lactic acid has been researched along with Shock, Traumatic in 23 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Shock, Traumatic: Shock produced as a result of trauma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities." | 7.76 | Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. ( Gao, W; Koenigsberg, MD; Philbin, NB; Sloan, EP, 2010) |
| "Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities." | 3.76 | Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. ( Gao, W; Koenigsberg, MD; Philbin, NB; Sloan, EP, 2010) |
| "Metabolic acidosis has been proposed as the gold standard to define shock in trauma patients." | 1.42 | Determining the utility of metabolic acidosis for trauma patients in the emergency department. ( Caputo, ND; Fraser, RM; Kanter, M; Simon, R; Summersgill, A, 2015) |
| "Tachycardia is an important early sign of shock in trauma." | 1.37 | Discrepancy between heart rate and makers of hypoperfusion is a predictor of mortality in trauma patients. ( Ishikawa, K; Matsuoka, T; Mizushima, Y; Ueno, M; Watanabe, H, 2011) |
| "Current pre-hospital trauma triage systems are based mainly on physiological parameters, but in compensated shock injury severity may not be immediately obvious, as the physiological parameters remain normal for some time." | 1.31 | Early increases in blood lactate following injury. ( Coats, TJ; Lockey, D; Russell, M; Smith, JE, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 11 (47.83) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, MC | 1 |
| Alarhayem, A | 1 |
| Convertino, V | 1 |
| Carter, R | 1 |
| Chung, K | 1 |
| Stewart, R | 1 |
| Myers, J | 1 |
| Dent, D | 1 |
| Liao, L | 1 |
| Cestero, R | 1 |
| Nicholson, S | 1 |
| Muir, M | 1 |
| Schwaca, M | 1 |
| Wampler, D | 1 |
| DeRosa, M | 1 |
| Eastridge, BJ | 1 |
| Burša, F | 1 |
| Pleva, L | 1 |
| Máca, J | 1 |
| Sklienka, P | 1 |
| Ševčík, P | 1 |
| Lei, Y | 1 |
| Peng, X | 1 |
| Liu, L | 1 |
| Dong, Z | 1 |
| Li, T | 1 |
| Summersgill, A | 1 |
| Kanter, M | 2 |
| Fraser, RM | 1 |
| Caputo, ND | 2 |
| Simon, R | 2 |
| Fraser, R | 1 |
| Sloan, EP | 1 |
| Koenigsberg, MD | 1 |
| Philbin, NB | 1 |
| Gao, W | 1 |
| Gryth, D | 1 |
| Rocksén, D | 1 |
| Drobin, D | 1 |
| Druid, H | 1 |
| Weitzberg, E | 1 |
| Bursell, J | 1 |
| Olsson, LG | 1 |
| Arborelius, UP | 1 |
| Mizushima, Y | 1 |
| Ueno, M | 1 |
| Watanabe, H | 1 |
| Ishikawa, K | 1 |
| Matsuoka, T | 1 |
| Coats, TJ | 1 |
| Smith, JE | 1 |
| Lockey, D | 1 |
| Russell, M | 1 |
| Nirmalan, M | 1 |
| Willard, T | 1 |
| Edwards, DJ | 1 |
| Dark, P | 1 |
| Little, RA | 1 |
| Su, QH | 1 |
| Yu, JJ | 1 |
| Yang, MJ | 1 |
| Zhou, HM | 1 |
| Zhu, JQ | 1 |
| Szalay, L | 1 |
| Umar, F | 1 |
| Khadem, A | 1 |
| Jafarmadar, M | 1 |
| Fürst, W | 2 |
| Ohlinger, W | 1 |
| Redl, H | 2 |
| Bahrami, S | 1 |
| Balogh, Z | 1 |
| McKinley, BA | 1 |
| Cocanour, CS | 1 |
| Kozar, RA | 1 |
| Cox, CS | 1 |
| Moore, FA | 1 |
| Crookes, BA | 1 |
| Cohn, SM | 1 |
| Burton, EA | 1 |
| Nelson, J | 1 |
| Proctor, KG | 1 |
| Gumanenko, EK | 1 |
| Nemchenko, NS | 1 |
| Goncharov, AV | 1 |
| Pashkovskiĭ, EV | 1 |
| Kamolz, LP | 1 |
| Andel, H | 1 |
| Schramm, W | 1 |
| Meissl, G | 1 |
| Herndon, DN | 1 |
| Frey, M | 1 |
| Rixen, D | 1 |
| Siegel, JH | 1 |
| Oda, J | 1 |
| Ueyama, M | 1 |
| Yamashita, K | 1 |
| Inoue, T | 1 |
| Noborio, M | 1 |
| Ode, Y | 1 |
| Aoki, Y | 1 |
| Sugimoto, H | 1 |
| Santangelo, ML | 1 |
| Usberti, M | 1 |
| Di Salvo, E | 1 |
| Belli, G | 1 |
| Romano, G | 1 |
| Sassaroli, C | 1 |
| Zotti, G | 1 |
| Kincaid, EH | 1 |
| Miller, PR | 1 |
| Meredith, JW | 1 |
| Chang, MC | 1 |
| Wang, J | 1 |
| Yang, Z | 1 |
| Zhang, H | 1 |
| Onarheim, H | 1 |
| Reed, RK | 1 |
| Laurent, TC | 1 |
| Lieners, C | 1 |
| Molnar, H | 1 |
| Hallström, S | 1 |
| Schlag, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CRI and Continuous Assessment of Hemodynamic Compensation to Guide Fluid and Pressor Management in Severely Ill Patients With COVID-19[NCT04457817] | 16 participants (Actual) | Observational | 2020-12-01 | Terminated (stopped due to Lack of feasibility) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Shock, Traumatic
| Article | Year |
|---|---|
Bench-to-bedside review: oxygen debt and its metabolic correlates as quantifiers of the severity of hemorrhagic and post-traumatic shock.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Disease Models, Animal; Dogs; Humans; Hypovolemia; Hypoxia | 2005 |
3 trials available for lactic acid and Shock, Traumatic
| Article | Year |
|---|---|
[Clinical investigation of the correlation between blood concentration of lactic acid and tissue oxygenation in severely burned patients].
Topics: Adult; Burns; Female; Fluid Therapy; Humans; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Sho | 2003 |
Hypertonic lactated saline resuscitation reduces the risk of abdominal compartment syndrome in severely burned patients.
Topics: Abdomen; Adolescent; Adult; Aged; Burns; Compartment Syndromes; Drug Combinations; Female; Humans; I | 2006 |
Enalaprilat improves gut perfusion in critically injured patients.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Digestive System; Enalaprilat; Female; Gastric Muco | 1998 |
19 other studies available for lactic acid and Shock, Traumatic
| Article | Year |
|---|---|
Comparison of compensatory reserve and arterial lactate as markers of shock and resuscitation.
Topics: Adult; Biomarkers; Blood Volume; Female; Humans; Lactic Acid; Male; Predictive Value of Tests; Prosp | 2017 |
Tissue ischemia microdialysis assessments following severe traumatic haemorrhagic shock: lactate/pyruvate ratio as a new resuscitation end point?
Topics: Adult; Cardiac Output; Female; Hemoglobins; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; O | 2014 |
Beneficial effect of cyclosporine A on traumatic hemorrhagic shock.
Topics: Animals; Cyclosporine; Cytokines; Female; Hemodynamics; Hydrogen-Ion Concentration; Kidney; Lactic A | 2015 |
Determining the utility of metabolic acidosis for trauma patients in the emergency department.
Topics: Acidosis; Adolescent; Adult; Blood Transfusion; Cohort Studies; Humans; Hydrogen-Ion Concentration; | 2015 |
Comparing biomarkers of traumatic shock: the utility of anion gap, base excess, and serum lactate in the ED.
Topics: Acid-Base Equilibrium; Adult; Biomarkers; Emergency Service, Hospital; Female; Humans; Hydrogen-Ion | 2015 |
Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation.
Topics: Acidosis, Lactic; Adult; Aspirin; Emergency Medical Services; Emergency Treatment; Europe; Fluid The | 2010 |
Effects of fluid resuscitation with hypertonic saline dextrane or Ringer's acetate after nonhemorrhagic shock caused by pulmonary contusion.
Topics: Acute Lung Injury; Animals; Blood Pressure; Contusions; Dextrans; Disease Models, Animal; Extravascu | 2010 |
Discrepancy between heart rate and makers of hypoperfusion is a predictor of mortality in trauma patients.
Topics: Acidosis, Lactic; Adult; Blood Pressure; Heart Rate; Humans; Injury Severity Score; Lactic Acid; Log | 2011 |
Early increases in blood lactate following injury.
Topics: Adult; Aged; Aged, 80 and over; Blood Chemical Analysis; Emergency Medical Services; Humans; Injury | 2002 |
Effects of sustained post-traumatic shock and initial fluid resuscitation on extravascular lung water content and pulmonary vascular pressures in a porcine model of shock.
Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Extravascular Lung Water; Female; F | 2003 |
Increased plasma D-lactate is associated with the severity of hemorrhagic/traumatic shock in rats.
Topics: Animals; Blood Pressure; Body Weight; Endotoxins; Hydrogen-Ion Concentration; Lactic Acid; Male; Pre | 2003 |
Patients with impending abdominal compartment syndrome do not respond to early volume loading.
Topics: Abdomen; Acid-Base Imbalance; Adult; Blood Transfusion; Compartment Syndromes; Crystalloid Solutions | 2003 |
Noninvasive muscle oxygenation to guide fluid resuscitation after traumatic shock.
Topics: Animals; Arteries; Female; Femur; Fluid Therapy; Hindlimb; Hydrogen-Ion Concentration; Lactic Acid; | 2004 |
[Pathogenetical features of the acute period of traumatic disease. Traumatic shock as a special manifestation of the acute period].
Topics: Abdominal Injuries; Acidosis; Acute Disease; Coma, Post-Head Injury; Disseminated Intravascular Coag | 2004 |
Lactate: early predictor of morbidity and mortality in patients with severe burns.
Topics: Biomarkers; Burns; Female; Fluid Therapy; Humans; Injury Severity Score; Lactic Acid; Male; Prognosi | 2005 |
A study of the pathology of the crush syndrome.
Topics: Adolescent; Adult; Creatine; Creatine Kinase; Creatinine; Crush Syndrome; Diagnosis, Differential; D | 1982 |
[The effects of massive escharectomy on the resuscitation of burn shock in the early stage after burn].
Topics: Animals; Blood Viscosity; Burns; Cardiac Output; Dogs; Lactic Acid; Male; Oxygen Consumption; Resusc | 2000 |
Increased plasma concentrations of hyaluronan after major thermal injury in the rat.
Topics: Animals; Burns; Disease Models, Animal; Female; Hyaluronic Acid; Lactates; Lactic Acid; Molecular We | 1992 |
Lipidperoxidation in a canine model of hypovolemic-traumatic shock.
Topics: Aldehydes; Animals; Disease Models, Animal; Dogs; Free Radicals; Hydrogen Peroxide; Hypoxanthine; Hy | 1989 |