Page last updated: 2024-10-17

lactic acid and Skin Neoplasms

lactic acid has been researched along with Skin Neoplasms in 33 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
"A375 melanoma cancer cells were used for testing cellular entry and anticancer potentials of HMC and nano-7-hydroxy-6-methoxy coumarin (NHMC) through several standard protocols."7.76Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375. ( Bhattacharyya, SS; Boujedaini, N; Khuda-Bukhsh, AR; Paul, S, 2010)
"A375 melanoma cancer cells were used for testing cellular entry and anticancer potentials of HMC and nano-7-hydroxy-6-methoxy coumarin (NHMC) through several standard protocols."3.76Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375. ( Bhattacharyya, SS; Boujedaini, N; Khuda-Bukhsh, AR; Paul, S, 2010)
" Thirty-three patients underwent ILP with rhTNF alpha and melphalan for melanoma or soft-tissue sarcoma."3.69[O2 utilization during hyperthermic extremity perfusion with rhTNF alpha and melphalan]. ( Beck, K; Haier, J; Hohenberger, P; Schlag, PM, 1997)
"Melanoma is a malignant tumor in which UVA (320-400 nm) radiation is considered to be an important risk factor."2.53UVA-Irradiation Induces Melanoma Invasion via the Enhanced Warburg Effect. ( Baban, TSA; Bauer, J; Berneburg, M; Garbe, C; Kamenisch, Y; Metzler, G; Rocken, M; Schittek, B; Schuller, W; Sinnberg, T; von Thaler, AK, 2016)
"Cutaneous melanoma is an aggressive and deadly cancer resulting from malignant transformation of cells involved in skin pigmentation."1.91Glycolysis regulator PFKP induces human melanoma cell proliferation and tumor growth. ( Chen, C; Zhang, X, 2023)
"Melanoma is the most lethal of all skin-related cancers with incidences continuously rising."1.62In Vitro Evaluation of CD276-CAR NK-92 Functionality, Migration and Invasion Potential in the Presence of Immune Inhibitory Factors of the Tumor Microenvironment. ( Baden, C; Chan, KC; Grote, S; Handgretinger, R; Mezger, M; Schleicher, S; Ureña-Bailén, G, 2021)
"Melanoma is a largely incurable skin malignancy owing to the underlying molecular and metabolic heterogeneity confounded by the development of resistance."1.42Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression. ( Bhat, MK; Chaube, B; Malvi, P; Meena, AS; Mohammad, N; Singh, SV, 2015)
"Skin cancer is increasing at an alarming rate and becoming resistant to conventional chemotherapy necessitating improved drug delivery system."1.39Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: mitochondria mediated apoptotic signalling cascades. ( Das, J; Das, S; Khuda-Bukhsh, AR; Paul, A; Samadder, A, 2013)
"AIDS-related Kaposi's sarcoma (AIDS-KS), the most prevalent HIV-associated malignancy, is a debilitating, potentially fatal disease."1.31Sustained angiogenesis enables in vivo transplantation of mucocutaneous derived AIDS-related Kaposi's sarcoma cells in murine hosts. ( Kang, J; Mallery, SR; Ness, GM; Pei, P; Schwendeman, SP; Zhu, G, 2000)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's5 (15.15)18.2507
2000's5 (15.15)29.6817
2010's16 (48.48)24.3611
2020's5 (15.15)2.80

Authors

AuthorsStudies
Chen, C1
Zhang, X1
Feng, H1
Chen, W1
Zhang, C1
Wagner, M1
Ealey, KN1
Tetsu, H1
Kiniwa, T1
Motomura, Y1
Moro, K1
Koyasu, S1
Grote, S1
Ureña-Bailén, G1
Chan, KC1
Baden, C1
Mezger, M1
Handgretinger, R1
Schleicher, S1
Wang, Z2
Xu, F1
Hu, J1
Zhang, H3
Cui, L1
Lu, W1
He, W1
Wang, X3
Li, M1
Xiong, W1
Xie, C1
Liu, Y1
Zhou, P1
Liu, J1
Huang, P1
Qin, XF1
Xia, X1
Kamenisch, Y2
Ivanova, I1
Drexler, K1
Berneburg, M2
Das, S2
Das, J2
Samadder, A2
Paul, A2
Khuda-Bukhsh, AR3
Metivier, D1
Montravers, F1
Balogova, S1
Talbot, JN1
Guo, S1
Lin, CM1
Xu, Z1
Miao, L1
Wang, Y1
Huang, L1
Shi, L1
Tu, Q1
Wang, H1
Wang, P1
Zhang, L1
Huang, Z1
Zhao, F1
Luan, H1
Bhatnagar, P1
Pant, AB1
Shukla, Y1
Chaudhari, B1
Kumar, P1
Gupta, KC1
Li, J1
Krupka, T1
Yao, J1
Wang, R1
Jiang, L1
Zhou, Y1
Zuo, G1
Dai, L1
Ren, J1
Zheng, Y1
Wang, D1
Bruno, C1
Waeckerle-Men, Y1
Håkerud, M1
Kündig, TM1
Gander, B1
Johansen, P1
Chaube, B1
Malvi, P1
Singh, SV1
Mohammad, N1
Meena, AS1
Bhat, MK1
Baban, TSA1
Schuller, W1
von Thaler, AK1
Sinnberg, T1
Metzler, G1
Bauer, J1
Schittek, B1
Garbe, C1
Rocken, M1
Truchuelo, M1
Cerdá, P1
Fernández, LF1
Hersey, P1
Watts, RN1
Zhang, XD1
Hackett, J1
Bhattacharyya, SS1
Paul, S1
Boujedaini, N1
Scott, DA1
Richardson, AD1
Filipp, FV1
Knutzen, CA1
Chiang, GG1
Ronai, ZA1
Osterman, AL1
Smith, JW1
Farazuddin, M1
Sharma, B1
Khan, AA1
Joshi, B1
Owais, M1
Wadajkar, AS1
Bhavsar, Z1
Ko, CY1
Koppolu, B1
Cui, W1
Tang, L1
Nguyen, KT1
DEMOPOULOS, HB1
KALEY, G1
Bordel, MT1
Miranda, A1
Vincent, AS1
Phan, TT1
Mukhopadhyay, A1
Lim, HY1
Halliwell, B1
Wong, KP1
Häfeli, UO1
Sweeney, SM1
Beresford, BA1
Humm, JL1
Macklis, RM1
Solomon, BA1
Laude, TA1
Haier, J1
Hohenberger, P1
Beck, K1
Schlag, PM1
Artemov, D1
Bhujwalla, ZM1
Pilatus, U1
Glickson, JD1
Mallery, SR1
Pei, P1
Kang, J1
Zhu, G1
Ness, GM1
Schwendeman, SP1
Sabel, MS1
Hill, H1
Jong, YS1
Mathiowitz, E1
Bankert, RB1
Egilmez, NK1
Bernsen, HJ1
Heerschap, A1
van der Kogel, AJ1
van Vaals, JJ1
Prick, MJ1
Poels, EF1
Meyer, J1
Grotenhuis, JA1
Lyon, RC1
Tschudin, RG1
Daly, PF1
Cohen, JS1

Reviews

5 reviews available for lactic acid and Skin Neoplasms

ArticleYear
UVA, metabolism and melanoma: UVA makes melanoma hungry for metastasis.
    Experimental dermatology, 2018, Volume: 27, Issue:9

    Topics: Animals; Cell Survival; DNA Damage; Glucose; Glycolysis; Humans; Lactic Acid; Melanoma; Mitogen-Acti

2018
UVA-Irradiation Induces Melanoma Invasion via the Enhanced Warburg Effect.
    The Journal of investigative dermatology, 2016, Volume: 136, Issue:9

    Topics: Blood Glucose; Cell Line, Tumor; Follow-Up Studies; Humans; Lactic Acid; Melanoma; Melanoma, Cutaneo

2016
Chemical Peeling: A Useful Tool in the Office.
    Actas dermo-sifiliograficas, 2017, Volume: 108, Issue:4

    Topics: Acids; Animals; Chemexfoliation; Collagen Type I; Drug Combinations; Elastin; Epidermis; Ethanol; Fa

2017
Metabolic approaches to treatment of melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-01, Volume: 15, Issue:21

    Topics: Adenosine Triphosphate; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Melanoma; Metaboli

2009
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:2

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates;

1992

Other Studies

28 other studies available for lactic acid and Skin Neoplasms

ArticleYear
Glycolysis regulator PFKP induces human melanoma cell proliferation and tumor growth.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023, Volume: 25, Issue:7

    Topics: Adenosine Triphosphate; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Glycolysis; Humans; La

2023
Identification of lactylation gene CALML5 and its correlated lncRNAs in cutaneous melanoma by machine learning.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Calcium-Binding Proteins; Humans; Lactic Acid; Machine Learning; Melanoma; Melanoma, Cutaneous Malig

2023
Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s.
    Cell reports, 2020, 02-25, Volume: 30, Issue:8

    Topics: Animals; Cell Proliferation; Cell Survival; Eosinophils; Female; Humans; Immunity, Innate; Interleuk

2020
In Vitro Evaluation of CD276-CAR NK-92 Functionality, Migration and Invasion Potential in the Presence of Immune Inhibitory Factors of the Tumor Microenvironment.
    Cells, 2021, 04-26, Volume: 10, Issue:5

    Topics: Antigens, Neoplasm; B7 Antigens; Cell Line, Tumor; Cell Movement; CRISPR-Cas Systems; Cytotoxicity,

2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
    Journal for immunotherapy of cancer, 2021, Volume: 9, Issue:5

    Topics: Animals; Antineoplastic Agents; Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Clotri

2021
Strategic formulation of apigenin-loaded PLGA nanoparticles for intracellular trafficking, DNA targeting and improved therapeutic effects in skin melanoma in vitro.
    Toxicology letters, 2013, Nov-25, Volume: 223, Issue:2

    Topics: Apigenin; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3;

2013
Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: mitochondria mediated apoptotic signalling cascades.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Animals; Anticarcinogenic Agents; Apigenin; Apoptosis; Benzo(a)pyrene; Drug Carriers; Lactic Acid; M

2013
18F-FDG PET/CT uptake due to poly-L-lactic acid facial injections.
    Nuklearmedizin. Nuclear medicine, 2013, Dec-13, Volume: 52, Issue:6

    Topics: Aged; Diagnosis, Differential; Facial Dermatoses; False Positive Reactions; Fluorodeoxyglucose F18;

2013
Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation.
    ACS nano, 2014, May-27, Volume: 8, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chromatography, High Pressure Liquid; C

2014
Treating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Lactic Acid; Mice; Mice, Hairless; Nanoparti

2015
Bromelain nanoparticles protect against 7,12-dimethylbenz[a]anthracene induced skin carcinogenesis in mouse model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 91

    Topics: Administration, Cutaneous; Ananas; Animals; Anticarcinogenic Agents; Bromelains; Carcinogenesis; Del

2015
Liquid-solid phase-inversion PLGA implant for the treatment of residual tumor tissue after HIFU ablation.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Doxorubicin; Drug Carri

2015
Photosensitizer and Light Pave the Way for Cytosolic Targeting and Generation of Cytosolic CD8 T Cells Using PLGA Vaccine Particles.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Jul-01, Volume: 195, Issue:1

    Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cancer Vaccines; Cytosol; Dendritic Cells; Drug C

2015
Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Lin

2015
Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375.
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2010, Volume: 8, Issue:9

    Topics: Apoptosis; Caspase 3; Coumarins; Down-Regulation; Humans; Imidazoles; Lactic Acid; Melanoma; Nanopar

2010
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.
    The Journal of biological chemistry, 2011, Dec-09, Volume: 286, Issue:49

    Topics: Cell Line, Tumor; Citric Acid Cycle; Fermentation; Gas Chromatography-Mass Spectrometry; Glucose; Gl

2011
Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell

2012
Multifunctional particles for melanoma-targeted drug delivery.
    Acta biomaterialia, 2012, Volume: 8, Issue:8

    Topics: Acrylic Resins; Animals; Cell Death; Drug Delivery Systems; Fibroblasts; Humans; Hydrodynamics; Lact

2012
Selective inhibition of respiration of pigmented S91 mouse melanomas by phenyl lactate, and the possibly related effects on growth.
    Journal of the National Cancer Institute, 1963, Volume: 30

    Topics: Animals; Antimetabolites; Lactates; Lactic Acid; Melanoma; Mice; Skin Neoplasms

1963
[Unilateral nevus comedonicus: efficacy after treatment with 12% ammonium lactate].
    Actas dermo-sifiliograficas, 2006, Volume: 97, Issue:2

    Topics: Dermatologic Agents; Female; Humans; Lactic Acid; Middle Aged; Nevus, Pigmented; Quaternary Ammonium

2006
Human skin keloid fibroblasts display bioenergetics of cancer cells.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:3

    Topics: Adenosine Triphosphate; Adolescent; Adult; Antimutagenic Agents; Cell Hypoxia; Cells, Cultured; Chil

2008
Effective targeting of magnetic radioactive 90Y-microspheres to tumor cells by an externally applied magnetic field. Preliminary in vitro and in vivo results.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:2

    Topics: Animals; Cell Line; Cell Survival; Culture Techniques; Dose-Response Relationship, Radiation; Female

1995
Two patients with confluent and reticulated papillomatosis: response to oral isotretinoin and 10% lactic acid lotion.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Dermatologic Agents; Emollients; Female

1996
[O2 utilization during hyperthermic extremity perfusion with rhTNF alpha and melphalan].
    Langenbecks Archiv fur Chirurgie, 1997, Volume: 382, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Carbon Dioxide; Chemotherapy, Cancer, Re

1997
Two-compartment model for determination of glycolytic rates of solid tumors by in vivo 13C NMR spectroscopy.
    NMR in biomedicine, 1998, Volume: 11, Issue:8

    Topics: Animals; Carbon Isotopes; Disease Models, Animal; Female; Fibrosarcoma; Glucose; Glycolysis; Lactic

1998
Sustained angiogenesis enables in vivo transplantation of mucocutaneous derived AIDS-related Kaposi's sarcoma cells in murine hosts.
    Carcinogenesis, 2000, Volume: 21, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Animals; Cattle; Delayed-Action Preparations; Disease Models, An

2000
Neoadjuvant therapy with interleukin-12-loaded polylactic acid microspheres reduces local recurrence and distant metastases.
    Surgery, 2001, Volume: 130, Issue:3

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Immunity; Injections, Intralesional; Interleukin-12

2001
A versatile multinuclear probe designed for in vivo NMR spectroscopy: applications to subcutaneous human tumors in mice.
    Magnetic resonance in medicine, 1988, Volume: 6, Issue:1

    Topics: Animals; Breast Neoplasms; Colonic Neoplasms; Glucose; Humans; In Vitro Techniques; Infant, Newborn;

1988