Page last updated: 2024-10-17

lactic acid and Retinal Degeneration

lactic acid has been researched along with Retinal Degeneration in 13 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Nelson, TS1
Simpson, C1
Dyka, F1
Dinculescu, A1
Smith, WC1
Vohra, R1
Sanz-Morello, B1
Tams, ALM1
Mouhammad, ZA1
Freude, KK1
Hannibal, J1
Aldana, BI1
Bergersen, LH1
Kolko, M1
Todorova, V1
Stauffacher, MF1
Ravotto, L1
Nötzli, S1
Karademir, D1
Ebner, LJA1
Imsand, C1
Merolla, L1
Hauck, SM1
Samardzija, M1
Saab, AS1
Barros, LF1
Weber, B1
Grimm, C1
Chen, Y1
Zizmare, L1
Trautwein, C1
Paquet-Durand, F1
Sellers, JT1
Chrenek, MA1
Girardot, PE1
Nickerson, JM1
Pardue, MT1
Boatright, JH1
Fernández-Sánchez, L1
Bravo-Osuna, I1
Lax, P1
Arranz-Romera, A1
Maneu, V1
Esteban-Pérez, S1
Pinilla, I1
Puebla-González, MDM1
Herrero-Vanrell, R2
Cuenca, N1
Puntel, A1
Maeda, A1
Golczak, M1
Gao, SQ1
Yu, G1
Palczewski, K1
Lu, ZR1
Yao, J1
Tucker, BA1
Zhang, X1
Checa-Casalengua, P1
Young, MJ1
Rong, X1
Yang, S1
Miao, H1
Guo, T1
Wang, Z1
Shi, W1
Mo, X1
Yuan, W1
Jin, T1
Winkler, BS1
Sauer, MW1
Starnes, CA1
Andrieu-Soler, C1
Aubert-Pouëssel, A1
Doat, M1
Picaud, S1
Halhal, M1
Simonutti, M1
Venier-Julienne, MC1
Benoit, JP1
Behar-Cohen, F1
LYMAN, CN1
PRESCOTT, JM1
Nilsson, SF1
Mäepea, O1
Alm, A1
Narfström, K1

Other Studies

13 other studies available for lactic acid and Retinal Degeneration

ArticleYear
A Modified Arrestin1 Increases Lactate Production in the Retina and Slows Retinal Degeneration.
    Human gene therapy, 2022, Volume: 33, Issue:13-14

    Topics: Animals; Arrestins; Disease Models, Animal; Electroretinography; Glucose; Lactic Acid; Mice; Mice, I

2022
Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants.
    Cells, 2022, 07-02, Volume: 11, Issue:13

    Topics: Adenosine Triphosphate; Animals; Cell Death; Glutamic Acid; Lactic Acid; Mice; Nitric Oxide; Recepto

2022
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation.
    Molecular neurodegeneration, 2023, 03-07, Volume: 18, Issue:1

    Topics: Glucose; Humans; Hypoxia; Lactic Acid; Oxidative Phosphorylation; Retinal Degeneration; Retinal Rod

2023
Measuring the Release of Lactate from Wild-Type and rd1 Mouse Retina.
    Advances in experimental medicine and biology, 2023, Volume: 1415

    Topics: Animals; Humans; Lactic Acid; Mice; Retina; Retinal Degeneration

2023
Initial Assessment of Lactate as Mediator of Exercise-Induced Retinal Protection.
    Advances in experimental medicine and biology, 2019, Volume: 1185

    Topics: Animals; Brain-Derived Neurotrophic Factor; Lactic Acid; Mice; Neuroprotection; Physical Conditionin

2019
Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Animals; Blindness; Delayed-Action Preparations; Disease Models, Animal; Electroretinography; Lactic

2017
Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles.
    Biomaterials, 2015, Volume: 44

    Topics: Animals; Diterpenes; Electroretinography; Humans; Immunohistochemistry; Lactic Acid; Liver; Mice, Kn

2015
Robust cell integration from co-transplantation of biodegradable MMP2-PLGA microspheres with retinal progenitor cells.
    Biomaterials, 2011, Volume: 32, Issue:4

    Topics: Animals; Biocompatible Materials; Drug Carriers; Drug Delivery Systems; Humans; Hyaluronan Receptors

2011
Effects of erythropoietin-dextran microparticle-based PLGA/PLA microspheres on RGCs.
    Investigative ophthalmology & visual science, 2012, Sep-07, Volume: 53, Issue:10

    Topics: Animals; Apoptosis; Biocompatible Materials; Cell Survival; Cells, Cultured; Delayed-Action Preparat

2012
Effects of L-glutamate/D-aspartate and monensin on lactic acid production in retina and cultured retinal Müller cells.
    Journal of neurochemistry, 2004, Volume: 89, Issue:2

    Topics: Animals; Antimycin A; Cells, Cultured; D-Aspartic Acid; Enzyme Inhibitors; Glutamic Acid; Ionophores

2004
Intravitreous injection of PLGA microspheres encapsulating GDNF promotes the survival of photoreceptors in the rd1/rd1 mouse.
    Molecular vision, 2005, Nov-17, Volume: 11

    Topics: Animals; Antigens, Differentiation; Cell Count; Cell Proliferation; Cell Survival; Drug Carriers; El

2005
Separation of the growth factors for Leuconostoc citrovorum and Lactobacillus leichmannii by means of electrolysis.
    The Journal of biological chemistry, 1949, Volume: 178, Issue:1

    Topics: Electrolysis; Growth; Intercellular Signaling Peptides and Proteins; Lactic Acid; Lactobacillus; Lac

1949
Ocular blood flow and retinal metabolism in abyssinian cats with hereditary retinal degeneration.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Glucose; Cardiovascular Agents; Cats; Choroid; Disease Models, A

2001