lactic acid has been researched along with Syncope in 7 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Differentiating epileptic seizures from other causes of Transient Loss of Consciousness (TLOC) remains a challenge in the Emergency Department (ED), where it may lead to erroneous administration of anti-epileptic drugs." | 2.82 | Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis. ( Martinez, S; Patel, J; Pourmand, A; Tran, QK; Wright, H, 2022) |
| "A total of 383 cases of transient loss of consciousness were identified and categorized as tonic-clonic seizure (TCS), other seizure, syncope, or other cause, according to the final diagnosis in the electronic medical records system." | 1.62 | Prehospital lactate levels in blood as a seizure biomarker: A multi-center observational study. ( Axelsson, C; Edelvik Tranberg, A; Herlitz, J; Höglind, R; Magnusson, C; Wennberg, P; Zelano, J, 2021) |
| "Hypophosphatemia was recently reported as a potential marker of tonic-clonic (TC) seizures among patients with transitory loss of consciousness (TLOC)." | 1.56 | Hypophosphatemia compared to classical biomarkers of tonic clonic seizures. ( Barbella, G; Barras, P; Novy, J; Rossetti, AO, 2020) |
| "Regarding the first hour after the seizure, we identify a cut-off for serum lactate of 2." | 1.48 | Early postictal serum lactate concentrations are superior to serum creatine kinase concentrations in distinguishing generalized tonic-clonic seizures from syncopes. ( Brokmann, JC; Dafotakis, M; Heckelmann, J; Litmathe, J; Matz, O; Schulz, JB; Willmes, K; Zechbauer, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Brody, EI | 1 |
| Genuini, M | 1 |
| Auvin, S | 1 |
| Lodé, N | 1 |
| Brunet, SR | 1 |
| Patel, J | 1 |
| Tran, QK | 1 |
| Martinez, S | 1 |
| Wright, H | 1 |
| Pourmand, A | 1 |
| Barbella, G | 1 |
| Barras, P | 1 |
| Rossetti, AO | 1 |
| Novy, J | 1 |
| Magnusson, C | 1 |
| Herlitz, J | 1 |
| Höglind, R | 1 |
| Wennberg, P | 1 |
| Edelvik Tranberg, A | 1 |
| Axelsson, C | 1 |
| Zelano, J | 1 |
| Matz, O | 2 |
| Heckelmann, J | 1 |
| Zechbauer, S | 2 |
| Litmathe, J | 2 |
| Brokmann, JC | 1 |
| Willmes, K | 2 |
| Schulz, JB | 2 |
| Dafotakis, M | 2 |
| Pattarini, JM | 1 |
| Blue, RS | 1 |
| Aikins, LT | 1 |
| Law, J | 1 |
| Walshe, AD | 1 |
| Garbino, A | 1 |
| Turney, MW | 1 |
| Clark, JB | 1 |
| Zdebik, C | 1 |
| Bündgens, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Lactate Compared to Creatine Kinase as Diagnostic Marker in Generalized Epileptic Seizure[NCT02926703] | 85 participants (Actual) | Observational | 2015-11-30 | Completed | |||
| Serum Lactate in Convulsive Syncopes Compared to Non-convulsive Syncopes[NCT03062683] | 100 participants (Anticipated) | Observational | 2017-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Syncope
| Article | Year |
|---|---|
Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis.
Topics: Adult; Diagnosis, Differential; Electroencephalography; Epilepsy; Humans; Lactic Acid; Prospective S | 2022 |
Flat spin and negative Gz in high-altitude free fall: pathophysiology, prevention, and treatment.
Topics: Altitude; Arrhythmias, Cardiac; Blood Glucose; Brain Edema; Cerebrovascular Circulation; Confusion; | 2013 |
5 other studies available for lactic acid and Syncope
| Article | Year |
|---|---|
Prehospital capillary lactate in children differentiates epileptic seizure from febrile seizure, syncope, and psychogenic nonepileptic seizure.
Topics: Child; Diagnosis, Differential; Electroencephalography; Emergency Medical Services; Humans; Lactic A | 2022 |
Hypophosphatemia compared to classical biomarkers of tonic clonic seizures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Creatine Kinase; Diagnosis, Differential; Em | 2020 |
Prehospital lactate levels in blood as a seizure biomarker: A multi-center observational study.
Topics: Adult; Aged; Biomarkers; Diagnosis, Differential; Emergency Medical Services; Female; Humans; Lactic | 2021 |
Early postictal serum lactate concentrations are superior to serum creatine kinase concentrations in distinguishing generalized tonic-clonic seizures from syncopes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Creatine Kinase; Diagnosis, Differential; Em | 2018 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |