lactic acid has been researched along with Shock in 141 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The severity of lactic acidosis in critically ill patients correlates with overall oxygen debt and survival." | 8.78 | Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992) |
| "Background Lactic acidosis is associated with mortality in patients with cardiogenic shock (CS)." | 8.12 | Association Between the Acidemia, Lactic Acidosis, and Shock Severity With Outcomes in Patients With Cardiogenic Shock. ( Barsness, GW; Blankenberg, S; Holmes, DR; Jentzer, JC; Kashani, KB; Kirchhof, P; Patel, PC; Schrage, B; Westermann, D, 2022) |
| "To evaluate the value of blood lactic acid (BLA) as a predictor for the severity and prognosis of neonatal shock." | 7.88 | [Value of arterial blood lactic acid in the evaluation of disease severity and prognosis in neonatal shock]. ( Cai, BH; Huang, YP; Liu, HC; Liu, XY; Wang, QL; Wang, S; Yuan, WH; Zeng, LK; Zhao, LX, 2018) |
| " Animals, under urethane anesthesia, were exposed to high ambient temperature of 42 degrees C until mean arterial pressure and local cerebral blood flow in the striatum began to decrease, which was arbitrarily defined as the onset of heatstroke." | 7.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "Dopexamine protects colonic, but not gastric mucosal epithelium in experimental endotoxin shock." | 7.72 | Dopexamine reverses colonic but not gastric mucosal perfusion defects in lethal endotoxin shock. ( Martikainen, TJ; Ruokonen, E; Tenhunen, JJ; Uusaro, A, 2003) |
| "The hyperproteinemia was attributed to dehydration, the lactic acidemia to shock, and the hyperphosphatemia to acidosis and transient renal failure." | 5.27 | The acidosis of cholera. Contributions of hyperproteinemia, lactic acidemia, and hyperphosphatemia to an increased serum anion gap. ( Butler, T; Jones, PK; Rabbani, GH; Wang, F, 1986) |
| "To investigate the effects of dietary supplementation of l-arginine (l-Arg) on shock in severely burned patients." | 5.12 | Effects of early enteral arginine supplementation on resuscitation of severe burn patients. ( Huang, Y; Li, F; Peng, X; Wang, P; Yan, H; Zhao, M, 2007) |
| "Metformin poisoning with lactic acidosis appears to be amenable to extracorporeal treatments." | 4.91 | Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup. ( Calello, DP; Ghannoum, M; Gosselin, S; Hoffman, RS; Lavergne, V; Liu, KD; Nolin, TD; Roberts, DM; Wiegand, TJ, 2015) |
| "The severity of lactic acidosis in critically ill patients correlates with overall oxygen debt and survival." | 4.78 | Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992) |
| "Background Lactic acidosis is associated with mortality in patients with cardiogenic shock (CS)." | 4.12 | Association Between the Acidemia, Lactic Acidosis, and Shock Severity With Outcomes in Patients With Cardiogenic Shock. ( Barsness, GW; Blankenberg, S; Holmes, DR; Jentzer, JC; Kashani, KB; Kirchhof, P; Patel, PC; Schrage, B; Westermann, D, 2022) |
| " Emergency physicians may consider the development of hypotension, high creatine, lactate, base excess, low bicarbonate, and blood pH to be associated with a poor prognosis in the first hours of admission in acute poisoning patients." | 4.12 | Prospective analysis of intoxicated patients developing shock and/or organ failure. ( Akday, U; Akpınar, AA; Dişel, NR; Karakoç, E; Taşkın, Ö; Tekin, F, 2022) |
| "Bosutinib as an adjunct therapy to a balanced transfusion strategy reduced resuscitation volume, improved shock reversal, and reduced vascular leak and organ injury in a rat polytrauma model." | 4.02 | Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model. ( Aman, J; Botros, L; Hollmann, MW; Juffermans, NP; Kers, J; Kleinveld, DJB; Maas, MAW, 2021) |
| "To evaluate the value of blood lactic acid (BLA) as a predictor for the severity and prognosis of neonatal shock." | 3.88 | [Value of arterial blood lactic acid in the evaluation of disease severity and prognosis in neonatal shock]. ( Cai, BH; Huang, YP; Liu, HC; Liu, XY; Wang, QL; Wang, S; Yuan, WH; Zeng, LK; Zhao, LX, 2018) |
| "In this study, blood redox potential (ORP) values (ΔORP value was adopted, as the quantitative index to reflect the overall redox status), plasma uric acid levels (important antioxidant, as antioxidant index), and the burn shock state-related indicators (lactic acid and hematocrit) of 48 burn patients were dynamically, quantitatively monitored during the early stage after injury." | 3.81 | The characteristics and correlation between the ischemia-reperfusion and changes of redox status in the early stage of severe burns. ( Han, C; Hu, H; Hu, X; Pan, X; Shao, H; Xu, J; Yu, C; Zhi, L, 2015) |
| " Other metabolic abnormalities, including hypernatremia, hyponatremia, low ionized calcium and magnesium levels, and lactic acidosis may contribute to muscle fatigue and collapse." | 3.74 | Cardiac biomarkers, electrolytes, and other analytes in collapsed marathon runners: implications for the evaluation of runners following competition. ( Januzzi, J; Lee-Lewandrowski, E; Lewandrowski, KB; Shirey, T; Siegel, AJ; Sluss, P; Wood, M, 2008) |
| " Animals, under urethane anesthesia, were exposed to high ambient temperature of 42 degrees C until mean arterial pressure and local cerebral blood flow in the striatum began to decrease, which was arbitrarily defined as the onset of heatstroke." | 3.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "Dopexamine protects colonic, but not gastric mucosal epithelium in experimental endotoxin shock." | 3.72 | Dopexamine reverses colonic but not gastric mucosal perfusion defects in lethal endotoxin shock. ( Martikainen, TJ; Ruokonen, E; Tenhunen, JJ; Uusaro, A, 2003) |
| "05) protected from lactic acidosis, glutamate buildup, and diminished HCO(3)(-) levels." | 3.71 | CD8(+)-T-cell depletion ameliorates circulatory shock in Plasmodium berghei-infected mice. ( Chang, WL; Granger, DN; Huang, J; Jones, SP; Lefer, DJ; Sun, G; Suzuki, H; van der Heyde, HC; Welbourne, T; Yin, L, 2001) |
| " Hyperlactatemia with L/P ratio elevation and lactic acidosis is likely to be associated with inadequate tissue perfusion." | 3.70 | Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions. ( Kari, A; Ruokonen, E; Suistomaa, M; Takala, J, 2000) |
| " In addition, all tyrphostins and genistein attenuated the liver injury/failure, the pancreatic injury, the hypoglycaemia and the lactic acidosis caused by LPS." | 3.69 | Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase. ( Ruetten, H; Thiemermann, C, 1997) |
| " Despite this there is still controversy about the most appropriate therapy of lactic acidosis, and the relationship of commonly used acid base measurements to blood lactate levels." | 3.68 | Lactate and acid base changes in the critically ill. ( Grant, IS; Mackenzie, SJ; Nimmo, GR, 1991) |
| "A study was done to measure beta-endorphin immunoreactivity (beta-EI) in swine subjected to cardiopulmonary bypass at normal aortic perfusion pressures and during low-flow states such as can occur with shock." | 3.67 | Naloxone: ineffective in improving cardiac performance after hypoperfusion in swine. ( Bellamy, RF; Heydorn, WH; Moores, WY; O'Benar, JD, 1985) |
| " A third patient, diabetic and under treatment with phenformin hydrochloride, presented with many features suggestive of pulmonary embolism, including marked pulmonary hypertension." | 3.64 | THE CLINICAL SIGNIFICANCE OF ELEVATED BLOOD LACTATE. ( PHILLIPSON, EA; SPROULE, BJ, 1965) |
| "Shock is a sequelae in trauma and burn patients that substantially increases the risk for morbidity and mortality." | 2.82 | Utilization and Efficacy of Resuscitation Endpoints in Trauma and Burn Patients: A Review Article. ( Ali, A; Belaunzaran, M; Elkbuli, A; McKenney, M; Newsome, K; Raslan, S, 2022) |
| "Resuscitation is the process of treating shock in an attempt to restore normal physiology." | 2.52 | Endpoints in resuscitation. ( Connelly, CR; Schreiber, MA, 2015) |
| "Circulatory shock is a syndrome characterized by imbalance between oxygen supply and demand." | 2.38 | Pathophysiology and treatment of circulatory shock. ( Astiz, ME; Rackow, EC; Weil, MH, 1993) |
| "Children having septic shock aged from 3 to 60 months were studied within the first 24 hours of admission." | 1.72 | Evaluation of Venous-to-Arterial Carbon Dioxide Tension Difference as a Complementary Parameter During Pediatric Septic Shock Resuscitation: A Prospective Observational Study. ( El-Nawawy, AA; Hassaan, SM; Hassouna, HM, 2022) |
| "Pediatric shock was categorized either: compensated with normal blood pressure, poor skin perfusion (CRT >2 s, mottled, cool peripheries, peripheral cyanosis), weak peripheral pulse, age specific tachycardia, tachypnoea, and oliguria or decompensated with hypotension (SBP < 70 + (2× age in years) mm Hg and decreased mental status." | 1.62 | Assessment of Tissue Perfusion Using the Peripheral Perfusion Index and Lactate Clearance in Shock in Pediatric Patients. ( Algebaly, H; Bazaraa, H; Roby, S; Salah, E, 2021) |
| "Shock was defined as abnormalities in ≥3 of the 6 following criteria: HR > 120/min, RR > 40/min, CRT > 2 seconds, rectal temperature <37." | 1.56 | Evaluation of the rectal-interdigital temperature gradient as a diagnostic marker of shock in dogs. ( Drobatz, KJ; Reineke, EL; Reminga, CL; Schaefer, JD, 2020) |
| "Hypovolemia was induced and maintained for 20 min by removal of 50% of the total blood volume; thereafter, the animals were retransfused." | 1.56 | Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model. ( Bischoff, SJ; Irintchev, A; Lehmann, T; Lemke, C; Nistor, M; Schiffner, R; Schmidt, M, 2020) |
| " Lactate dosage was performed at ED-HDU admission (T0), after 2 h (T2), 6 h (T6) and 24 h (T24); lactate clearance was calculated at T2 and T6 [T2: ((LAC T0-LAC T2/LAC T0)*100)]; T6: [(LAC T0-LAC T6/LAC T0)*100]." | 1.51 | Prognostic value of serial lactate levels in septic patients with and without shock. ( Caldi, F; Donnini, C; Giacomelli, I; Innocenti, F; Meo, F; Pini, R; Ralli, ML; Tassinari, I; Tozzi, C; Zanobetti, M, 2019) |
| "Among 314 normotensive trauma patients, the area under the receiver operator characteristic curve for PLac predicting need for RC was 0." | 1.48 | Prehospital Lactate Predicts Need for Resuscitative Care in Non-hypotensive Trauma Patients. ( Bulger, EM; Guyette, FX; McCoy, AM; Moyes, AG; Sayre, MR; St John, AE, 2018) |
| "It has higher predictive efficacy in septic shock, especially for 28-day prognosis." | 1.46 | Clinical study of a new Modified Early Warning System scoring system for rapidly evaluating shock in adults. ( Cao, Y; Qin, Q; Xia, Y, 2017) |
| "Lactic acidosis was fully corrected and survival increased in group PR (50." | 1.43 | Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs. ( Bai, XD; Guo, SJ; Hu, S; Hu, XH; Li, ZY; Liu, R; Wang, SM; Zhou, FQ, 2016) |
| "Circulatory failure is frequent in intensive care unit (ICU) patients and is associated with a high mortality and morbidity." | 1.39 | Variable assessment of the circulation in intensive care unit patients with shock. ( Haase, N; Hennings, LI; Perner, A, 2013) |
| "We selected trauma patients admitted to a level I trauma center over a 9-year period with SBP between 90 and 110 mmHg." | 1.36 | Lactate is a better predictor than systolic blood pressure for determining blood requirement and mortality: could prehospital measures improve trauma triage? ( Griffin, RL; Kerby, JD; Rue, LW; Vandromme, MJ; Weinberg, JA, 2010) |
| "During septic shock, muscle produces lactate by way of an exaggerated NaK-adenosine triphosphatase (ATPase)-stimulated aerobic glycolysis associated with epinephrine stimulation possibly through beta2 adrenoreceptor involvement." | 1.35 | Increased aerobic glycolysis through beta2 stimulation is a common mechanism involved in lactate formation during shock states. ( Desebbe, O; Gibot, S; Levy, B; Montemont, C, 2008) |
| "Shock was more frequently present in the low [BE] group (46% versus 24%, P = 0." | 1.35 | Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches. ( Dubin, A; Kutscherauer, DO; Masevicius, FD; Pein, MC; Tuhay, G, 2008) |
| "During hypovolemic shock, the lactate production increased and the glucose concentration decreased or remained normal." | 1.34 | Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock. ( Alhava, E; Härmä, M; Joukainen, S; Setälä, L; Uusaro, A, 2007) |
| "Twenty-one patients had severe sepsis or septic shock." | 1.32 | Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients. ( Bankov, A; Marik, PE, 2003) |
| "During endotoxin shock mean arterial pressure (MAP) and cardiac output (CO) fall, and the latter is redistributed." | 1.29 | The fall of cardiac output in endotoxemic rats cannot explain all changes in organ blood flow: a comparison between endotoxin and low venous return shock. ( Mulder, MF; Thijs, LG; van den Bos, GC; van Lambalgen, AA, 1996) |
| "Shock is defined as the summation of cellular dysfunction and resultant impairment of the function in various organs." | 1.28 | [Cellular metabolic consideration in the pathophysiology and the treatment of shock]. ( Hirasawa, H; Oda, S; Otake, Y; Shiga, H; Sugai, T, 1989) |
| "Nineteen patients had nonseptic shock (NSS), and 31 had septic shock (SS)." | 1.27 | Relation of arterial blood lactate to oxygen delivery and hemodynamic variables in human shock states. ( Groeneveld, AB; Kester, AD; Nauta, JJ; Thijs, LG, 1987) |
| "The hyperproteinemia was attributed to dehydration, the lactic acidemia to shock, and the hyperphosphatemia to acidosis and transient renal failure." | 1.27 | The acidosis of cholera. Contributions of hyperproteinemia, lactic acidemia, and hyperphosphatemia to an increased serum anion gap. ( Butler, T; Jones, PK; Rabbani, GH; Wang, F, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (19.15) | 18.7374 |
| 1990's | 14 (9.93) | 18.2507 |
| 2000's | 33 (23.40) | 29.6817 |
| 2010's | 47 (33.33) | 24.3611 |
| 2020's | 20 (14.18) | 2.80 |
| Authors | Studies |
|---|---|
| Belaunzaran, M | 1 |
| Raslan, S | 1 |
| Ali, A | 1 |
| Newsome, K | 1 |
| McKenney, M | 1 |
| Elkbuli, A | 1 |
| El-Nawawy, AA | 1 |
| Hassaan, SM | 1 |
| Hassouna, HM | 1 |
| Özakın, E | 2 |
| Özcan Yazlamaz, N | 1 |
| Baloğlu Kaya, F | 1 |
| Çanakçı, ME | 1 |
| Bilgin, M | 1 |
| Jentzer, JC | 2 |
| Schrage, B | 1 |
| Patel, PC | 1 |
| Kashani, KB | 1 |
| Barsness, GW | 2 |
| Holmes, DR | 1 |
| Blankenberg, S | 1 |
| Kirchhof, P | 1 |
| Westermann, D | 1 |
| Tekin, F | 3 |
| Akpınar, AA | 3 |
| Taşkın, Ö | 3 |
| Akday, U | 3 |
| Dişel, NR | 3 |
| Karakoç, E | 3 |
| Lundin, A | 1 |
| Annborn, M | 1 |
| Borgquist, O | 1 |
| Düring, J | 1 |
| Undén, J | 1 |
| Rylander, C | 1 |
| Yuniar, I | 1 |
| Fitriasari, R | 1 |
| Prawira, Y | 1 |
| Handryastuti, S | 1 |
| Kadim, M | 1 |
| Triratna, S | 1 |
| Djer, MM | 1 |
| Wernly, B | 1 |
| Bakker, J | 5 |
| Jung, C | 1 |
| Innocenti, F | 1 |
| Meo, F | 1 |
| Giacomelli, I | 1 |
| Tozzi, C | 1 |
| Ralli, ML | 1 |
| Donnini, C | 1 |
| Tassinari, I | 1 |
| Caldi, F | 1 |
| Zanobetti, M | 1 |
| Pini, R | 1 |
| Schiffner, R | 1 |
| Bischoff, SJ | 1 |
| Lehmann, T | 1 |
| Irintchev, A | 1 |
| Nistor, M | 1 |
| Lemke, C | 1 |
| Schmidt, M | 1 |
| Burstein, B | 1 |
| Vallabhajosyula, S | 1 |
| Ternus, B | 1 |
| Kashani, K | 1 |
| Daurat, A | 1 |
| Dick, M | 1 |
| Louart, B | 1 |
| Lefrant, JY | 1 |
| Muller, L | 1 |
| Roger, C | 1 |
| Kramer, A | 1 |
| Al Agha, S | 1 |
| Böhm, L | 1 |
| Michael, M | 1 |
| Schulze-Bosse, K | 1 |
| Bernhard, M | 1 |
| Schaefer, JD | 1 |
| Reminga, CL | 1 |
| Reineke, EL | 2 |
| Drobatz, KJ | 2 |
| Davis, JW | 3 |
| Sue, LP | 1 |
| Dirks, RC | 2 |
| Kaups, KL | 2 |
| Kwok, AM | 1 |
| Wolfe, MM | 1 |
| Lilienstein, JT | 1 |
| Bilello, JF | 1 |
| Kleinveld, DJB | 1 |
| Botros, L | 1 |
| Maas, MAW | 1 |
| Kers, J | 1 |
| Aman, J | 1 |
| Hollmann, MW | 1 |
| Juffermans, NP | 1 |
| Keville, MP | 1 |
| Gelmann, D | 1 |
| Hollis, G | 1 |
| Beher, R | 1 |
| Raffman, A | 1 |
| Tanveer, S | 1 |
| Jones, K | 1 |
| Parker, BM | 1 |
| Haase, DJ | 1 |
| Tran, QK | 1 |
| Cetinkaya, HB | 1 |
| Gunes, H | 1 |
| Dror, N | 1 |
| Weidling, J | 1 |
| White, S | 1 |
| Ortenzio, F | 1 |
| Shreim, S | 1 |
| Keating, MT | 1 |
| Pham, H | 1 |
| Radom-Aizik, S | 1 |
| Botvinick, E | 1 |
| Bazaraa, H | 1 |
| Roby, S | 1 |
| Salah, E | 1 |
| Algebaly, H | 1 |
| Borgel, D | 1 |
| Chocron, R | 1 |
| Grimaud, M | 1 |
| Philippe, A | 1 |
| Chareyre, J | 1 |
| Brakta, C | 1 |
| Lasne, D | 1 |
| Bonnet, D | 1 |
| Toubiana, J | 1 |
| Angoulvant, F | 1 |
| Desvages, M | 1 |
| Renolleau, S | 1 |
| Smadja, DM | 1 |
| Oualha, M | 1 |
| Kiyatkin, ME | 1 |
| Yacoub, S | 1 |
| Trung, TH | 1 |
| Lam, PK | 1 |
| Thien, VHN | 1 |
| Hai, DHT | 1 |
| Phan, TQ | 1 |
| Nguyet, OPK | 1 |
| Quyen, NTH | 1 |
| Simmons, CP | 1 |
| Broyd, C | 1 |
| Screaton, GR | 1 |
| Wills, B | 1 |
| Lu, Z | 1 |
| Wang, X | 1 |
| Yang, J | 1 |
| Li, S | 1 |
| Yan, J | 1 |
| Londoño, J | 1 |
| Niño, C | 1 |
| Díaz, J | 1 |
| Morales, C | 1 |
| León, J | 1 |
| Bernal, E | 1 |
| Vargas, C | 1 |
| Mejía, L | 1 |
| Hincapié, C | 1 |
| Ascuntar, J | 1 |
| León, A | 1 |
| Jaimes, F | 1 |
| Huang, M | 1 |
| Chen, JF | 1 |
| Chen, LY | 1 |
| Pan, LQ | 1 |
| Li, XJ | 1 |
| Ye, JY | 1 |
| Tan, HY | 1 |
| De Backer, D | 3 |
| Yuan, WH | 1 |
| Zeng, LK | 1 |
| Cai, BH | 1 |
| Liu, XY | 1 |
| Wang, S | 1 |
| Zhao, LX | 1 |
| Huang, YP | 1 |
| Wang, QL | 1 |
| Liu, HC | 1 |
| Tran, P | 1 |
| St John, AE | 1 |
| McCoy, AM | 1 |
| Moyes, AG | 1 |
| Guyette, FX | 1 |
| Bulger, EM | 1 |
| Sayre, MR | 1 |
| Gilje, P | 1 |
| Frydland, M | 1 |
| Bro-Jeppesen, J | 1 |
| Dankiewicz, J | 1 |
| Friberg, H | 1 |
| Rundgren, M | 1 |
| Devaux, Y | 1 |
| Stammet, P | 1 |
| Al-Mashat, M | 1 |
| Jögi, J | 1 |
| Kjaergaard, J | 1 |
| Hassager, C | 1 |
| Erlinge, D | 1 |
| Sohn, CH | 1 |
| Kim, YJ | 1 |
| Seo, DW | 1 |
| Won, HS | 1 |
| Shim, JY | 1 |
| Lim, KS | 1 |
| Kim, WY | 1 |
| Hoehn, MR | 1 |
| Teeter, WA | 1 |
| Morrison, JJ | 1 |
| Gamble, WB | 1 |
| Hu, P | 1 |
| Stein, DM | 1 |
| Brenner, ML | 1 |
| Scalea, TM | 2 |
| Hallisey, SD | 1 |
| Greenwood, JC | 1 |
| Monnet, X | 2 |
| Julien, F | 1 |
| Ait-Hamou, N | 1 |
| Lequoy, M | 1 |
| Gosset, C | 1 |
| Jozwiak, M | 1 |
| Persichini, R | 1 |
| Anguel, N | 1 |
| Richard, C | 1 |
| Teboul, JL | 1 |
| Hennings, LI | 1 |
| Haase, N | 1 |
| Perner, A | 1 |
| Ducrocq, N | 1 |
| Kimmoun, A | 1 |
| Levy, B | 4 |
| Andersen, LW | 1 |
| Mackenhauer, J | 1 |
| Roberts, JC | 1 |
| Berg, KM | 1 |
| Cocchi, MN | 1 |
| Donnino, MW | 1 |
| Vincent, JL | 1 |
| Cevik, AA | 1 |
| Dolgun, H | 1 |
| Oner, S | 1 |
| Tokar, B | 1 |
| Acar, N | 1 |
| Kaya, F | 1 |
| Zhi, L | 1 |
| Hu, X | 1 |
| Xu, J | 1 |
| Yu, C | 1 |
| Shao, H | 1 |
| Pan, X | 1 |
| Hu, H | 1 |
| Han, C | 1 |
| Sonobe, T | 1 |
| Haouzi, P | 1 |
| Calello, DP | 1 |
| Liu, KD | 1 |
| Wiegand, TJ | 1 |
| Roberts, DM | 1 |
| Lavergne, V | 1 |
| Gosselin, S | 1 |
| Hoffman, RS | 1 |
| Nolin, TD | 1 |
| Ghannoum, M | 1 |
| Rees, C | 1 |
| Connelly, CR | 1 |
| Schreiber, MA | 2 |
| Delaney, A | 1 |
| Barnato, A | 1 |
| Bloos, F | 1 |
| Zhang, Z | 1 |
| Boulain, T | 1 |
| Hernandez, G | 1 |
| Arslan, A | 1 |
| Flax, L | 1 |
| Fraser, R | 1 |
| Kanter, M | 1 |
| Simon, R | 1 |
| Caputo, ND | 1 |
| Liu, R | 1 |
| Hu, XH | 1 |
| Wang, SM | 1 |
| Guo, SJ | 1 |
| Li, ZY | 1 |
| Bai, XD | 1 |
| Zhou, FQ | 1 |
| Hu, S | 1 |
| Zhang, C | 1 |
| Zhang, J | 1 |
| Zhang, D | 1 |
| Xie, W | 1 |
| Jiang, Z | 1 |
| Lin, G | 1 |
| Niu, X | 1 |
| Huang, Y | 2 |
| Goyal, N | 1 |
| Taylor, AR | 1 |
| Rivers, EP | 2 |
| Kaths, JM | 1 |
| Echeverri, J | 1 |
| Chun, YM | 1 |
| Cen, JY | 1 |
| Goldaracena, N | 1 |
| Linares, I | 1 |
| Dingwell, LS | 1 |
| Yip, PM | 1 |
| John, R | 1 |
| Bagli, D | 1 |
| Mucsi, I | 1 |
| Ghanekar, A | 1 |
| Grant, DR | 1 |
| Robinson, LA | 1 |
| Selzner, M | 1 |
| Qin, Q | 1 |
| Xia, Y | 1 |
| Cao, Y | 1 |
| van den Nouland, DP | 1 |
| Brouwers, MC | 1 |
| Stassen, PM | 1 |
| Knobloch, K | 1 |
| Gohritz, A | 1 |
| Vogt, P | 1 |
| Pearse, RM | 1 |
| Neff, LP | 1 |
| Allman, JM | 1 |
| Holmes, JH | 1 |
| van Beest, PA | 1 |
| Mulder, PJ | 1 |
| Oetomo, SB | 1 |
| van den Broek, B | 1 |
| Kuiper, MA | 1 |
| Spronk, PE | 1 |
| Strehlow, MC | 1 |
| Wutrich, Y | 1 |
| Barraud, D | 1 |
| Conrad, M | 1 |
| Cravoisy-Popovic, A | 1 |
| Nace, L | 1 |
| Bollaert, PE | 1 |
| Gibot, S | 2 |
| Vandromme, MJ | 1 |
| Griffin, RL | 1 |
| Weinberg, JA | 1 |
| Rue, LW | 1 |
| Kerby, JD | 1 |
| Hobbs, TR | 1 |
| O'Malley, JP | 1 |
| Khouangsathiene, S | 1 |
| Dubay, CJ | 1 |
| Schumer, W | 1 |
| Visser, M | 1 |
| Vermeulen, MA | 1 |
| Richir, MC | 1 |
| Teerlink, T | 1 |
| Houdijk, AP | 1 |
| Kostense, PJ | 1 |
| Wisselink, W | 1 |
| de Mol, BA | 1 |
| van Leeuwen, PA | 1 |
| Oudemans-van Straaten, HM | 1 |
| Eddleston, M | 1 |
| Street, JM | 1 |
| Self, I | 1 |
| Thompson, A | 1 |
| King, T | 1 |
| Williams, N | 1 |
| Naredo, G | 1 |
| Dissanayake, K | 1 |
| Yu, LM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Ability of Peripheral Perfusion Index To Detect Changes of Hemodynamics in Patients With Pacemaker：a Prospective Study[NCT04952649] | 50 participants (Anticipated) | Observational | 2021-07-07 | Recruiting | |||
| Descriptive and Retrospective Analysis of Acute Myocarditis Associated With Pandemic COVID-19 in Children[NCT04420468] | 30 participants (Anticipated) | Observational | 2020-06-10 | Recruiting | |||
| Exploratory Study. Endothelial Function and Vascular Biomarkers: Predictive Indicators of the Progression From Gestational Hypertension to Preeclampsia?[NCT04520048] | 110 participants (Anticipated) | Interventional | 2023-08-24 | Recruiting | |||
| Characteristics of Patients With Severe Dengue Admitted in Critical Care Units at Villavicencio, Colombia. A Retrospective Observational Trial.[NCT05938647] | 50 participants (Anticipated) | Observational | 2023-07-01 | Recruiting | |||
| The Effect of Intra Aortic Balloon Pump Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary Syndrome[NCT03638609] | 102 participants (Anticipated) | Interventional | 2017-10-23 | Recruiting | |||
| The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies[NCT05145049] | 110 participants (Actual) | Observational [Patient Registry] | 2021-11-01 | Completed | |||
| The Effects of Intra Aortic Balloon Pump Prior to Revascularization on Mortality of Patients With Acute Coronary Syndrome Complicated With Cardiogenic Shock[NCT03635840] | 92 participants (Anticipated) | Interventional | 2018-01-04 | Recruiting | |||
| A Randomized Controlled Trial of Crystalloid Alone Versus Crystalloid Plus Colloid in Shock Resuscitation[NCT02782819] | 320 participants (Anticipated) | Interventional | 2014-09-30 | Recruiting | |||
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock: a Randomized Clinical Study (VITAMIN TRIAL)[NCT05192213] | Phase 3 | 1,090 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | ||
| Critical Care Ultrasound Oriented Shock Treatment in ICU[NCT03093987] | 150 participants (Actual) | Interventional | 2017-04-05 | Completed | |||
| Early Goal Directed Therapy Using a Physiological Holistic View. A Multicenter Study in Latin America: The ANDROMEDA-SHOCK Study[NCT03078712] | 424 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Hemodynamic Resuscitation and Monitoring in Early Sepsis[NCT04143035] | 500 participants (Anticipated) | Observational | 2019-10-22 | Active, not recruiting | |||
| Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients: Pathophysiological Determinants, and Relation to Changes in Systemic, Regional and Microcirculatory Blood Flow[NCT04693923] | 42 participants (Anticipated) | Interventional | 2021-02-01 | Not yet recruiting | |||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| Feasibility of Lactate Level Evaluation in Prehospital Care in Trauma[NCT03115970] | 30 participants (Anticipated) | Observational [Patient Registry] | 2017-05-01 | Not yet recruiting | |||
| A Multi-center, Multinational, Randomized, Double-blind, Controlled, Dose Comparison Study to Evaluate Safety and Efficacy of MP4OX Plus Standard Treatment, in Severely Injured Trauma Subjects With Lactic Acidosis Due to Hemorrhagic Shock[NCT01973504] | Phase 2 | 0 participants (Actual) | Interventional | 2013-12-31 | Withdrawn (stopped due to Sangart ceased operations) | ||
| Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)[NCT02742974] | 196 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit[NCT01624519] | 50 participants (Anticipated) | Interventional | 2012-08-31 | Not yet recruiting | |||
| Resuscitation Failure, Protein Carbonyl and Receptor Interacting Protein Kinase 3 as Mortality Predictor in Septic Patient[NCT04169412] | 72 participants (Actual) | Observational [Patient Registry] | 2019-02-22 | Completed | |||
| "Influence of High Vitamin C Dose on Lactate During Extracorporeal Circulation for Heart Surgery and During the 24 Hours Thereafter. (Double Blind Prospective Randomised Study)"[NCT04046861] | 200 participants (Anticipated) | Interventional | 2023-02-01 | Not yet recruiting | |||
| Protocolized Care for Early Septic Shock[NCT00510835] | 1,351 participants (Actual) | Interventional | 2008-03-31 | Completed | |||
| Comparative Analysis Between Ringer's Lactate vs Acetate Containing Balanced Crystalloid Solution (Plasma Lyte-A) as Cardiopulmonary Bypass Prime[NCT03043131] | Phase 3 | 60 participants (Anticipated) | Interventional | 2017-02-10 | Not yet recruiting | ||
| Lactate Clearance and Mortality in Patients With Severe Sepsis and Septic Shock: Comparison by Hepatic Dysfunction[NCT01709565] | 245 participants (Anticipated) | Observational | 2012-07-31 | Recruiting | |||
| The Effect of Pre- and Postoperative Supplemental Enteral Nutrition in High-Risk Patients Undergoing Elective Cardiac Surgery. A Prospective Double Blind Study.[NCT00247793] | 0 participants | Interventional | 1996-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary study outcome is hospital mortality (defined as the number of deaths prior to discharge or 60 days, whichever comes first). The secondary outcomes are duration of survival (90 day and 1 year) and clinical evidence of organ dysfunction. (NCT00510835)
Timeframe: prior to discharge or 60 days, whichever comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Early Goal Directed Therapy (EGDT) | 92 |
| Protocolized Standard Care (PSC) | 81 |
| Usual Care | 86 |
26 reviews available for lactic acid and Shock
| Article | Year |
|---|---|
Utilization and Efficacy of Resuscitation Endpoints in Trauma and Burn Patients: A Review Article.
Topics: Acid-Base Equilibrium; Bicarbonates; Blood Pressure; Blood Volume; Burns; Heart Rate; Humans; Lactic | 2022 |
[Lactate in emergency medicine].
Topics: Emergency Medicine; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Shock | 2020 |
Lactate and microcirculation as suitable targets for hemodynamic optimization in resuscitation of circulatory shock.
Topics: Fluid Therapy; Hemodynamics; Humans; Lactic Acid; Microcirculation; Myocardial Infarction; Resuscita | 2017 |
Detailing the cardiovascular profile in shock patients.
Topics: Carbon Dioxide; Critical Illness; Fluid Therapy; Hemodynamics; Humans; Lactic Acid; Microcirculation | 2017 |
Beyond Mean Arterial Pressure and Lactate: Perfusion End Points for Managing the Shocked Patient.
Topics: Acute Kidney Injury; Arterial Pressure; Biomarkers; Blood Circulation; Carbon Dioxide; Cardiac Outpu | 2019 |
Lactate or ScvO2 as an endpoint in resuscitation of shock states?
Topics: Endpoint Determination; Humans; Hypoxia; Lactic Acid; Oxygen; Prognosis; Resuscitation; Shock; Shock | 2013 |
Etiology and therapeutic approach to elevated lactate levels.
Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Heart Arrest; Humans; Lactic Acid; PubM | 2013 |
Etiology and therapeutic approach to elevated lactate levels.
Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Heart Arrest; Humans; Lactic Acid; PubM | 2013 |
Etiology and therapeutic approach to elevated lactate levels.
Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Heart Arrest; Humans; Lactic Acid; PubM | 2013 |
Etiology and therapeutic approach to elevated lactate levels.
Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Heart Arrest; Humans; Lactic Acid; PubM | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Circulatory shock.
Topics: Cardiotonic Agents; Cardiovascular Agents; Diagnosis, Differential; Fluid Therapy; Humans; Lactic Ac | 2013 |
Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup.
Topics: Acidosis, Lactic; Consciousness; Delphi Technique; Humans; Hydrogen-Ion Concentration; Lactic Acid; | 2015 |
Endpoints in resuscitation.
Topics: ADAM Proteins; ADAMTS13 Protein; Biomarkers; Critical Illness; Disintegrins; Endpoint Determination; | 2015 |
Lactate levels and hemodynamic coherence in acute circulatory failure.
Topics: Hemodynamics; Humans; Lactic Acid; Perfusion; Shock | 2016 |
Extending the role of lactate measurement into the prehospital environment.
Topics: Blood Specimen Collection; Emergency Medical Services; Hospital Mortality; Humans; Lactic Acid; Shoc | 2009 |
Early identification of shock in critically ill patients.
Topics: Acid-Base Imbalance; Blood Gas Monitoring, Transcutaneous; Emergency Service, Hospital; Humans; Hypo | 2010 |
Sublingual capnometry: an alternative to gastric tonometry for the management of shock resuscitation.
Topics: Blood Volume; Capnography; Critical Care; Forecasting; Humans; Lactic Acid; Monitoring, Physiologic; | 2003 |
Lactate and shock state: the metabolic view.
Topics: Humans; Hypoxia; Lactic Acid; Shock | 2006 |
Lactate and shock state: the metabolic view.
Topics: Humans; Hypoxia; Lactic Acid; Shock | 2006 |
Lactate and shock state: the metabolic view.
Topics: Humans; Hypoxia; Lactic Acid; Shock | 2006 |
Lactate and shock state: the metabolic view.
Topics: Humans; Hypoxia; Lactic Acid; Shock | 2006 |
Measurement of acid-base resuscitation endpoints: lactate, base deficit, bicarbonate or what?
Topics: Acidosis; Bicarbonates; Catheterization, Swan-Ganz; Cell Hypoxia; Hemoglobins; Humans; Hydrogen-Ion | 2006 |
Glucose metabolism and catecholamines.
Topics: Adrenergic beta-Agonists; Animals; Carbohydrate Metabolism; Catecholamines; Glucose; Glycolysis; Hum | 2007 |
Vasopressin in catecholamine-refractory shock in children.
Topics: Adolescent; Adult; Arginine Vasopressin; Blood Pressure; Catecholamines; Child; Child, Preschool; Do | 2008 |
Prognostic value of blood lactate in critically ill patients.
Topics: Acidosis; Acute Disease; Heart Arrest; Humans; Hypnotics and Sedatives; Intensive Care Units; Lactat | 1984 |
Circulatory shock: a review.
Topics: Adenosine Triphosphate; Blood Coagulation; Blood Pressure; Cardiac Output; Glycolysis; Hemolysis; Hu | 1981 |
Patterns of oxygen transport in trauma and their relationship to outcome.
Topics: Humans; Inflammation; Lactates; Lactic Acid; Oxygen; Prognosis; Shock; Wounds and Injuries | 1994 |
Pathophysiology and treatment of circulatory shock.
Topics: Animals; Critical Care; Cytokines; Dogs; Dopamine; Fluid Therapy; Hemodynamics; Humans; Lactates; La | 1993 |
Assessing perfusion failure during circulatory shock.
Topics: Blood Gas Analysis; Critical Care; Hemodynamics; Humans; Lactates; Lactic Acid; Monitoring, Physiolo | 1993 |
In search of the optimal end points of resuscitation in trauma patients: a review.
Topics: Acidosis; Biomarkers; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Lactic Acid; Oxygen; Resus | 1998 |
[Serum lactate level as a indicator of tissue hypoxia in severely ill patients].
Topics: Acid-Base Imbalance; Acidosis, Lactic; Cell Hypoxia; Fluid Therapy; Humans; Lactic Acid; Severity of | 2000 |
Lactic acidosis in critical illness.
Topics: Acidosis, Lactic; Bicarbonates; Blood Gas Analysis; Carbonates; Citric Acid Cycle; Critical Illness; | 1992 |
6 trials available for lactic acid and Shock
| Article | Year |
|---|---|
Vasopressin in Vasodilatory Shock for Both Left and Right Heart Anomalous Pediatric Patients After Cardiac Surgery.
Topics: Adolescent; Blood Pressure; Cardiopulmonary Bypass; Child; Child, Preschool; Female; Heart Defects, | 2018 |
Association of Clinical Hypoperfusion Variables With Lactate Clearance and Hospital Mortality.
Topics: Adult; Aged; Female; Hospital Mortality; Humans; Hyperlactatemia; Infections; Lactic Acid; Male; Mid | 2018 |
The association between plasma miR-122-5p release pattern at admission and all-cause mortality or shock after out-of-hospital cardiac arrest.
Topics: Aged; Cardiopulmonary Resuscitation; Case-Control Studies; Female; Humans; Lactic Acid; Male; MicroR | 2019 |
Effects of early enteral arginine supplementation on resuscitation of severe burn patients.
Topics: Adolescent; Adult; Arginine; Blood Pressure; Burns; Dietary Supplements; Enteral Nutrition; Female; | 2007 |
Hypertonic sodium lactate versus lactated ringer's solution for intravenous fluid therapy in operations on the abdominal aorta.
Topics: Aorta, Abdominal; Female; Fluid Therapy; Humans; Hypertonic Solutions; Intraoperative Care; Isotonic | 1983 |
Prospective, randomized trial of hypertonic sodium lactate versus lactated Ringer's solution for burn shock resuscitation.
Topics: Adult; Burns; Clinical Trials as Topic; Female; Humans; Isotonic Solutions; Lactates; Lactic Acid; M | 1989 |
109 other studies available for lactic acid and Shock
| Article | Year |
|---|---|
Evaluation of Venous-to-Arterial Carbon Dioxide Tension Difference as a Complementary Parameter During Pediatric Septic Shock Resuscitation: A Prospective Observational Study.
Topics: Blood Gas Analysis; Carbon Dioxide; Child; Humans; Lactic Acid; Shock; Shock, Septic; Veins | 2022 |
Lactate and base deficit combination score for predicting blood transfusion need in blunt multi-trauma patients.
Topics: Adult; Blood Transfusion; Female; Glasgow Coma Scale; Humans; Lactic Acid; Male; Multiple Trauma; Sh | 2022 |
Association Between the Acidemia, Lactic Acidosis, and Shock Severity With Outcomes in Patients With Cardiogenic Shock.
Topics: Acidosis; Acidosis, Lactic; Aged; Cohort Studies; Female; Humans; Lactic Acid; Male; Shock; Shock, C | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Prospective analysis of intoxicated patients developing shock and/or organ failure.
Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac | 2022 |
Veno-arterial CO
Topics: Carbon Dioxide; Heart Arrest; Humans; Lactic Acid; Prognosis; Shock | 2023 |
The role of cardiac power and lactate clearance as an indicator of resuscitation success among pediatric patients with shock in the intensive care unit of Cipto Mangunkusumo Hospital.
Topics: Child; Hospitals; Humans; Intensive Care Units; Lactic Acid; Resuscitation; Shock; Shock, Septic | 2023 |
Venous blood lactate concentrations in patients with shock: Interesting but not really helpful.
Topics: Humans; Lactic Acid; Resuscitation; Sepsis; Shock; Veins | 2020 |
Prognostic value of serial lactate levels in septic patients with and without shock.
Topics: Aged; Aged, 80 and over; Female; Hospitalization; Humans; Lactic Acid; Male; Middle Aged; Organ Dysf | 2019 |
Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model.
Topics: Animals; Arterioles; Brain; Cerebrovascular Circulation; Disease Models, Animal; Hypovolemia; Hypoxi | 2020 |
The Prognostic Value of Lactate in Cardiac Intensive Care Unit Patients With Cardiac Arrest and Shock.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Heart Arrest; Hospital Mortality; Humans; Intensive Car | 2021 |
Continuous lactate monitoring in critically ill patients using microdialysis.
Topics: Critical Care; Critical Illness; Humans; Lactic Acid; Microdialysis; Shock | 2020 |
Evaluation of the rectal-interdigital temperature gradient as a diagnostic marker of shock in dogs.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Temperature; Case-Control Studies; Dog D | 2020 |
Admission base deficit is superior to lactate in identifying shock and resuscitative needs in trauma patients.
Topics: Acid-Base Imbalance; Biomarkers; Blood Transfusion; Female; Humans; Injury Severity Score; Lactic Ac | 2020 |
Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model.
Topics: Aniline Compounds; Animals; Blood Transfusion; Disease Models, Animal; Endothelium, Vascular; Lactic | 2021 |
Arterial or cuff pressure: Clinical predictors among patients in shock in a critical care resuscitation unit.
Topics: Arteries; Blood Pressure; Blood Pressure Determination; Critical Care; Female; Humans; Lactic Acid; | 2021 |
Use of Shock Index and Lactate to Predict Mortality in Acute Heart Failure Patients in Emergency Department.
Topics: Emergency Service, Hospital; Heart Failure; Hospital Mortality; Humans; Lactic Acid; Prognosis; Retr | 2021 |
Clinical evaluation of a novel subcutaneous lactate monitor.
Topics: Critical Care; Female; Humans; Lactic Acid; Male; Monitoring, Physiologic; Sepsis; Shock | 2022 |
Assessment of Tissue Perfusion Using the Peripheral Perfusion Index and Lactate Clearance in Shock in Pediatric Patients.
Topics: Child, Preschool; Female; Humans; Infant; Lactic Acid; Male; Perfusion Index; Predictive Value of Te | 2021 |
Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock.
Topics: Adrenal Cortex Hormones; Angiopoietin-2; Biomarkers; C-Reactive Protein; Cardiotonic Agents; Child; | 2021 |
Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock.
Topics: Adrenal Cortex Hormones; Angiopoietin-2; Biomarkers; C-Reactive Protein; Cardiotonic Agents; Child; | 2021 |
Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock.
Topics: Adrenal Cortex Hormones; Angiopoietin-2; Biomarkers; C-Reactive Protein; Cardiotonic Agents; Child; | 2021 |
Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock.
Topics: Adrenal Cortex Hormones; Angiopoietin-2; Biomarkers; C-Reactive Protein; Cardiotonic Agents; Child; | 2021 |
Cardio-haemodynamic assessment and venous lactate in severe dengue: Relationship with recurrent shock and respiratory distress.
Topics: Adolescent; Child; Echocardiography; Female; Heart; Hemodynamics; Humans; Intensive Care Units; Lact | 2017 |
A comparison of two different fluid resuscitation management protocols for pediatric burn patients: A retrospective study.
Topics: Acid-Base Equilibrium; Burns; Child; Child, Preschool; Female; Fluid Therapy; Humans; Infant; Lactic | 2018 |
[Value of arterial blood lactic acid in the evaluation of disease severity and prognosis in neonatal shock].
Topics: Arteries; Female; Humans; Infant, Newborn; Lactic Acid; Male; Prognosis; Severity of Illness Index; | 2018 |
Base deficit is superior to lactate in trauma.
Topics: Acid-Base Imbalance; Biomarkers; Blood Component Transfusion; Blood Gas Analysis; California; Female | 2018 |
Prehospital Lactate Predicts Need for Resuscitative Care in Non-hypotensive Trauma Patients.
Topics: Adult; Blood Pressure; Emergency Medical Services; Female; Humans; Lactic Acid; Male; Prospective St | 2018 |
Blood lactate concentration and shock index associated with massive transfusion in emergency department patients with primary postpartum haemorrhage.
Topics: Adult; Arterial Pressure; Blood Transfusion; Emergency Medical Services; Emergency Service, Hospital | 2018 |
Aortic branch vessel flow during resuscitative endovascular balloon occlusion of the aorta.
Topics: Animals; Aorta; Arteries; Balloon Occlusion; Blood Flow Velocity; Disease Models, Animal; Endovascul | 2019 |
Lactate and venoarterial carbon dioxide difference/arterial-venous oxygen difference ratio, but not central venous oxygen saturation, predict increase in oxygen consumption in fluid responders.
Topics: Acute Disease; Aged; Blood Gas Analysis; Carbon Dioxide; Fluid Therapy; Hemodynamics; Humans; Intens | 2013 |
Variable assessment of the circulation in intensive care unit patients with shock.
Topics: Arterial Pressure; Cardiac Output; Clinical Competence; Critical Care; Diuresis; Fluid Therapy; Hear | 2013 |
Elevated lactate level and shock index in nontraumatic hypotensive patients presenting to the emergency department.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Emergency Service, Hospital; Female; History, Ancient; H | 2015 |
The characteristics and correlation between the ischemia-reperfusion and changes of redox status in the early stage of severe burns.
Topics: Adult; Burns; Case-Control Studies; Cohort Studies; Disease Progression; Hematocrit; Humans; Hypoxia | 2015 |
Sulfide Intoxication-Induced Circulatory Failure is Mediated by a Depression in Cardiac Contractility.
Topics: Air Pollutants; Anesthesia; Animals; Arterial Pressure; Blood Gas Analysis; Cardiac Output; Heart Ve | 2016 |
Association of blood lactate concentration with physical perfusion variables, blood pressure, and outcome for cats treated at an emergency service.
Topics: Animals; Blood Pressure; Cat Diseases; Cats; Female; Hospitals, Animal; Lactic Acid; Male; Shock; Tr | 2015 |
Lactate-guided resuscitation saves lives: no.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: yes.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Lactate-guided resuscitation saves lives: we are not sure.
Topics: Biomarkers; Humans; Lactic Acid; Resuscitation; Shock | 2016 |
Twenty-four-hour packed red blood cell requirement is the strongest independent prognostic marker of mortality in ED trauma patients.
Topics: Adult; Erythrocyte Transfusion; Female; Humans; Injury Severity Score; Lactic Acid; Male; Prognosis; | 2016 |
Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.
Topics: Animals; Bicarbonates; Burns; Capillary Permeability; Disease Models, Animal; Dogs; Fluid Therapy; F | 2016 |
[Retrospective study on the myocardial damage of 252 patients with severe burn].
Topics: Body Surface Area; Burn Units; Burns; Fluid Therapy; Hematocrit; Hemoglobins; Humans; Lactic Acid; M | 2016 |
Relationship between Central and Peripheral Venous Oxygen Saturation and Lactate Levels: A Prospective Study.
Topics: Aged; Aged, 80 and over; Blood Gas Analysis; Central Venous Catheters; Female; Humans; Lactic Acid; | 2016 |
Continuous Normothermic Ex Vivo Kidney Perfusion Improves Graft Function in Donation After Circulatory Death Pig Kidney Transplantation.
Topics: Animals; Aspartate Aminotransferases; Biomarkers; Cold Ischemia; Creatinine; Delayed Graft Function; | 2017 |
Clinical study of a new Modified Early Warning System scoring system for rapidly evaluating shock in adults.
Topics: Adult; Aged; APACHE; Area Under Curve; Arterial Pressure; Biomedical Research; Early Diagnosis; Emer | 2017 |
Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department.
Topics: Aged; Aged, 80 and over; Comorbidity; Diabetes Mellitus; Emergency Service, Hospital; Female; Hospit | 2017 |
Ultrasonic cardiac output monitoring and microcirculation: is it worthwhile to consider in reconstructive microsurgery?
Topics: Animals; Cardiac Output; Female; Glucose; Graft Occlusion, Vascular; Humans; Lactic Acid; Microcircu | 2009 |
The use of theraputic plasma exchange (TPE) in the setting of refractory burn shock.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Pressure; Burns; Female; Fluid Therapy; Humans; Lactic Ac | 2010 |
Measurement of lactate in a prehospital setting is related to outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Emergency Medical Services; Feasibility Studies; Female; | 2009 |
Early increase in arterial lactate concentration under epinephrine infusion is associated with a better prognosis during shock.
Topics: Adult; Aged; Aged, 80 and over; Epinephrine; Female; Humans; Infusion Pumps; Intensive Care Units; L | 2010 |
Lactate is a better predictor than systolic blood pressure for determining blood requirement and mortality: could prehospital measures improve trauma triage?
Topics: Adult; Blood Pressure; Cohort Studies; Erythrocyte Transfusion; Female; Humans; Lactic Acid; Male; P | 2010 |
Comparison of lactate, base excess, bicarbonate, and pH as predictors of mortality after severe trauma in rhesus macaques (Macaca mulatta).
Topics: Acid-Base Equilibrium; Acidosis; Animals; Bicarbonates; Biomarkers; Female; Housing, Animal; Hydroge | 2010 |
Lactic acid as a factor in the production of irreversibility in oligohaemic shock.
Topics: Animals; Dogs; Lactic Acid; Shock | 1966 |
Imbalance of arginine and asymmetric dimethylarginine is associated with markers of circulatory failure, organ failure and mortality in shock patients.
Topics: Aged; Area Under Curve; Arginine; Biomarkers; Blood Coagulation; Blood Glucose; Carbonates; Creatine | 2012 |
A role for solvents in the toxicity of agricultural organophosphorus pesticides.
Topics: Agriculture; Animals; Cholinesterase Inhibitors; Cyclohexanones; Dimethoate; Emulsions; Humans; Inse | 2012 |
Hyperfibrinolysis in out of hospital cardiac arrest is associated with markers of hypoperfusion.
Topics: Aged; Blood Coagulation Disorders; Female; Fibrinolysis; Humans; Hydrogen-Ion Concentration; Lactic | 2012 |
Implications for burn shock resuscitation of a new in vivo human vascular microdosing technique (microdialysis) for dermal administration of noradrenaline.
Topics: Administration, Cutaneous; Adult; Burns; Dermis; Dose-Response Relationship, Drug; Female; Glucose; | 2012 |
Interrelationship between blood and tissue lactate in a general intensive care unit: a subcutaneous adipose tissue microdialysis study on 162 critically ill patients.
Topics: Adipose Tissue; Aged; Extracellular Fluid; Female; Health Status Indicators; Humans; Intensive Care | 2012 |
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro | 2013 |
Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock.
Topics: Animals; Cytokines; Disease Models, Animal; Isotonic Solutions; Lactic Acid; Lipopolysaccharides; Ma | 2002 |
Enterococcus faecalis exacerbates burn injury-induced host responses in rats.
Topics: Albumins; Animals; Burns; Carbon Dioxide; Enterococcus faecalis; Gram-Positive Bacterial Infections; | 2002 |
Mortality and the nature of metabolic acidosis in children with shock.
Topics: Acid-Base Equilibrium; Acidosis; Blood Gas Analysis; Child; Chlorides; Hospital Mortality; Hospitals | 2003 |
Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients.
Topics: Aged; APACHE; Biomarkers; Blood Gas Analysis; Capnography; Carbon Dioxide; Catheterization, Swan-Gan | 2003 |
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Serum lactate and base deficit as predictors of mortality and morbidity.
Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C | 2003 |
Assessment of adipose tissue metabolism by means of subcutaneous microdialysis in patients with sepsis or circulatory failure.
Topics: Adipose Tissue; Adult; Aged; Blood Glucose; Case-Control Studies; Fatty Acids, Nonesterified; Female | 2003 |
EXCESS LACTATE: AN INDEX OF REVERSIBILITY OF SHOCK IN HUMAN PATIENTS.
Topics: Animals; Blood Chemical Analysis; Dogs; Humans; Hypoxia; Lactates; Lactic Acid; Metabolism; Oxygen; | 1964 |
LACTICACIDOSIS: A CLINICALLY SIGNIFICANT ASPECT OF SHOCK.
Topics: Acidosis; Bicarbonates; Blood Chemical Analysis; Female; Humans; Lactates; Lactic Acid; Myocardial I | 1964 |
THE CLINICAL SIGNIFICANCE OF ELEVATED BLOOD LACTATE.
Topics: Acidosis; Acidosis, Lactic; Blood; Chemical Phenomena; Chemistry; Geriatrics; Humans; Hypertension; | 1965 |
REFRACTORY SEPTIC SHOCK IN MAN. ROLE OF LACTATE AND PYRUVATE METABOLISM AND ACID-BASE BALANCE IN PROGNOSIS.
Topics: Acid-Base Equilibrium; Acidosis; Humans; Lactates; Lactic Acid; Male; Metabolism; Prognosis; Pyruvat | 1965 |
BURN SHOCK AND EXTRAVASCULAR SODIUM DEFICIENCY--TREATMENT WITH RINGER'S SOLUTION WITH LACTATE.
Topics: Burns; Calcium Chloride; Drug Therapy; Humans; Infusions, Parenteral; Isotonic Solutions; Lactates; | 1965 |
Dopexamine reverses colonic but not gastric mucosal perfusion defects in lethal endotoxin shock.
Topics: Animals; Anti-Inflammatory Agents; Carbon Dioxide; Cardiac Output; Colon; Dopamine; Endotoxemia; End | 2003 |
Intraperitoneal injections of India ink and ox bile and the blood lactic acid in rats.
Topics: Animals; Bile; Carbon; Injections, Intraperitoneal; Ink; Lactic Acid; Phosphates; Potassium Compound | 1950 |
Can we distinguish between different types of local perfusion/metabolic derangement by regional venous concentrations of intermediary energy substrates?
Topics: Animals; Endotoxins; Glucose; Glycerol; Lactic Acid; Microdialysis; Perfusion; Pyruvic Acid; Reperfu | 2004 |
Pharmacological study of BRS, a new bicarbonated Ringer's solution, in haemorrhagic shock dogs.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Do | 2005 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; | 2005 |
Neurochemical monitoring using intracerebral microdialysis during systemic haemorrhage.
Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabol | 2007 |
Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock.
Topics: Animals; Female; Glucose; Graft Occlusion, Vascular; Lactic Acid; Microdialysis; Models, Biological; | 2007 |
Lactate, pyruvate, and acid-soluble phosphates in monkey brains treated with carbon dioxide and electric shock.
Topics: Animals; Brain; Brain Chemistry; Carbon Dioxide; Convulsive Therapy; Haplorhini; Humans; Lactates; L | 1949 |
Increased aerobic glycolysis through beta2 stimulation is a common mechanism involved in lactate formation during shock states.
Topics: Animals; Epinephrine; Glycolysis; Hypoxia; Lactic Acid; Male; Oxygen; Rats; Rats, Wistar; Receptors, | 2008 |
Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chl | 2008 |
Cardiac biomarkers, electrolytes, and other analytes in collapsed marathon runners: implications for the evaluation of runners following competition.
Topics: Acidosis, Lactic; Adult; Biomarkers; Blood Chemical Analysis; Calcium; Female; Humans; Hyponatremia; | 2008 |
Comparative studies with Fluosol, Dextran, their mixture, or autologous blood in experimental hypovolemic shock.
Topics: Animals; Blood Pressure; Blood Substitutes; Blood Transfusion, Autologous; Dextrans; Drug Combinatio | 1983 |
[Clinical evaluations of tourniquet shock, with special references to the circulation and biochemistry of the blood].
Topics: Adolescent; Adult; Aged; Carbon Dioxide; Electrolytes; Female; Hemodynamics; Humans; Lactates; Lacti | 1983 |
The relative prognostic value of lactate and haemodynamic measurements in early shock.
Topics: Blood Pressure; Body Temperature; Critical Care; Humans; Lactates; Lactic Acid; Monitoring, Physiolo | 1984 |
Lactate and shock.
Topics: Humans; Lactates; Lactic Acid; Prognosis; Shock | 1984 |
The fall of cardiac output in endotoxemic rats cannot explain all changes in organ blood flow: a comparison between endotoxin and low venous return shock.
Topics: Animals; Blood Gas Analysis; Blood Glucose; Cardiac Output; Catheterization; Hematocrit; Hemodynamic | 1996 |
[Behavior of the lactate level in occlusion and reperfusion of the right superior mesenteric artery. An animal experiment study].
Topics: Animals; Blood Pressure; Hydrogen-Ion Concentration; Intestinal Mucosa; Ischemia; Lactic Acid; Mesen | 1996 |
Resuscitation of the critically ill in the ED: responses of blood pressure, heart rate, shock index, central venous oxygen saturation, and lactate.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Cell Hypoxia; Critical Illness; Emergenc | 1996 |
Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase.
Topics: Acidosis, Lactic; Animals; Cells, Cultured; Cyclooxygenase 2; Endotoxemia; Endotoxins; Enzyme Induct | 1997 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Sublingual capnometry: a new noninvasive measurement for diagnosis and quantitation of severity of circulatory shock.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Blood Gas Monitoring, Transcutaneo | 1999 |
[Serum lactate levels as an indicator of tissue hypoxia in severely ill patients].
Topics: Acidosis, Lactic; Cell Hypoxia; Humans; Lactic Acid; Severity of Illness Index; Shock; Sodium Bicarb | 2000 |
Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions.
Topics: Acidosis, Lactic; APACHE; Biomarkers; Critical Care; Emergencies; Female; Finland; Glasgow Coma Scal | 2000 |
Interleukin-1beta alters the oxygen delivery-oxygen consumption relationship in rabbits by increasing the slope of the supply-independent line.
Topics: Animals; Cardiac Tamponade; Female; Humans; Hypotension; Hypoxia; Interleukin-1; Lactic Acid; Models | 2000 |
[Serum lactate level as an indicator of tissue hypoxia in severely ill patients].
Topics: Acidosis, Lactic; Cell Hypoxia; Humans; Lactic Acid; Severity of Illness Index; Shock | 2000 |
Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients.
Topics: Algorithms; Blood Gas Analysis; Blood Pressure; Cardiac Output; Critical Care; Decision Trees; Diast | 2001 |
CD8(+)-T-cell depletion ameliorates circulatory shock in Plasmodium berghei-infected mice.
Topics: Acidosis, Lactic; Adenosine Triphosphatases; Animals; Anion Transport Proteins; Capillary Permeabili | 2001 |
Sublingual capnometry and indexes of tissue perfusion in patients with circulatory failure.
Topics: APACHE; Blood Circulation; Capnography; Carbon Dioxide; Cardiac Output, Low; Gastric Mucosa; Hemodyn | 2001 |
[Analysis of anionic gap and lactic acid levels significance in metabolic acidosis in small children].
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Anions; Child, Preschool; Diarrhea, Infantile; Female; Huma | 1995 |
Lactate and acid base changes in the critically ill.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Catecholamines; Hemofiltration; Humans; Lactates; | 1991 |
Physiology of blood flow and oxygen utilization by peripheral tissue in circulatory shock.
Topics: Blood Flow Velocity; Heart Arrest; Hemodynamics; Humans; Lactates; Lactic Acid; Oxygen Consumption; | 1990 |
Effects of fructose 1,6-diphosphate on splanchnic artery occlusion shock in the rat.
Topics: Animals; Constriction; Fructosediphosphates; Hexosediphosphates; Lactates; Lactic Acid; Macrophages; | 1989 |
[Cellular metabolic consideration in the pathophysiology and the treatment of shock].
Topics: Humans; Ketone Bodies; Lactates; Lactic Acid; Multiple Organ Failure; Osmolar Concentration; Oxygen; | 1989 |
[Significance of lactate analysis in clinical tests].
Topics: Acidosis, Lactic; Diabetes Mellitus; Heart Diseases; Humans; Lactates; Lactic Acid; Liver Diseases; | 1989 |
Naloxone: ineffective in improving cardiac performance after hypoperfusion in swine.
Topics: Animals; beta-Endorphin; Cardiopulmonary Bypass; Coronary Circulation; Endorphins; Hemodynamics; Lac | 1985 |
Comparison of isotonic and hypertonic fluids in resuscitation from hypovolemic shock.
Topics: Animals; Blood Pressure; Carbon Monoxide; Diuresis; Fluid Therapy; Hypertonic Solutions; Lactates; L | 1986 |
Is blood lactate determination really reliable and useful in critically ill patients with liver disease?
Topics: Humans; Lactates; Lactic Acid; Liver Diseases; Shock | 1988 |
Relation of arterial blood lactate to oxygen delivery and hemodynamic variables in human shock states.
Topics: Arteries; Biological Availability; Hemodynamics; Humans; Lactates; Lactic Acid; Oxygen; Oxygen Consu | 1987 |
The acidosis of cholera. Contributions of hyperproteinemia, lactic acidemia, and hyperphosphatemia to an increased serum anion gap.
Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Adult; Blood Proteins; Cations, Divalent; Cholera; Dehy | 1986 |
Delayed lactate clearance in patients surviving circulatory shock.
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; | 1985 |
Prognosis in shock.
Topics: Humans; Lactates; Lactic Acid; Prognosis; Shock | 1986 |
[Multiple injury and severe multiple injury (remarks on definition and pathophysiology].
Topics: Abdominal Injuries; Adolescent; Adult; Aged; Blood Coagulation Factors; Brain Injuries; Child; Child | 1985 |