Page last updated: 2024-10-17

lactic acid and Respiratory Insufficiency

lactic acid has been researched along with Respiratory Insufficiency in 44 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"We evaluated the ability of four biomarkers (C-Reactive protein (CRP), lactate, mid-regional proadrenomedullin (MR-proADM) and procalcitonin (PCT)) to detect each kind of organ failure considered in the SOFA in 213 patients with infection, sepsis or septic shock, by using multivariate regression analysis and calculation of the area under the receiver operating curve (AUROC)."3.96MR- proADM to detect specific types of organ failure in infection. ( Aldecoa, C; Almansa, R; Andaluz-Ojeda, D; Andrés, C; Bermejo-Martin, JF; Calvo, D; Cicuendez, R; Esteban-Velasco, MC; Martín, S; Martin-Fernandez, M; Muñoz-Bellvís, L; Nogales, L; Ríos-Llorente, A; Sanchez-Barrado, E; Vaquero-Roncero, LM, 2020)
"D-lactic acidosis has been reported in patients after a variety of gastrointestinal surgeries, particularly jejunoileal bypass."3.77An extreme and life-threatening case of recurrent D-lactate encephalopathy. ( Htyte, N; Jones, J; Meisels, I; Sandhu, G; White, L, 2011)
" Reduced ATP and phosphocreatine content, intracellular acidosis related to hypercapnia, increased muscle lactate without alterations of the muscle lactate concentration gradient were observed in the skeletal muscle of the hypercapnic-hypoxemic COPD patients studied, in which group no correlation was found between hypoxia and energy or lactate metabolism parameters."3.67Skeletal muscle energetics, acid-base equilibrium and lactate metabolism in patients with severe hypercapnia and hypoxemia. ( Coffrini, E; Del Canale, S; Fiaccadori, E; Guariglia, A; Ronda, N; Vitali, P, 1987)
"Acute respiratory failure is a type of sepsis complicated by severe organ failure."1.91Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study. ( He, Q; Luo, M, 2023)
"Respiratory failure was the most frequently observed complication (106 [67."1.62Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak. ( Wang, Z, 2021)
"Cellular damage and cardiorespiratory failure are the most common causes of mortality and morbidity after poisoning."1.43Successful Treatment of Aluminium Phosphide Poisoning by Extracorporeal Membrane Oxygenation. ( Hajesmaeili, M; Hassanian-Moghaddam, H; Rahimi, M; Sadeghi, R; Taherkhani, M; Zamani, N, 2016)
"Hemolysis is common in all extracorporeal circuits as evident by the elevated plasma free hemoglobin (PFHb) level."1.42Plasma Free Hemoglobin Is an Independent Predictor of Mortality among Patients on Extracorporeal Membrane Oxygenation Support. ( Caldeira, C; Camporesi, EM; Mangar, D; Mirsaeidi, M; Omar, HR; Socias, S; Sprenker, C, 2015)
"Respiratory depression was measured using plethysmography."1.39Effects of monocarboxylate transporter inhibition on the oral toxicokinetics/toxicodynamics of γ-hydroxybutyrate and γ-butyrolactone. ( Morris, ME; Morse, BL, 2013)
"There are numerous ways to treat the respiratory insufficiency, but sometimes surgical intervention is needed."1.38Bioresorbable distraction device for the treatment of airway problems for infants with Robin sequence. ( Breugem, C; Kon, M; Mink van der Molen, AB; Paes, E; van der Molen, AB, 2012)
"There were 50 cases of type I respiratory failure and 60 cases of type II respiratory failure."1.36[Clinical significance of early lactate clearance rate in patients with respiratory failure]. ( Lin, Y; Zhao, YF; Zhu, XL, 2010)
"Opioids are known to induce respiratory depression."1.35Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats. ( Baud, FJ; Chevillard, L; Mégarbane, B; Risède, P, 2009)
"Uncertainty exists as to whether pectus excavatum causes true physiologic impairments to exercise performance as opposed to lack of fitness due to reluctance to exercise."1.32Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum. ( Cooper, CB; Fonkalsrud, EW; Malek, MH, 2003)
"Children with coma and respiratory distress (CM + RD) had greater evidence of renal dysfunction, lower mean pH and higher mean plasma osmolality than those with respiratory distress (RD) or coma (CM) as isolated findings (mean urea 10."1.30Acidosis in severe childhood malaria. ( English, M; Lowe, B; Marsh, K; Mosobo, M; Obiero, J; Sauerwein, R; Waruiru, C, 1997)
"In patients with acute respiratory failure under these circumstances, intravenous ketogenic emulsion therapy is worth consideration."1.30Adult leigh syndrome: treatment with intravenous soybean oil for acute central respiratory failure. ( Ichikawa, K; Kageyama, Y; Kumagai, R; Miyabayashi, S; Yasui, T, 1999)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19906 (13.64)18.7374
1990's9 (20.45)18.2507
2000's10 (22.73)29.6817
2010's13 (29.55)24.3611
2020's6 (13.64)2.80

Authors

AuthorsStudies
Deng, J1
Zhong, Q1
Luo, M1
He, Q1
Powell, EK1
Reynolds, TS1
Webb, JK1
Kundi, R1
Cantu, J1
Keville, M1
O'Connor, JV1
Stein, DM1
Hanson, MP1
Taylor, BS1
Scalea, TM1
Galvagno, SM1
Ren, J1
Kang, Q1
Wang, F1
Yu, W1
Andrés, C1
Andaluz-Ojeda, D1
Cicuendez, R1
Nogales, L1
Martín, S1
Martin-Fernandez, M1
Almansa, R1
Calvo, D1
Esteban-Velasco, MC1
Vaquero-Roncero, LM1
Ríos-Llorente, A1
Sanchez-Barrado, E1
Muñoz-Bellvís, L1
Aldecoa, C1
Bermejo-Martin, JF1
Wang, Z2
Sommerville, EW1
Zhou, XL1
Oláhová, M1
Jenkins, J1
Euro, L1
Konovalova, S1
Hilander, T1
Pyle, A1
He, L1
Habeebu, S1
Saunders, C1
Kelsey, A1
Morris, AAM1
McFarland, R1
Suomalainen, A1
Gorman, GS1
Wang, ED1
Thiffault, I1
Tyynismaa, H1
Taylor, RW1
Djordjevic, I1
Sabashnikov, A1
Deppe, AC1
Kuhn, E1
Eghbalzadeh, K1
Merkle, J1
Maier, J1
Weber, C1
Azizov, F1
Sindhu, D1
Wahlers, T1
Morse, BL2
Morris, ME2
Omar, HR1
Mirsaeidi, M1
Socias, S1
Sprenker, C1
Caldeira, C1
Camporesi, EM1
Mangar, D1
Roberts, JK1
Disselkamp, M1
Yataco, AC1
di Grezia, F1
di Panzillo, EA1
Russo, S1
Gargiulo, G1
Della-Morte, D1
Testa, G1
Cacciatore, F1
Bonaduce, D1
Abete, P1
Hassanian-Moghaddam, H1
Zamani, N1
Rahimi, M1
Hajesmaeili, M1
Taherkhani, M1
Sadeghi, R1
Avad, AS1
Lutsenko, RV1
Malyk, SV1
Haginoya, K1
Miyabayashi, S2
Kikuchi, M1
Kojima, A1
Yamamoto, K1
Omura, K1
Uematsu, M1
Hino-Fukuyo, N1
Tanaka, S1
Tsuchiya, S1
Chevillard, L1
Mégarbane, B1
Risède, P1
Baud, FJ1
Zhao, YF1
Lin, Y1
Zhu, XL1
Htyte, N1
White, L1
Sandhu, G1
Jones, J1
Meisels, I1
Breugem, C1
Paes, E1
Kon, M1
Mink van der Molen, AB1
van der Molen, AB1
Eddleston, M1
Street, JM1
Self, I1
Thompson, A1
King, T1
Williams, N1
Naredo, G1
Dissanayake, K1
Yu, LM1
Worek, F1
John, H1
Smith, S1
Thiermann, H1
Harris, JB1
Eddie Clutton, R1
Sewall, GK1
Warner, T1
Connor, NP1
Hartig, GK1
Edwards, S1
Malek, MH1
Fonkalsrud, EW1
Cooper, CB1
BRUN, J2
REVOL, A2
BIOT, N2
PERRIN-FAYOLLE, M1
GARDERE, J1
PENMAN, RW1
Lin, VW1
Hsiao, I1
Deng, X1
Lee, YS1
Sasse, S1
Gumanenko, EK1
Nemchenko, NS1
Goncharov, AV1
Pashkovskiĭ, EV1
Bohn, D1
Hrabac, B1
Schönhofer, B1
Geibel, M1
Wenzel, M1
Rosenblüh, J1
Köhler, D1
Pandit, JJ1
Robbins, PA1
English, M1
Sauerwein, R1
Waruiru, C1
Mosobo, M1
Obiero, J1
Lowe, B1
Marsh, K1
De Backer, D1
Creteur, J1
Zhang, H1
Norrenberg, M1
Vincent, JL1
Zauner, A1
Doppenberg, E1
Soukup, J1
Menzel, M1
Young, HF1
Bullock, R1
Rabbat, A1
Laaban, JP1
Boussairi, A1
Rochemaure, J1
Kumagai, R1
Ichikawa, K1
Yasui, T1
Kageyama, Y1
Arbour, R1
Esparis, B1
Ciufo, R1
Dimarco, A1
Stofan, D1
Nethery, D1
Supinski, G1
Jakobsson, EJ1
Jorfeldt, L2
Jakobsson, P1
Brundin, A1
Fiaccadori, E1
Del Canale, S1
Vitali, P1
Coffrini, E1
Ronda, N1
Guariglia, A1
Sadchikov, DV1
Kutyreva, NV1
Lugovskaia, TB1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Feasibility Study to Consider the Relationship Between Markers of Red Cell Damage, Inflammation and the Recovery Process of Newborns Requiring Extracorporeal Membrane Oxygenation (ECMO) for Persistent Pulmonary Hypertension of the Newborn (PPHN): Mi-ECM[NCT02940327]24 participants (Actual)Observational2016-02-19Completed
Aerobic Exercise to Improve Outcomes of Treatment for Methamphetamine Dependence[NCT01103531]135 participants (Actual)Interventional2010-03-31Completed
Phase II Magnetic Alteration of Pectus Excavatum[NCT00466206]Phase 1/Phase 210 participants (Actual)Interventional2007-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Allogenic Red Cell Transfusion Volume

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 24 hours after ECMO is discontinued

Interventionml (Mean)
7+ Days289.6
<7 Days479.2

CD14/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 12 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days1.5
<7 Days0.84

CD14/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 24 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days3.02
<7 Days0.38

CD14/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 24 hours after ECMO decannulation

Interventionpercentage change (Mean)
7+ Days1.01
<7 Days0.40

CD14/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 48 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days0.29
<7 Days0.27

CD14/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 72 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days0.72
<7 Days0.59

CD16/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 12 hours after ECMO commencement

Interventionpercent change (Mean)
7+ Days1.90
<7 Days1.13

CD16/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 24 hours after decannulation

Interventionpercentage change (Mean)
7+ Days1.56
<7 Days0.6

CD16/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 24 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days3.11
<7 Days0.64

CD16/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 48 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days0.73
<7 Days0.4

CD16/41

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 72 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days1.55
<7 Days0.93

CD64/163

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 12 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days8.7
<7 Days4.65

CD64/163

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 24 hours after decannulation

Interventionpercentage change (Mean)
7+ Days3.2
<7 Days2.27

CD64/163

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 24 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days7.34
<7 Days1.89

CD64/163

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 48 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days3.26
<7 Days0.92

CD64/163

Change of markers of platelet and leukocyte activation in arterial blood and analysed by flow cytometry. (NCT02940327)
Timeframe: 72 hours after ECMO commencement

Interventionpercentage change (Mean)
7+ Days3.31
<7 Days1.9

Change of Serum Haemoglobin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 12 hours after ECMO commencement

Interventiong/L (Mean)
7+ Days109.64
<7 Days112.07

Change of Serum Haemoglobin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 24 hours after decannulation

Interventiong/L (Mean)
7+ Days109.25
<7 Days110.23

Change of Serum Haemoglobin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 24 hours after ECMO commencement

Interventiong/L (Mean)
7+ Days114.30
<7 Days109.43

Change of Serum Haemoglobin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 48 hours after ECMO commencement

Interventiong/L (Mean)
7+ Days112.56
<7 Days113.08

Change of Serum Haemoglobin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 72 hours after ECMO commencement

Interventiong/L (Mean)
7+ Days112.90
<7 Days109.89

Change of Serum Haemoglobin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: baseline

Interventiong/L (Mean)
7+ Days151.5
<7 Days145.4

Duration on ECMO

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: > 7 days or did not survive to discharge

Interventionhours (Median)
7+ Days292
<7 Days80

Heart Injury as Determined by Serum Troponin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 12 hours after ECMO commencement

Interventionng/ml (Mean)
7+ Days7.89
<7 Days6.96

Heart Injury as Determined by Serum Troponin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 24 hours after decannulation

Interventionng/ml (Mean)
7+ Days9.54
<7 Days7.44

Heart Injury as Determined by Serum Troponin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 24 hours after ECMO commencement

Interventionng/ml (Mean)
7+ Days3.71
<7 Days3.11

Heart Injury as Determined by Serum Troponin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 48 hours after ECMO commencement

Interventionng/ml (Mean)
7+ Days2.13
<7 Days1.81

Heart Injury as Determined by Serum Troponin Levels

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 72 hours after ECMO commencement

Interventionng/ml (Mean)
7+ Days5.51
<7 Days5.88

Number of Participants Requiring Non Red Cell Transfusion

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: 24 hours after ECMO is discontinued

InterventionParticipants (Count of Participants)
7+ Days10
<7 Days10

Number of Participants With Acute Kidney Injury

Clinical and biochemical markers of organ failure (NCT02940327)
Timeframe: >7 days or did not survive to discharge

Interventionparticipants (Number)
7+ Days3
<7 Days0

Affect on Cardiac Activity

EKG performed prior to implantation, one month post-implantation, and after explanation to evaluate whether magnetic field near the heart adversely affects cardiac activity. Outcome measure describes number of patients who experienced adverse change in EKG. (NCT00466206)
Timeframe: One month post-explantation

Interventionparticipants (Number)
Magnetic Mini-Mover Group0

Damage/Discoloration to Skin

Outcome measure is number of patients who experienced permanent skin damage or discoloration due to external brace wear (NCT00466206)
Timeframe: One-month post-explant

Interventionparticipants (Number)
3MP Treatment Group0

Efficacy: Patient Recommendation of Treatment

"Based on patient response to one-year post-explantation QoL statement: I would recommend this treatment for pectus excavatum (sunken chest) to someone else with pectus excavatum. Ratings: 5-strongly agree; 4-agree; 3-unsure; 2-disagree; 1-strongly disagree" (NCT00466206)
Timeframe: One year post-explanation

InterventionScores on a scale (Mean)
Magnetic Mini-Mover Group4.2

Efficacy: Patient Satisfaction

Based on patient response to one-year post-explantation QoL questionnaire: How satisfied are you with the correction of your chest? Ratings: 5-very satisfied; 4-satisfied; 3-unsure; 2-dissatisfied; 1-very dissatisfied (NCT00466206)
Timeframe: One year post-explant

InterventionScores on a scale (Mean)
3MP Treatment Arm3.7

Patient Compliance

Compliance measured by average number of hours per day external device was worn by patient, as measured by the data sensor and logging device built into external prosthetic (NCT00466206)
Timeframe: 18 months active Rx

Interventionavg hours per day brace worn (Mean)
Treatment Arm16

Reviews

1 review available for lactic acid and Respiratory Insufficiency

ArticleYear
Cellular pathophysiology. Part 2: Responses following hypoxia.
    Professional nurse (London, England), 2003, Volume: 18, Issue:11

    Topics: Blood Volume; Calcium; Cell Membrane; Cell Physiological Phenomena; Energy Metabolism; Free Radicals

2003

Trials

1 trial available for lactic acid and Respiratory Insufficiency

ArticleYear
[FACTORIAL ANALYSIS IN PROGNOSTICATION OF INFECTIOUS COMPLICATIONS AFTER SIMULTANT OPERATIVE INTERVENTIONS FOR BILIARY CALCULOUS DISEASE].
    Klinichna khirurhiia, 2016, Issue:3

    Topics: Aged; Algorithms; Bacterial Infections; Blood Glucose; Cardiomegaly; Cholecystectomy, Laparoscopic;

2016

Other Studies

42 other studies available for lactic acid and Respiratory Insufficiency

ArticleYear
Analysis of prognostic factors for in-hospital mortality in patients with unplanned re-exploration after cardiovascular surgery.
    Journal of cardiothoracic surgery, 2022, Apr-23, Volume: 17, Issue:1

    Topics: Acute Kidney Injury; Creatinine; Female; Hospital Mortality; Humans; Lactic Acid; Male; Prognosis; R

2022
Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study.
    BMC pulmonary medicine, 2023, Jan-30, Volume: 23, Issue:1

    Topics: Humans; Intensive Care Units; Lactic Acid; Nomograms; Prognosis; Respiratory Distress Syndrome; Resp

2023
Early veno-venous extracorporeal membrane oxygenation is an effective strategy for traumatically injured patients presenting with refractory respiratory failure.
    The journal of trauma and acute care surgery, 2023, 08-01, Volume: 95, Issue:2S Suppl 1

    Topics: Extracorporeal Membrane Oxygenation; Hemodynamics; Humans; Lactic Acid; Respiratory Insufficiency; R

2023
Association of lactate/albumin ratio with in-hospital mortality in ICU patients with acute respiratory failure: A retrospective analysis based on MIMIC-IV database.
    Medicine, 2023, Sep-29, Volume: 102, Issue:39

    Topics: Adult; Albumins; Critical Illness; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Re

2023
MR- proADM to detect specific types of organ failure in infection.
    European journal of clinical investigation, 2020, Volume: 50, Issue:6

    Topics: Adrenomedullin; Aged; Aged, 80 and over; Area Under Curve; Blood Coagulation Disorders; C-Reactive P

2020
Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak.
    BMC infectious diseases, 2021, Jan-25, Volume: 21, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antivira

2021
Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy.
    Human molecular genetics, 2019, 01-15, Volume: 28, Issue:2

    Topics: Alanine-tRNA Ligase; Cardiomyopathies; Diseases in Twins; Enzyme Stability; Fibroblasts; Genes, Rece

2019
Risk factors associated with 30-day mortality for out-of-center ECMO support: experience from the newly launched ECMO retrieval service.
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2019, Volume: 22, Issue:2

    Topics: Adult; Aged; Cardiopulmonary Resuscitation; Extracorporeal Membrane Oxygenation; Female; Germany; He

2019
Toxicokinetics/Toxicodynamics of γ-hydroxybutyrate-ethanol intoxication: evaluation of potential treatment strategies.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 346, Issue:3

    Topics: Animals; Central Nervous System Depressants; Conscious Sedation; Drug Overdose; Ethanol; GABA-B Rece

2013
Plasma Free Hemoglobin Is an Independent Predictor of Mortality among Patients on Extracorporeal Membrane Oxygenation Support.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Aged; Biomarkers; Blood Transfusion; Cardiomyopathies; Extracorporeal Membrane Oxygenation; Female;

2015
Oxygen Delivery in Septic Shock.
    Annals of the American Thoracic Society, 2015, Volume: 12, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Erythrocyte Transfusion; Fluid Therapy; Foot Ulcer; Gangrene; Hemodynam

2015
Prognostic role of lactate on mortality in younger and older patients with cardio-respiratory failure admitted to an acute intensive care unit.
    Aging clinical and experimental research, 2016, Volume: 28, Issue:3

    Topics: Acidosis, Lactic; Acute Coronary Syndrome; Aged; Female; Hospital Mortality; Hospitalization; Humans

2016
Successful Treatment of Aluminium Phosphide Poisoning by Extracorporeal Membrane Oxygenation.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:3

    Topics: Adult; Aluminum Compounds; Echocardiography; Extracorporeal Membrane Oxygenation; Heart Failure; Hum

2016
Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: a long-term follow-up study.
    Journal of the neurological sciences, 2009, Mar-15, Volume: 278, Issue:1-2

    Topics: Adolescent; Brain Stem; Evoked Potentials, Auditory, Brain Stem; Follow-Up Studies; Humans; Lactic A

2009
Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Animals; Blood Gas Analysis; Buprenorphine; Catheterization; Fentanyl; Lactic Acid; Male; Methadone;

2009
[Clinical significance of early lactate clearance rate in patients with respiratory failure].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Lactic Acid; Male; Metabolic Clearance Rate; Middle

2010
An extreme and life-threatening case of recurrent D-lactate encephalopathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:4

    Topics: Acidosis, Lactic; Brain Diseases; Humans; Kidney Failure, Chronic; Lactic Acid; Male; Middle Aged; R

2011
Bioresorbable distraction device for the treatment of airway problems for infants with Robin sequence.
    Clinical oral investigations, 2012, Volume: 16, Issue:4

    Topics: Absorbable Implants; Airway Extubation; Airway Obstruction; Biocompatible Materials; Equipment Desig

2012
A role for solvents in the toxicity of agricultural organophosphorus pesticides.
    Toxicology, 2012, Apr-11, Volume: 294, Issue:2-3

    Topics: Agriculture; Animals; Cholinesterase Inhibitors; Cyclohexanones; Dimethoate; Emulsions; Humans; Inse

2012
Effects of monocarboxylate transporter inhibition on the oral toxicokinetics/toxicodynamics of γ-hydroxybutyrate and γ-butyrolactone.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 345, Issue:1

    Topics: 4-Butyrolactone; Absorption; Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug O

2013
Comparison of resorbable poly-L-lactic acid-polyglycolic acid and internal Palmaz stents for the surgical correction of severe tracheomalacia.
    The Annals of otology, rhinology, and laryngology, 2003, Volume: 112, Issue:6

    Topics: Animals; Endoscopy; Granulation Tissue; Lactic Acid; Models, Animal; Polyesters; Polyglycolic Acid;

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
[Blood lactic acid in chronic respiratory insufficiency].
    Le Poumon et le coeur, 1962, Volume: 18

    Topics: Humans; Lactates; Lactic Acid; Pulmonary Valve Insufficiency; Respiratory Insufficiency

1962
[THE BLOOD LACTIC ACID DURING RESPIRATORY INSUFFICIENCY].
    Marseille medical, 1963, Volume: 100

    Topics: Blood Chemical Analysis; Bronchiectasis; Bronchitis; Humans; Lactates; Lactic Acid; Pneumoconiosis;

1963
Blood lactate levels and some blood acidbase changes in respiratory failure and their significance in oxygen induced-respiratory depression.
    Clinical science, 1962, Volume: 23

    Topics: Blood; Blood Chemical Analysis; Humans; Lactates; Lactic Acid; Oxygen; Respiratory Insufficiency; Re

1962
Functional magnetic ventilation in dogs.
    Archives of physical medicine and rehabilitation, 2004, Volume: 85, Issue:9

    Topics: Analysis of Variance; Animals; Blood Gas Analysis; Carbon Dioxide; Cervical Vertebrae; Disease Model

2004
[Pathogenetical features of the acute period of traumatic disease. Traumatic shock as a special manifestation of the acute period].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:6

    Topics: Abdominal Injuries; Acidosis; Acute Disease; Coma, Post-Head Injury; Disseminated Intravascular Coag

2004
Metabolic acidosis in severe asthma: Is it the disease or is it the doctor?
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007, Volume: 8, Issue:6

    Topics: Acidosis; Acute Disease; Albuterol; Asthma; Blood Gas Analysis; Bronchodilator Agents; Child, Presch

2007
[The effect of corticosteroid therapy and global respiratory insufficiency on lactate and amino acid levels in the blood].
    Medicinski arhiv, 1984, Volume: 38, Issue:3

    Topics: Amino Acids; Asthma; Humans; Lactates; Lactic Acid; Methylprednisolone; Respiratory Insufficiency

1984
[Increase in hypercapnia in exercise--an unloading strategy?].
    Medizinische Klinik (Munich, Germany : 1983), 1995, Volume: 90, Issue:1 Suppl 1

    Topics: Adult; Carbon Dioxide; Exercise Test; Female; Home Care Services; Humans; Hypercapnia; Intermittent

1995
The effect of exercise on the development of respiratory depression during sustained isocapnic hypoxia in humans.
    Respiration; international review of thoracic diseases, 1997, Volume: 64, Issue:1

    Topics: Adult; Carbon Dioxide; Chemoreceptor Cells; Exercise; Humans; Hypoxia; Lactic Acid; Male; Oxygen; Re

1997
Acidosis in severe childhood malaria.
    QJM : monthly journal of the Association of Physicians, 1997, Volume: 90, Issue:4

    Topics: Acidosis; Age Factors; Child, Preschool; Coma; Female; Hemoglobins; Humans; Infant; Lactic Acid; Mal

1997
Lactate production by the lungs in acute lung injury.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:4 Pt 1

    Topics: Acute Disease; Animals; Cardiac Output; Female; Humans; Infant, Newborn; Lactic Acid; Lung; Lung Inj

1997
Extended neuromonitoring: new therapeutic opportunities?
    Neurological research, 1998, Volume: 20 Suppl 1

    Topics: Adolescent; Adult; Body Temperature; Brain; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circula

1998
Hyperlactatemia during acute severe asthma.
    Intensive care medicine, 1998, Volume: 24, Issue:4

    Topics: Acidosis, Lactic; Acute Disease; Adult; Arteries; Asthma; Blood Gas Analysis; Disease Progression; F

1998
Adult leigh syndrome: treatment with intravenous soybean oil for acute central respiratory failure.
    European journal of neurology, 1999, Volume: 6, Issue:5

    Topics: Acute Disease; Adult; Diet; Fat Emulsions, Intravenous; Female; Humans; Injections, Intravenous; Ket

1999
Osmolar gap metabolic acidosis in a 60-year-old man treated for hypoxemic respiratory failure.
    Chest, 2000, Volume: 118, Issue:2

    Topics: Acidosis, Lactic; Drug Combinations; Humans; Hypnotics and Sedatives; Hypoxia; Infusions, Intravenou

2000
Dichloroacetate reduces diaphragmatic lactate formation but impairs respiratory performance.
    American journal of respiratory and critical care medicine, 2001, Nov-01, Volume: 164, Issue:9

    Topics: Airway Resistance; Analysis of Variance; Animals; Dichloroacetic Acid; In Vitro Techniques; Lactic A

2001
Blood fuel metabolites at rest and during exercise in patients with advanced chronic obstructive pulmonary disease with and without chronic respiratory failure.
    Respiration; international review of thoracic diseases, 1990, Volume: 57, Issue:5

    Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Carbon Dioxide; Energy Metabolism; Fatty Acids, Nones

1990
Skeletal muscle metabolites and fibre types in patients with advanced chronic obstructive pulmonary disease (COPD), with and without chronic respiratory failure.
    The European respiratory journal, 1990, Volume: 3, Issue:2

    Topics: Adenosine Triphosphate; Biopsy; Creatine; Female; Glycogen; Humans; Lactates; Lactic Acid; Lung Dise

1990
Skeletal muscle energetics, acid-base equilibrium and lactate metabolism in patients with severe hypercapnia and hypoxemia.
    Chest, 1987, Volume: 92, Issue:5

    Topics: Acid-Base Equilibrium; Acute Disease; Adenosine Triphosphate; Aged; Energy Metabolism; Female; Human

1987
[Gas exchange and metabolic functions of the lungs in endotoxic shock].
    Vestnik khirurgii imeni I. I. Grekova, 1985, Volume: 135, Issue:10

    Topics: Acidosis, Respiratory; Animals; Dogs; Female; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic

1985