshkov, I	1
Choi, BC; Lei, XY; Li, D; Men, K; Xu, DZ; Yan, YP; Zhang, JX	1
Cook, JE; Dasgupta, S; Gorry, PR; Middaugh, LD; Terry, EC; Tyor, WR; Wesselingh, SL	1
Han, SH	1
Lei, XY; Li, D; Men, K; Xu, DZ; Yan, YP; Zhang, JX	1
Chen, HS; Feng, LL; Guo, XB; He, JY; Yang, RY; Zhang, FX; Zhu, YT	1
Clayton, MM; Feitelson, MA; Schinazi, RF; Sun, B	1
Chi, H; Dahmen, U; Dirsch, O; Gerlich, WH; Glebe, D; He, L; Kemper, T; Lorenz, H; Lu, M; Roggendorf, M; Wen, Y; Xu, Y; Yao, X	1
Main, J; McCarron, B; Thomas, HC	1
Arazi, J; Ben-Moshe, O; Berr, S; Burakova, T; Dagan, S; Eid, A; Eren, R; Galun, E; Gillard, J; Ilan, E; Jurim, O; Lubin, I; Mansour, TS; Neville, L; Nussbaum, O; Reisner, Y; Shouval, D; Yuen, L	1
Bailey, KW; Korba, BE; Morrey, JD; Sidwell, RW	1
Gendelman, HE; Lanier, ER; Limoges, J; McClernon, DR; Persidsky, Y; Poluektova, L; Rasmussen, J; Ratanasuwan, W; Zelivyanskaya, M	1
Bare, C; Bedard, J; Bogan, MR; Buckheit, RW; Gobbi, A; Linquist-Stepps, VD; McCune, JM; Moreno, ME; Rando, RF; Stoddart, CA	1
Korba, BE; Morrey, JD; Sidwell, RW	1
Cote, P; Gerin, JL; Hornbuckle, W; Korba, BE; Schinazi, R; Tennant, BC	1
Jia, Y; Liu, G; Ren, H; Wang, H; Xiong, Y; Zhang, D; Zhuo, Z	1
Heathcote, EJ; Hoofnagle, JH; Lok, AS	1
Chen, Y; Guo, S; Huang, A; Qi, Z	1
Julander, JG; Morrey, JD; Sidwell, RW	1

Reviews

4 review(s) available for lamivudine and Disease Models, Animal

Article	Year
Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B. Expert opinion on investigational drugs, 2005, Volume: 14, Issue:4 Topics: Animals; Antiviral Agents; Disease Models, Animal; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine	2005
Treatment of chronic viral hepatitis. Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:6 Topics: 2-Aminopurine; Animals; Antimetabolites; Antiviral Agents; Carcinoma, Hepatocellular; Disease Models, Animal; Drug Therapy, Combination; Ducks; Famciclovir; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis, Animal; Humans; Immunologic Factors; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Marmota; Poultry Diseases; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured	1998
Transgenic mice as a chemotherapeutic model for hepatitis B virus infection. Antiviral therapy, 1998, Volume: 3, Issue:Suppl 3 Topics: Administration, Oral; Animals; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Genome, Viral; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B Virus, Woodchuck; Humans; Interferon-alpha; Lamivudine; Mice; Mice, Transgenic; Polymerase Chain Reaction; Sex Factors; Time Factors; Viral Load; Virus Replication; Zidovudine	1998
Management of hepatitis B: 2000--summary of a workshop. Gastroenterology, 2001, Volume: 120, Issue:7 Topics: Animals; Disease Models, Animal; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Hepatitis B; Hepatitis B Vaccines; Humans; Interferon-alpha; Lamivudine; Liver Transplantation; Recurrence	2001

Other Studies

31 other study(ies) available for lamivudine and Disease Models, Animal

Article	Year
Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Adenine; Animals; Antigens, Viral; Antiviral Agents; Deoxycytidine; Disease Models, Animal; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Marmota; Organophosphonates; RNA, Viral; Rodent Diseases; Tenofovir; Virus Replication	2008
Design, synthesis, and biological evaluation of new 1,2,3-triazolo-2'-deoxy-2'-fluoro- 4'-azido nucleoside derivatives as potent anti-HBV agents. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Animals; Antiviral Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Ducks; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Hepatitis B Virus, Duck; Humans; Models, Molecular; Molecular Structure; Monosaccharides; Nucleosides; Structure-Activity Relationship; Triazoles; Virus Replication	2018
Lamivudine, a reverse transcriptase inhibitor, rescues cognitive deficits in a mouse model of down syndrome. Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:15 Topics: Animals; Cognition; Disease Models, Animal; Down Syndrome; Lamivudine; Mice; Mice, Transgenic; Reverse Transcriptase Inhibitors	2022
Lamivudine (3TC), a Nucleoside Reverse Transcriptase Inhibitor, Prevents the Neuropathological Alterations Present in Mutant Tau Transgenic Mice. International journal of molecular sciences, 2023, Jul-06, Volume: 24, Issue:13 Topics: Animals; Disease Models, Animal; HeLa Cells; Humans; Lamivudine; Mice; Mice, Transgenic; Reverse Transcriptase Inhibitors; tau Proteins; Tauopathies	2023
Lamivudine-resistant HIV Journal of global antimicrobial resistance, 2020, Volume: 20 Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Combinations; Heterocyclic Compounds, 3-Ring; HIV; HIV Infections; Humans; Lamivudine; Mice; Mutation; Oxazines; Piperazines; Pyridones; Treatment Outcome	2020
Modeling cerebellar limb dysmetria and impaired spatial memory in rats using lamivudine: A preliminary study. Journal of chemical neuroanatomy, 2020, Volume: 109 Topics: Alkynes; Animals; Benzoxazines; Cerebellar Ataxia; Cyclopropanes; Disease Models, Animal; Lamivudine; Male; Maze Learning; Rats; Rats, Wistar; Spatial Memory; Tenofovir	2020
Understanding Hepatitis B Virus Dynamics and the Antiviral Effect of Interferon Alpha Treatment in Humanized Chimeric Mice. Journal of virology, 2021, 06-24, Volume: 95, Issue:14 Topics: Animals; Antiviral Agents; Child, Preschool; Disease Models, Animal; DNA, Viral; Female; Hepatitis B; Hepatitis B virus; Humans; Infant; Interferon-alpha; Kinetics; Lamivudine; Liver Transplantation; Male; Mice, SCID; Models, Theoretical; Polyethylene Glycols; Recombinant Proteins; Serum Albumin; Transplantation Chimera	2021
Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo. Gut, 2018, Volume: 67, Issue:3 Topics: Animals; Cell Division; Cell Proliferation; Chimera; Disease Models, Animal; DNA, Circular; DNA, Viral; Hepatitis B Core Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Humans; Keratin-18; Lamivudine; Lipopeptides; Mice; Primary Cell Culture; Recurrence; Reverse Transcriptase Inhibitors; Viral Load; Virus Integration; Virus Replication	2018
[Anti-HBV effect of nucleotide analogues on mouse model of chronic HBV infection mediated by recombinant adeno-associated virus 8]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2013, Volume: 29, Issue:1 Topics: Animals; Antiviral Agents; Dependovirus; Disease Models, Animal; Genetic Vectors; Genome, Viral; Guanine; Hepatitis B Antibodies; Hepatitis B virus; Hepatitis B, Chronic; Lamivudine; Mice; Mice, Inbred C57BL; Nucleotides; Transduction, Genetic; Virus Replication	2013
Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease. Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:4 Topics: Amino Acid Sequence; Animals; Anti-Retroviral Agents; Biomarkers; Cholangitis; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Lamivudine; Liver Cirrhosis, Biliary; Lopinavir; Mammary Tumor Virus, Mouse; Mice, Inbred NOD; Molecular Sequence Data; Protease Inhibitors; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Time Factors; Tumor Virus Infections; Viral Load; Zidovudine	2015
A humanized mouse model for HIV-2 infection and efficacy testing of a single-pill triple-drug combination anti-retroviral therapy. Virology, 2017, 01-15, Volume: 501 Topics: Animals; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Dideoxynucleosides; Disease Models, Animal; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-2; Humans; Lamivudine; Mice; Mice, Inbred BALB C; Oxazines; Piperazines; Pyridones	2017
[Establishment of an in vivo model for duck hepatitis B virus infection using Hubei duckling]. Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2008, Volume: 22, Issue:2 Topics: Animals; Animals, Newborn; Disease Models, Animal; DNA, Viral; Ducks; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Lamivudine; Liver; Reverse Transcriptase Inhibitors; Viremia	2008
Prevention of vaginal simian immunodeficiency virus transmission in macaques by postexposure prophylaxis with zidovudine, lamivudine and indinavir. AIDS (London, England), 2009, Feb-20, Volume: 23, Issue:4 Topics: Administration, Oral; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Indinavir; Injections, Subcutaneous; Lamivudine; Macaca fascicularis; Sexually Transmitted Diseases, Viral; Simian Acquired Immunodeficiency Syndrome; Vagina; Viral Load; Viremia; Zidovudine	2009
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs). Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:1 Topics: Animals; Animals, Newborn; Cerebral Cortex; Didanosine; Disease Models, Animal; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Lamivudine; Maternal Exposure; Mitochondria, Liver; Oxidative Phosphorylation; Pregnancy; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2010
Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA. Gastroenterology, 2003, Volume: 125, Issue:1 Topics: Adenine; Animals; Capsid; Combined Modality Therapy; Disease Models, Animal; Gene Expression Regulation, Viral; Genetic Therapy; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Lamivudine; Liver; Male; Mice; Mice, Inbred Strains; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; Specific Pathogen-Free Organisms; Virus Replication	2003
Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model. Antiviral research, 2004, Volume: 63, Issue:2 Topics: Adenine; Administration, Oral; Amino Acid Motifs; Amino Acid Substitution; Animals; Antiviral Agents; Disease Models, Animal; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis B; Hepatitis B Virus, Woodchuck; Lamivudine; Marmota; Mutation, Missense; Organophosphonates; Protein Structure, Tertiary; Viremia; Virus Replication	2004
Preliminary study on the efficacy and safety of lamivudine and interferon alpha therapy in decreasing serum HBV DNA level in HBV positive transgenic mice during pregnancy. Journal of medical virology, 2005, Volume: 76, Issue:2 Topics: Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Female; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Interferon-alpha; Lamivudine; Mice; Mice, Transgenic; Pregnancy; Pregnancy Complications, Infectious; Viremia	2005
Highly active antiretroviral therapy and human immunodeficiency virus encephalitis. Annals of neurology, 2005, Volume: 57, Issue:6 Topics: AIDS Dementia Complex; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Disease Models, Animal; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Viral Load; Zidovudine	2005
[Study on efficacy and safety of lamivudine and interferon-alpha in treatment of hepatitis B virus transgenic mice with pregnancy]. Zhonghua fu chan ke za zhi, 2005, Volume: 40, Issue:5 Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Administration Routes; Female; Hepatitis B; Hepatitis B virus; Interferon-alpha; Lamivudine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy; Pregnancy Complications, Infectious; Random Allocation; Viral Load	2005
Mutations outside the YMDD motif in the P protein can also cause DHBV resistant to Lamivudine. World journal of gastroenterology, 2005, Jul-21, Volume: 11, Issue:27 Topics: Amino Acid Sequence; Animals; Chick Embryo; Disease Models, Animal; Drug Resistance, Viral; Ducks; Gene Products, pol; Hepatitis B; Hepatitis B virus; Lamivudine; Molecular Sequence Data; Reverse Transcriptase Inhibitors	2005
Development of a novel mouse model to evaluate drug candidates against hepatitis B virus. Antiviral chemistry & chemotherapy, 2007, Volume: 18, Issue:4 Topics: Adenine; Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatitis B; Hepatitis B virus; Lamivudine; Mice; Mice, Nude; Organophosphonates; Reproducibility of Results; Tenofovir	2007
Combination of an antiviral drug and immunomodulation against hepadnaviral infection in the woodchuck model. Journal of virology, 2008, Volume: 82, Issue:5 Topics: Animals; Antiviral Agents; Disease Models, Animal; Hepadnaviridae Infections; Lamivudine; Marmota; Plasmids; Vaccines, DNA	2008
The hepatitis B virus-trimera mouse: a model for human HBV infection and evaluation of anti-HBV therapeutic agents. Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:2 Topics: Animals; Antibodies, Viral; Antiviral Agents; Deoxycytidine; Disease Models, Animal; DNA, Viral; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Kidney; Lamivudine; Liver; Liver Transplantation; Mice; Mice, Inbred NOD; Mice, SCID; Polymerase Chain Reaction; RNA, Messenger; Serum Albumin; Viremia	1999
Utilization of transgenic mice replicating high levels of hepatitis B virus for antiviral evaluation of lamivudine. Antiviral research, 1999, Volume: 42, Issue:2 Topics: Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis, Viral, Animal; Humans; Lamivudine; Male; Mice; Mice, Transgenic; Time Factors; Treatment Outcome; Virus Replication; Zidovudine	1999
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice. Neurology, 2000, Jan-25, Volume: 54, Issue:2 Topics: AIDS Dementia Complex; Animals; Cells, Cultured; Didanosine; Dideoxynucleosides; Disease Models, Animal; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine	2000
Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Animals; Anti-HIV Agents; Deoxycytidine; Disease Models, Animal; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Mice; Mice, SCID; Reverse Transcriptase Inhibitors; Thionucleosides; Virus Replication	2000
Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks. Antiviral research, 2000, Volume: 45, Issue:1 Topics: 2-Aminopurine; Animals; Antiviral Agents; Carrier State; Disease Models, Animal; Drug Therapy, Combination; Famciclovir; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Lamivudine; Marmota; Prodrugs; Reverse Transcriptase Inhibitors; Viremia; Virus Replication	2000
HE2000 shows efficacy. AIDS patient care and STDs, 1999, Volume: 13, Issue:6 Topics: Animals; Anti-HIV Agents; Disease Models, Animal; Drugs, Investigational; Haplorhini; Lamivudine; Ritonavir; Simian Acquired Immunodeficiency Syndrome; Survival Analysis; Viral Load; Zidovudine	1999
Hepatitis B virus transgenic mice for the model of anti-hepatitis B virus drug study. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2001, Volume: 9, Issue:1 Topics: Animals; Antiviral Agents; Disease Models, Animal; Female; Hepatitis B; Hepatitis B virus; Lamivudine; Male; Mice; Mice, Transgenic; Thymosin; Vaccines, DNA	2001
[Experimental study on the effect of combination therapy with lamivudine and famciclovir against duck hepatitis B virus in vivo]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2001, Volume: 9, Issue:4 Topics: 2-Aminopurine; Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Drug Therapy, Combination; Ducks; Famciclovir; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Lamivudine; Microbial Sensitivity Tests	2001
Characterizing antiviral activity of adefovir dipivoxil in transgenic mice expressing hepatitis B virus. Antiviral research, 2002, Volume: 55, Issue:1 Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Hepatitis B; Hepatitis B virus; Lamivudine; Liver; Mice; Mice, Transgenic; Organophosphonates; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load	2002