Page last updated: 2024-08-24

lamivudine and Aging

lamivudine has been researched along with Aging in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Alves Saldanha, S; Battegay, M; Buclin, T; Cavassini, M; Courlet, P; Decosterd, LA; Guidi, M; Marzolini, C; Stader, F; Stoeckle, M1
Chetty, M; De Sousa Mendes, M1
Bai, X; Hao, Y; Li, M; Lu, Z; Tang, Q; Wang, Y; Zhang, J; Zhang, Q; Zhao, J1
Arendt, G; Orhan, E; Schlonies, S; Stüve, O1
Adney, EM; Ambati, J; Ambati, K; Beauséjour, C; Boeke, JD; Brocculi, G; Caligiana, A; Criscione, SW; De Cecco, M; Elias, AE; Gorbunova, V; Helfand, SL; Ito, T; Le, O; Neretti, N; Petrashen, AP; Sedivy, JM; Seluanov, A; Simon, M; Skvir, NJ; Slagboom, PE1
Changchien, CS; Chen, CH; Hsu, MC; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Wang, JH; Yao, CC1
Capparelli, EV; Chokephaibulkit, K; Cressey, TR; McKinney, R; Mirochnick, M; Nikanjam, M; Tremoulet, AH1
Armishaw, J; Cameron, PU; Chuah, J; Cooper, DA; Crowe, SM; Fairley, C; Gouillou, M; Hearps, A; Koelsch, KK; Leeansyah, E; Lewin, SR; Liu, JP; Pierce, AB; Smit, de V; Solomon, A; Spelman, T; Tennakoon, S; Velayudham, P1
Choi, MH; Chung, YH; Jang, MK; Kim, JA; Lee, HC; Lee, YS; Park, NH; Ryu, SH; Shin, JW; Suh, DJ1
Chien, RN; Chu, CM; Liaw, YF; Tsai, SL; Yeh, CT1
Bergshoeff, AS; Burger, DM; de Groot, R; Gibb, DM; Green, H; Hartwig, NG; La Porte, CJ; Lyall, H; Rakhmanina, N; Soldin, S; Verweel, G; Verwey-Van Wissen, CP1

Trials

1 trial(s) available for lamivudine and Aging

ArticleYear
Developmental pharmacokinetic changes of Lamivudine in infants and children.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:12

    Topics: Adolescent; Age Factors; Aging; Anti-HIV Agents; Area Under Curve; Child; Child, Preschool; Creatinine; HIV Infections; Humans; Infant; Infant, Newborn; Lamivudine; Models, Biological; Reverse Transcriptase Inhibitors

2012

Other Studies

10 other study(ies) available for lamivudine and Aging

ArticleYear
Pharmacokinetic profiles of boosted darunavir, dolutegravir and lamivudine in aging people living with HIV.
    AIDS (London, England), 2020, 01-01, Volume: 34, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Anti-HIV Agents; Darunavir; Drug Therapy, Combination; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV Integrase Inhibitors; Humans; Lamivudine; Male; Middle Aged; Oxazines; Piperazines; Prospective Studies; Pyridones; Viral Load

2020
Are Standard Doses of Renally-Excreted Antiretrovirals in Older Patients Appropriate: A PBPK Study Comparing Exposures in the Elderly Population With Those in Renal Impairment.
    Drugs in R&D, 2019, Volume: 19, Issue:4

    Topics: Adult; Aged; Aging; Anti-HIV Agents; Area Under Curve; Dose-Response Relationship, Drug; Emtricitabine; Humans; Kidney Diseases; Kidney Function Tests; Lamivudine; Middle Aged; Models, Biological; Predictive Value of Tests; Tenofovir; Young Adult

2019
Lamivudine improves cognitive decline in SAMP8 mice: Integrating in vivo pharmacological evaluation and network pharmacology.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:17

    Topics: Aging; Animals; Cognition; Cognitive Dysfunction; Lamivudine; Male; Mice; Neurodegenerative Diseases; Reverse Transcriptase Inhibitors

2021
Simplification of combination antiretroviral therapy (cART) and the brain-a real-life experience.
    Journal of neurovirology, 2019, Volume: 25, Issue:2

    Topics: Adult; Aging; Antiretroviral Therapy, Highly Active; Brain; Cognition; Cognitive Dysfunction; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Retrospective Studies; Reverse Transcriptase Inhibitors; Severity of Illness Index; Tenofovir

2019
L1 drives IFN in senescent cells and promotes age-associated inflammation.
    Nature, 2019, Volume: 566, Issue:7742

    Topics: Aging; Animals; Cellular Senescence; Down-Regulation; Female; Fibroblasts; Humans; Inflammation; Interferon Type I; Lamivudine; Long Interspersed Nucleotide Elements; Male; Mice; Phenotype; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

2019
Combining age and HBsAg level predicts post-treatment durability of nucleos(t)ide analogue-induced HBeAg seroconversion.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:5

    Topics: Adult; Aging; Antiviral Agents; Consolidation Chemotherapy; Female; Follow-Up Studies; Forecasting; Hepatitis B; Hepatitis B e Antigens; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Nucleotides; Recurrence; Retrospective Studies; Risk; Seroconversion; Time Factors; Young Adult

2015
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
    The Journal of infectious diseases, 2013, Volume: 207, Issue:7

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine

2013
Long-term additional lamivudine therapy enhances durability of lamivudine-induced HBeAg loss: a prospective study.
    Journal of hepatology, 2003, Volume: 39, Issue:4

    Topics: Adult; Aging; DNA, Viral; Drug Administration Schedule; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Prognosis; Prospective Studies; Recurrence; Reverse Transcriptase Inhibitors; Risk Factors; Time Factors; Viral Core Proteins

2003
Determinants for sustained HBeAg response to lamivudine therapy.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:5

    Topics: Adult; Aging; Drug Administration Schedule; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Logistic Models; Male; Recurrence; Reverse Transcriptase Inhibitors; Treatment Outcome

2003
Age-dependent pharmacokinetics of lamivudine in HIV-infected children.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:4

    Topics: Aging; Algorithms; Anti-HIV Agents; Area Under Curve; Body Weight; Child; Child, Preschool; Female; HIV Infections; Humans; Lamivudine; Male; Sex Characteristics

2007