Page last updated: 2024-10-17

lactic acid and Respiratory Distress Syndrome

lactic acid has been researched along with Respiratory Distress Syndrome in 67 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Dobutamine was used to increase cardiac output, thereby directly varying TO2 under conditions of constant O2 demand."5.29Effects of dobutamine on oxygen transport and consumption in the adult respiratory distress syndrome. ( Dantzker, DR; Gutierrez, G; Krachman, SL; Lodato, RF; Morice, R, 1994)
" Independent covariates related to significant decreases of linezolid concentrations included higher weight, creatinine clearance rates, and fibrinogen and antithrombin concentrations, lower concentrations of lactate, and the presence of acute respiratory distress syndrome (ARDS)."5.22Predictors of Inadequate Linezolid Concentrations after Standard Dosing in Critically Ill Patients. ( Frechen, S; Frey, L; Fuhr, U; Holdt, LM; Maier, B; Scharf, C; Taubert, M; Vogeser, M; Zander, J; Zoller, M, 2016)
" Lactic acidosis and poor cardiac performance, as evidenced by low cardiac index (CI) with normal filling pressures, were seen in all cases of MSOF and RC, as well as in all deaths."3.70The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma. ( Blow, O; Butler, K; Claridge, JA; Magliore, L; Young, JS, 1999)
"Group IV mice had the least acute lung injury, with no detectable interleukin-6 response."2.70Improved resuscitation minimizes respiratory dysfunction and blunts interleukin-6 and nuclear factor-kappa B activation after traumatic hemorrhage. ( Claridge, JA; Schulman, AM; Young, JS, 2002)
"This is also true for patients in septic shock after plasma volume expansion."2.39[Is infection and septic shock caused by a global oxygen deficiency? An overview in 2 parts. 1: Infection and correlation between DO2 and VO2]. ( Ensinger, H; Georgieff, M, 1996)
"Its presence in patients with adult respiratory distress syndrome and/or sepsis has been associated with particularly high mortality rates that may be the result of tissue hypoxia that causes multiple organ failure."2.38Experimental models of pathologic oxygen supply dependency. ( Cain, SM; Curtis, SE, 1991)
"Acute respiratory failure is a type of sepsis complicated by severe organ failure."1.91Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study. ( He, Q; Luo, M, 2023)
"The incidence of acute respiratory distress syndrome (ARDS), cTn I and brain natriuretic peptic in the improved group were significantly lower than those in the control group."1.91Practice and effect evaluation of early restrictive fluid resuscitation strategy in the nursing care of patients with sepsis in the emergency department: a retrospective cohort study. ( Dai, X; Hu, X; Wang, P; Zhang, J, 2023)
"Respiratory failure was the most frequently observed complication (106 [67."1.62Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak. ( Wang, Z, 2021)
"To discuss the risk factors of acute respiratory distress syndrome (ARDS) in patients with sepsis in emergency department."1.42[Analysis of the risk factors of acute respiratory distress syndrome of Berlin new definition in patients with sepsis in emergency department]. ( Liu, Z; Qiao, L, 2015)
"Patients with severe sepsis and septic shock are at high risk for development of pulmonary complications, including acute respiratory distress syndrome (ARDS)."1.42Sepsis-associated pulmonary complications in emergency department patients monitored with serial lactate: An observational cohort study. ( Dettmer, MR; Fuller, BM; Mohr, NM, 2015)
"Complete clinical data of patients with septic shock admitted to emergency intensive care unit (EICU) of Sichuan Provincial People's Hospital from May 1994 to December 2014 were recorded and analyzed."1.42[Improvement effect of early goal-directed therapy on the prognosis in patients with septic shock]. ( Li, C; Yun, D, 2015)
"Sepsis is a serious worldwide health care condition that is associated with high mortality rates, despite improvements in the ability to manage infection."1.39Implications of the new international sepsis guidelines for nursing care. ( Aitken, L; Kleinpell, R; Schorr, CA, 2013)
"Acute respiratory distress syndrome was defined using the Berlin definition."1.39The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. ( Bellamy, SL; Christie, JD; Fuchs, BD; Gaieski, DF; Goyal, M; Lyon, S; Meyer, NJ; Mikkelsen, ME; Miltiades, AN; Shah, CV, 2013)
"Two hundred consecutive acute respiratory distress syndrome patients (age = 57 ± 17, Simplified Acute Physiology Score II = 57 ± 20, overall day-28 mortality = 54%)."1.39Extravascular lung water is an independent prognostic factor in patients with acute respiratory distress syndrome. ( Anguel, N; Jozwiak, M; Monnet, X; Osman, D; Persichini, R; Richard, C; Silva, S; Teboul, JL, 2013)
"Echocardiography demonstrated that right ventricular dysfunction occurred in the absence of recruitment."1.32Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. ( Ackerley, C; Duggan, M; Engelberts, D; Kavanagh, BP; McCaul, CL; McNamara, PJ, 2003)
"Eighty patients with multiple trauma were studied (514 samples) during their intensive care unit courses (Injury Severity Score 27."1.31Metabolic correlates of oxygen debt predict posttrauma early acute respiratory distress syndrome and the related cytokine response. ( Rixen, D; Siegel, JH, 2000)
"Dobutamine was used to increase cardiac output, thereby directly varying TO2 under conditions of constant O2 demand."1.29Effects of dobutamine on oxygen transport and consumption in the adult respiratory distress syndrome. ( Dantzker, DR; Gutierrez, G; Krachman, SL; Lodato, RF; Morice, R, 1994)
"Many patients with adult respiratory distress syndrome exhibit supply dependence of VO2 even at high levels of QO2, which suggests that a peripheral O2 extraction defect may be present."1.27Pathological supply dependence of O2 uptake during bacteremia in dogs. ( Beyer, C; Nelson, DP; Samsel, RW; Schumacker, PT; Wood, LD, 1987)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19905 (7.46)18.7374
1990's18 (26.87)18.2507
2000's11 (16.42)29.6817
2010's19 (28.36)24.3611
2020's14 (20.90)2.80

Authors

AuthorsStudies
Trejnowska, E1
Drobiński, D1
Knapik, P1
Wajda-Pokrontka, M1
Szułdrzyński, K1
Staromłyński, J1
Nowak, W1
Urlik, M1
Ochman, M1
Goździk, W1
Serednicki, W1
Śmiechowicz, J1
Brączkowski, J1
Bąkowski, W1
Kwinta, A1
Zembala, MO1
Suwalski, P1
Zhang, H2
Li, Z2
Zheng, W1
Zhang, L1
Yang, T1
Xie, K1
Yu, Y1
Luo, M1
He, Q1
Pagano, A1
Porta, G1
Bosso, G1
Allegorico, E1
Serra, C1
Mercurio, V1
Sansone, G1
Orefice, S1
Numis, FG1
Hu, X1
Zhang, J1
Wang, P1
Dai, X1
Namayanja, C1
Eregu, EEI1
Ongodia, P1
Okalebo, CB1
Okiror, W1
Okello, F1
Okibure, A1
Paasi, G1
Kakungulu, H1
Grace, A1
Muhindo, R1
Banks, D1
Martin, C1
Taylor-Robinson, S1
Olupot-Olupot, P1
Sánchez Díaz, JS1
Peniche Moguel, KG1
Reyes-Ruiz, JM1
Pérez Nieto, OR1
Escarramán Martínez, D1
Zamarrón López, EI1
Calyeca Sánchez, MV1
Ren, J1
Kang, Q1
Wang, F1
Yu, W2
Blanco-Schweizer, P1
Sánchez-Ballesteros, J1
Bendito, B1
Martín, AI1
Fernández, L1
Piqueras, JM1
Enríquez, P1
Blanco, J1
Pourfathi, M2
Xin, Y2
Rosalino, M1
Cereda, M2
Kadlecek, S2
Duncan, I2
Profka, H2
Hamedani, H2
Siddiqui, S2
Ruppert, K2
Chatterjee, S2
Rizi, RR2
Chen, D1
Liu, X1
Li, J3
Wang, Z2
Guyther, J1
Cantwell, L1
Lu, Y1
Guo, H1
Chen, X1
Zhang, Q1
Lazzeri, C1
Bonizzoli, M1
Cianchi, G1
Batacchi, S1
Terenzi, P1
Cozzolino, M1
Bernardo, P1
Peris, A1
Michard, B1
Artzner, T1
Lebas, B1
Besch, C1
Guillot, M1
Faitot, F1
Lefebvre, F1
Bachellier, P1
Castelain, V1
Maestraggi, Q1
Schneider, F1
Ehrich, J1
Hajjar, LA1
Almeida, JP1
Fukushima, JT1
Rhodes, A1
Vincent, JL3
Osawa, EA1
Galas, FR1
Kleinpell, R1
Aitken, L1
Schorr, CA1
Mikkelsen, ME1
Shah, CV1
Meyer, NJ1
Gaieski, DF1
Lyon, S1
Miltiades, AN1
Goyal, M1
Fuchs, BD1
Bellamy, SL1
Christie, JD1
Zang, Z1
Xu, H1
Dong, L1
Gao, F1
Yan, J1
Li, Y1
Liu, XY1
Ma, MM1
Qi, ZJ1
Zhang, XQ1
Cao, GH1
Zhu, WW1
Wang, XZ1
Voelker, MT1
Busch, T1
Bercker, S1
Fichtner, F1
Kaisers, UX1
Laudi, S1
Ni, L1
Chen, Q1
Zhu, K1
Shi, J1
Shen, J1
Gong, J1
Gao, T1
Li, N1
Lavrentieva, A1
Qiao, L1
Liu, Z1
Dettmer, MR1
Mohr, NM1
Fuller, BM1
Qi, SY1
Wang, WT1
Chu, ZD1
Chen, CY1
Zhou, MK1
Ren, YX1
Liu, XJ1
Li, C1
Yun, D1
Taubert, M1
Zoller, M1
Maier, B1
Frechen, S1
Scharf, C1
Holdt, LM1
Frey, L1
Vogeser, M1
Fuhr, U1
Zander, J1
Zanella, A1
Patroniti, N1
Isgrò, S1
Albertini, M1
Costanzi, M1
Pirrone, F1
Scaravilli, V1
Vergnano, B1
Pesenti, A1
Wu, WH1
Niu, YY1
Zhang, CR1
Xiao, LB1
Ye, HS1
Pan, DM1
Zeng, M1
Jozwiak, M1
Silva, S1
Persichini, R1
Anguel, N1
Osman, D1
Richard, C1
Teboul, JL1
Monnet, X1
Zouaoui, K1
Dulaurent, S1
Gaulier, JM1
Moesch, C1
Lachâtre, G1
Claridge, JA2
Schulman, AM1
Young, JS2
Iscra, F1
Gullo, A1
Biolo, G1
Duggan, M1
McCaul, CL1
McNamara, PJ1
Engelberts, D1
Ackerley, C1
Kavanagh, BP1
Bendjelid, K1
Treggiari, MM1
Romand, JA1
Bruhn, A1
Hernandez, G1
Bugedo, G1
Castillo, L1
Mazza, BF1
Machado, FR1
Mazza, DD1
Hassmann, V1
Claesson, J1
Lehtipalo, S1
Bergstrand, U1
Arnerlöv, C1
Winsö, O1
O'Rourke, J1
Sheeran, P1
Heaney, M1
Talbot, R1
Geraghty, M1
Costello, J1
McDonnell, C1
Newell, J1
Mannion, D1
Riede, U1
Sandritter, W1
Mittermayer, C1
Krachman, SL1
Lodato, RF1
Morice, R1
Gutierrez, G2
Dantzker, DR1
Nimmo, GR1
Mackenzie, SJ1
Walker, S1
Nicol, M1
Grant, IS1
Groeneveld, AB1
Vermeij, CG1
Nauta, JJ1
Thijs, LG2
Ensinger, H1
Georgieff, M1
Brown, SD1
Clark, C1
Douzinas, EE1
Tsidemiadou, PD1
Pitaridis, MT1
Andrianakis, I1
Bobota-Chloraki, A1
Katsouyanni, K1
Sfyras, D1
Malagari, K1
Roussos, C2
De Backer, D2
Creteur, J1
Norrenberg, M1
Gil, A1
Carrizosa, F1
Herrero, A1
Martin, J1
González, J1
Jareño, A1
Rivero, J1
Blow, O1
Magliore, L1
Butler, K1
Routsi, C1
Bardouniotou, H1
Delivoria-Ioannidou, V1
Kazi, D1
Zakynthinos, S1
Mizock, BA1
Kiefer, P1
Nunes, S1
Kosonen, P1
Takala, J1
Rixen, D1
Siegel, JH1
Cain, SM2
Curtis, SE2
Hack, CE1
Hart, M1
van Schijndel, RJ1
Eerenberg, AJ1
Nuijens, JH1
Aarden, LA1
Weg, JG1
Ronco, JJ1
Phang, PT1
Walley, KR1
Wiggs, B1
Fenwick, JC1
Russell, JA1
Kruse, JA1
Haupt, MT1
Puri, VK1
Carlson, RW1
Roman, A1
Kahn, RJ1
Kuo, CD1
Wu, WG1
Wang, JH1
Chen, SM1
Chiang, BN1
Nelson, DP1
Beyer, C1
Samsel, RW1
Wood, LD1
Schumacker, PT1
Rashkin, MC1
Bosken, C1
Baughman, RP1
Sadchikov, DV1
Kutyreva, NV1
Lugovskaia, TB1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Transfusion Requirements After Cardiac Surgery: a Randomized Controlled Clinical Trial (TRACS STUDY)[NCT01021631]Phase 3500 participants (Anticipated)Interventional2009-02-28Recruiting
Drug Monitoring of Antibiotics in Critical Care Patients[NCT01793012]186 participants (Actual)Observational2013-03-31Completed
Hemodynamic Characteristics of Patients With SARS-CoV-2: PiCCOVID Study[NCT04337983]60 participants (Actual)Observational2020-03-13Completed
Early Lactate-Directed Therapy on the ICU: A Randomized Controlled Trial[NCT00270673]Phase 3350 participants (Anticipated)Interventional2006-02-28Completed
Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)[NCT01128413]22 participants (Actual)Interventional2010-07-31Terminated (stopped due to lack of resources)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Lactate Clearance

The median lactate clearance from time zero to within 6 hours of the ED stay. (NCT01128413)
Timeframe: The median lactate clearance within 6 hours of the ED stay.

Interventionpercent lactate clearance (Median)
Fluid Optimization (FO)54
Routine Care (RC)56

Reviews

8 reviews available for lactic acid and Respiratory Distress Syndrome

ArticleYear
Big Tests in Little People.
    Emergency medicine clinics of North America, 2021, Volume: 39, Issue:3

    Topics: Asthma; Biomarkers; Child; Fibrin Fibrinogen Degradation Products; Heart Diseases; Humans; Infection

2021
Critical care of burn patients. New approaches to old problems.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:1

    Topics: Burns; Critical Care; Extracorporeal Membrane Oxygenation; Fluid Therapy; Hemodynamics; Humans; Hype

2016
Bench-to-bedside review: lactate and the lung.
    Critical care (London, England), 2002, Volume: 6, Issue:4

    Topics: Glucose; Humans; Lactic Acid; Lung; Respiratory Distress Syndrome; Sepsis

2002
Circulatory shock: a review.
    Pathology, 1981, Volume: 13, Issue:2

    Topics: Adenosine Triphosphate; Blood Coagulation; Blood Pressure; Cardiac Output; Glycolysis; Hemolysis; Hu

1981
[Is infection and septic shock caused by a global oxygen deficiency? An overview in 2 parts. 1: Infection and correlation between DO2 and VO2].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1996, Volume: 31, Issue:3

    Topics: Acid-Base Equilibrium; Cardiac Output; Humans; Hypoxia; Lactates; Lactic Acid; Oxygen; Oxygen Consum

1996
Lung injury and lactate production: a hypoxic stimulus?
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Biomarkers; Humans; Hypoxia; Lactic Acid; Lung; Respiratory Distress Syndrome

1999
Experimental models of pathologic oxygen supply dependency.
    Critical care medicine, 1991, Volume: 19, Issue:5

    Topics: Animals; Endotoxins; Humans; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Respiratory Distress

1991
Oxygen transport in adult respiratory distress syndrome and other acute circulatory problems: relationship of oxygen delivery and oxygen consumption.
    Critical care medicine, 1991, Volume: 19, Issue:5

    Topics: Biological Transport; Cardiac Output; Humans; Infections; Lactates; Lactic Acid; Multiple Organ Fail

1991

Trials

4 trials available for lactic acid and Respiratory Distress Syndrome

ArticleYear
High lactate levels are predictors of major complications after cardiac surgery.
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:2

    Topics: Acute Kidney Injury; Age Factors; Aged; Biomarkers; Brazil; Cardiac Surgical Procedures; Chi-Square

2013
Predictors of Inadequate Linezolid Concentrations after Standard Dosing in Critically Ill Patients.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Aged; Anti-Bacterial Agents; Body Weight; Creatinine; Critical Illness; Drug Administration Schedule

2016
Improved resuscitation minimizes respiratory dysfunction and blunts interleukin-6 and nuclear factor-kappa B activation after traumatic hemorrhage.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Airway Resistance; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Cardiopulmonary Resuscitat

2002
Pulmonary lactate release in patients with acute lung injury is not attributable to lung tissue hypoxia.
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Biomarkers; Cell Hypoxia; Hemodynamics; Humans; Lactic Acid; Lung; Middle Aged; Prospective Studies;

1999

Other Studies

55 other studies available for lactic acid and Respiratory Distress Syndrome

ArticleYear
Extracorporeal membrane oxygenation for severe COVID-19-associated acute respiratory distress syndrome in Poland: a multicenter cohort study.
    Critical care (London, England), 2022, 04-07, Volume: 26, Issue:1

    Topics: Adult; Cohort Studies; COVID-19; Extracorporeal Membrane Oxygenation; Hospital Mortality; Humans; La

2022
Risk stratification of patients with acute respiratory distress syndrome complicated with sepsis using lactate trajectories.
    BMC pulmonary medicine, 2022, Sep-07, Volume: 22, Issue:1

    Topics: APACHE; Humans; Lactic Acid; Respiratory Distress Syndrome; Risk Assessment; Sepsis

2022
Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study.
    BMC pulmonary medicine, 2023, Jan-30, Volume: 23, Issue:1

    Topics: Humans; Intensive Care Units; Lactic Acid; Nomograms; Prognosis; Respiratory Distress Syndrome; Resp

2023
Blood lactate in mild and moderate ARDS secondary to SARS COV 2.
    The American journal of emergency medicine, 2023, Volume: 66

    Topics: COVID-19; Humans; Lactic Acid; Respiratory Distress Syndrome; RNA, Viral; SARS-CoV-2

2023
Practice and effect evaluation of early restrictive fluid resuscitation strategy in the nursing care of patients with sepsis in the emergency department: a retrospective cohort study.
    JBI evidence implementation, 2023, Sep-01, Volume: 21, Issue:3

    Topics: Emergency Service, Hospital; Humans; Lactic Acid; Nursing Care; Respiratory Distress Syndrome; Retro

2023
Unusual clinical spectra of childhood severe malaria during malaria epidemic in eastern Uganda: a prospective study.
    Malaria journal, 2023, Jun-01, Volume: 22, Issue:1

    Topics: Adolescent; Anemia; Blackwater Fever; Child; Child, Preschool; Epidemics; Female; Humans; Infant; Ja

2023
The ∆Pv-aCO2/∆Ca-vO2 ratio as a predictor of mortality in patients with severe acute respiratory distress syndrome related to COVID-19.
    PloS one, 2023, Volume: 18, Issue:9

    Topics: Carbon Dioxide; COVID-19; Humans; Lactic Acid; Respiratory Distress Syndrome; Retrospective Studies;

2023
Association of lactate/albumin ratio with in-hospital mortality in ICU patients with acute respiratory failure: A retrospective analysis based on MIMIC-IV database.
    Medicine, 2023, Sep-29, Volume: 102, Issue:39

    Topics: Adult; Albumins; Critical Illness; Hospital Mortality; Humans; Intensive Care Units; Lactic Acid; Re

2023
Resuscitation with albumin using BET formula keeps at bay fluid administration in burned patients. An observational study.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Albumins; Body Surface Area; Burns; Colloids; Disease Progression;

2020
Pulmonary pyruvate metabolism as an index of inflammation and injury in a rat model of acute respiratory distress syndrome.
    NMR in biomedicine, 2020, Volume: 33, Issue:11

    Topics: Animals; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Adhesion M

2020
Lactate levels and clearance rate in neonates undergoing mechanical ventilation in Tibet.
    The Journal of international medical research, 2020, Volume: 48, Issue:10

    Topics: Humans; Infant, Newborn; Lactic Acid; Prognosis; Respiration, Artificial; Respiratory Distress Syndr

2020
Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak.
    BMC infectious diseases, 2021, Jan-25, Volume: 21, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antivira

2021
Association between lactate/albumin ratio and all-cause mortality in patients with acute respiratory failure: A retrospective analysis.
    PloS one, 2021, Volume: 16, Issue:8

    Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Critical Care; Female; Humans; Intensive Care Un

2021
Lactate and Echocardiography Before Veno-Venous Extracorporeal Membrane Oxygenation Support.
    Heart, lung & circulation, 2018, Volume: 27, Issue:1

    Topics: Biomarkers; Echocardiography; Extracorporeal Membrane Oxygenation; Female; Humans; Hyperlactatemia;

2018
Liver transplantation in critically ill patients: Preoperative predictive factors of post-transplant mortality to avoid futility.
    Clinical transplantation, 2017, Volume: 31, Issue:12

    Topics: Adult; Critical Illness; Female; Follow-Up Studies; Graft Rejection; Humans; Lactic Acid; Liver Fail

2017
Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.
    Scientific reports, 2018, 02-23, Volume: 8, Issue:1

    Topics: Acute Lung Injury; Animals; Biomarkers; Carbon Isotopes; Disease Models, Animal; Gene Expression; Hu

2018
Implications of the new international sepsis guidelines for nursing care.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2013, Volume: 22, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Blood; Central Venous Pressure; Evidence-Based Nursing; Fluid Therapy;

2013
The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis.
    Shock (Augusta, Ga.), 2013, Volume: 40, Issue:5

    Topics: Aged; APACHE; Biomarkers; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Incidence

2013
[Prognostic significance of early lactate clearance rate for severe acute respiratory failure patients on extracorporeal membrane oxygenation].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2014, Volume: 37, Issue:3

    Topics: Extracorporeal Membrane Oxygenation; Humans; Kaplan-Meier Estimate; Lactic Acid; Metabolic Clearance

2014
Changes in intestinal microflora in rats with acute respiratory distress syndrome.
    World journal of gastroenterology, 2014, May-21, Volume: 20, Issue:19

    Topics: Acute Lung Injury; Amine Oxidase (Copper-Containing); Animals; Biodiversity; Disease Models, Animal;

2014
Restrictive transfusion practice during extracorporeal membrane oxygenation therapy for severe acute respiratory distress syndrome.
    Artificial organs, 2015, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Critical Illness; Erythrocyte Transfusion; Extracorporeal Membrane Ox

2015
The influence of extracorporeal membrane oxygenation therapy on intestinal mucosal barrier in a porcine model for post-traumatic acute respiratory distress syndrome.
    Journal of cardiothoracic surgery, 2015, Feb-15, Volume: 10

    Topics: Animals; Disease Models, Animal; Extracorporeal Membrane Oxygenation; Fatty Acid-Binding Proteins; F

2015
[Analysis of the risk factors of acute respiratory distress syndrome of Berlin new definition in patients with sepsis in emergency department].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:7

    Topics: Berlin; Emergency Service, Hospital; Humans; Incidence; Lactic Acid; Lung Injury; Prognosis; Respira

2015
Sepsis-associated pulmonary complications in emergency department patients monitored with serial lactate: An observational cohort study.
    Journal of critical care, 2015, Volume: 30, Issue:6

    Topics: Adult; Aged; Cohort Studies; Emergency Medicine; Emergency Service, Hospital; Female; Humans; Incide

2015
[The clinical analysis of extracorporeal membrane oxygenation for adult severe acute respiratory distress syndrome].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2016, Apr-12, Volume: 39, Issue:4

    Topics: Adult; Extracorporeal Membrane Oxygenation; Female; Heart Rate; Humans; Intensive Care Units; Lactic

2016
[Improvement effect of early goal-directed therapy on the prognosis in patients with septic shock].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:11

    Topics: Acute Kidney Injury; Arterial Pressure; Blood Gas Analysis; Central Venous Pressure; Fluid Therapy;

2015
Blood acidification enhances carbon dioxide removal of membrane lung: an experimental study.
    Intensive care medicine, 2009, Volume: 35, Issue:8

    Topics: Animals; Carbon Dioxide; Extracorporeal Membrane Oxygenation; Female; Lactic Acid; Lung; Membranes;

2009
Combined APACH II score and arterial blood lactate clearance rate to predict the prognosis of ARDS patients.
    Asian Pacific journal of tropical medicine, 2012, Volume: 5, Issue:8

    Topics: Adult; APACHE; Biomarkers; Female; Humans; Lactic Acid; Linear Models; Male; Middle Aged; Oxygen; Pr

2012
Extravascular lung water is an independent prognostic factor in patients with acute respiratory distress syndrome.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Capillary Permeability; Extravascular Lung Water; Female; Humans; Intensive Care Units; Lactic Acid;

2013
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro

2013
Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs.
    American journal of respiratory and critical care medicine, 2003, Jun-15, Volume: 167, Issue:12

    Topics: Animals; Blood Gas Analysis; Capillary Leak Syndrome; Disease Models, Animal; Echocardiography; Func

2003
Transpulmonary lactate gradient after hypothermic cardiopulmonary bypass.
    Intensive care medicine, 2004, Volume: 30, Issue:5

    Topics: Aged; Aged, 80 and over; Coronary Artery Bypass; Extracorporeal Circulation; Female; Humans; Hypothe

2004
Effects of positive end-expiratory pressure on gastric mucosal perfusion in acute respiratory distress syndrome.
    Critical care (London, England), 2004, Volume: 8, Issue:5

    Topics: Aged; Aged, 80 and over; Carbon Dioxide; Cardiac Output; Female; Gastric Mucosa; Humans; Intensive C

2004
Evaluation of blood transfusion effects on mixed venous oxygen saturation and lactate levels in patients with SIRS/sepsis.
    Clinics (Sao Paulo, Brazil), 2005, Volume: 60, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; APACHE; Blood Transfusion; Female; Hemoglobins

2005
Negative mesenteric effects of lung recruitment maneuvers in oleic acid lung injury are transient and short lasting.
    Critical care medicine, 2007, Volume: 35, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Cardiac O

2007
Effects of sequential changes from conventional ventilation to high-frequency oscillatory ventilation at increasing mean airway pressures in an ovine model of combined lung and head injury.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:5

    Topics: Analysis of Variance; Animals; Blood Flow Velocity; Carbon Dioxide; Cerebral Infarction; Cerebrovasc

2007
Effects of dobutamine on oxygen transport and consumption in the adult respiratory distress syndrome.
    Intensive care medicine, 1994, Volume: 20, Issue:2

    Topics: Adult; Aged; Blood Gas Analysis; Dobutamine; Dose-Response Relationship, Drug; Female; Hemodynamics;

1994
Acid-base responses to high-volume haemofiltration in the critically ill.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:9

    Topics: Acid-Base Imbalance; Acute Kidney Injury; Aged; Aged, 80 and over; Critical Illness; Female; Hemofil

1993
Vasodilating prostaglandin E1 decreases critical oxygen delivery by increasing critical oxygen extraction in anesthetized pigs.
    Circulatory shock, 1993, Volume: 39, Issue:4

    Topics: Alprostadil; Anesthesia; Animals; Cardiac Output; Hemodynamics; Infections; Lactates; Lactic Acid; M

1993
Pulmonary lactate release in patients with sepsis and the adult respiratory distress syndrome.
    Journal of critical care, 1996, Volume: 11, Issue:1

    Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Output; Female; Gastric Mucosa

1996
The regional production of cytokines and lactate in sepsis-related multiple organ failure.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:1

    Topics: Aged; Craniocerebral Trauma; Cytokines; Female; Humans; Interleukin-1; Interleukin-6; Lactic Acid; L

1997
Lactate production by the lungs in acute lung injury.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:4 Pt 1

    Topics: Acute Disease; Animals; Cardiac Output; Female; Humans; Infant, Newborn; Lactic Acid; Lung; Lung Inj

1997
Influence of mechanical ventilation on blood lactate in patients with acute respiratory failure.
    Intensive care medicine, 1998, Volume: 24, Issue:9

    Topics: Adult; Aged; Blood Gas Analysis; Female; Follow-Up Studies; Humans; Lactic Acid; Male; Middle Aged;

1998
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
Effect of positive end-expiratory pressure on splanchnic perfusion in acute lung injury.
    Intensive care medicine, 2000, Volume: 26, Issue:4

    Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Indocyanine Green

2000
Metabolic correlates of oxygen debt predict posttrauma early acute respiratory distress syndrome and the related cytokine response.
    The Journal of trauma, 2000, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Cytokines; Enzyme-Linked Immunosorbent

2000
Whole body and regional O2 uptake/delivery and lactate flux in endotoxic dogs.
    Advances in experimental medicine and biology, 1992, Volume: 316

    Topics: Animals; Biological Transport, Active; Dogs; Endotoxins; Kinetics; Lactates; Lactic Acid; Oxygen Con

1992
Interleukin-8 in sepsis: relation to shock and inflammatory mediators.
    Infection and immunity, 1992, Volume: 60, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin; Bacteremia; Blood Pressure; Complem

1992
Oxygen consumption is independent of changes in oxygen delivery in severe adult respiratory distress syndrome.
    The American review of respiratory disease, 1991, Volume: 143, Issue:6

    Topics: Aged; Biological Availability; Blood Transfusion; Hemoglobins; Humans; Lactates; Lactic Acid; Middle

1991
Lactate levels as predictors of the relationship between oxygen delivery and consumption in ARDS.
    Chest, 1990, Volume: 98, Issue:4

    Topics: Humans; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Positive-Pressure Respiration; Pulmonary

1990
Oxygen uptake/supply dependency. Effects of short-term dobutamine infusion.
    The American review of respiratory disease, 1990, Volume: 142, Issue:1

    Topics: Acidosis, Lactic; Aged; Bacterial Infections; Dobutamine; Female; Heart Failure; Humans; Lactates; L

1990
Proton nuclear magnetic resonance studies of plasma to determine metabolic status of patients with adult respiratory distress syndrome.
    Clinical chemistry, 1989, Volume: 35, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetoacetates; Arteries; Blood Proteins; Chromatography, High Press

1989
Pathological supply dependence of O2 uptake during bacteremia in dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:4

    Topics: Animals; Blood Pressure; Dogs; Hemodynamics; Lactates; Lactic Acid; Oxygen Consumption; Pseudomonas

1987
Oxygen delivery in critically ill patients. Relationship to blood lactate and survival.
    Chest, 1985, Volume: 87, Issue:5

    Topics: Adult; Cardiac Output; Humans; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Partial Pressure;

1985
[Gas exchange and metabolic functions of the lungs in endotoxic shock].
    Vestnik khirurgii imeni I. I. Grekova, 1985, Volume: 135, Issue:10

    Topics: Acidosis, Respiratory; Animals; Dogs; Female; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic

1985