lactic acid has been researched along with Uremia in 27 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "End-stage renal disease (ESRD) is associated with uremia and increased systemic inflammation." | 1.43 | Intestinal microbiota in pediatric patients with end stage renal disease: a Midwest Pediatric Nephrology Consortium study. ( Aviles, DH; Blanchard, EE; Crespo-Salgado, J; Ferris, M; Greenbaum, LA; Kallash, M; Stewart, T; Taylor, CM; Vehaskari, VM; Wang, G; Zhang, Q, 2016) |
| "The metabolic disorders related to acute renal failure or associated with it, such as liver failure, may affect lactate metabolism, and therefore they are often regarded as limiting factors for the use of lactate-containing fluids in such patients." | 1.33 | Lactate metabolism in acute uremia. ( Ichai, C; Krouzecky, A; Leverve, X; Matejovic, M; Mustafa, I; Novak, I; Rokyta, R, 2005) |
| "7." | 1.29 | Metabolic acidosis is a potent stimulus for cellular inorganic phosphate generation in uraemia. ( Baker, FE; Bevington, A; Brough, D; Hattersley, J; Walls, J, 1995) |
| "Glycogen synthesis was subnormal at all levels of insulin and at the maximal insulin concentration; it was 54% lower in muscles of ARF compared to control rats." | 1.27 | Specific defects in insulin-mediated muscle metabolism in acute uremia. ( Clark, AS; Goheer, MA; May, RC; Mitch, WE, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 10 (37.04) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vila Cuenca, M | 1 |
| Keuning, ED | 1 |
| Talhout, W | 1 |
| Paauw, NJ | 1 |
| van Ittersum, FJ | 1 |
| Ter Wee, PM | 1 |
| Beelen, RHJ | 1 |
| Vervloet, MG | 1 |
| Ferrantelli, E | 1 |
| Weigand, KM | 1 |
| Schirris, TJJ | 1 |
| Houweling, M | 1 |
| van den Heuvel, JJMW | 1 |
| Koenderink, JB | 1 |
| Dankers, ACA | 1 |
| Russel, FGM | 1 |
| Greupink, R | 1 |
| Crespo-Salgado, J | 1 |
| Vehaskari, VM | 1 |
| Stewart, T | 1 |
| Ferris, M | 1 |
| Zhang, Q | 1 |
| Wang, G | 1 |
| Blanchard, EE | 1 |
| Taylor, CM | 1 |
| Kallash, M | 1 |
| Greenbaum, LA | 1 |
| Aviles, DH | 1 |
| GALLOWAY, RE | 1 |
| MORGAN, JM | 1 |
| Leverve, X | 1 |
| Mustafa, I | 1 |
| Novak, I | 1 |
| Krouzecky, A | 1 |
| Rokyta, R | 1 |
| Matejovic, M | 1 |
| Ichai, C | 1 |
| Grzegorzewska, AE | 1 |
| Delmez, JA | 1 |
| Rutherford, WE | 1 |
| Klahr, S | 1 |
| Blondin, J | 1 |
| Kreusser, W | 1 |
| Rambausek, M | 1 |
| Klooker, P | 1 |
| Brückner, U | 1 |
| Ritz, E | 1 |
| Madias, NE | 1 |
| Homer, SM | 1 |
| Johns, CA | 1 |
| Cohen, JJ | 1 |
| Bazzato, G | 1 |
| Coli, U | 1 |
| Landini, S | 1 |
| Fracasso, A | 1 |
| Morachiello, P | 1 |
| Righetto, F | 1 |
| Scanferla, F | 1 |
| Onesti, G | 1 |
| Bevington, A | 1 |
| Brough, D | 1 |
| Baker, FE | 1 |
| Hattersley, J | 1 |
| Walls, J | 1 |
| Panichi, V | 1 |
| Parrini, M | 1 |
| Bianchi, AM | 1 |
| Andreini, B | 1 |
| Cirami, C | 1 |
| Finato, V | 1 |
| Palla, R | 1 |
| Domingo, JL | 1 |
| Gomez, M | 1 |
| Llobet, JM | 1 |
| del Castillo, D | 1 |
| Corbella, J | 1 |
| Thompson, CH | 1 |
| Kemp, GJ | 1 |
| Taylor, DJ | 1 |
| Ledingham, JG | 1 |
| Radda, GK | 1 |
| Rajagopalan, B | 1 |
| Böhler, J | 2 |
| Dobos, GJ | 1 |
| Burger, M | 1 |
| Kuhlmann, J | 1 |
| Passlick-Deetjen, J | 1 |
| Schollmeyer, P | 1 |
| Hirayama, A | 2 |
| Noronha-Dutra, AA | 2 |
| Gordge, MP | 2 |
| Neild, GH | 2 |
| Hothersall, JS | 2 |
| Lindgren, L | 1 |
| Tikkanen, I | 1 |
| Reissell, E | 1 |
| Kirvelä, M | 1 |
| Orko, R | 1 |
| Salmela, K | 1 |
| Ahonen, J | 1 |
| Cianciaruso, B | 1 |
| Bellizzi, V | 1 |
| Napoli, R | 1 |
| Saccá, L | 1 |
| Kopple, JD | 1 |
| Ittel, TH | 1 |
| Griessner, A | 1 |
| Sieberth, HG | 1 |
| Tomson, CR | 1 |
| Channon, SM | 1 |
| Ward, MK | 1 |
| Laker, MF | 1 |
| Biasioli, S | 1 |
| Feriani, M | 1 |
| Chiaramonte, S | 1 |
| La Greca, G | 1 |
| Roullet, JB | 2 |
| Lacour, B | 2 |
| Yvert, JP | 2 |
| Drueke, T | 2 |
| Prat, JJ | 1 |
| May, RC | 1 |
| Clark, AS | 1 |
| Goheer, MA | 1 |
| Mitch, WE | 1 |
| Riegel, W | 1 |
| Hörl, WH | 1 |
2 reviews available for lactic acid and Uremia
| Article | Year |
|---|---|
Protecting the peritoneal membrane in dialyzed patients.
Topics: Dialysis Solutions; Glucose; Humans; Lactic Acid; Peritoneal Dialysis; Peritoneum; Randomized Contro | 2006 |
Treatment of acute renal failure in intensive care patients.
Topics: Acidosis; Acute Kidney Injury; Bicarbonates; Hemofiltration; Humans; Intensive Care Units; Lactates; | 1996 |
1 trial available for lactic acid and Uremia
| Article | Year |
|---|---|
Mechanisms of acid-base homeostasis in acetate and bicarbonate dialysis, lactate hemofiltration and hemodiafiltration.
Topics: 2,3-Diphosphoglycerate; Acetates; Acid-Base Equilibrium; Adenosine Diphosphate; Analysis of Variance | 1994 |
24 other studies available for lactic acid and Uremia
| Article | Year |
|---|---|
Differences in peritoneal response after exposure to low-GDP bicarbonate/lactate-buffered dialysis solution compared to conventional dialysis solution in a uremic mouse model.
Topics: Actins; Animals; Bicarbonates; Buffers; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chemokine | 2018 |
Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity.
Topics: Adenosine Triphosphate; HEK293 Cells; Hepatocytes; Humans; Lactic Acid; Membrane Transport Proteins; | 2019 |
Intestinal microbiota in pediatric patients with end stage renal disease: a Midwest Pediatric Nephrology Consortium study.
Topics: Actinobacteria; Adolescent; Bacterial Load; Bacteroidetes; C-Reactive Protein; Child; Child, Prescho | 2016 |
SERUM PYRUVATE AND LACTATE IN UREMIA.
Topics: Blood Chemical Analysis; Coenzyme A; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Uremia | 1964 |
Lactate metabolism in acute uremia.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Energy Metabolism; Glucose; Hemodynamics; Homeostasis; | 2005 |
Studies on the role of the liver and splanchnic tissues in the production of carbohydrate intolerance in uremia.
Topics: Alanine; Animals; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Humans; Kinetics; | 1981 |
Stimulation of cardiac contractility by catecholamines is diminished in experimental uremia.
Topics: Angiotensin II; Animals; Catecholamines; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Hemo | 1984 |
Hypochloremia as a consequence of anion gap metabolic acidosis.
Topics: Acidosis; Animals; Bicarbonates; Chlorides; Lactates; Lactic Acid; Male; Potassium; Rats; Rats, Inbr | 1984 |
Xylitol as osmotic agent in CAPD: an alternative to glucose for uremic diabetic patients?
Topics: Adult; Diabetic Nephropathies; Female; Humans; Insulin; Lactates; Lactic Acid; Lipids; Male; Middle | 1982 |
Metabolic acidosis is a potent stimulus for cellular inorganic phosphate generation in uraemia.
Topics: Acidosis; Cells, Cultured; Erythrocytes; Female; Humans; Hydrochloric Acid; Hydrogen-Ion Concentrati | 1995 |
Influence of citric, ascorbic and lactic acids on the gastrointestinal absorption of aluminum in uremic rats.
Topics: Acids; Aluminum; Animals; Ascorbic Acid; Citrates; Citric Acid; Diet; Intestinal Absorption; Lactate | 1994 |
Effect of chronic uraemia on skeletal muscle metabolism in man.
Topics: Adenosine Triphosphate; Aged; Anemia; Chronic Disease; Energy Metabolism; Exercise; Humans; Hydrogen | 1993 |
Improved cytosolic free calcium mobilization and superoxide production in bicarbonate-based peritoneal dialysis solution.
Topics: Bicarbonates; Calcium; Cytosol; Dialysis Solutions; Glucose; Humans; Hydrogen-Ion Concentration; In | 1997 |
Inhibition of neutrophil superoxide production by uremic concentrations of guanidino compounds.
Topics: Adenosine Triphosphate; Cell Adhesion; Dose-Response Relationship, Drug; Energy Metabolism; Guanidin | 2000 |
Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production.
Topics: Adenosine Triphosphate; Energy Metabolism; Guanidines; Humans; In Vitro Techniques; Lactic Acid; Neu | 2001 |
Alpha-human-ANP response to preanesthetic volume expansion and subsequent renal transplantation in diabetic and nondiabetic uremic patients.
Topics: Adult; Atrial Natriuretic Factor; Blood Volume; Diabetic Nephropathies; Female; Humans; Kidney Trans | 1992 |
Hepatic uptake and release of glucose, lactate, and amino acids in acutely uremic dogs.
Topics: Acute Disease; Amino Acids; Animals; Blood Glucose; Dogs; Femoral Artery; Glucose; Insulin; Lactates | 1991 |
Effect of lactate on the absorption and retention of aluminum in the remnant kidney rat model.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Intestinal Absorption; Kidney; | 1991 |
Ascorbate-induced hyperoxalaemia has no significant effect on lactate generation or erythrocyte 2,3,diphosphoglycerate in dialysis patients.
Topics: 2,3-Diphosphoglycerate; Adult; Ascorbic Acid; Diphosphoglyceric Acids; Erythrocytes; Forearm; Humans | 1990 |
Buffers in peritoneal dialysis.
Topics: Acetates; Acetic Acid; Acid-Base Equilibrium; Bicarbonates; Buffers; Humans; Lactates; Lactic Acid; | 1987 |
Correction by insulin of disturbed TG-rich LP metabolism in rats with chronic renal failure.
Topics: Adipose Tissue; Animals; Apolipoproteins; Blood Glucose; Cholesterol; Cholesterol, VLDL; Fatty Acids | 1986 |
Factors of increase in serum triglyceride-rich lipoproteins in uremic rats.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Blood Glucose; Energy Metabolism; Epididymis; Fastin | 1985 |
Specific defects in insulin-mediated muscle metabolism in acute uremia.
Topics: Animals; Biological Transport, Active; Glucose; Glycogen; Insulin; Insulin Resistance; Lactates; Lac | 1985 |
Role of energy charge and redox state for hepatocyte gluconeogenesis of acutely uremic rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Energy Metabolism; Female; Gluconeogenesis; Hydroxybu | 1985 |