lactoferrin and Cataract

Cataract is an eye disease of major human concern and its prevention is important to control the global incidences of blindness. The emergence of cataract in the eye lens by strong UV radiation and growing pollution could be effectively reduced by natural antioxidant biomolecules such as flavonoids, phenolic acids, carotenoids and vitamins. This goal can be achieved either by direct external use of antioxidant biomolecules in the form of topical application as an eye drops, food supplements or through nanobiotechnology based formulation without any side effects. In this manuscript, we have discussed the mechanisms of cataract formation and the preventive role of different classes of natural antioxidant biomolecules. Further, role of nanobiotechnology to enhance therapeutic potential of these natural antioxidant molecules by enhancing solubility, stability, bioavailability and sustained release has been briefly discussed.

Topics: Antioxidants; Cataract; Crystallins; Flavonoids; Humans; Hydroxybenzoates; Lactoferrin; Medicine, Ayurvedic; Nanomedicine; Nanotechnology; Osmotic Pressure; Oxidation-Reduction; Phase Transition; Protein Conformation; Vitamins

The paper's aim is to evidence the quantitative and qualitative modifications of the tear film before and after operation, in accordance with the presents of the pseudoexfoliative syndrome at the cataract operated patients.

Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Electrophoresis, Polyacrylamide Gel; Exfoliation Syndrome; Female; Humans; Immunoglobulin A; Lacrimal Apparatus; Lactoferrin; Male; Middle Aged; Prospective Studies; Surface Tension; Tears