lactic acid has been researched along with Scleroderma, Systemic in 4 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dermal fibrosis was histologically observed at day 7 after injection and remained present at day 21." | 5.35 | Mouse model of dermal fibrosis induced by one-time injection of bleomycin-poly(L-lactic acid) microspheres. ( Ishikawa, O; Negishi, I; Shibusawa, Y; Tabata, Y, 2008) |
| "Dermal fibrosis was histologically observed at day 7 after injection and remained present at day 21." | 1.35 | Mouse model of dermal fibrosis induced by one-time injection of bleomycin-poly(L-lactic acid) microspheres. ( Ishikawa, O; Negishi, I; Shibusawa, Y; Tabata, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pucinelli, ML | 3 |
| Fontenelle, S | 1 |
| Andrade, LE | 3 |
| Kayser, C | 2 |
| Fontenelle, SM | 2 |
| Shibusawa, Y | 1 |
| Negishi, I | 1 |
| Tabata, Y | 1 |
| Ishikawa, O | 1 |
1 trial available for lactic acid and Scleroderma, Systemic
| Article | Year |
|---|---|
Cold stimulus fingertip lacticemy test--an effective method to monitor acute therapeutic intervention on primary Raynaud's phenomenon and systemic sclerosis.
Topics: Administration, Sublingual; Adult; Cold Temperature; Cross-Over Studies; Double-Blind Method; Drug M | 2008 |
3 other studies available for lactic acid and Scleroderma, Systemic
| Article | Year |
|---|---|
Determination of fingertip lacticemy before and after cold stimulus in patients with primary Raynaud's phenomenon and systemic sclerosis.
Topics: Adult; Case-Control Studies; Cohort Studies; Cold Temperature; Female; Fingers; Humans; Lactic Acid; | 2002 |
Cold stimulus-fingertip lacticemy: standardization of the test in normal volunteers and diagnostic application for systemic sclerosis.
Topics: Adolescent; Adult; Case-Control Studies; Cold Temperature; Female; Fingers; Humans; Lactic Acid; Mal | 2005 |
Mouse model of dermal fibrosis induced by one-time injection of bleomycin-poly(L-lactic acid) microspheres.
Topics: Animals; Bleomycin; Chemokine CCL2; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Conne | 2008 |