lactic acid has been researched along with Sarcoma 180 in 11 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Sarcoma 180: An experimental sarcoma of mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results demonstrate that methotrexate-loaded implants had significant antitumor efficacy in a sarcoma 180 mouse model without dose-limiting side effects, and suggest that the implants could be potentially applied as an intratumoral delivery system to treat cancer." | 7.85 | Enhanced antitumor efficacy of poly(D,L-lactide-co-glycolide)-based methotrexate-loaded implants on sarcoma 180 tumor-bearing mice. ( Duan, D; Gao, L; Liu, X; Luo, L; Xia, L; Xu, J; Zhang, R, 2017) |
| "These results demonstrate that methotrexate-loaded implants had significant antitumor efficacy in a sarcoma 180 mouse model without dose-limiting side effects, and suggest that the implants could be potentially applied as an intratumoral delivery system to treat cancer." | 3.85 | Enhanced antitumor efficacy of poly(D,L-lactide-co-glycolide)-based methotrexate-loaded implants on sarcoma 180 tumor-bearing mice. ( Duan, D; Gao, L; Liu, X; Luo, L; Xia, L; Xu, J; Zhang, R, 2017) |
| "Usnic acid (UA) is a secondary metabolite produced by lichens, which exhibits an anti-tumour activity." | 1.32 | In vitro and in vivo properties of usnic acid encapsulated into PLGA-microspheres. ( Alves, AJ; Gonçalves, EC; Honda, NK; Nascimento, SC; Ribeiro-Costa, RM; Santos, NP; Santos-Magalhães, NS; Silva, NH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, L | 1 |
| Xia, L | 1 |
| Zhang, R | 1 |
| Duan, D | 1 |
| Liu, X | 1 |
| Xu, J | 1 |
| Luo, L | 1 |
| FODOR, PJ | 1 |
| CLARKE, DA | 1 |
| BODANSKY, O | 1 |
| Miura, H | 1 |
| Onishi, H | 4 |
| Sasatsu, M | 2 |
| Machida, Y | 4 |
| Ribeiro-Costa, RM | 1 |
| Alves, AJ | 1 |
| Santos, NP | 1 |
| Nascimento, SC | 2 |
| Gonçalves, EC | 1 |
| Silva, NH | 1 |
| Honda, NK | 2 |
| Santos-Magalhães, NS | 2 |
| da Silva Santos, NP | 1 |
| Wanderley, MS | 1 |
| Pontes-Filho, NT | 1 |
| da Silva, JF | 1 |
| de Castro, CM | 1 |
| Pereira, EC | 1 |
| da Silva, NH | 1 |
| Kunii, R | 2 |
| Yu, L | 1 |
| Chang, GT | 1 |
| Zhang, H | 1 |
| Ding, JD | 1 |
| Ueki, K | 1 |
| Koyama, K | 1 |
| Murata, N | 1 |
| Takashima, Y | 1 |
| Toyoshima, K | 1 |
| Yamamoto, M | 1 |
| Okada, H | 1 |
| Singh, UV | 1 |
| Udupa, N | 1 |
11 other studies available for lactic acid and Sarcoma 180
| Article | Year |
|---|---|
Enhanced antitumor efficacy of poly(D,L-lactide-co-glycolide)-based methotrexate-loaded implants on sarcoma 180 tumor-bearing mice.
Topics: Animals; Antineoplastic Agents; Calorimetry, Differential Scanning; Delayed-Action Preparations; Dru | 2017 |
Glycolysis by Sarcoma 180 of mice treated with 6-mercaptopurine. I. The role of various enzymes in lactate production.
Topics: Adenosine Triphosphatases; Animals; Fructose-Bisphosphate Aldolase; Glucose; Glycolysis; Isomerases; | 1962 |
Antitumor characteristics of methoxypolyethylene glycol-poly(DL-lactic acid) nanoparticles containing camptothecin.
Topics: Animals; Antineoplastic Agents; Camptothecin; Lactic Acid; Male; Mice; Nanostructures; Polyethylene | 2004 |
In vitro and in vivo properties of usnic acid encapsulated into PLGA-microspheres.
Topics: Animals; Antineoplastic Agents; Benzofurans; Cell Proliferation; Chromatography, High Pressure Liqui | 2004 |
Nanoencapsulation of usnic acid: An attempt to improve antitumour activity and reduce hepatotoxicity.
Topics: Animals; Benzofurans; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Disease Progression; | 2006 |
Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin.
Topics: Algorithms; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Chromatograp | 2007 |
Injectable block copolymer hydrogels for sustained release of a PEGylated drug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Camptothecin; Delayed-Action Pr | 2008 |
Particle characteristics and biodistribution of camptothecin-loaded PLA/(PEG-PPG-PEG) nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Delayed-Action | 2008 |
Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Drug Stability; Female; Gene Silencing; Injections, Intral | 2008 |
Preparation and biodisposition of methoxypolyethylene glycol amine-poly(DL-lactic acid) copolymer nanoparticles loaded with pyrene-ended poly(DL-lactic acid).
Topics: Animals; Chromatography, Gel; Fluorescent Dyes; Indicators and Reagents; Injections, Intravenous; La | 2008 |
In vitro characterization of methotrexate loaded poly(lactic-co-glycolic) acid microspheres and antitumor efficacy in Sarcoma-180 mice bearing tumor.
Topics: Animals; Antimetabolites, Antineoplastic; Capsules; Drug Carriers; Drug Compounding; Drug Screening | 1997 |