lactulose has been researched along with Disease Models, Animal in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.94) | 18.7374 |
| 1990's | 9 (26.47) | 18.2507 |
| 2000's | 9 (26.47) | 29.6817 |
| 2010's | 12 (35.29) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Hu, G; Liu, S; Yang, Z; Yi, R; Zeng, H; Zhao, X | 1 |
| Chang, CH; Hsieh-Li, HM; Huang, HJ; Lai, DM; Lee, GC; Lee, YS; Lee-Chen, GJ | 1 |
| Heguy, A; Ruggles, KV; Tetz, GV; Tetz, V; Tsirigos, A; Zhou, H | 1 |
| Céspedes, IC; de Andrade, JS; de Barros Viana, M; Le Sueur-Maluf, L; Mariotti, FFN; Mendes, NF; Nagaoka, MR | 1 |
| Chung, HJ; Hong, ST; Kim, HJ; Liu, J; Lkhagva, E | 1 |
| Fukunaga, M; Hirata, S; Kadowaki, D; Mei, M; Murase, T; Nakajima, A; Narita, Y; Sueyoshi, M; Tanaka, G | 1 |
| Chen, XW; Fu, AX; Peng, SN; Zeng, HH; Zhu, QX | 1 |
| Algieri, F; Cardelle-Cobas, A; Corzo, N; Galvez, J; Garrido-Mesa, J; Garrido-Mesa, N; Guerra-Hernández, E; Montilla, A; Olano, A; Rodriguez-Cabezas, ME; Rodríguez-Nogales, A; Utrilla, MP; Vezza, T; Zarzuelo, A | 1 |
| Chen, CM; Chen, WL; Hsieh-Li, HM; Hsu, KC; Huang, SH; Huang, YJ; Kung, PJ; Lee, GC; Lee-Chen, GJ; Lin, CH; Lin, JY; Tao, YC; Wang, CM; Wu, YR; Yang, JM | 1 |
| Halpin, LE; Northrop, NA; Yamamoto, BK | 1 |
| Demetter, P; Devière, J; Goffin, P; Gustot, T; Hols, P; Moreno, C; Nicaise, C; Prozzi, D; Quertinmont, E; Suain, V; Viaene, E | 1 |
| Fan, Y; Jin, J; Su, Y; Wu, S; Zhang, Z | 1 |
| Cananzi, M; De Coppi, P; Eaton, S; Ghionzoli, M; Lauriti, G; Pierro, A; Smith, VV; Zani, A | 1 |
| Huang, XF; Li, YM; Liu, QQ; Nie, QH; Wang, AH; Yang, J | 1 |
| Arlt, A; Bewig, B; Ellrichmann, M; Hampe, J; Häsler, R; Kruse, ML; Lange-Grumfeld, J; Noth, R; Rosenstiel, P; Schreiber, S; Stüber, E | 1 |
| Halpin, LE; Yamamoto, BK | 1 |
| Kato, S; Mózsik, G; Okayama, M; Rumi, G; Takeuchi, K; Tsubouchi, R | 1 |
| Fazal, N; Gamelli, RL; Goto, M; Goyal, A; Holloway, VM; Ravindranath, TM; Samonte, VA; Sayeed, MM | 1 |
| Camuesco, D; Comalada, M; Concha, A; Di Stasi, LC; Galvez, J; Nieto, A; Peran, L; Rodriguez-Cabezas, ME; Zarzuelo, A | 1 |
| Fan, JG; Wang, GL; Xu, ZJ | 1 |
| Peng, JS; Yin, Y; Zhan, WH; Zhao, XL; Zhao, ZG | 1 |
| Coran, AG; Lurie, M; Mogilner, JG; Shaoul, R; Srugo, I; Sukhotnik, I | 1 |
| Batavier, P; de Groot, GH; Maas, HC; Schalm, SW; Schicht, I | 1 |
| Hirata, Y; Kimura, K; Ozaki, T; Sato, S; Suzuki, K; Watanabe, M; Yoshikuni, Y | 1 |
| Hirata, Y; Kimura, K; Niida, H; Ozaki, T; Ueda, F; Watanabe, M; Yamamoto, O; Yoshikuni, Y | 1 |
| Hirata, Y; Kimura, K; Mushiroi, T; Ozaki, T; Shibahara, R; Ukai, Y; Watanabe, M | 1 |
| Hirata, Y; Kimura, K; Ozaki, T; Watanabe, M; Yoshikuni, Y | 1 |
| Fink, MP | 1 |
| Bengisun, S; Karayalçin, K; Kesenci, M; Ozaslan, C; Törüner, A; Türkçapar, AG; Yerdel, MA | 1 |
| Arndt, H; Palitzsch, KD; Schölmerich, J | 1 |
| Kien, CL; Marcon, M; Murray, RD; Qualman, SJ | 1 |
| Martin, GR; Poole, A; Sigalet, DL | 1 |
| Bertolo, C; Colombo, L; Mussini, E; Zuccato, E | 1 |
1 review(s) available for lactulose and Disease Models, Animal
| Article | Year |
|---|---|
The Pharmabiotic Approach to Treat Hyperammonemia.
Topics: Ammonia; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Models, Animal; Gastrointestinal Agents; Gastrointestinal Microbiome; Humans; Hyperammonemia; Lactulose; Liver; Probiotics; Randomized Controlled Trials as Topic; Synbiotics | 2018 |
33 other study(ies) available for lactulose and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Prevention of dextran sulfate sodium (DSS)-induced ulcerative colitis in mice by a synbiotic approach using probiotic and lactulose.
Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Lactulose; Mice; Mice, Inbred C57BL; NF-kappa B; Probiotics; Synbiotics | 2023 |
Prebiotic Lactulose Ameliorates the Cognitive Deficit in Alzheimer's Disease Mouse Model through Macroautophagy and Chaperone-Mediated Autophagy Pathways.
Topics: Alzheimer Disease; Animals; Autophagy; Chaperone-Mediated Autophagy; Cognition; Disease Models, Animal; Lactulose; Macroautophagy; Mice; Neuroprotective Agents; Prebiotics | 2021 |
Bacteriophages as potential new mammalian pathogens.
Topics: Animals; Bacterial Translocation; Bacteriophages; Blood Chemical Analysis; Cytokines; Disease Models, Animal; Endotoxins; Gastrointestinal Microbiome; Gastrointestinal Tract; Lactulose; Mannitol; Rats | 2017 |
Lactulose decreases neuronal activation and attenuates motor behavioral deficits in hyperammonemic rats.
Topics: Ammonia; Animals; Aquaporin 4; Aspartate Aminotransferases; Behavior, Animal; Bilirubin; Creatinine; Disease Models, Animal; Hyperammonemia; Lactulose; Liver; Male; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar | 2017 |
Effects of lactulose on renal function and gut microbiota in adenine-induced chronic kidney disease rats.
Topics: Adenine; Animals; Bacteria; Biomarkers; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Disease Progression; Fibrosis; Gastrointestinal Microbiome; Kidney; Lactulose; Male; Oxidative Stress; Prebiotics; Rats, Wistar; Renal Insufficiency, Chronic; Uremia | 2019 |
Effects of rhein on intestinal epithelial tight junction in IgA nephropathy.
Topics: Animals; Anthraquinones; Disease Models, Animal; Epithelial Cells; Female; Glomerulonephritis, IGA; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Lactulose; Mannose; Occludin; Permeability; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tight Junctions; Time Factors; Zonula Occludens-1 Protein | 2013 |
Intestinal anti-inflammatory effects of oligosaccharides derived from lactulose in the trinitrobenzenesulfonic acid model of rat colitis.
Topics: Animals; Anti-Inflammatory Agents; Chemokines; Colitis; Disease Models, Animal; Female; Humans; Interleukins; Intestines; Lactulose; Microbiota; Oligosaccharides; Prebiotics; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2014 |
The potential of lactulose and melibiose, two novel trehalase-indigestible and autophagy-inducing disaccharides, for polyQ-mediated neurodegenerative disease treatment.
Topics: Animals; Autophagy; Cell Line; Computer-Aided Design; Digestion; Disease Models, Animal; Drug Design; Drug Stability; Hydrogen Bonding; Hydrolysis; Lactulose; Melibiose; Mice, Transgenic; Molecular Docking Simulation; Molecular Structure; Neurodegenerative Diseases; Neuroprotective Agents; Peptides; Protein Aggregates; Purkinje Cells; Structure-Activity Relationship; TATA-Box Binding Protein; Time Factors; Transfection; Trehalase; Trehalose | 2015 |
Peripheral ammonia and blood brain barrier structure and function after methamphetamine.
Topics: Ammonia; Animals; Blood-Brain Barrier; Capillaries; Capillary Permeability; Central Nervous System Stimulants; Cerebral Cortex; Claudin-5; Disease Models, Animal; Fever; Gastrointestinal Agents; Lactulose; Male; Matrix Metalloproteinase 9; Methamphetamine; Occludin; Rats, Sprague-Dawley | 2016 |
Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents.
Topics: Acute Disease; Alanine; Ammonia; Animals; Carbon Tetrachloride; Chronic Disease; Disease Models, Animal; Hyperammonemia; Lactobacillus plantarum; Lactulose; Liver Failure; Male; Mice; Mice, Inbred C57BL; Probiotics; Rats; Rats, Inbred Lew; Thioacetamide | 2008 |
The preliminary experimental and clinical study of the relationship between the pigment gallstone and intestinal mucosal barrier.
Topics: Amine Oxidase (Copper-Containing); Animals; Bacterial Translocation; Bile; Bile Pigments; Case-Control Studies; Cholesterol; Disease Models, Animal; Endotoxins; Female; Gallstones; Glucuronidase; Glutamine; Guinea Pigs; Humans; Intestinal Mucosa; Lactulose; Lymph Nodes; Male; Mannitol; Permeability; Pilot Projects; Radiopharmaceuticals; Technetium Tc 99m Pentetate | 2009 |
Does intestinal permeability lead to organ failure in experimental necrotizing enterocolitis?
Topics: Animals; Animals, Newborn; Cell Membrane Permeability; Disease Models, Animal; Enterocolitis, Necrotizing; Female; Follow-Up Studies; Gas Chromatography-Mass Spectrometry; Intestinal Mucosa; Lactulose; Mannitol; Multiple Organ Failure; Pregnancy; Rats; Rats, Sprague-Dawley | 2010 |
Effects of intestinal intervention on bacterial translocation in a rat model of acute liver failure in vivo.
Topics: Animals; Bacterial Translocation; Bentonite; Cytokines; Disease Models, Animal; Electrophoresis, Agar Gel; Endotoxins; Escherichia coli; Flow Cytometry; Galactosamine; Gastrointestinal Agents; Green Fluorescent Proteins; Intestines; Lactulose; Liver; Liver Failure, Acute; Lymph Nodes; Male; Microscopy, Confocal; Rats; Rats, Sprague-Dawley; Silicates; Spleen; Toll-Like Receptor 4 | 2010 |
Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model.
Topics: Animals; Disease Models, Animal; Down-Regulation; Graft vs Host Disease; Immunohistochemistry; Jejunum; Lactulose; Mannitol; Membrane Proteins; Mice; Mice, Inbred C57BL; Microscopy, Electron; Microscopy, Fluorescence; Occludin; Permeability; Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Peripheral ammonia as a mediator of methamphetamine neurotoxicity.
Topics: Alanine Transaminase; Ammonia; Analysis of Variance; Animals; Aspartate Aminotransferases; Benzodiazepines; Biogenic Monoamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Fever; Gene Expression Regulation; Lactulose; Liver Diseases; Male; Mass Spectrometry; Methamphetamine; Microdialysis; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Protective effect of lactulose on dextran sulfate sodium-induced colonic inflammation in rats.
Topics: Animals; Biopsy, Needle; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation Mediators; Intestinal Mucosa; Lactulose; Lipid Peroxidation; Male; Peroxidase; Probability; Protective Agents; Rats; Rats, Wistar; Risk Factors; Sensitivity and Specificity | 2004 |
Exacerbation of intestinal permeability in rats after a two-hit injury: burn and Enterococcus faecalis infection.
Topics: Animals; Bacterial Translocation; Burns; Capillary Permeability; Carbon Radioisotopes; Chemotaxis, Leukocyte; Claudin-3; Disease Models, Animal; Enterococcus faecalis; Gram-Positive Bacterial Infections; Ileum; Immunoblotting; Immunohistochemistry; Injections; Intestinal Mucosa; Lactulose; Male; Mannitol; Membrane Proteins; Neutrophil Infiltration; Occludin; Rats; Rats, Sprague-Dawley; Tight Junctions; Time Factors | 2004 |
Preventative effects of lactulose in the trinitrobenzenesulphonic acid model of rat colitis.
Topics: Animals; Colitis; Disease Models, Animal; Female; Gastrointestinal Agents; Lactobacillaceae; Lactulose; Leukotriene B4; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2005 |
Effect of lactulose on establishment of a rat non-alcoholic steatohepatitis model.
Topics: Animals; Disease Models, Animal; Fatty Liver; Gastrointestinal Agents; Hepatitis; Lactulose; Male; Rats; Rats, Sprague-Dawley | 2005 |
[Effect of ecoimmunonutrition on gut barrier function in rats with systemic inflammatory response syndrome].
Topics: Animals; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Mucosa; Lactulose; Male; Rats; Rats, Sprague-Dawley; Systemic Inflammatory Response Syndrome | 2005 |
Effect of lactulose on bacterial translocation and intestinal adaptation in a rat model of short bowel syndrome.
Topics: Adaptation, Physiological; Administration, Oral; Animals; Bacterial Translocation; Disease Models, Animal; Intestinal Mucosa; Intestine, Small; Lactulose; Male; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome; Treatment Outcome | 2008 |
Incidence of endotoxemia in pigs with ischemic hepatic necrosis treated by hemodialysis. Prevention of endotoxemia with lactulose.
Topics: Animals; Disaccharides; Disease Models, Animal; Endotoxins; Enema; Ischemia; Lactulose; Liver; Liver Diseases; Necrosis; Renal Dialysis; Sepsis; Swine | 1983 |
[The effect of lactitol (NS-4) on the concentrations of ammonia and amino acids in blood and cerebrospinal fluid in Eck fistula (portacaval-shunted) dogs].
Topics: Amino Acids; Ammonia; Animals; Disease Models, Animal; Dogs; Hepatic Encephalopathy; Lactulose; Male; Portacaval Shunt, Surgical; Sugar Alcohols | 1995 |
Mechanism for lowering blood ammonia levels by lactitol.
Topics: Acetates; Administration, Oral; Ammonia; Animals; Cecum; Charcoal; Colon; Disease Models, Animal; Gastrointestinal Transit; Hydrogen-Ion Concentration; Intestinal Absorption; Intestine, Small; Lactulose; Male; Portal Vein; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sugar Alcohols | 1995 |
[Lactitol suppresses the disturbance of consciousness caused by experimentally induced hepatic encephalopathy in rats: an EEG study].
Topics: Animals; Consciousness Disorders; Disease Models, Animal; Electroencephalography; Hepatic Encephalopathy; Humans; Lactulose; Rats; Rats, Wistar; Sugar Alcohols | 1995 |
[Effect of lactitol (NS-4) on the increase in blood and brain ammonia concentration and on coma in newly developed rat models of hepatic coma].
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Hepatic Encephalopathy; Lactulose; Male; Rats; Rats, Sprague-Dawley; Sugar Alcohols | 1995 |
Interpreting dual-sugar absorption studies in critically ill patients: what are the implications of apparent increases in intestinal permeability to hydrophilic solutes?
Topics: Animals; Bacterial Translocation; Carbohydrates; Critical Illness; Disease Models, Animal; Dopamine; Humans; Infections; Intestinal Absorption; Intestinal Mucosa; Lactulose; Permeability; Rhamnose; Species Specificity | 1997 |
Effect of lactulose on bacterial translocation.
Topics: Animals; Bacterial Translocation; Cholestasis; Disease Models, Animal; Gastrointestinal Agents; Lactulose; Lymphatic System; Male; Rats; Rats, Wistar | 1997 |
Lactulose and neomycin attenuate leukocyte-endothelial cell adhesion in an animal model of inflammatory bowel disease.
Topics: Animals; Anti-Bacterial Agents; Cell Adhesion; Cell Communication; Disease Models, Animal; Endothelium; Gastrointestinal Agents; Ileitis; Ileum; Indomethacin; Inflammation; Inflammatory Bowel Diseases; Lactulose; Leukocytes; Male; Microcirculation; Neomycin; Rats; Rats, Sprague-Dawley | 1998 |
Lactulose feeding in piglets: a model for persistent diarrhea and colitis induced by severe sugar malabsorption.
Topics: Animals; Animals, Newborn; Apoptosis; Carbohydrate Metabolism; Cell Division; Colitis; Diarrhea; Disease Models, Animal; Fermentation; Intestinal Mucosa; Lactulose; Malabsorption Syndromes; Rats; Swine | 1999 |
Differential sugar absorption as a marker for adaptation in short bowel syndrome.
Topics: Absorption; Adaptation, Physiological; Animals; Biomarkers; Disease Models, Animal; Intestinal Mucosa; Lactulose; Male; Mannitol; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Short Bowel Syndrome | 2000 |
Indomethacin-induced enteropathy: effect of the drug regimen on intestinal permeability in rats.
Topics: Administration, Oral; Animals; Chromatography, Gas; Disease Models, Animal; Indomethacin; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestine, Small; Lactulose; Male; Mannitol; Permeability; Rats; Rats, Sprague-Dawley | 1992 |