Compounds > lamivudine
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lamivudine and Delayed Effects, Prenatal Exposure

lamivudine has been researched along with Delayed Effects, Prenatal Exposure in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's11 (57.89)29.6817
2010's5 (26.32)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Acosta, S; Balogun, K; Guzman Lenis, MS; Mount, HT; Sarkar, A; Serghides, L1
Divi, RL; Gibbons, AT; Liu, Y; Poirier, MC; Shide, ED; Shim Park, E; Woodward, RA1
Aldrovandi, GM; Chu, C; Foca, M; Ha, BF; Li, D; McIntosh, K; Meyer, WA; Moye, J; Rich, KC; Shearer, WT; Thompson, B; Walter, J1
Carter, MM; March, TH; McCash, CL; Poirier, MC; Seilkop, SK; Torres, SM; Walker, DM; Walker, VE1
Campen, MJ; Carter, MM; Chu, Y; Divi, RL; Einem, TL; Kang, H; McCash, CL; Poirier, MC; Seilkop, SK; Torres, SM; Walker, DM; Walker, VE1
Abrams, EJ; Adams, ME; Divi, RL; Nagashima, K; Nesel, CJ; O'Neill, JP; Poirier, MC; Seilkop, SK; Wade, NA; Walker, VE1
Abduch, R; Duarte, G; El Beitune, P; Figueiró-Filho, EA; Marcolin, AC; Quintana, SM1
Benhammou, V; Blanche, S; Rustin, P; Tardieu, M; Warszawski, J1
Abzug, MJ; Brady, M; Brogly, SB; Crain, MJ; Hughes, MD; Jean-Philippe, P; Mofenson, LM; Oleske, J; Seage, GR; Van Dyke, R; Ylitalo, N1
Chersich, MF; Urban, MF1
Barret, B; Blanche, S; Ciraru-Vigneron, N; Delfraissy, JF; Desguerre, I; Firtion, G; Lacroix, C; Mandelbrot, L; Mayaux, MJ; Rötig, A; Rouzioux, C; Rustin, P; Slama, A; Tardieu, M1
Belohradsky, BH; Rolinski, B; Stojanov, S; Wintergerst, U1
Alleva, E; Calamandrei, G; Valanzano, A; Venerosi, A2
Alleva, E; Ricceri, L; Sorace, A; Valanzano, A; Venerosi, A1
Fundarò, C; Genovese, O; Rendeli, C; Salvaggio, E; Tamburrini, E1

Reviews

1 review(s) available for lamivudine and Delayed Effects, Prenatal Exposure

ArticleYear
Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2004, Volume: 8, Issue:2

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Zidovudine

2004

Trials

1 trial(s) available for lamivudine and Delayed Effects, Prenatal Exposure

ArticleYear
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.
    AIDS (London, England), 2007, May-11, Volume: 21, Issue:8

    Topics: Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Reverse Transcriptase; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Maternal-Fetal Exchange; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Factors; Zidovudine

2007

Other Studies

17 other study(ies) available for lamivudine and Delayed Effects, Prenatal Exposure

ArticleYear
In utero exposure to protease inhibitor-based antiretroviral regimens delays growth and developmental milestones in mice.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Animals; Anti-HIV Agents; Atazanavir Sulfate; Developmental Disabilities; Dideoxynucleosides; Emtricitabine; Exploratory Behavior; Female; Fetal Growth Retardation; Growth Disorders; Hand Strength; HIV Protease Inhibitors; Homing Behavior; Lamivudine; Male; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Reflex, Abnormal; Reflex, Righting; Sensation Disorders; Taxis Response; Tenofovir

2020
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u
    National Toxicology Program genetically modified model report, 2013, Issue:16

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anti-HIV Agents; Body Weight; Chemistry, Pharmaceutical; Drug Combinations; Female; Haploinsufficiency; Intubation, Gastrointestinal; Lamivudine; Litter Size; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Nevirapine; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Reverse Transcriptase Inhibitors; Survival; Zidovudine

2013
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:7

    Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Dideoxynucleosides; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Gestational Age; Heart; Lamivudine; Mitochondria; Mitochondria, Heart; Oxygen Consumption; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2016
Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women.
    Pediatrics, 2009, Volume: 124, Issue:6

    Topics: Anti-HIV Agents; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Longitudinal Studies; Monocytes; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Reference Values; Reverse Transcriptase Inhibitors; Zidovudine

2009
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:1

    Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Echocardiography; Female; Fetus; Heart; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Microscopy, Electron, Transmission; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Characteristics; Zidovudine

2010
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:2

    Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Drug Therapy, Combination; Echocardiography; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Female; Heart; Lamivudine; Luminescent Measurements; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine

2010
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s
    National Toxicology Program technical report series, 2013, Issue:569

    Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia coli; Female; Lamivudine; Longevity; Male; Maternal Exposure; Mice; Mice, Inbred Strains; Nelfinavir; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Salmonella typhimurium; Skin Neoplasms; Zidovudine

2013
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir.
    AIDS (London, England), 2004, Apr-30, Volume: 18, Issue:7

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Umbilical Cord; Zidovudine

2004
Mitochondrial dysfunction following perinatal exposure to nucleoside analogues.
    AIDS (London, England), 2006, Aug-22, Volume: 20, Issue:13

    Topics: Anti-HIV Agents; Child; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Mitochondrial Diseases; Nervous System Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

2006
Dandy-Walker variant in an infant prenatally exposed to antiretroviral medication.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2007, Volume: 97, Issue:10

    Topics: Adult; Anti-Retroviral Agents; Dandy-Walker Syndrome; Female; Heart Ventricles; HIV Infections; Humans; Infant, Newborn; Lamivudine; Male; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Stavudine; Trimethoprim, Sulfamethoxazole Drug Combination

2007
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues.
    Lancet (London, England), 1999, Sep-25, Volume: 354, Issue:9184

    Topics: Acidosis, Lactic; Anti-HIV Agents; Child, Preschool; DNA, Mitochondrial; Female; France; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Mitochondrial Encephalomyopathies; Pregnancy; Prenatal Exposure Delayed Effects; Reference Values; Retrospective Studies; Zidovudine

1999
Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs.
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Mitochondria; Perinatal Care; Peroxisomes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine

2000
Effects of prenatal AZT+3TC treatment on open field behavior and responsiveness to scopolamine in adult mice.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:3

    Topics: Animals; Behavior, Animal; Female; Lamivudine; Male; Mice; Muscarinic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Scopolamine; Zidovudine

2000
Prenatal exposure to anti-HIV drugs: neurobehavioral effects of zidovudine (AZT) + lamivudine (3TC) treatment in mice.
    Teratology, 2001, Volume: 63, Issue:1

    Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Female; Gestational Age; Hand Strength; Homing Behavior; Lamivudine; Male; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Social Behavior; Zidovudine

2001
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
    Psychopharmacology, 2001, Volume: 153, Issue:4

    Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysiologic; Lamivudine; Male; Mice; Motor Activity; Muscimol; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Reaction Time; Time Factors; Zidovudine

2001
Neurological disorders after zidovudine exposure in utero.
    Prescrire international, 1999, Volume: 8, Issue:44

    Topics: Female; France; HIV Infections; Humans; Infant, Newborn; Lamivudine; Mitochondria; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; United States; Zidovudine

1999
Myelomeningocele in a child with intrauterine exposure to efavirenz.
    AIDS (London, England), 2002, Jan-25, Volume: 16, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Male; Maternal Exposure; Meningomyelocele; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Stavudine

2002