Compounds > lamivudine
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lamivudine and Acute Liver Injury, Drug-Induced

lamivudine has been researched along with Acute Liver Injury, Drug-Induced in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's8 (28.57)29.6817
2010's18 (64.29)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abongwa, LE; Bella, S; Charles, F; Domkam, I; Emmanuel, N; Eyongetah, M; Jude, B; Moungang, EC; Mua, FH; Ngum, V; Nyamache, AK; Okemo, P; Tamboh, TC; Torimiro, J1
Boricic, I; Dimitrijevic, B; Dragovic, G; Jevtovic, D; Nikolic, K; Salemovic, D; Tomanovic, N1
Bayisa, G; Bokore, A; Korme, B1
Iavarone, M; Maggioni, M; Merli, M; Orcese, C; Puoti, M; Rossotti, R1
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T1
Chen, L; Gao, J; Pan, L; Tang, W; Ye, X; Zhang, X; Zheng, R; Zheng, W1
Arastéh, K; Bergmann, F; Chaves, RL; Cooper, DA; Cordery, DV; Neto, JL; Robinson, P; Ruxrungtham, K; Scherer, J; Zajdenverg, R1
Burger, D; Chijoka, C; Chintu, C; Cook, A; Ferrier, A; Gibb, DM; Kabamba, D; Kalengo, C; Kankasa, C; Kityo, C; Mulenga, V; Thomason, M; Walker, AS1
Anwikar, SR; Bandekar, MS; Kshirsagar, NA; Pazare, AP; Smrati, B; Tatke, PA1
Dai, Z; Teng, Y; Wu, B; Xu, Y; Zhong, Y1
Chang, HM; Chen, YS; Lee, SS; Tsai, HC; Wann, SR1
Agbaji, O; Ekong, E; Graham, C; Hawkins, C; Idoko, J; Kanki, P; Meloni, S; Muazu, M; Murphy, R; Nimzing, L; Sankalé, JL; Thio, CL1
Maeda, Y; Okamoto, R; Sasaki, T1
Bouhour, D; Dumouchel-Champagne, H; Durupt, F; Ferry, T; Granier, P1
Azuaje, C; Domingo, P; Falco, V; Gatell, JM; Lopez, RM; Lopez-Colomes, JL; Mallolas, J; Ocaña, I; Pahissa, A; Pou, L; Ribera, E; Sambea, MA; Sánchez, P; Soriano, A1
Girault, V1
Choi, KH; Hong, SP; Hwang, SG; Kim, S; Ko, KH; Kwon, CI; Lee, JH; Oh, D; Park, PW; Rim, KS1
Asiimwe, F; Behumbiize, P; Brooks, JT; Forna, F; Liechty, CA; Mermin, J; Solberg, P; Tong, T; Weidle, PJ; Were, W1
Aoki, M; Genka, I; Kikuchi, Y; Oka, S; Tachikawa, N; Teruya, K; Yamaguchi, M; Yamamoto, Y; Yasuoka, A; Yasuoka, C1
Jurriaans, S; Lange, JM; Weel, J; Weverling, GJ; Wit, FW1

Reviews

5 review(s) available for lamivudine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Prophylactic Effect of Lamivudine for Chemotherapy-Induced Hepatitis B Reactivation in Breast Cancer: A Meta-Analysis.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Female; Hepatitis B; Humans; Lamivudine; Reverse Transcriptase Inhibitors

2015
Noncirrhotic portal hypertension associated with didanosine: a case report and literature review.
    Japanese journal of infectious diseases, 2012, Volume: 65, Issue:1

    Topics: Aged, 80 and over; Antiretroviral Therapy, Highly Active; Ascites; Chemical and Drug Induced Liver Injury; Didanosine; Fatal Outcome; HIV Infections; HIV-1; Humans; Hypertension, Portal; Lamivudine; Male; Nevirapine; Portal Vein; Thrombosis; Tomography, X-Ray Computed

2012
[Hepatotoxicity of chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:6

    Topics: Antineoplastic Agents; Antiviral Agents; Chemical and Drug Induced Liver Injury; Hematologic Neoplasms; Hepatitis B; Hepatitis C; Humans; Interferon-alpha; Lamivudine; Liver Diseases; Neoplasms; Reverse Transcriptase Inhibitors

2003
[The treatment of HIV infection].
    Presse medicale (Paris, France : 1983), 2005, Nov-19, Volume: 34, Issue:20 Pt 2

    Topics: Adenine; Anti-Retroviral Agents; Carbamates; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Sulfonamides; Tenofovir; Zidovudine

2005

Trials

3 trial(s) available for lamivudine and Acute Liver Injury, Drug-Induced

ArticleYear
Tipranavir/Ritonavir (500/200 mg and 500/100 mg) Was Virologically Non-Inferior to Lopinavir/Ritonavir (400/100 mg) at Week 48 in Treatment-Naïve HIV-1-Infected Patients: A Randomized, Multinational, Multicenter Trial.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Disease Progression; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Gastrointestinal Diseases; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Proportional Hazards Models; Pyridines; Pyrones; Ritonavir; Sulfonamides; Tenofovir; Young Adult

2016
Strategies for nevirapine initiation in HIV-infected children taking pediatric fixed-dose combination "baby pills" in Zambia: a randomized controlled trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Nov-01, Volume: 51, Issue:9

    Topics: Alanine Transaminase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Exanthema; HIV Infections; Humans; Lamivudine; Nevirapine; Stavudine; Zambia

2010
Once-daily regimen of saquinavir, ritonavir, didanosine, and lamivudine in HIV-infected patients with standard tuberculosis therapy (TBQD Study).
    Journal of acquired immune deficiency syndromes (1999), 2005, Nov-01, Volume: 40, Issue:3

    Topics: Adult; Anti-HIV Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Pilot Projects; Ritonavir; Saquinavir; Spain; Treatment Outcome; Tuberculosis

2005

Other Studies

20 other study(ies) available for lamivudine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon.
    BMC gastroenterology, 2022, Jun-03, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cameroon; Chemical and Drug Induced Liver Injury; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Risk Factors; Young Adult; Zidovudine

2022
Severe hepatotoxicity induced by efavirenz in a treatment-naïve, low body mass index HIV-infected, female patient with no hepatitis and other virus co-infections.
    Ultrastructural pathology, 2019, Volume: 43, Issue:4-5

    Topics: Adult; Alkynes; Benzoxazines; Body Mass Index; Chemical and Drug Induced Liver Injury; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors

2019
Determinants of anti-retroviral regimen changes among HIV/AIDS patients of east and west Wollega zone health institutions, Oromia region, west Ethiopia: a cross-sectional study.
    BMC pharmacology & toxicology, 2018, 06-05, Volume: 19, Issue:1

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Cross-Sectional Studies; Drug Substitution; Ethiopia; HIV Infections; Humans; Lamivudine; Nevirapine; Peripheral Nervous System Diseases; Retrospective Studies; Stavudine

2018
Severe cholestatic hepatitis related to abacavir/lamivudine/dolutegravir antiretroviral treatment in a HIV-1 infected subject.
    AIDS (London, England), 2018, 07-31, Volume: 32, Issue:12

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Cholestasis; Dideoxynucleosides; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Oxazines; Piperazines; Pyridones

2018
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine

2014
HAART induced adverse drug reactions: a retrospective analysis at a tertiary referral health care center in India.
    The International journal of risk & safety in medicine, 2011, Volume: 23, Issue:3

    Topics: Alkynes; Anemia; Antiretroviral Therapy, Highly Active; Benzoxazines; Chemical and Drug Induced Liver Injury; Cyclopropanes; Exanthema; Female; Gastritis; HIV Infections; Humans; India; Lamivudine; Male; Nevirapine; Peripheral Nervous System Diseases; Pharmacovigilance; Retrospective Studies; Severity of Illness Index; Sjogren's Syndrome; Stavudine

2011
Synthesis, stability and pharmacological evaluation of a novel codrug consisting of lamivudine and ursolic acid.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jan-23, Volume: 45, Issue:1-2

    Topics: Animals; Antiviral Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Stability; Ducks; Half-Life; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lamivudine; Lipase; Mice; Mice, Inbred ICR; Plasma; Prodrugs; Protective Agents; Random Allocation; Triterpenes; Ursolic Acid

2012
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria.
    Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2

    Topics: Adult; Alanine Transaminase; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Nevirapine; Nigeria; Organophosphorus Compounds; RNA, Viral; Stavudine; Zidovudine

2013
[Hypersensitive reaction to abacavir or syphilitic hepatitis?].
    Presse medicale (Paris, France : 1983), 2003, Oct-11, Volume: 32, Issue:33

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Ethylenediamines; HIV Seropositivity; Humans; Lamivudine; Male; Syphilis; Zidovudine

2003
[Hepatitis B and C virus infection and liver dysfunction in patients receiving chemotherapy].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2006, Volume: 48, Issue:6

    Topics: Adult; Antineoplastic Agents; Antiviral Agents; Chemical and Drug Induced Liver Injury; Female; Hepatitis B; Hepatitis C; Humans; Lamivudine; Liver Diseases; Male; Middle Aged; Neoplasms; Prevalence

2006
Clinical toxicity of highly active antiretroviral therapy in a home-based AIDS care program in rural Uganda.
    Journal of acquired immune deficiency syndromes (1999), 2007, Apr-01, Volume: 44, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cyclopropanes; Exanthema; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Nevirapine; Pancreatitis; Peripheral Nervous System Diseases; Proportional Hazards Models; Rural Health; Stavudine; Survival Analysis; Uganda

2007
Mitigation of hepato-cellular injury caused by HAART with glycyrrhizin compound in patients co-infected with HIV and HCV.
    Japanese journal of infectious diseases, 1999, Volume: 52, Issue:6

    Topics: Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Combinations; Drug Therapy, Combination; Glycine; Glycyrrhetinic Acid; Hemophilia A; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zalcitabine; Zidovudine

1999
Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures--worldwide, 1997-2000.
    MMWR. Morbidity and mortality weekly report, 2001, Jan-05, Volume: 49, Issue:51-52

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infections; Humans; Lamivudine; Liver Failure; Male; Nevirapine; Occupational Exposure; Reverse Transcriptase Inhibitors; Rhabdomyolysis; Zidovudine

2001
Incidence of and risk factors for severe hepatotoxicity associated with antiretroviral combination therapy.
    The Journal of infectious diseases, 2002, Jul-01, Volume: 186, Issue:1

    Topics: Adult; Alanine Transaminase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Hepatitis B; Hepatitis C; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Liver Function Tests; Male; Nevirapine; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; Sex Factors; Transaminases

2002