lactic acid has been researched along with Subarachnoid Hemorrhage in 74 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a clinical trial of inhaled hydrogen in patients with subarachnoid hemorrhage (SAH), we found that hydrogen reduced the accumulation of lactic acid in the nervous system." | 8.31 | Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway. ( Cao, BQ; Hang, CH; Li, W; Li, XJ; Lu, Y; Pang, C; Peng, Z; Sun, JQ; Wang, J; Zhang, JT; Zhang, YH; Zhu, Q; Zhuang, Z, 2023) |
| "Curcumin and nano-curcumin both exhibit neuroprotective effects in early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH)." | 7.85 | Enhanced Therapeutic Potential of Nano-Curcumin Against Subarachnoid Hemorrhage-Induced Blood-Brain Barrier Disruption Through Inhibition of Inflammatory Response and Oxidative Stress. ( Fan, CD; Fang, J; Fu, XT; Fu, XY; Hou, YJ; Jiang, M; Li, DW; Mao, LL; Sun, BL; Yang, MF; Yin, YX; Zhang, S; Zhang, ZY, 2017) |
| "To investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH)." | 7.78 | Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage. ( Bege, N; Beseoglu, K; Eicker, S; Etminan, N; Frauenknecht, K; Hänggi, D; Heiroth, HJ; Kamp, MA; Kissel, T; Macht, S; Perrin, J; Sommer, C; Steiger, HJ, 2012) |
| "Propofol infusion syndrome (PRIS) is a rare but frequently fatal condition." | 7.77 | Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. ( Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL, 2011) |
| "Endovascular treatment of intracranial aneurysms by using Matrix detachable coils is feasible and demonstrated initial angiographic results and overall morbidity and mortality rates that are within the ranges found in the literature in the use of bare platinum coils." | 5.12 | Endovascular treatment of intracranial aneurysms with matrix detachable coils: immediate posttreatment results from a prospective multicenter registry. ( Bonafé, A; Bracard, S; Leclerc, X; Pierot, L, 2006) |
| " The authors' goal was to characterize patterns of markers of energy metabolism (glucose, pyruvate, and lactate) and neuronal injury (glutamate and glycerol) in patients with subarachnoid hemorrhage (SAH), in whom ischemia was or was not suspected." | 5.09 | Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage. ( Bjerre, P; Schulz, MK; Tange, M; Wang, LP, 2000) |
| " In a clinical trial of inhaled hydrogen in patients with subarachnoid hemorrhage (SAH), we found that hydrogen reduced the accumulation of lactic acid in the nervous system." | 4.31 | Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway. ( Cao, BQ; Hang, CH; Li, W; Li, XJ; Lu, Y; Pang, C; Peng, Z; Sun, JQ; Wang, J; Zhang, JT; Zhang, YH; Zhu, Q; Zhuang, Z, 2023) |
| "Curcumin and nano-curcumin both exhibit neuroprotective effects in early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH)." | 3.85 | Enhanced Therapeutic Potential of Nano-Curcumin Against Subarachnoid Hemorrhage-Induced Blood-Brain Barrier Disruption Through Inhibition of Inflammatory Response and Oxidative Stress. ( Fan, CD; Fang, J; Fu, XT; Fu, XY; Hou, YJ; Jiang, M; Li, DW; Mao, LL; Sun, BL; Yang, MF; Yin, YX; Zhang, S; Zhang, ZY, 2017) |
| " The aim of this study was to clarify the association between lactic acidosis and NPE in patients with nontraumatic SAH." | 3.80 | Association between serum lactate levels and early neurogenic pulmonary edema after nontraumatic subarachnoid hemorrhage. ( Fuse, A; Gemma, A; Matsumoto, G; Onda, H; Satoh, E; Suzuki, G; Tagami, T; Watanabe, A; Yokota, H, 2014) |
| "To investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH)." | 3.78 | Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage. ( Bege, N; Beseoglu, K; Eicker, S; Etminan, N; Frauenknecht, K; Hänggi, D; Heiroth, HJ; Kamp, MA; Kissel, T; Macht, S; Perrin, J; Sommer, C; Steiger, HJ, 2012) |
| "Propofol infusion syndrome (PRIS) is a rare but frequently fatal condition." | 3.77 | Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. ( Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL, 2011) |
| "Bedside intracerebral microdialysis monitoring of patients with subarachnoid hemorrhage and signs of delayed ischemia revealed dramatic changes in extracellular concentrations of glucose, lactate, and glycerol that could be directly correlated to the clinical status of the patients." | 3.70 | Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration. ( Brandt, L; Nilsson, OG; Säveland, H; Ungerstedt, U, 1999) |
| "The majority of patients with poor-grade subarachnoid hemorrhage (SAH), that is, World Federation of Neurosurgical Societies (WFNS) Grades IV and V, have high morbidity and mortality rates." | 2.71 | Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome. ( Haux, D; Küchler, I; Lanksch, WR; Sarrafzadeh, A; Unterberg, AW, 2004) |
| "Thirteen subarachnoid hemorrhage patients (age, 48." | 2.71 | Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study. ( Amthauer, H; Haux, D; Küchler, I; Lüdemann, L; Plotkin, M; Sarrafzadeh, AS; Unterberg, AW, 2004) |
| "Delayed cerebral ischemia (DCI) is a devastating complication of aneurysmal subarachnoid hemorrhage (ASAH) causing brain infarction and disability." | 1.91 | Early brain metabolic disturbances associated with delayed cerebral ischemia in patients with severe subarachnoid hemorrhage. ( Aboudhiaf, S; Balança, B; Barcelos, GK; Carrillon, R; Dailler, F; Grousson, S; Lieutaud, T; Marinesco, S; Perret-Liaudet, A; Tholance, Y, 2023) |
| "Delayed cerebral ischemia (DCI), which encompasses all neurobiological events occurring in the subacute-late stage after aSAH, has a complex pathogenesis and can occur in the absence of instrumental vasospasm." | 1.91 | Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage. ( Balducci, MT; Blagia, M; Bozzi, MT; Chibbaro, S; de Gennaro, L; De Robertis, M; Messina, R; Pop, R; Severac, F; Signorelli, F, 2023) |
| "The pathophysiology of delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH) has not been fully evaluated." | 1.56 | Lactate and Lactate Dehydrogenase in Cistern as Biomarkers of Early Brain Injury and Delayed Cerebral Ischemia of Subarachnoid Hemorrhage. ( Anan, M; Fudaba, H; Fujiki, M; Nagai, Y, 2020) |
| "In patients with subarachnoid hemorrhage (SAH), abnormalities in glucose and lactate metabolism have been described using cerebral microdialysis." | 1.56 | Cerebrospinal Fluid Glucose and Lactate Levels After Subarachnoid Hemorrhage: A Multicenter Retrospective Study. ( Arib, S; Badenes, R; Bilotta, F; Bouhemad, B; Creteur, J; Crippa, IA; Franchi, F; Gordon, S; Lozano Roig, A; Mirek, S; Nadji, A; Rubulotta, F; Stazi, E; Taccone, FS, 2020) |
| "OBJECTIVE Delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH) is one of the major contributors to poor outcome." | 1.48 | Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage. ( Enblad, P; Engquist, H; Hillered, L; Howells, T; Johnson, U; Lewén, A; Nilsson, P; Ronne-Engström, E; Rostami, E, 2018) |
| "Aneurysmal subarachnoid hemorrhage (SAH) is the most devastating form of hemorrhagic stroke." | 1.43 | Admission serum lactate predicts mortality in aneurysmal subarachnoid hemorrhage. ( Aisiku, IP; Chen, PR; Edlow, J; Monsivais, DR; Truong, H, 2016) |
| "Early lactate and glucose levels after aneurysmal subarachnoid hemorrhage are associated with delayed cerebral ischemia and poor outcome, suggesting that they may be considered in conjunction with other parameters for future prognostic models." | 1.43 | Early Circulating Lactate and Glucose Levels After Aneurysmal Subarachnoid Hemorrhage Correlate With Poor Outcome and Delayed Cerebral Ischemia: A Two-Center Cohort Study. ( Bakker, J; Dijkland, SA; Dippel, DW; Nijsten, MW; van den Bergh, WM; van der Jagt, M; van Donkelaar, CE, 2016) |
| "In severe aneurysmal subarachnoid hemorrhage (aSAH), pathological changes in cerebral energy metabolism can be detected either by local measurements using cerebral microdialysis (cMD) together with brain tissue oxygen probe or by global measurements of arterio-jugular difference performed with retrograde jugular vein catheter." | 1.42 | Biochemical neuromonitoring of poor-grade aneurysmal subarachnoid hemorrhage: comparative analysis of metabolic events detected by cerebral microdialysis and by retrograde jugular vein catheterization. ( Barcelos, GK; Dailler, F; Marinesco, S; Perret-Liaudet, A; Renaud, B; Tholance, Y, 2015) |
| "Aneurysmal subarachnoid hemorrhage (SAH) is frequently associated with delayed neurological deterioration (DND)." | 1.40 | Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage. ( Jacobsen, A; Nielsen, TH; Nilsson, O; Nordström, CH; Schalén, W, 2014) |
| "In patients with poor-grade subarachnoid hemorrhage, global cerebral edema is associated with early brain metabolic distress." | 1.37 | Global cerebral edema and brain metabolism after subarachnoid hemorrhage. ( Badjatia, N; Choi, HA; Claassen, J; Connolly, ES; Fernandez, L; Helbok, R; Ko, SB; Kurtz, P; Lee, K; Mayer, SA; Schmidt, JM, 2011) |
| "Previous studies of spontaneous subarachnoid hemorrhage (SAH) have shown that global cerebral edema on the first computed tomography scan is associated with a more severe initial injury and is an independent predictor of poor outcome." | 1.36 | Brain energy metabolism in patients with spontaneous subarachnoid hemorrhage and global cerebral edema. ( Enblad, P; Hallberg, L; Hillered, L; Karlsson, T; Ronne Engström, E; Zetterling, M, 2010) |
| "We studied 14 comatose SAH patients who underwent multimodality neuromonitoring with intracranial pressure (ICP) and cerebral microdialysis as part of their clinical care." | 1.36 | Brain interstitial fluid TNF-alpha after subarachnoid hemorrhage. ( Badjatia, N; Connolly, ES; Fernandez, L; Grobelny, B; Hanafy, KA; Kurtz, P; Mayer, SA; Schindler, C, 2010) |
| "Rabbits whose cerebral vasospasm were 50% or over 50% (n=7) and NSS is lesser than 3 were termed as groups 2, and rabbits whose cerebral vasospasm were 50% or above 50% (n=7) and NSS is greater than 3 were termed groups 3." | 1.34 | Lactate contents from cerebrospinal fluid in experimental subarachnoid hemorrhage, well correlate with vasospasm: ongoing and neurologic status. ( Ak, A; Cengiz, SL; Karaköse, S; Ustün, ME, 2007) |
| "After subarachnoid hemorrhage (SAH) cerebral metabolism is significantly impaired." | 1.34 | Cerebral energy failure after subarachnoid hemorrhage: the role of relative hyperglycolysis. ( Böker, DK; Oertel, MF; Scharbrodt, W; Schmidinger, A; Schwedler, M; Stein, M; Wachter, D, 2007) |
| "Hyperglycemia after aneurysmal subarachnoid hemorrhage (SAH) is associated with serious complications." | 1.34 | Impact of hyperglycemia on neurological deficits and extracellular glucose levels in aneurysmal subarachnoid hemorrhage patients. ( Haux, D; Kerner, A; Sakowitz, O; Sarrafzadeh, A; Schlenk, F, 2007) |
| "Age, sex distribution, unruptured aneurysm cases, and multiple aneurysm cases were similar in the 2 groups." | 1.33 | Guglielmi detachable coils versus matrix coils: a comparison of the immediate posttreatment results of the embolization of 364 cerebral aneurysms in 307 patients: a single-center, single-surgeon experience. ( Katsaridis, V; Papagiannaki, C; Violaris, C, 2006) |
| "In a 36-year-old man, an anterior communicating artery aneurysm caused an SAH (Hunt and Hess Grade IV, Fisher Grade III)." | 1.32 | Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report. ( Behr, R; Hoelper, BM; Hofmann, E; Soldner, F; Sporleder, R, 2003) |
| "In the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH), early occlusion of the aneurysm is necessary as well as monitoring and treatment of complications following the primary bleeding episode." | 1.32 | Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage. ( Bjerre, P; Kristensen, SR; Schulz, M; Skjøth-Rasmussen, J, 2004) |
| "Even though cerebral vasospasm after subarachnoid hemorrhage (SAH) causes cerebral ischemia or infarction, the metabolic alterations in cerebrospinal fluids (CSF) after SAH have not been studied." | 1.31 | Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs. ( Aoki, K; Badr, A; Tibbs, R; Yin, W; Zhang, J, 2001) |
| "Forty patients (35 after subarachnoid hemorrhage and 5 after complex aneurysm surgery) were monitored for a total of 174 days (mean, 4 d; range, 1-12 d)." | 1.31 | Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes. ( Al-Rawi, PG; Gupta, AK; Hutchinson, PJ; Kett-White, R; Kirkpatrick, PJ; Pickard, JD, 2002) |
| "Lactic acid levels were significantly elevated from sham animals in each region within the first hour (p<0." | 1.30 | Lactate and free fatty acids after subarachnoid hemorrhage. ( DeAtley, SM; Dhillon, HS; Gewirtz, RJ; Goes, SE; Scheff, SW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.35) | 18.7374 |
| 1990's | 7 (9.46) | 18.2507 |
| 2000's | 29 (39.19) | 29.6817 |
| 2010's | 25 (33.78) | 24.3611 |
| 2020's | 12 (16.22) | 2.80 |
| Authors | Studies |
|---|---|
| Svedung Wettervik, T | 1 |
| Hånell, A | 1 |
| Howells, T | 3 |
| Ronne-Engström, E | 6 |
| Enblad, P | 7 |
| Lewén, A | 3 |
| Messina, R | 3 |
| de Gennaro, L | 3 |
| De Robertis, M | 3 |
| Pop, R | 3 |
| Chibbaro, S | 3 |
| Severac, F | 3 |
| Blagia, M | 3 |
| Balducci, MT | 3 |
| Bozzi, MT | 3 |
| Signorelli, F | 3 |
| Fang, H | 1 |
| Wang, S | 1 |
| Lang, L | 1 |
| Yang, C | 1 |
| Ho, WM | 1 |
| Schmidt, FA | 1 |
| Thomé, C | 5 |
| Petr, O | 1 |
| Peng, Z | 1 |
| Li, XJ | 1 |
| Pang, C | 1 |
| Zhang, JT | 1 |
| Zhu, Q | 1 |
| Sun, JQ | 1 |
| Wang, J | 1 |
| Cao, BQ | 1 |
| Zhang, YH | 1 |
| Lu, Y | 1 |
| Li, W | 1 |
| Hang, CH | 1 |
| Zhuang, Z | 1 |
| Tholance, Y | 2 |
| Aboudhiaf, S | 1 |
| Balança, B | 1 |
| Barcelos, GK | 2 |
| Grousson, S | 1 |
| Carrillon, R | 1 |
| Lieutaud, T | 1 |
| Perret-Liaudet, A | 2 |
| Dailler, F | 2 |
| Marinesco, S | 2 |
| Forsse, A | 1 |
| Nielsen, TH | 2 |
| Mølstrøm, S | 1 |
| Hjelmborg, J | 1 |
| Nielsen, KS | 1 |
| Nygaard, KH | 1 |
| Yilmaz, S | 1 |
| Nordström, CH | 2 |
| Poulsen, FR | 1 |
| Anan, M | 1 |
| Nagai, Y | 1 |
| Fudaba, H | 1 |
| Fujiki, M | 1 |
| Hosmann, A | 2 |
| Schnackenburg, P | 1 |
| Rauscher, S | 1 |
| Hopf, A | 1 |
| Bohl, I | 1 |
| Engel, A | 1 |
| Brugger, J | 1 |
| Graf, A | 1 |
| Plöchl, W | 1 |
| Reinprecht, A | 2 |
| Gruber, A | 1 |
| Milivojev, N | 1 |
| Dumitrescu, S | 1 |
| Weidinger, A | 1 |
| Kozlov, AV | 1 |
| Rostami, E | 1 |
| Engquist, H | 1 |
| Johnson, U | 1 |
| Nilsson, P | 3 |
| Hillered, L | 7 |
| Cesak, T | 1 |
| Adamkov, J | 1 |
| Habalova, J | 1 |
| Poczos, P | 1 |
| Kanta, M | 1 |
| Bartos, M | 1 |
| Hosszu, T | 1 |
| Zhou, T | 1 |
| Kalanuria, A | 1 |
| Lindgren, C | 1 |
| Koskinen, LO | 1 |
| Ssozi, R | 1 |
| Naredi, S | 1 |
| Kofler, M | 2 |
| Gaasch, M | 2 |
| Rass, V | 2 |
| Schiefecker, AJ | 2 |
| Ianosi, B | 2 |
| Lindner, A | 1 |
| Beer, R | 3 |
| Stover, JF | 2 |
| Rhomberg, P | 1 |
| Pfausler, B | 3 |
| Schmutzhard, E | 2 |
| Helbok, R | 6 |
| Taccone, FS | 1 |
| Badenes, R | 1 |
| Arib, S | 1 |
| Rubulotta, F | 1 |
| Mirek, S | 1 |
| Franchi, F | 1 |
| Gordon, S | 1 |
| Nadji, A | 1 |
| Crippa, IA | 1 |
| Stazi, E | 1 |
| Bouhemad, B | 1 |
| Lozano Roig, A | 1 |
| Creteur, J | 1 |
| Bilotta, F | 1 |
| Solari, D | 1 |
| Miroz, JP | 1 |
| Morelli, P | 1 |
| Oddo, M | 2 |
| Schiefecker, A | 1 |
| Delazer, M | 1 |
| Bodner, T | 1 |
| Benke, T | 1 |
| Lackner, P | 1 |
| Fischer, M | 1 |
| Sohm, F | 1 |
| Hackl, W | 1 |
| Humpel, C | 1 |
| Jacobsen, A | 1 |
| Nilsson, O | 1 |
| Schalén, W | 1 |
| Satoh, E | 1 |
| Tagami, T | 1 |
| Watanabe, A | 1 |
| Matsumoto, G | 1 |
| Suzuki, G | 1 |
| Onda, H | 1 |
| Fuse, A | 1 |
| Gemma, A | 1 |
| Yokota, H | 1 |
| Renaud, B | 1 |
| Chang, CZ | 1 |
| Wu, SC | 1 |
| Lin, CL | 1 |
| Kwan, AL | 1 |
| Wang, KC | 1 |
| Tang, SC | 1 |
| Lee, JE | 1 |
| Jeng, JS | 1 |
| Lai, DM | 1 |
| Huang, SJ | 1 |
| Hsieh, ST | 1 |
| Tu, YK | 1 |
| Zhang, ZY | 1 |
| Jiang, M | 1 |
| Fang, J | 1 |
| Yang, MF | 1 |
| Zhang, S | 1 |
| Yin, YX | 1 |
| Li, DW | 1 |
| Mao, LL | 1 |
| Fu, XY | 1 |
| Hou, YJ | 1 |
| Fu, XT | 1 |
| Fan, CD | 1 |
| Sun, BL | 1 |
| van Donkelaar, CE | 1 |
| Dijkland, SA | 1 |
| van den Bergh, WM | 1 |
| Bakker, J | 1 |
| Dippel, DW | 1 |
| Nijsten, MW | 1 |
| van der Jagt, M | 1 |
| Aisiku, IP | 1 |
| Chen, PR | 1 |
| Truong, H | 1 |
| Monsivais, DR | 1 |
| Edlow, J | 1 |
| Patet, C | 1 |
| Quintard, H | 1 |
| Zerlauth, JB | 1 |
| Maibach, T | 1 |
| Carteron, L | 1 |
| Suys, T | 1 |
| Bouzat, P | 1 |
| Bervini, D | 1 |
| Levivier, M | 1 |
| Daniel, RT | 1 |
| Eckert, P | 1 |
| Meuli, R | 1 |
| Schubert, GA | 1 |
| Poli, S | 1 |
| Schilling, L | 1 |
| Heiland, S | 1 |
| Nagel, A | 1 |
| Graetz, D | 1 |
| Schink, T | 1 |
| Frieler, K | 1 |
| Sakowitz, O | 2 |
| Vajkoczy, P | 2 |
| Sarrafzadeh, A | 4 |
| Samuelsson, C | 2 |
| Kumlien, E | 2 |
| Hanafy, KA | 2 |
| Grobelny, B | 1 |
| Fernandez, L | 4 |
| Kurtz, P | 4 |
| Connolly, ES | 4 |
| Mayer, SA | 4 |
| Schindler, C | 1 |
| Badjatia, N | 4 |
| Schmidt, JM | 2 |
| Stuart, RM | 1 |
| Presciutti, M | 1 |
| Ostapkovich, ND | 1 |
| Lee, K | 3 |
| Claassen, J | 3 |
| Zetterling, M | 3 |
| Hallberg, L | 1 |
| Karlsson, T | 2 |
| Ronne Engström, E | 1 |
| Schlenk, F | 2 |
| Gericke, C | 1 |
| Pisapia, JM | 1 |
| Wendell, LC | 1 |
| Kumar, MA | 1 |
| Zager, EL | 1 |
| Levine, JM | 1 |
| Madineni, RC | 1 |
| Schmidt, MJ | 1 |
| Ko, SB | 2 |
| Choi, A | 1 |
| Stuart, MR | 1 |
| Khandji, AG | 1 |
| Choi, HA | 1 |
| Stein, M | 2 |
| Schomacher, J | 1 |
| Scharbrodt, W | 2 |
| Preuss, M | 1 |
| Oertel, MF | 2 |
| Hänggi, D | 1 |
| Perrin, J | 1 |
| Eicker, S | 1 |
| Beseoglu, K | 1 |
| Etminan, N | 1 |
| Kamp, MA | 1 |
| Heiroth, HJ | 1 |
| Bege, N | 1 |
| Macht, S | 1 |
| Frauenknecht, K | 1 |
| Sommer, C | 1 |
| Kissel, T | 1 |
| Steiger, HJ | 1 |
| Macmillan, CS | 1 |
| Wild, JM | 1 |
| Wardlaw, JM | 1 |
| Andrews, PJ | 1 |
| Marshall, I | 1 |
| Easton, VJ | 1 |
| Cesarini, KG | 1 |
| Marklund, N | 2 |
| Salci, K | 2 |
| Hårdemark, HG | 1 |
| Persson, L | 2 |
| Hoelper, BM | 1 |
| Hofmann, E | 1 |
| Sporleder, R | 1 |
| Soldner, F | 1 |
| Behr, R | 1 |
| Skjøth-Rasmussen, J | 1 |
| Schulz, M | 1 |
| Kristensen, SR | 1 |
| Bjerre, P | 2 |
| Sarrafzadeh, AS | 2 |
| Haux, D | 3 |
| Lüdemann, L | 1 |
| Amthauer, H | 1 |
| Plotkin, M | 1 |
| Küchler, I | 2 |
| Unterberg, AW | 3 |
| Lanksch, WR | 2 |
| Hillman, J | 1 |
| Milos, P | 1 |
| Yu, ZQ | 1 |
| Sjögren, F | 1 |
| Anderson, C | 1 |
| Mellergård, P | 1 |
| Bhatia, R | 1 |
| Hashemi, P | 1 |
| Razzaq, A | 1 |
| Parkin, MC | 1 |
| Hopwood, SE | 1 |
| Boutelle, MG | 1 |
| Strong, AJ | 1 |
| Chiang, MF | 1 |
| Chiu, WT | 1 |
| Lin, FJ | 1 |
| Thajeb, P | 1 |
| Huang, CJ | 1 |
| Tsai, SH | 1 |
| Pierot, L | 1 |
| Bonafé, A | 1 |
| Bracard, S | 1 |
| Leclerc, X | 1 |
| Katsaridis, V | 1 |
| Papagiannaki, C | 1 |
| Violaris, C | 1 |
| Heros, RC | 1 |
| Zauner, A | 1 |
| Murayama, Y | 1 |
| Viñuela, F | 1 |
| Ishii, A | 1 |
| Nien, YL | 1 |
| Yuki, I | 1 |
| Duckwiler, G | 1 |
| Jahan, R | 1 |
| Hesselager, G | 1 |
| Ryttlefors, M | 1 |
| Cengiz, SL | 1 |
| Ak, A | 1 |
| Ustün, ME | 1 |
| Karaköse, S | 1 |
| Schwedler, M | 1 |
| Wachter, D | 1 |
| Schmidinger, A | 1 |
| Böker, DK | 1 |
| Eide, PK | 1 |
| Bentsen, G | 1 |
| Stanisic, M | 1 |
| Stubhaug, A | 1 |
| Kerner, A | 1 |
| Wong, GK | 1 |
| Poon, WS | 1 |
| Ip, M | 1 |
| Landolt, H | 1 |
| Langemann, H | 1 |
| Mendelowitsch, A | 1 |
| Gratzl, O | 1 |
| Mori, K | 1 |
| Nakajima, K | 1 |
| Maeda, M | 1 |
| Sahuquillo, J | 1 |
| Poca, MA | 1 |
| Garnacho, A | 1 |
| Robles, A | 1 |
| Coello, F | 1 |
| Godet, C | 1 |
| Triginer, C | 1 |
| Rubio, E | 1 |
| Rowe, J | 1 |
| Blamire, AM | 1 |
| Domingo, Z | 1 |
| Moody, V | 1 |
| Molyneux, A | 1 |
| Byrne, J | 1 |
| Cadoux-Hudson, T | 1 |
| Radda, G | 1 |
| Gewirtz, RJ | 1 |
| Dhillon, HS | 1 |
| Goes, SE | 1 |
| DeAtley, SM | 1 |
| Scheff, SW | 1 |
| Nilsson, OG | 1 |
| Brandt, L | 1 |
| Ungerstedt, U | 1 |
| Säveland, H | 1 |
| Hutchinson, PJ | 2 |
| O'Connell, MT | 1 |
| Al-Rawi, PG | 2 |
| Maskell, LB | 1 |
| Kett-White, R | 2 |
| Gupta, AK | 2 |
| Richards, HK | 1 |
| Hutchinson, DB | 1 |
| Kirkpatrick, PJ | 2 |
| Pickard, JD | 2 |
| Schulz, MK | 1 |
| Wang, LP | 1 |
| Tange, M | 1 |
| Staub, F | 1 |
| Graf, R | 1 |
| Gabel, P | 1 |
| Köchling, M | 1 |
| Klug, N | 1 |
| Heiss, WD | 1 |
| Yin, W | 1 |
| Tibbs, R | 1 |
| Aoki, K | 1 |
| Badr, A | 1 |
| Zhang, J | 1 |
| Sakowitz, OW | 1 |
| Benndorf, G | 1 |
| De Micheli, E | 1 |
| Pinna, G | 1 |
| Alfieri, A | 1 |
| Caramia, G | 1 |
| Bianchi, L | 1 |
| Colivicchi, MA | 1 |
| Della Corte, L | 1 |
| Bricolo, A | 1 |
| Shimoda, M | 1 |
| Yamada, S | 1 |
| Yamamoto, I | 1 |
| Tsugane, R | 1 |
| Sato, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779] | 12 participants (Actual) | Observational | 2017-08-28 | Completed | |||
| Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage[NCT03987139] | 45 participants (Anticipated) | Interventional | 2019-06-15 | Active, not recruiting | |||
| APPLY Study: A Prospective, Single Center Study Appraising the Embolization of Aneurysms Using the Balt Optima™ Coil System[NCT04499508] | 30 participants (Anticipated) | Interventional | 2020-04-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
CSF metabolomics alterations after aneurysmal subarachnoid hemorrhage: what do we know?
Topics: Biomarkers; Brain Ischemia; Humans; Lactic Acid; Pyruvic Acid; Subarachnoid Hemorrhage | 2023 |
Cerebral Microdialysis in Neurocritical Care.
Topics: Biomarkers; Brain Injuries; Brain Injuries, Traumatic; Glucose; Humans; Lactic Acid; Microdialysis; | 2018 |
7 trials available for lactic acid and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.
Topics: Adult; Aged; Biomarkers; Blood Flow Velocity; Brain; Brain Ischemia; Cerebrovascular Circulation; Ex | 2004 |
Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome.
Topics: Brain; Disability Evaluation; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; Hyperglyce | 2004 |
Application of rapid-sampling, online microdialysis to the monitoring of brain metabolism during aneurysm surgery.
Topics: Adult; Aged; Aneurysm; Brain; Craniotomy; Female; Glucose; Humans; Lactic Acid; Male; Microdialysis; | 2006 |
Endovascular treatment of intracranial aneurysms with matrix detachable coils: immediate posttreatment results from a prospective multicenter registry.
Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Brain Damage, Chronic; Cerebral Angiography; Coated Mat | 2006 |
Initial clinical experience with matrix detachable coils for the treatment of intracranial aneurysms.
Topics: Absorbable Implants; Adult; Aneurysm, Ruptured; Cerebral Angiography; Coated Materials, Biocompatibl | 2006 |
Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain; Brain Death; Brain Ischemia; Cerebral Angiography; Extracellular Space; Glucose; | 2000 |
Role of bedside microdialysis in the diagnosis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain; Cerebral Angiography; Cerebrovascular Circulation; Critical Care; Female; Glucos | 2001 |
65 other studies available for lactic acid and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Association of Arterial Metabolic Content with Cerebral Blood Flow Regulation and Cerebral Energy Metabolism-A Multimodality Analysis in Aneurysmal Subarachnoid Hemorrhage.
Topics: Carbon Dioxide; Cerebrovascular Circulation; Energy Metabolism; Glucose; Humans; Lactic Acid; Oxygen | 2022 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Cerebrospinal Fluid Lactate and Glucose Levels as Predictors of Symptomatic Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Brain Ischemia; Cerebral Infarction; Humans; Lactic Ac | 2023 |
Association of Cerebrospinal Fluid Biomarkers with Submental and Cerebral Hemorrhage: A Case-Control Study.
Topics: Biomarkers; Case-Control Studies; Cerebral Hemorrhage; Humans; Lactic Acid; Retrospective Studies; S | 2023 |
Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway.
Topics: Animals; Blotting, Western; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Respiratory Ther | 2023 |
Early brain metabolic disturbances associated with delayed cerebral ischemia in patients with severe subarachnoid hemorrhage.
Topics: Brain; Brain Ischemia; Cerebral Infarction; Glucose; Glutamic Acid; Humans; Lactic Acid; Pyruvic Aci | 2023 |
A Prospective Observational Feasibility Study of Jugular Bulb Microdialysis in Subarachnoid Hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Cerebrovascular Circulation; Feasibility Studies | 2020 |
Lactate and Lactate Dehydrogenase in Cistern as Biomarkers of Early Brain Injury and Delayed Cerebral Ischemia of Subarachnoid Hemorrhage.
Topics: Aged; Biomarkers; Brain Ischemia; Female; Humans; Hydrocephalus; L-Lactate Dehydrogenase; Lactic Aci | 2020 |
Brain Tissue Oxygen Response as Indicator for Cerebral Lactate Levels in Aneurysmal Subarachnoid Hemorrhage Patients.
Topics: Brain; Humans; Lactic Acid; Microdialysis; Oxygen; Prospective Studies; Subarachnoid Hemorrhage | 2022 |
Cerebral nitric oxide and mitochondrial function in patients suffering aneurysmal subarachnoid hemorrhage-a translational approach.
Topics: Animals; Brain Ischemia; Cerebrum; Energy Metabolism; Female; Glutamic Acid; Humans; Lactic Acid; Ma | 2021 |
Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Cerebr | 2018 |
The relationship between intracranial pressure and lactate/pyruvate ratio in patients with subarachnoid haemorrhage.
Topics: Aneurysm, Ruptured; Brain; Humans; Intracranial Aneurysm; Intracranial Hypertension; Intracranial Pr | 2018 |
Cerebrospinal fluid lactate and neurological outcome after subarachnoid haemorrhage.
Topics: Adult; Aged; Biomarkers; Endovascular Procedures; Female; Glasgow Outcome Scale; Humans; Lactic Acid | 2019 |
The Importance of Probe Location for the Interpretation of Cerebral Microdialysis Data in Subarachnoid Hemorrhage Patients.
Topics: Aged; Aneurysm, Ruptured; Brain; Brain Edema; Brain Ischemia; Cohort Studies; Female; Glucose; Gluta | 2020 |
Cerebrospinal Fluid Glucose and Lactate Levels After Subarachnoid Hemorrhage: A Multicenter Retrospective Study.
Topics: Aged; Blood Glucose; Brain; Cohort Studies; Female; Glucose; Humans; Lactic Acid; Male; Middle Aged; | 2020 |
Protocolized Brain Oxygen Optimization in Subarachnoid Hemorrhage.
Topics: Aged; Brain; Carbon Dioxide; Cerebrovascular Circulation; Clinical Protocols; Cohort Studies; Female | 2019 |
Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome.
Topics: Aged; Biomarkers; Brain; Cognition Disorders; Female; Follow-Up Studies; Glutamic Acid; Humans; Intr | 2015 |
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage.
Topics: Aged; Biomarkers; Brain Ischemia; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Human | 2014 |
Association between serum lactate levels and early neurogenic pulmonary edema after nontraumatic subarachnoid hemorrhage.
Topics: Acidosis; Age Factors; Aged; Female; Glucose; Humans; Lactic Acid; Male; Middle Aged; Pulmonary Edem | 2014 |
Biochemical neuromonitoring of poor-grade aneurysmal subarachnoid hemorrhage: comparative analysis of metabolic events detected by cerebral microdialysis and by retrograde jugular vein catheterization.
Topics: Adolescent; Adult; Biomarkers; Brain; Catheterization; Female; Glasgow Outcome Scale; Humans; Intrac | 2015 |
Curcumin, encapsulated in nano-sized PLGA, down-regulates nuclear factor κB (p65) and subarachnoid hemorrhage induced early brain injury in a rat model.
Topics: Analysis of Variance; Animals; Biocompatible Materials; Brain Injuries; Caspase 3; Caspase 9; Curcum | 2015 |
Intrathecal lactate predicting hydrocephalus after aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Cerebral Ventricles; Cerebrospinal Fluid; Cerebrospinal Fluid Shunts | 2015 |
Enhanced Therapeutic Potential of Nano-Curcumin Against Subarachnoid Hemorrhage-Induced Blood-Brain Barrier Disruption Through Inhibition of Inflammatory Response and Oxidative Stress.
Topics: Animals; Blood-Brain Barrier; Curcumin; Dose-Response Relationship, Drug; Inflammation Mediators; La | 2017 |
Early Circulating Lactate and Glucose Levels After Aneurysmal Subarachnoid Hemorrhage Correlate With Poor Outcome and Delayed Cerebral Ischemia: A Two-Center Cohort Study.
Topics: Aged; Biomarkers; Blood Glucose; Brain Ischemia; Female; Humans; Intensive Care Units; Lactic Acid; | 2016 |
Admission serum lactate predicts mortality in aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Female; Hospitalization; Humans; Lactic Acid; Male; Middle Aged; Prognosis; Retrospecti | 2016 |
Bedside cerebral microdialysis monitoring of delayed cerebral hypoperfusion in comatose patients with poor grade aneurysmal subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Blood Glucose; Brain; Brain Ischemia; Cohort Studies; Coma; Critica | 2017 |
Hypothermia reduces cytotoxic edema and metabolic alterations during the acute phase of massive SAH: a diffusion-weighted imaging and spectroscopy study in rats.
Topics: Acute Disease; Animals; Aspartic Acid; Body Temperature; Brain; Brain Edema; Cerebral Cortex; Creati | 2008 |
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutam | 2009 |
Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage. Clinical article.
Topics: Aged; Biomarkers; Blood Pressure; Cerebrovascular Circulation; Critical Care; Energy Metabolism; Fem | 2009 |
Brain interstitial fluid TNF-alpha after subarachnoid hemorrhage.
Topics: Adult; Blood Glucose; Brain; Cohort Studies; Coma; Extracellular Fluid; Female; Glucose; Humans; Int | 2010 |
Systemic glucose and brain energy metabolism after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Brain; Critical Care; Energy Metaboli | 2010 |
Brain energy metabolism in patients with spontaneous subarachnoid hemorrhage and global cerebral edema.
Topics: Biomarkers; Brain; Brain Chemistry; Brain Edema; Energy Metabolism; Extracellular Fluid; Glucose; Hu | 2010 |
Relevance of cerebral interleukin-6 after aneurysmal subarachnoid hemorrhage.
Topics: Biomarkers; Brain Ischemia; C-Reactive Protein; Critical Care; Encephalitis; Extracellular Fluid; Fe | 2010 |
Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage.
Topics: Adult; Biomarkers; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lactic Acid; Pro | 2011 |
Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage.
Topics: Adult; Asymptomatic Diseases; Brain; Cerebral Infarction; Critical Care; Female; Glucose; Humans; La | 2011 |
Relation between brain interstitial and systemic glucose concentrations after subarachnoid hemorrhage.
Topics: Aged; Blood Glucose; Brain; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hyp | 2011 |
Global cerebral edema and brain metabolism after subarachnoid hemorrhage.
Topics: Brain; Brain Edema; Female; Glucose; Humans; Lactic Acid; Middle Aged; Oxygen; Prospective Studies; | 2011 |
Cerebrospinal fluid lactate concentration after withdrawal of metabolic suppressive therapy in subarachnoid hemorrhage.
Topics: Adult; Aged; Female; Fentanyl; Glasgow Outcome Scale; Humans; Hypnotics and Sedatives; Intensive Car | 2012 |
Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage.
Topics: Angiography, Digital Subtraction; Animals; Brain; Calcium-Binding Proteins; Delayed-Action Preparati | 2012 |
Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Child; Choline; Creatine; C | 2002 |
Early cerebral hyperglycolysis after subarachnoid haemorrhage correlates with favourable outcome.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain; Embolization, Therapeutic; Energy Metabolism; Female; | 2002 |
Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report.
Topics: Adult; Angioplasty, Balloon; Blood Flow Velocity; Blood Glucose; Brain; Carotid Artery, Internal; Ca | 2003 |
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma | 2004 |
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma | 2004 |
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma | 2004 |
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma | 2004 |
Intracerebral microdialysis in neurosurgical intensive care patients utilising catheters with different molecular cut-off (20 and 100 kD).
Topics: Brain Chemistry; Brain Injuries; Catheters, Indwelling; Cerebral Cortex; Coma; Critical Care; Extrac | 2006 |
Multiparametric analysis of cerebral substrates and nitric oxide delivery in cerebrospinal fluid in patients with intracerebral haemorrhage: correlation with hemodynamics and outcome.
Topics: Adult; Aged; Amino Acids; Carbohydrates; Cerebral Hemorrhage; Cerebrospinal Fluid; Cerebrovascular C | 2006 |
Guglielmi detachable coils versus matrix coils: a comparison of the immediate posttreatment results of the embolization of 364 cerebral aneurysms in 307 patients: a single-center, single-surgeon experience.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Coated Materials, Biocompatible; Embolization, T | 2006 |
Early experience with Matrix detachable coils.
Topics: Coated Materials, Biocompatible; Embolization, Therapeutic; Follow-Up Studies; Humans; Intracranial | 2006 |
Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients.
Topics: Astrocytes; Brain; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; M | 2007 |
Lactate contents from cerebrospinal fluid in experimental subarachnoid hemorrhage, well correlate with vasospasm: ongoing and neurologic status.
Topics: Animals; Basilar Artery; Biomarkers; Cisterna Magna; Disease Models, Animal; Lactic Acid; Male; Nerv | 2007 |
Cerebral energy failure after subarachnoid hemorrhage: the role of relative hyperglycolysis.
Topics: Adult; Blood Pressure; Brain Diseases, Metabolic; Brain Ischemia; Cerebral Arteries; Cerebrovascular | 2007 |
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage.
Topics: Aged; Brain; Brain Ischemia; Female; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Intracr | 2007 |
Impact of hyperglycemia on neurological deficits and extracellular glucose levels in aneurysmal subarachnoid hemorrhage patients.
Topics: Adult; Blood Glucose; Brain; Energy Metabolism; Extracellular Fluid; Female; Glucose; Glycolysis; Hu | 2007 |
Use of ventricular cerebrospinal fluid lactate measurement to diagnose cerebrospinal fluid infection in patients with intraventricular haemorrhage.
Topics: Central Nervous System Infections; Humans; Lactic Acid; Prospective Studies; Subarachnoid Hemorrhage | 2008 |
Neurochemical monitoring and on-line pH measurements using brain microdialysis in patients in intensive care.
Topics: Acid-Base Equilibrium; Adult; Ascorbic Acid; Blood Glucose; Blood-Brain Barrier; Brain Edema; Brain | 1994 |
Long-term monitoring of CSF lactate levels and lactate/pyruvate ratios following subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Bicarbonates; Female; Humans; Hydrogen-Ion Concentration; Intracran | 1993 |
Early ischaemia after severe head injury. Preliminary results in patients with diffuse brain injuries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Brain; Brain Concussion; Brain Dama | 1993 |
Discrepancies between cerebral perfusion and metabolism after subarachnoid haemorrhage: a magnetic resonance approach.
Topics: Adult; Blood Volume; Brain Chemistry; Cerebrovascular Circulation; Feasibility Studies; Female; Hemo | 1998 |
Lactate and free fatty acids after subarachnoid hemorrhage.
Topics: Animals; Brain; Fatty Acids, Nonesterified; Lactic Acid; Male; Rats; Rats, Sprague-Dawley; Subarachn | 1999 |
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; Cerebral Cortex; Female; Glutamic Acid; Glyc | 1999 |
Clinical cerebral microdialysis: a methodological study.
Topics: Adult; Blood Glucose; Brain Chemistry; Brain Injuries; Catheters, Indwelling; Chromatography, High P | 2000 |
Multiple interstitial substances measured by microdialysis in patients with subarachnoid hemorrhage.
Topics: Acute Disease; Adult; Aged; Aneurysm, Ruptured; Biomarkers; Brain; Catecholamines; Cerebrospinal Flu | 2000 |
Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs.
Topics: Animals; Basilar Artery; Caspase Inhibitors; Caspases; Cerebrospinal Fluid; Disease Models, Animal; | 2001 |
Post-operative monitoring of cortical taurine in patients with subarachnoid hemorrhage: a microdialysis study.
Topics: Adult; Cerebral Cortex; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Monitoring, Physiologic; | 2000 |
Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes.
Topics: Brain; Brain Ischemia; Carbon Dioxide; Cerebral Angiography; Cerebral Infarction; Disabled Persons; | 2002 |
Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis.
Topics: Adult; Amino Acids; Craniocerebral Trauma; Critical Care; Dialysis; Female; Frontal Lobe; Humans; Hy | 1992 |
Time course of CSF lactate level in subarachnoid haemorrhage. Correlation with clinical grading and prognosis.
Topics: Acid-Base Equilibrium; Adult; Aged; Brain Edema; Brain Ischemia; Coma; Electrolytes; Female; Humans; | 1989 |