lactic acid has been researched along with Transposition of Great Vessels in 6 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Transposition of Great Vessels: A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mean choline levels were higher in CHD compared with controls (CHD 2." | 1.91 | Magnetic Resonance Spectroscopy of Brain Metabolism in Fetuses With Congenital Heart Disease. ( Andescavage, NN; Cheng, JJ; Donofrio, MT; du Plessis, AJ; Gimovsky, AC; Kapse, K; Limperopoulos, C; Pradhan, S; Sharker, Y; Wessel, D, 2023) |
| "Levosimendan is a calcium-sensitizing agent with effective inotropic properties." | 1.35 | First experiences with intraoperative Levosimendan in pediatric cardiac surgery. ( Boethig, D; Goerler, H; Huber, D; Osthaus, WA; Sasse, M; Sümpelmann, R; Winterhalter, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Andescavage, NN | 1 |
| Pradhan, S | 1 |
| Gimovsky, AC | 1 |
| Kapse, K | 1 |
| Donofrio, MT | 1 |
| Cheng, JJ | 1 |
| Sharker, Y | 1 |
| Wessel, D | 1 |
| du Plessis, AJ | 1 |
| Limperopoulos, C | 1 |
| Chasovskyi, K | 1 |
| Zhovnir, V | 1 |
| Vorobiova, G | 1 |
| Yemets, I | 1 |
| Osthaus, WA | 1 |
| Boethig, D | 1 |
| Winterhalter, M | 1 |
| Huber, D | 1 |
| Goerler, H | 1 |
| Sasse, M | 1 |
| Sümpelmann, R | 1 |
| Amirnovin, R | 1 |
| Keller, RL | 1 |
| Herrera, C | 1 |
| Hsu, JH | 1 |
| Datar, S | 1 |
| Karl, TR | 2 |
| Adatia, I | 1 |
| Oishi, P | 1 |
| Fineman, JR | 1 |
| CASTELLO, D | 1 |
| MADON, E | 1 |
| Miller, SP | 1 |
| McQuillen, PS | 1 |
| Vigneron, DB | 1 |
| Glidden, DV | 1 |
| Barkovich, AJ | 1 |
| Ferriero, DM | 1 |
| Hamrick, SE | 1 |
| Azakie, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Perioperative Levosimendan Administration in Neonates With Transposition of the Great Arteries: Randomized Controlled Trial[NCT01120106] | Phase 2 | 63 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for lactic acid and Transposition of Great Vessels
| Article | Year |
|---|---|
Magnetic Resonance Spectroscopy of Brain Metabolism in Fetuses With Congenital Heart Disease.
Topics: Brain; Choline; Female; Fetus; Heart Defects, Congenital; Humans; Infant; Lactic Acid; Magnetic Reso | 2023 |
Relationship Between Antiinflammatory Cytokine Interleukin-10 and Lactate Concentrations in Neonates Undergoing the Arterial Switch Operation.
Topics: Arterial Switch Operation; Biomarkers; Female; Humans; Infant, Newborn; Interleukin-10; Lactic Acid; | 2016 |
First experiences with intraoperative Levosimendan in pediatric cardiac surgery.
Topics: Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Heart; Heart D | 2009 |
B-type natriuretic peptide levels predict outcomes in infants undergoing cardiac surgery in a lesion-dependent fashion.
Topics: Biomarkers; Cardiac Surgical Procedures; Female; Heart Defects, Congenital; Heart Ventricles; Hemody | 2013 |
[BEHAVIOR OF BLOOD LACTIC ACID IN CHILDREN WITH HEART DISEASE. II. CONGENITAL HEART DISEASE].
Topics: Aortic Coarctation; Blood Chemical Analysis; Child; Ductus Arteriosus; Ductus Arteriosus, Patent; He | 1963 |
Preoperative brain injury in newborns with transposition of the great arteries.
Topics: Brain Injuries; Cardiopulmonary Bypass; Choline; Gestational Age; Humans; Infant, Newborn; Lactic Ac | 2004 |