Page last updated: 2024-10-17

lactic acid and Reperfusion Injury

lactic acid has been researched along with Reperfusion Injury in 203 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Small-dose infusions of both propofol and NAC appear to provide similar protection against ischaemia-reperfusion injury in arthroscopic knee surgery."9.14Comparison of the effect of propofol and N-acetyl cysteine in preventing ischaemia-reperfusion injury. ( Cekic, B; Coskun, I; Eroglu, A; Erturk, E; Geze, S; Karahan, C; Kerimoglu, S; Kosucu, M; Mentese, A; Ulusoy, H, 2009)
"The effects of amrinone, a selective phosphodiesterase III inhibitor, on liver ischaemia reperfusion injury have not yet been clarified."9.09Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. ( Chang, K; Hanaoka, K; Hayashida, M; Makuuchi, M; Orii, R; Sugawara, Y; Takayama, T; Yamada, Y, 2000)
"To investigate the protective effects of ginkgo diterpene lactone meglumine injection (GDLMI) on cerebral focal ischemia reperfusion injury induced by middle cerebral artery occlusion (MCAO) in rats, and explore its possible mechanism."7.85[Protective effects of Ginkgo Terpene Lactones Meglumine Injection on focal cerebral ischemia in rats]. ( Cao, L; Cao, ZY; Hu, HF; Luo, YP; Wang, ZZ; Xiao, W; Zhang, H; Zhang, XZ, 2017)
"To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline."7.80Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats. ( Belon, AR; Carvalho, JG; Felice Neto, R; Marques, GM; Montero, EF; Rasslan, R; Rasslan, S; Utiyama, EM, 2014)
"The general anesthetic propofol protects the adult heart against ischemia and reperfusion injury; however, its efficacy has not been investigated in the immature heart."7.80Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes. ( Imura, H; Nitta, T; Shirakawa, M, 2014)
"It is well known that puerarin attenuates ischemia-reperfusion injury and promotes function recovery of ischemic region."7.79HP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats. ( Du, D; Jiang, CL; Li, MH; Liu, MF; Meng, Q; Peng, HS; Sun, SL; Tao, HQ; Wang, YM; Yang, HC; Yang, LZ; Ye, W; Yu, H; Zhu, DL, 2013)
"To investigate the effects of preventive enteral administration of ornithine alpha-ketoglutarate (OKG) in an ischemia-reperfusion rat model."7.77Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. ( Garcia, JH; Gonçalves, ES; Guimarães, SB; Prado Neto, AX; Rabelo, CM; Vasconcelos, PR, 2011)
"To study the protective effects of lycopene (LP) on cerebral ischemia-reperfusion injury induced by focal cerebral ischemia and oxidative stress in rats."7.76[The effects of lycopene on reactive oxygen species and anoxic damage in ischemia reperfusion injury in rats]. ( Mai, JY; Shen, H; Shen, XN; Wang, RZ; Wei, Y; Wu, M, 2010)
" Trimetazidine (TMZ) has been reported to exert a protective action against normothermic ischemia and reperfusion injury in several experimental and clinical studies."7.70Efficiency of trimetazidine in renal dysfunction secondary to cold ischemia-reperfusion injury: a proposed addition to University of Wisconsin solution. ( Carretier, M; Eugene, M; Goujon, JM; Hauet, T; Tallineau, C; Tillement, JP, 1998)
"Methylene blue (MB) has been used as a vasopressor in sepsis and acute liver failure."6.70The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation. ( Baumann, J; Bellamy, MC; Gedney, JA; Koelzow, H; Snook, NJ, 2002)
"Global cerebral ischemia was established using the Pulsinelli four-vessel occlusion model and brain temperature was maintained at defined level for 60 min after 20-min ischemia."5.40Changes of c-fos, malondialdehyde and lactate in brain tissue after global cerebral ischemia under different brain temperatures. ( Li, L; Mei, YW; Murong, SX; Sun, SG; Tong, ET; Xu, GY; Zhang, H; Zhang, JJ, 2014)
" In order to reduce rat proteins to elicit possible immune responses in humans, we determined the effect of human AM combined with human AMBP-1 after intestinal ischemia and reperfusion (I/R)."5.35Human adrenomedullin combined with human adrenomedullin binding protein-1 is protective in gut ischemia and reperfusion injury in the rat. ( Blau, SA; Wang, P; Wu, R; Zhang, F; Zhou, M, 2009)
"The focal cerebral ischemia was produced by the occlusion of the right common carotid artery and the right middle cerebral artery for 60 mins."5.31Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. ( Cheng, FC; Chung, SY; Lin, JY; Lin, MC, 2002)
"In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models."5.31Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001)
"Phosphoenolpyruvate (PEP) is a high-energy metabolite in the final step of glycolysis."5.30Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats. ( Chijiiwa, K; Hamasaki, N; Saiki, S; Shimizu, S; Tanaka, M; Yamaguchi, K, 1997)
"Small-dose infusions of both propofol and NAC appear to provide similar protection against ischaemia-reperfusion injury in arthroscopic knee surgery."5.14Comparison of the effect of propofol and N-acetyl cysteine in preventing ischaemia-reperfusion injury. ( Cekic, B; Coskun, I; Eroglu, A; Erturk, E; Geze, S; Karahan, C; Kerimoglu, S; Kosucu, M; Mentese, A; Ulusoy, H, 2009)
"The effects of amrinone, a selective phosphodiesterase III inhibitor, on liver ischaemia reperfusion injury have not yet been clarified."5.09Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. ( Chang, K; Hanaoka, K; Hayashida, M; Makuuchi, M; Orii, R; Sugawara, Y; Takayama, T; Yamada, Y, 2000)
"To investigate the protective effects of ginkgo diterpene lactone meglumine injection (GDLMI) on cerebral focal ischemia reperfusion injury induced by middle cerebral artery occlusion (MCAO) in rats, and explore its possible mechanism."3.85[Protective effects of Ginkgo Terpene Lactones Meglumine Injection on focal cerebral ischemia in rats]. ( Cao, L; Cao, ZY; Hu, HF; Luo, YP; Wang, ZZ; Xiao, W; Zhang, H; Zhang, XZ, 2017)
" In the CPIP acute phase, we observed mechanical and cold allodynia; increased levels of tumor necrosis factor-α (hind paw), ischemia-modified albumin (IMA) (serum), protein carbonyl (hind paw and spinal cord), lactate (serum), and 4-hydroxy-2-nonenal (4-HNE, hind paw and spinal cord); and higher myeloperoxidase (MPO) and N-acetyl-β-D-glucosaminidase (NAGase) activities (hind paw)."3.83Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms. ( Bochi, GV; da Silva, MA; de Prá, SD; Ferreira, J; Klafke, JZ; Moresco, RN; Rigo, FK; Rossato, MF; Trevisan, G; Walker, CI, 2016)
"In this study, blood redox potential (ORP) values (ΔORP value was adopted, as the quantitative index to reflect the overall redox status), plasma uric acid levels (important antioxidant, as antioxidant index), and the burn shock state-related indicators (lactic acid and hematocrit) of 48 burn patients were dynamically, quantitatively monitored during the early stage after injury."3.81The characteristics and correlation between the ischemia-reperfusion and changes of redox status in the early stage of severe burns. ( Han, C; Hu, H; Hu, X; Pan, X; Shao, H; Xu, J; Yu, C; Zhi, L, 2015)
"To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline."3.80Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats. ( Belon, AR; Carvalho, JG; Felice Neto, R; Marques, GM; Montero, EF; Rasslan, R; Rasslan, S; Utiyama, EM, 2014)
"Neuroprotective properties of the new derivative of glutamic and apovincaminic acids, ethyl -(3-alpha,16-alpha)-eburnamenin-14-carbopxylate of 2-aminopentadionic acid (LHT 1-02) were studied on a model of acute brain ischemia in cats."3.80[Effect of a new derivative of glutamic and apovincaminic acids on brain metabolism in post-ischemic period]. ( Makarova, LM; Mirzoian, RS; Pogorelyĭ, VE; Prikhod'ko, MA; Skachilova, SIa, 2014)
"The general anesthetic propofol protects the adult heart against ischemia and reperfusion injury; however, its efficacy has not been investigated in the immature heart."3.80Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes. ( Imura, H; Nitta, T; Shirakawa, M, 2014)
"It is well known that puerarin attenuates ischemia-reperfusion injury and promotes function recovery of ischemic region."3.79HP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats. ( Du, D; Jiang, CL; Li, MH; Liu, MF; Meng, Q; Peng, HS; Sun, SL; Tao, HQ; Wang, YM; Yang, HC; Yang, LZ; Ye, W; Yu, H; Zhu, DL, 2013)
"Flutamide failed to show any benefit to resuscitation in a model of severe injury and was associated with increased acidosis, hemodilution, and liver injury compared with standard crystalloid resuscitation."3.79Flutamide fails to reduce resuscitation requirements in a porcine ischemia-reperfusion model. ( Hempel, J; Hoffer, Z; Martin, M; Satterly, SA; Stallings, JD; Wingerd, M, 2013)
"To investigate the effects of preventive enteral administration of ornithine alpha-ketoglutarate (OKG) in an ischemia-reperfusion rat model."3.77Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. ( Garcia, JH; Gonçalves, ES; Guimarães, SB; Prado Neto, AX; Rabelo, CM; Vasconcelos, PR, 2011)
"To study the protective effects of lycopene (LP) on cerebral ischemia-reperfusion injury induced by focal cerebral ischemia and oxidative stress in rats."3.76[The effects of lycopene on reactive oxygen species and anoxic damage in ischemia reperfusion injury in rats]. ( Mai, JY; Shen, H; Shen, XN; Wang, RZ; Wei, Y; Wu, M, 2010)
"Using the middle cerebral artery occlusion model (MCAO) in rats and cerebral ischemia-reperfusion models in gerbils and mice, we investigated the influence of pueraria compound on the brain water content and the infarct size, the cerebral apoplexy exponent, the contents of lactic acid (LA) and lipid peroxide (LPO), the activities of lactic dehydrogenase (LDH), glutathione peroxidase (GPx) and Na+ -K+ -ATPase."3.73[Experimental study of protective effect of pueraria compound on the cerebral ischemic injury]. ( Cao, CY; Cui, HF; Du, GY; Wang, XR; Zhang, CY; Zhao, Y, 2005)
" In this study we evaluated the effect of global brain ischemia on brain metabolic parameters in normal and diabetic rats treated with a dihydropyridine calcium antagonist, felodipine."3.72The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers. ( Dunbar, JC; Levy, J; Zhu, Z, 2004)
" Trimetazidine (TMZ) has been reported to exert a protective action against normothermic ischemia and reperfusion injury in several experimental and clinical studies."3.70Efficiency of trimetazidine in renal dysfunction secondary to cold ischemia-reperfusion injury: a proposed addition to University of Wisconsin solution. ( Carretier, M; Eugene, M; Goujon, JM; Hauet, T; Tallineau, C; Tillement, JP, 1998)
"The authors prepared an experimental animal model of ischemia and reperfusion of the limbs to evaluate in vivo the reactive oxygen species involvement and protective role of coenzyme Q10 in reperfusion injury."3.69Protective role in vivo of coenzyme Q10 during reperfusion of ischemic limbs. ( Destito, C; Iacocagni, A; Littarru, GP; Marin, AW; Oradei, A; Romagnoli, A, 1994)
" Thirty-three patients underwent ILP with rhTNF alpha and melphalan for melanoma or soft-tissue sarcoma."3.69[O2 utilization during hyperthermic extremity perfusion with rhTNF alpha and melphalan]. ( Beck, K; Haier, J; Hohenberger, P; Schlag, PM, 1997)
"The effects of dichloroacetate (DCA) on brain lactate, intracellular pH (pHi), phosphocreatine (PCr), and ATP during 60 min of complete cerebral ischemia and 2 h of reperfusion were investigated in rats by in vivo 1H and 31P magnetic resonance spectroscopy; brain lactate, water content, cations, and amino acids were measured in vitro after reperfusion."3.68Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats. ( Abiko, H; Chang, LH; Faden, AI; James, TL; Shimizu, H; Swanson, RA; Weinstein, PR, 1992)
"Methylene blue (MB) has been used as a vasopressor in sepsis and acute liver failure."2.70The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation. ( Baumann, J; Bellamy, MC; Gedney, JA; Koelzow, H; Snook, NJ, 2002)
"Twelve pigs were subjected to hemorrhagic shock and 45 min of REBOA."1.91Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock. ( Ewer, N; Ford, R; Hoareau, GL; Johnson, MA; Neff, LP; Patel, N; Van Brocklin, MW; Vapniarsky, N; Williams, TK; Youngquist, ST, 2023)
"In this study, we used a global cerebral ischemia induced by four-vessel occlusion as an established animal model for ischemic stroke to investigate metabolic changes after 24 h reperfusion, when transitions occur due to the onset of delayed neuronal death."1.48NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia. ( Baranovicova, E; Cierny, D; Grendar, M; Kalenska, D; Lehotsky, J; Tomascova, A, 2018)
" In the present study, neuroprotective properties of creatylglycine ethyl ester fumarate (CrGEt) in rats with focal cerebral ischemia were explored in a wide dosage range (30-280 mg/kg, intravenous and intragastric)."1.42Neuroprotective activity of creatylglycine ethyl ester fumarate. ( Barygin, OI; Isaeva, AV; Korzhevskii, DE; Morozov, VA; Portsel, MN; Tihonov, DB; Veselkina, OS; Vlasov, TD, 2015)
"Acetylpuerarin (AP) is an acetylated derivative of puerarin (PUE)."1.42Polysorbate 80-coated PLGA nanoparticles improve the permeability of acetylpuerarin and enhance its brain-protective effects in rats. ( Lou, H; Shi, H; Sun, D; Xue, A; Zhang, B; Zhang, X, 2015)
"Histological features of ischaemia and reperfusion injury were assessed."1.40Comparison of energy metabolism in liver grafts from donors after circulatory death and donors after brain death during cold storage and reperfusion. ( Ahmed, N; Mirza, DF; Murphy, N; Neil, DA; Perera, MT; Richards, DA; Silva, MA, 2014)
"Global cerebral ischemia was established using the Pulsinelli four-vessel occlusion model and brain temperature was maintained at defined level for 60 min after 20-min ischemia."1.40Changes of c-fos, malondialdehyde and lactate in brain tissue after global cerebral ischemia under different brain temperatures. ( Li, L; Mei, YW; Murong, SX; Sun, SG; Tong, ET; Xu, GY; Zhang, H; Zhang, JJ, 2014)
"The prolonged hemorrhagic shock model was established by keeping the arterial blood pressure from 31 to 40 mmHg for 3 h through the femoral artery bleeding, and performing the resuscitation for 2 h by conventional fluid resuscitation and ECMO resuscitation, respectively."1.40Utilization of extracorporeal membrane oxygenation alleviates intestinal ischemia-reperfusion injury in prolonged hemorrhagic shock animal model. ( Chen, J; Jia, W; Luo, L; Xiao, J; Xiao, Y; Zhao, L, 2014)
"Ischemic myalgia is a unique type of muscle pain in the patient population."1.40Sensitization of group III and IV muscle afferents in the mouse after ischemia and reperfusion injury. ( Hudgins, RC; Jankowski, MP; Queme, LF; Ross, JL; Shank, AT, 2014)
"Glycerol continued to increase during initial reperfusion."1.37Continuous assessment of intrahepatic metabolism by microdialysis during and after portal triad clamping. ( Björnstedt, M; D'souza, MA; Isaksson, B; Jersenius, U; Lundell, L; Nowak, G; Permert, J; Ungerstedt, J, 2011)
"Some mechanisms of reperfusion injury are now recognized; they include oxygen free radical (OFR), white blood cells activation, changes in calcium influx, alteration of microvascular blood flow, and sympathetic activation."1.36Oxidative stress implication after prolonged storage donor heart with blood versus crystalloid cardioplegia and reperfusion versus static storage. ( Albertini, JP; Artigou, JY; Bonnefont-Rousselot, D; Charniot, JC; DeLattre, J; Dever, S; Monsuez, JJ; Nataf, P; Pavie, A; Vignat, N, 2010)
"Thoracoabdominal aortic aneurysm open surgery is accompanied by a significant incidence of renal failure due to renal ischemia."1.35Protective effect of remote ischemic preconditioning in renal ischemia/reperfusion injury, in a model of thoracoabdominal aorta approach. ( Charalambopoulos, A; Giamarellos-Bourboulis, EJ; Kakisis, JD; Karatzas, GM; Karkaletsis, KG; Lazaris, AM; Liakakos, TD; Maheras, AN; Martikos, G; Patapis, P; Vasdekis, SN, 2009)
" In order to reduce rat proteins to elicit possible immune responses in humans, we determined the effect of human AM combined with human AMBP-1 after intestinal ischemia and reperfusion (I/R)."1.35Human adrenomedullin combined with human adrenomedullin binding protein-1 is protective in gut ischemia and reperfusion injury in the rat. ( Blau, SA; Wang, P; Wu, R; Zhang, F; Zhou, M, 2009)
"Ischemia-reperfusion injury is a common pathological occurrence causing tissue damage in heart attack and stroke."1.35Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils. ( Arreola, J; Kaba, NK; Kim, M; Knauf, PA; Law, FY; Lefort, CT; Martel-Gallegos, G; Schultz, J; Waugh, RE, 2008)
"Propofol treatments, especially pre-treatment, significantly reduced Chiu's scores and levels of MDA, NO, ET-1 and LD, while restoring SOD activity."1.34Propofol attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in the rat. ( He, W; Liu, KX; Rinne, T; Wang, F; Xia, Z, 2007)
"These data suggest that reperfusion injury following asphyxia in the immature brain is associated with marked free radical production."1.33White matter injury following prolonged free radical formation in the 0.65 gestation fetal sheep brain. ( Arvidsson, P; Kjellmer, I; Lindblom, A; Mallard, C; Nilsson, UA; Sandberg, M; Welin, AK, 2005)
"Treatment with SB 203580, a p38 MAPK inhibitor, reduced intestinal apoptosis (26."1.33Inhibition of p38 mitogen-activated protein kinase may decrease intestinal epithelial cell apoptosis and improve intestinal epithelial barrier function after ischemia- reperfusion injury. ( Chen, W; Fu, XB; Sun, TZ; Xu, JG; Zhao, JY; Zheng, SY, 2005)
"Transient (2 hours) middle cerebral artery occlusion (MCAO) was performed in eight macaque monkeys."1.33Relationship between cerebral blood flow and oxygen metabolism, and extracellular glucose and lactate concentrations during middle cerebral artery occlusion and reperfusion: a microdialysis and positron emission tomography study in nonhuman primates. ( Enblad, P; Frykholm, P; Hillered, L; Långström, B; Persson, L; Valtysson, J, 2005)
"Incomplete cerebral ischemia induced was induced by ligating bilateral arteries carotis communis for 20 min followed by reperfusion 48 h in rats."1.33[Effects of paeoniflorin on cerebral energy metabolism, nitric oxide and nitric oxide synthase after cerebral ischemia in mongoliagerbils]. ( Liu, GQ; Lv, LL; Sun, R, 2006)
"This infarct-protective effect of remote IPC in LD muscle flaps was abolished by an intravenous bolus injection of the nonselective opioid receptor antagonist naloxone (3 mg/kg) 10 min before remote IPC and a continuous intravenous infusion (3 mg/kg) during remote IPC and by an intravenous bolus injection of the selective delta 1-opioid receptor antagonist 7-benzylidenealtrexone maleate (3 mg/kg)."1.32Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction. ( Addison, PD; Ashrafpour, H; Forrest, CR; Khan, A; Moses, M; Neligan, PC; Pang, CY; Zhong, A, 2003)
"Ischemia-reperfusion injury is a microvascular event documented in numerous in vivo animal models."1.32Human microvascular endothelial cell prostaglandin E1 synthesis during in vitro ischemia-reperfusion. ( Al-Badawi, H; Patton, GM; Peterson, B; Russo, AL; Soler, H; Watkins, MT, 2004)
"32 SD rats were randomly divided into four groups: normal group, model group, low dosage group, (treated with Astragalus membranaceus 10 g x kg(-1)); high dosage group (treated with Astragalus membranaceus 20 g x kg(-1))."1.32[Effects of Astragalus membranaceus injection on nitric oxide and endothelin concentration of intestinal mucosa after hemorrhage shock-reperfusion in rats]. ( Chen, BX; Hei, ZQ; Lin, SQ; Liu, KX; Zhang, JJ, 2004)
"Perhexiline is a potent prophylactic anti-anginal agent that has been shown to inhibit myocardial utilization of long-chain fatty acids and to inhibit the mitochondrial enzyme carnitine palmitoyltransferase (CPT)-1."1.31Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. ( Horowitz, JD; Kennedy, JA; Kiosoglous, AJ; Murphy, GA; Pelle, MA, 2000)
"Lactic acidosis has been implicated; however, increases in the excitotoxic amino acid glutamate, which correlate with increased neuronal damage, may be the cause for the increased damage seen in hyperglycemic stroke."1.31The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex. ( Diaz, FG; Guyot, LL; O'Regan, MH; Phillis, JW; Song, D, 2001)
"Focal cerebral ischemia-reperfusion resulted in abnormal behavior which could be alleviated by Sal B 10 mg."1.31Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats. ( Chen, YH; Du, GH; Zhang, JT, 2000)
"Transorbital 2 hour middle cerebral artery occlusion (MCAO) was performed in eight monkeys, which were studied with continuous microdialysis for 24 hours."1.31Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model. ( Enblad, P; Frykholm, P; Hillered, L; Långström, B; Persson, L; Valtysson, J; Watanabe, Y, 2001)
"In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models."1.31Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001)
" This study addresses the essential role of dosage in studies using C1-INH."1.31Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects. ( Berg, O; Bhakdi, S; Bierbach, B; Darius, H; Götze, O; Hafner, G; Heimann, A; Horstick, G; Horstick, M; Kempski, O; Loos, M; Meyer, J; Petersen, S, 2001)
"The focal cerebral ischemia was produced by the occlusion of the right common carotid artery and the right middle cerebral artery for 60 mins."1.31Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. ( Cheng, FC; Chung, SY; Lin, JY; Lin, MC, 2002)
"Phosphoenolpyruvate (PEP) is a high-energy metabolite in the final step of glycolysis."1.30Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats. ( Chijiiwa, K; Hamasaki, N; Saiki, S; Shimizu, S; Tanaka, M; Yamaguchi, K, 1997)
"Cerebral ischemia was induced, using the bilateral carotid artery occlusion method, for 20 or 60 min, followed by reperfusion up to 120 min."1.30The effect of duration of cerebral ischemia on brain pyruvate dehydrogenase activity, energy metabolites, and blood flow during reperfusion in gerbil brain. ( Fukuchi, T; Kamiya, T; Kashiwagi, F; Katayama, Y; McKee, A; Terashi, A, 1998)
"The clues of reperfusion injury do not become evident following detorsion of testicular torsion lasting more than 6 hours."1.29Ipsilateral and contralateral testicular biochemical acute changes after unilateral testicular torsion and detorsion. ( Akgür, FM; Büyükpamukçu, N; Hiçsönmez, A; Kilinç, K; Tanyel, FC, 1994)
"As unilateral testicular torsion and varicocele have been shown to affect contralateral testicular blood flow, reperfusion injury was studied in both testes."1.29Reperfusion injury after detorsion of unilateral testicular torsion. ( Akgür, FM; Aktuğ, T; Kilinç, K, 1993)

Research

Studies (203)

TimeframeStudies, this research(%)All Research%
pre-19902 (0.99)18.7374
1990's39 (19.21)18.2507
2000's87 (42.86)29.6817
2010's66 (32.51)24.3611
2020's9 (4.43)2.80

Authors

AuthorsStudies
Schurink, IJ1
de Haan, JE1
Willemse, J1
Mueller, M1
Doukas, M1
Roest, H1
de Goeij, FHC1
Polak, WG1
Ijzermans, JNM1
Dutkowski, P2
van der Laan, LJW1
de Jonge, J1
Uzdenov, M1
Kaisinova, A1
Fedorov, A1
Mairansaeva, S1
Еmkuzhеv, К1
Patel, N1
Johnson, MA2
Vapniarsky, N1
Van Brocklin, MW1
Williams, TK2
Youngquist, ST1
Ford, R1
Ewer, N1
Neff, LP2
Hoareau, GL2
Zhao, Y2
Gao, J1
Li, C3
Song, G1
Shan, Y1
Takata, T1
Nonaka, W1
Iwama, H1
Kobara, H1
Deguchi, K1
Masugata, H1
Touge, T1
Miyamoto, O1
Nakamura, T2
Itano, T1
Masaki, T1
Lonati, C1
Battistin, M1
Dondossola, DE1
Bassani, GA1
Brambilla, D1
Merighi, R1
Leonardi, P1
Carlin, A1
Meroni, M1
Zanella, A1
Catania, A1
Gatti, S1
Verhaar, N1
de Buhr, N1
von Köckritz-Blickwede, M1
Hewicker-Trautwein, M1
Pfarrer, C1
Mazzuoli-Weber, G1
Schulte, H1
Kästner, S1
Annoni, F1
Peluso, L1
Gouvêa Bogossian, E1
Creteur, J1
Zanier, ER1
Taccone, FS1
Conner, J1
Lammers, D1
Holtestaul, T1
Jones, I1
Kuckelman, J1
Letson, H1
Dobson, G1
Eckert, M1
Bingham, J1
Gregorini, M1
Corradetti, V1
Pattonieri, EF1
Rocca, C1
Milanesi, S1
Peloso, A1
Canevari, S1
De Cecco, L1
Dugo, M1
Avanzini, MA1
Mantelli, M1
Maestri, M1
Esposito, P1
Bruno, S1
Libetta, C1
Dal Canton, A1
Rampino, T1
Peoc'h, K1
Nuzzo, A1
Guedj, K1
Paugam, C1
Corcos, O1
Kisu, I1
Umene, K1
Adachi, M1
Emoto, K1
Nogami, Y1
Banno, K1
Itagaki, I1
Kawamoto, I1
Nakagawa, T1
Narita, H1
Yoshida, A1
Tsuchiya, H1
Ogasawara, K1
Aoki, D1
Luo, YP1
Zhang, H3
Hu, HF1
Cao, ZY1
Zhang, XZ1
Cao, L1
Wang, ZZ1
Xiao, W1
Baranovicova, E1
Grendar, M1
Kalenska, D1
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Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Single-blinded Placebo-controlled Trial of Ischemic Preconditioning in Raynaud's Phenomenon (RP)[NCT02506062]21 participants (Actual)Interventional2015-07-31Completed
Randomized Triple-blind Placebo Controlled Trial of Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival and Neurological Outcome[NCT04009759]Phase 1240 participants (Anticipated)Interventional2021-10-01Not yet recruiting
Remote Ischemic Preconditioning in Head and Neck Cancer Reconstruction - A Randomized Controlled Trial[NCT02548377]60 participants (Actual)Interventional2015-09-29Completed
Evaluation of Microdialysis to Monitor Postoperative Outcomes After Proctectomy[NCT01999634]Phase 321 participants (Actual)Interventional2014-02-05Completed
Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103]30 participants (Actual)Interventional2018-02-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for lactic acid and Reperfusion Injury

ArticleYear
Brain Protection after Anoxic Brain Injury: Is Lactate Supplementation Helpful?
    Cells, 2021, 07-06, Volume: 10, Issue:7

    Topics: Acidosis; Animals; Brain Injuries, Traumatic; Cell Death; Cerebrovascular Circulation; Energy Metabo

2021
Diagnosis biomarkers in acute intestinal ischemic injury: so close, yet so far.
    Clinical chemistry and laboratory medicine, 2018, 02-23, Volume: 56, Issue:3

    Topics: Acute Disease; Biomarkers; Citrulline; Fatty Acid-Binding Proteins; Humans; Intestines; Lactic Acid;

2018
Concerning the importance of changes in hemorheological parameters caused by acid-base and blood gas alterations in experimental surgical models.
    Clinical hemorheology and microcirculation, 2012, Volume: 51, Issue:1

    Topics: Acid-Base Equilibrium; Animals; Disease Models, Animal; Erythrocyte Deformability; Gases; Hemorheolo

2012
Fatty acid oxidation in the heart.
    Journal of cardiovascular pharmacology, 1996, Volume: 28 Suppl 1

    Topics: Adenosine Triphosphate; Animals; Calcium; Fatty Acids; Fish Oils; Humans; Lactic Acid; Mitochondria,

1996

Trials

10 trials available for lactic acid and Reperfusion Injury

ArticleYear
Ischaemic postconditioning reduces apoptosis in experimental jejunal ischaemia in horses.
    BMC veterinary research, 2021, Apr-26, Volume: 17, Issue:1

    Topics: Animals; Apoptosis; Horses; HSP70 Heat-Shock Proteins; Intestinal Mucosa; Ischemic Postconditioning;

2021
Remote ischaemic preconditioning down-regulates kinin receptor expression in neutrophils of patients undergoing heart surgery.
    Interactive cardiovascular and thoracic surgery, 2013, Volume: 17, Issue:4

    Topics: Aged; Biomarkers; Bradykinin; C-Reactive Protein; Cardiopulmonary Bypass; Coronary Artery Bypass; Cr

2013
Comparison of the effect of propofol and N-acetyl cysteine in preventing ischaemia-reperfusion injury.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Blood Gas Ana

2009
Erythropoietin ameliorates early ischemia-reperfusion injury following the Pringle maneuver.
    World journal of gastroenterology, 2010, Oct-14, Volume: 16, Issue:38

    Topics: Aged; Animals; Digestive System Surgical Procedures; Erythropoietin; Female; Hematocrit; Hemoglobins

2010
Transhepatic lactate gradient in relation to liver ischemia/reperfusion injury during major hepatectomies.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2006, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Biomarkers; Female; Hepatectomy; Humans; Lactic Acid; Liver; Liver Circulat

2006
Sevoflurane but not propofol increases interstitial glycolysis metabolites availability during tourniquet-induced ischaemia-reperfusion.
    British journal of anaesthesia, 2008, Volume: 100, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Glucose;

2008
The reflush effect--a prospective analysis of late perfusion.
    Transplantation, 1993, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Coagulation; Calcium; Female; Follow-Up Studies; Humans; Hydrogen-Ion

1993
Low-dose dopexamine in patients undergoing hemihepatectomy: an evaluation of effects on reduction of hepatic dysfunction and ischaemic liver injury.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:4

    Topics: Adult; Aged; Antithrombin III; Dopamine; Dopamine Agonists; Double-Blind Method; Female; Hemodynamic

2000
Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1.
    British journal of anaesthesia, 2000, Volume: 85, Issue:3

    Topics: Aged; Alprostadil; Amrinone; Analysis of Variance; Female; Hepatectomy; Humans; Indocyanine Green; L

2000
The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Cyclic GMP; Enzyme Inhibitors; Female; Guan

2002

Other Studies

189 other studies available for lactic acid and Reperfusion Injury

ArticleYear
A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion.
    Scientific reports, 2021, 12-06, Volume: 11, Issue:1

    Topics: Adult; Aged; Cold Ischemia; Cytochrome P-450 CYP1A2; Graft Survival; Humans; Lactic Acid; Liver; Liv

2021
[EVALUATION OF SYSTEMIC PRO-INFLAMMATORY REACTIONS IN SIMULATING REVERSIBLE OCCLUSION OF ANTERIOR MESENTERIC ARTERY TO JUSTIFY MEDICAL REHABILITATION].
    Georgian medical news, 2022, Issue:324

    Topics: Animals; Humans; Ischemia; Lactic Acid; Mesenteric Arteries; Rats; Reperfusion Injury; Tumor Necrosi

2022
Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock.
    Scientific reports, 2023, 03-18, Volume: 13, Issue:1

    Topics: Animals; Balloon Occlusion; Disease Models, Animal; Endovascular Procedures; Hemorrhage; Lactic Acid

2023
MILD THERAPEUTIC HYPOTHERMIA REDUCES ISCHEMIA-REPERFUSION INJURY AFTER ZONE 1 REBOA IN A SWINE HEMORRHAGIC SHOCK MODEL.
    Shock (Augusta, Ga.), 2023, 09-01, Volume: 60, Issue:3

    Topics: Animals; Aorta; Balloon Occlusion; Disease Models, Animal; Hypothermia; Hypothermia, Induced; Lactic

2023
Light exercise without lactate elevation induces ischemic tolerance through the modulation of microRNA in the gerbil hippocampus.
    Brain research, 2020, 04-01, Volume: 1732

    Topics: Animals; Brain Ischemia; Gene Expression Regulation; Gerbillinae; Hippocampus; Lactic Acid; Male; Me

2020
NDP-MSH treatment recovers marginal lungs during ex vivo lung perfusion (EVLP).
    Peptides, 2021, Volume: 141

    Topics: Adenosine Triphosphate; alpha-MSH; Animals; Death; Hyaluronic Acid; Inflammation Mediators; Lactic A

2021
Combatting ischemia reperfusion injury from resuscitative endovascular balloon occlusion of the aorta using adenosine, lidocaine and magnesium: A pilot study.
    The journal of trauma and acute care surgery, 2021, 12-01, Volume: 91, Issue:6

    Topics: Adenosine; Animals; Anti-Inflammatory Agents; Aorta; Balloon Occlusion; Disease Models, Animal; Drug

2021
Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:12

    Topics: Adenosine; Allopurinol; Animals; Biomarkers; Energy Metabolism; Extracellular Vesicles; Gene Express

2017
Allowable warm ischemic time and morphological and biochemical changes in uterine ischemia/reperfusion injury in cynomolgus macaque: a basic study for uterus transplantation.
    Human reproduction (Oxford, England), 2017, 10-01, Volume: 32, Issue:10

    Topics: Acid-Base Equilibrium; Animals; Blood Gas Analysis; Female; Humans; Infertility, Female; Lactic Acid

2017
[Protective effects of Ginkgo Terpene Lactones Meglumine Injection on focal cerebral ischemia in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:24

    Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Creatine Kinase, BB Form; Ginkgo biloba; Glutamic A

2017
NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:3

    Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine

2018
Synergistic effects of ischemic preconditioning and immediate post-conditioning in the protection against ischemia/reperfusion injury in rabbit submandibular glands.
    European journal of oral sciences, 2018, Volume: 126, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling;

2018
Endovascular variable aortic control (EVAC) versus resuscitative endovascular balloon occlusion of the aorta (REBOA) in a swine model of hemorrhage and ischemia reperfusion injury.
    The journal of trauma and acute care surgery, 2018, Volume: 85, Issue:3

    Topics: Animals; Aorta; Balloon Occlusion; Disease Models, Animal; Endovascular Procedures; Female; Hemodyna

2018
Aortic branch vessel flow during resuscitative endovascular balloon occlusion of the aorta.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:1

    Topics: Animals; Aorta; Arteries; Balloon Occlusion; Blood Flow Velocity; Disease Models, Animal; Endovascul

2019
A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation.
    Journal of visualized experiments : JoVE, 2019, 04-27, Issue:146

    Topics: Animals; Disease Models, Animal; Electrocardiography; Heart Transplantation; Hydrogen-Ion Concentrat

2019
Early detection of gut ischemia-reperfusion injury during aortic abdominal aneurysmectomy: a pilot, observational study.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Aneurysm, Ruptured; Aortic Aneurysm, Abdominal; Carbon Dioxide; Colon; Constriction; Female; H

2013
[The timing of infusion of hypertonic saline to exert protective effect on intestinal barrier function in the rabbit with intestinal ischemia/reperfusion injury].
    Zhonghua wei zhong bing ji jiu yi xue, 2013, Volume: 25, Issue:6

    Topics: Animals; Female; Interleukin-10; Intestinal Mucosa; Intestines; Lactic Acid; Male; Rabbits; Reperfus

2013
Flutamide fails to reduce resuscitation requirements in a porcine ischemia-reperfusion model.
    The Journal of surgical research, 2013, Volume: 184, Issue:1

    Topics: Acidosis; Androgen Antagonists; Animals; Crystalloid Solutions; Cyclodextrins; Disease Models, Anima

2013
Bone-marrow mesenchymal stem cells reduce rat intestinal ischemia-reperfusion injury, ZO-1 downregulation and tight junction disruption via a TNF-α-regulated mechanism.
    World journal of gastroenterology, 2013, Jun-21, Volume: 19, Issue:23

    Topics: Amine Oxidase (Copper-Containing); Animals; Biomarkers; Bone Marrow Transplantation; Cells, Cultured

2013
Low-dose vasopressin improves cardiac function in newborn piglets with acute hypoxia-reoxygenation.
    Shock (Augusta, Ga.), 2013, Volume: 40, Issue:4

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cardiac Output; Dobutamine; Glutathione; Heart Ventr

2013
Effect of large colon ischemia and reperfusion on concentrations of calprotectin and other clinicopathologic variables in jugular and colonic venous blood in horses.
    American journal of veterinary research, 2013, Volume: 74, Issue:10

    Topics: Acidosis; Animals; Blood Gas Analysis; Colon; Creatine Kinase; Enzyme-Linked Immunosorbent Assay; He

2013
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
    Disease markers, 2013, Volume: 35, Issue:5

    Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophos

2013
Microcirculatory perfusion shift in the gut wall layers induced by extracorporeal circulation.
    Journal of vascular surgery, 2015, Volume: 61, Issue:2

    Topics: Acidosis, Lactic; Animals; Aorta, Thoracic; Blood Flow Velocity; Constriction; Extracorporeal Circul

2015
Renal cortical pyruvate depletion during AKI.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:5

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Gluconeogenesis; Glucose; Glycogen; Hydrogen P

2014
Pyruvate-enriched resuscitation: metabolic support of post-ischemic hindlimb muscle in hypovolemic goats.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:2

    Topics: Animals; Antioxidants; Citric Acid; Dinoprost; Goats; Hypovolemia; Infusions, Intravenous; Lactic Ac

2014
[The protective effect of asiatic acid against oxygen-glucose deprivation/reoxygenation injury of PC12 cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:11

    Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Centella; Dose-Response Relationship, Drug; Glucose; L

2013
Comparison of energy metabolism in liver grafts from donors after circulatory death and donors after brain death during cold storage and reperfusion.
    The British journal of surgery, 2014, Volume: 101, Issue:7

    Topics: Adult; Aged; Brain Death; Cryopreservation; Energy Metabolism; Glycerol; Graft Survival; Heart Arres

2014
[Effect of a new derivative of glutamic and apovincaminic acids on brain metabolism in post-ischemic period].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:2

    Topics: Acidosis, Lactic; Animals; Blood Glucose; Brain; Brain Ischemia; Cats; Glutamic Acid; Glycine; Lacti

2014
Changes of c-fos, malondialdehyde and lactate in brain tissue after global cerebral ischemia under different brain temperatures.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2014, Volume: 34, Issue:3

    Topics: Animals; Body Temperature; Brain; Brain Ischemia; Cerebral Cortex; Hippocampus; Immunochemistry; Lac

2014
Utilization of extracorporeal membrane oxygenation alleviates intestinal ischemia-reperfusion injury in prolonged hemorrhagic shock animal model.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3

    Topics: Animals; Blood Pressure; Claudin-1; Disease Models, Animal; Extracorporeal Membrane Oxygenation; Int

2014
Protection against intestinal injury from hemorrhagic shock by direct peritoneal resuscitation with pyruvate in rats.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:5

    Topics: Animals; Dialysis Solutions; Drug Evaluation, Preclinical; Fluid Therapy; Inflammation Mediators; In

2014
Metabolic properties in stroked rats revealed by relaxation-enhanced magnetic resonance spectroscopy at ultrahigh fields.
    Nature communications, 2014, Sep-17, Volume: 5

    Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Ischemia; Lactic Acid; Magnetic Fields; Magnetic

2014
Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Cyclosporine; Heart; Hemodynamics; Lactic Acid; Myocardium; Propofol; Protective Agents; Ra

2014
Sensitization of group III and IV muscle afferents in the mouse after ischemia and reperfusion injury.
    The journal of pain, 2014, Volume: 15, Issue:12

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Disease Models, Animal; Forelimb; Ganglia, Spina

2014
Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats.
    Acta cirurgica brasileira, 2014, Volume: 29, Issue:11

    Topics: Animals; Apoptosis; Caspase 3; Cyclooxygenase 2; Immunohistochemistry; Intestines; Ischemia; Lactic

2014
The characteristics and correlation between the ischemia-reperfusion and changes of redox status in the early stage of severe burns.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Adult; Burns; Case-Control Studies; Cohort Studies; Disease Progression; Hematocrit; Humans; Hypoxia

2015
Neuroprotective activity of creatylglycine ethyl ester fumarate.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:3

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Behavior, Animal; Brain; Cell Survival; Creatine Kina

2015
Metabolic shift in liver: correlation between perfusion temperature and hypoxia inducible factor-1α.
    World journal of gastroenterology, 2015, Jan-28, Volume: 21, Issue:4

    Topics: Animals; Cold Temperature; Energy Metabolism; Glycogen; Hypoxia-Inducible Factor 1, alpha Subunit; I

2015
The influence of extracorporeal membrane oxygenation therapy on intestinal mucosal barrier in a porcine model for post-traumatic acute respiratory distress syndrome.
    Journal of cardiothoracic surgery, 2015, Feb-15, Volume: 10

    Topics: Animals; Disease Models, Animal; Extracorporeal Membrane Oxygenation; Fatty Acid-Binding Proteins; F

2015
Exendin-4-loaded PLGA microspheres relieve cerebral ischemia/reperfusion injury and neurologic deficits through long-lasting bioactivity-mediated phosphorylated Akt/eNOS signaling in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:11

    Topics: Animals; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Cognition

2015
Polysorbate 80-coated PLGA nanoparticles improve the permeability of acetylpuerarin and enhance its brain-protective effects in rats.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:12

    Topics: Animals; Apoptosis; Area Under Curve; Biotransformation; Blood-Brain Barrier; Brain; Brain Injuries;

2015
Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms.
    Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:2

    Topics: Acetylglucosaminidase; Acute Pain; Aldehydes; Animals; Chronic Pain; Cold Temperature; Hindlimb; Hyp

2016
PFKFB3-mediated glycolysis is involved in reactive astrocyte proliferation after oxygen-glucose deprivation/reperfusion and is regulated by Cdh1.
    Neurochemistry international, 2015, Volume: 91

    Topics: Animals; Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome; Astrocytes; Cadherins; Cell Hypoxia; Ce

2015
Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Antioxidants; Dinoprost; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fatty A

2016
Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation.
    Scientific reports, 2016, 07-11, Volume: 6

    Topics: Administration, Intravenous; Animals; Biphenyl Compounds; Cardiotonic Agents; Disease Models, Animal

2016
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
    American journal of physiology. Renal physiology, 2017, 03-01, Volume: 312, Issue:3

    Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An

2017
Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:5

    Topics: Amiloride; Ammonium Chloride; CD11b Antigen; CD18 Antigens; Cell Membrane; Guanidines; Humans; Hydro

2008
Human adrenomedullin combined with human adrenomedullin binding protein-1 is protective in gut ischemia and reperfusion injury in the rat.
    Regulatory peptides, 2009, Jan-08, Volume: 152, Issue:1-3

    Topics: Adrenomedullin; Alanine Transaminase; Animals; Aspartate Aminotransferases; Complement Factor H; Cyt

2009
Albumin resuscitation protects against traumatic/hemorrhagic shock-induced lung apoptosis in rats.
    Journal of Zhejiang University. Science. B, 2008, Volume: 9, Issue:11

    Topics: Albumins; Animals; Apoptosis; Enzyme Activation; Immunohistochemistry; In Situ Nick-End Labeling; La

2008
Fructose-1,6-bisphosphate and fructose-2,6-bisphosphate do not influence brain carbohydrate or high-energy phosphate metabolism in a rat model of forebrain ischemia.
    Journal of neurosurgical anesthesiology, 2009, Volume: 21, Issue:1

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthe

2009
Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:5

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Cerebral Infarction; Lactic Acid; Male; Nanopar

2009
Physiologically relevant online electrochemical method for continuous and simultaneous monitoring of striatum glucose and lactate following global cerebral ischemia/reperfusion.
    Analytical chemistry, 2009, Mar-15, Volume: 81, Issue:6

    Topics: Animals; Biosensing Techniques; Brain Ischemia; Carbon; Corpus Striatum; Electrochemical Techniques;

2009
Glutathione and amino acid concentrations in human liver during short warm ischaemia and reperfusion: a pilot study.
    Clinical science (London, England : 1979), 2009, Sep-01, Volume: 117, Issue:9

    Topics: Adult; Aged; Amino Acids; Female; Glutathione; Hepatectomy; Humans; Intraoperative Care; Lactic Acid

2009
Protective effect of remote ischemic preconditioning in renal ischemia/reperfusion injury, in a model of thoracoabdominal aorta approach.
    The Journal of surgical research, 2009, Jun-15, Volume: 154, Issue:2

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Disease Models, An

2009
Hematological responses of the grey carpet shark (Chiloscyllium punctatum) and the epaulette shark (Hemiscyllium ocellatum) to anoxia and re-oxygenation.
    Journal of experimental zoology. Part A, Ecological genetics and physiology, 2009, Jul-01, Volume: 311, Issue:6

    Topics: Adaptation, Physiological; Animals; Blood Glucose; Disease Models, Animal; Erythrocyte Count; Hemato

2009
Oxidative stress implication after prolonged storage donor heart with blood versus crystalloid cardioplegia and reperfusion versus static storage.
    The Journal of surgical research, 2010, May-15, Volume: 160, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; beta Carotene; Blood Transfusion, Autologous; Cryopreservation; Gluta

2010
The protective effect of oxygenated perfluorocarbons (PFCs) on intestinal ischemia reperfusion injury (I/R) in rabbits.
    Vascular and endovascular surgery, 2010, Volume: 44, Issue:2

    Topics: Animals; Cell Survival; Cytoprotection; Disease Models, Animal; Fluorocarbons; Infusions, Parenteral

2010
[Ishemic-reperfusion syndrome prophylaxis in general hypothermia in experiment].
    Klinichna khirurhiia, 2009, Issue:5

    Topics: Animals; Antioxidants; Body Temperature; Catalase; Female; Glucose; Glutathione; Homeostasis; Hypoth

2009
Exogenous modulation of intrinsic optic nerve neuroprotective activity.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:8

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Ciliary Neurotrophic Factor; Disease Mode

2010
Continuous assessment of intrahepatic metabolism by microdialysis during and after portal triad clamping.
    The Journal of surgical research, 2011, Volume: 169, Issue:2

    Topics: Adult; Aged; Biomarkers; Constriction; Feasibility Studies; Female; Glucose; Glycerol; Hepatectomy;

2011
[The effects of lycopene on reactive oxygen species and anoxic damage in ischemia reperfusion injury in rats].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2010, Volume: 44, Issue:1

    Topics: Animals; Antioxidants; Brain Ischemia; Carotenoids; Hippocampus; Infarction, Middle Cerebral Artery;

2010
Partial liver ischemia is followed by metabolic changes in the normally perfused part of the liver during reperfusion.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2010, Volume: 45, Issue:2

    Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Glucose; Glycerol; Humans; Ischemia;

2010
[Effects of lactate on cell injury in primary cultures of rat cortical neurons during hypoxia/reoxygenation].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:4

    Topics: Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Lactic Acid; Neurons; Neu

2008
The impact of deep and moderate body temperatures on end-organ function during hypothermic circulatory arrest.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 40, Issue:6

    Topics: Animals; Biomarkers; Body Temperature; Carbon Dioxide; Cardiopulmonary Bypass; Cerebrovascular Circu

2011
Hemoglobin vesicle improves recovery of cardiac function after ischemia-reperfusion by attenuating oxidative stress in isolated rat hearts.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:5

    Topics: Animals; Blood Substitutes; Catalase; Coronary Circulation; Glutathione; Glutathione Disulfide; Glut

2011
Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats.
    Acta cirurgica brasileira, 2011, Volume: 26 Suppl 1

    Topics: Animals; Calcium Carbonate; Disease Models, Animal; Intestinal Diseases; Intestine, Small; Ischemia;

2011
Preconditioning with L-alanyl-L-glutamine in a Mongolian gerbil model of acute cerebral ischemia/reperfusion injury.
    Acta cirurgica brasileira, 2011, Volume: 26 Suppl 1

    Topics: Animals; Blood Glucose; Brain Ischemia; Dipeptides; Disease Models, Animal; Gerbillinae; Ischemic Pr

2011
N-acetyl cysteine improves glycogenesis after segmental liver ischemia and reperfusion injury in pigs.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Analysis of Variance; Animals; Apoptosis; Aspartate Aminotra

2012
Single injection of ONO-1301-loaded PLGA microspheres directly after ischaemia reduces ischaemic damage in rats subjected to middle cerebral artery occlusion.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:3

    Topics: Animals; Biocompatible Materials; Epoprostenol; Infarction, Middle Cerebral Artery; Injections, Subc

2012
[The protective effects of bifidobacterial adhesin on ischemic reperfusion injury of intestine in rats].
    Zhonghua nei ke za zhi, 2011, Volume: 50, Issue:10

    Topics: Adhesins, Bacterial; Animals; Bifidobacterium; D-Amino-Acid Oxidase; Interleukin-10; Interleukin-6;

2011
Dexmedetomidine administration before, but not after, ischemia attenuates intestinal injury induced by intestinal ischemia-reperfusion in rats.
    Anesthesiology, 2012, Volume: 116, Issue:5

    Topics: Adrenergic alpha-Agonists; Amine Oxidase (Copper-Containing); Animals; Apoptosis; Blood Gas Analysis

2012
Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation.
    Shock (Augusta, Ga.), 2012, Volume: 38, Issue:4

    Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Caspase 3; Dinoprost; Endothelin-1; Enzyme Ac

2012
Dynamic alteration of the colonic microbiota in intestinal ischemia-reperfusion injury.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Biodiversity; Colon; Intestinal Mucosa; Lactic Acid; Male; Metagenome; Rats; Rats, Sprague-

2012
Cuff width increases the serum biochemical markers of tourniquet-induced skeletal muscle ischemia in rabbits.
    Orthopedics, 2012, Aug-01, Volume: 35, Issue:8

    Topics: Animals; Biomarkers; Creatine Kinase, MM Form; Ischemia; L-Lactate Dehydrogenase; Lactic Acid; Muscl

2012
[Diagnostics and treatment of the ischemic and reperfusion disorders by the intraabdominal ischemic syndrome].
    Khirurgiia, 2012, Issue:7

    Topics: Abdominal Cavity; Adult; Algorithms; Animals; Combined Modality Therapy; Decompression, Surgical; Fe

2012
HP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Biological Availability; Blood-Brain

2013
Ischemic postconditioning during reperfusion attenuates oxidative stress and intestinal mucosal apoptosis induced by intestinal ischemia/reperfusion via aldose reductase.
    Surgery, 2013, Volume: 153, Issue:4

    Topics: Aldehyde Reductase; Amine Oxidase (Copper-Containing); Animals; Apoptosis; Enzyme Inhibitors; Ileum;

2013
Methylene blue protects liver oxidative capacity after gut ischaemia-reperfusion in the rat.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2013, Volume: 45, Issue:2

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Biomarkers; Cytoprotection; D

2013
Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI3K/Akt pathway.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:4

    Topics: Animals; Brain Edema; Brain Infarction; Chromones; Energy Metabolism; Enzyme Inhibitors; L-Lactate D

2013
Novel multiple agents loaded PLGA nanoparticles for brain delivery via inner ear administration: in vitro and in vivo evaluation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Mar-12, Volume: 48, Issue:4-5

    Topics: Abietanes; Animals; Benzofurans; Brain; Carotid Arteries; Drug Administration Routes; Drug Carriers;

2013
The influence of apoptosis of mucosal epithelial cells on intestinal barrier integrity after scald in rats.
    Burns : journal of the International Society for Burn Injuries, 2002, Volume: 28, Issue:8

    Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Burns; DNA Fragmentation; Electrophoresis, Ag

2002
Kinetics of endotoxin concentration and tumor necrosis factor-alpha, interleukin-1beta, and interleukin-6 activities in the systemic and portal circulation during small intestinal ischemia and reperfusion in dogs.
    American journal of veterinary research, 2002, Volume: 63, Issue:12

    Topics: Animals; Biological Assay; Cytotoxicity Tests, Immunologic; Dog Diseases; Dogs; Endotoxins; Female;

2002
Calcium prevents loss of glutathione and reduces oxidative stress upon reperfusion in the perfused liver.
    International journal of surgical investigation, 2000, Volume: 2, Issue:1

    Topics: Animals; Calcium; Energy Metabolism; Glutathione; Hypothermia, Induced; In Vitro Techniques; L-Lacta

2000
Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:4

    Topics: Abdomen; Adenosine Triphosphate; Animals; Ganglionic Blockers; Hexamethonium; Hindlimb; Infarction;

2003
Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:4

    Topics: Abdomen; Adenosine Triphosphate; Animals; Ganglionic Blockers; Hexamethonium; Hindlimb; Infarction;

2003
Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:4

    Topics: Abdomen; Adenosine Triphosphate; Animals; Ganglionic Blockers; Hexamethonium; Hindlimb; Infarction;

2003
Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:4

    Topics: Abdomen; Adenosine Triphosphate; Animals; Ganglionic Blockers; Hexamethonium; Hindlimb; Infarction;

2003
Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium.
    Peptides, 2003, Volume: 24, Issue:4

    Topics: Animals; Area Under Curve; Blood Glucose; Cardiovascular System; Glucagon; Glucagon-Like Peptide 1;

2003
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting,

2004
Gut barrier dysfunction as detected by intestinal luminal microdialysis.
    Intensive care medicine, 2004, Volume: 30, Issue:6

    Topics: Analysis of Variance; Animals; Biomarkers; Glucose; Glycerol; Intestinal Absorption; Intestinal Muco

2004
The effect of hyperglycemia on experimental retinal ischemia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:3

    Topics: Animals; Blood Glucose; Cyclophilins; Deoxyglucose; Diabetes Mellitus, Experimental; Electroretinogr

2004
Human microvascular endothelial cell prostaglandin E1 synthesis during in vitro ischemia-reperfusion.
    Journal of cellular biochemistry, 2004, Jun-01, Volume: 92, Issue:3

    Topics: Alprostadil; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelium

2004
Splanchnic metabolism during gut ischemia and short-term endotoxin and hemorrhagic shock as evaluated by intravasal microdialysis.
    Shock (Augusta, Ga.), 2004, Volume: 21, Issue:6

    Topics: Abdomen; Animals; Endotoxemia; Endotoxins; Glucose; Glycerol; Hemodynamics; Ileum; Ischemia; Lactic

2004
Effects of norepinephrine depletion in rats during cerebral post-ischemic reperfusion.
    Neurotoxicology, 2004, Volume: 25, Issue:5

    Topics: Animals; Benzylamines; Brain Chemistry; Brain Injuries; Brain Ischemia; Cerebral Cortex; Coloring Ag

2004
[Effects of acidic fibroblast growth factor on intestinal mucosal damage due to ischemia/reperfusion].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2004, Volume: 16, Issue:8

    Topics: Animals; Disease Models, Animal; Fibroblast Growth Factor 1; Intestinal Mucosa; Lactic Acid; Random

2004
Glutamine supplemented parenteral nutrition prevents intestinal ischemia- reperfusion injury in rats.
    World journal of gastroenterology, 2004, Sep-01, Volume: 10, Issue:17

    Topics: Animals; Atrophy; Bacterial Translocation; Glutamine; Intestinal Mucosa; Intestines; Lactic Acid; Ma

2004
Limb ischemia and reperfusion during abdominal aortic aneurysm surgery.
    Surgery today, 2004, Volume: 34, Issue:10

    Topics: Aged; Aortic Aneurysm, Abdominal; Female; Humans; Hydrogen-Ion Concentration; Iliac Artery; Ischemia

2004
[Protective effects of modified recombinant human acidic fibroblast growth factor on small intestine after ischemia/reperfusion injury in rats].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2005, Volume: 17, Issue:1

    Topics: Animals; Apoptosis; Disease Models, Animal; Epithelial Cells; Fibroblast Growth Factor 1; Humans; In

2005
Inhibition of p38 mitogen-activated protein kinase may decrease intestinal epithelial cell apoptosis and improve intestinal epithelial barrier function after ischemia- reperfusion injury.
    World journal of gastroenterology, 2005, Feb-07, Volume: 11, Issue:5

    Topics: Animals; Apoptosis; Biological Transport; Enzyme Inhibitors; Imidazoles; Intestinal Mucosa; Lactic A

2005
Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway.
    Journal of cellular physiology, 2005, Volume: 204, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Connexin 43; Electric Conductivity; Endothelial Ce

2005
[Protective effects of acidic fibroblast growth factor on intestinal ischemia/reperfusion in rats].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2005, Volume: 17, Issue:2

    Topics: Animals; Disease Models, Animal; Fibroblast Growth Factor 1; Humans; Intestines; Lactic Acid; Male;

2005
[Effects of Astragalus membranaceus injection on nitric oxide and endothelin concentration of intestinal mucosa after hemorrhage shock-reperfusion in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:5

    Topics: Animals; Astragalus propinquus; Drugs, Chinese Herbal; Endothelins; Ileum; Injections, Intravenous;

2004
The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers.
    Endocrine, 2004, Volume: 25, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain Chemistry; Brain Ischemia; Calcium; Calcium Channel Blockers;

2004
White matter injury following prolonged free radical formation in the 0.65 gestation fetal sheep brain.
    Pediatric research, 2005, Volume: 58, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Asphyxia; Brain; Dehydroascorbic Acid; Electron Spin Resonance

2005
Pyruvate but not lactate prevents NADH-induced myoglobin oxidation.
    Free radical biology & medicine, 2005, Jun-01, Volume: 38, Issue:11

    Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Drug; Free Radicals; Horses; Hydrogen P

2005
Early postoperative function of the heart after coronary artery bypass grafting is not predicted by myocardial necrosis and glutathione-associated oxidative stress.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 359, Issue:1-2

    Topics: Aged; Coronary Artery Bypass; Female; Glutathione; Heart; Heart Arrest, Induced; Humans; Lactic Acid

2005
[Experimental study of protective effect of pueraria compound on the cerebral ischemic injury].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:7

    Topics: Animals; Antioxidants; Brain; Brain Ischemia; Drug Combinations; Gerbillinae; Glutathione Peroxidase

2005
Relationship between cerebral blood flow and oxygen metabolism, and extracellular glucose and lactate concentrations during middle cerebral artery occlusion and reperfusion: a microdialysis and positron emission tomography study in nonhuman primates.
    Journal of neurosurgery, 2005, Volume: 102, Issue:6

    Topics: Animals; Cerebrovascular Circulation; Disease Models, Animal; Extracellular Space; Glucose; Infarcti

2005
Gut luminal microdialysis of glycerol as a marker of intestinal ischemic injury and recovery.
    Critical care medicine, 2005, Volume: 33, Issue:10

    Topics: Adenosine Triphosphate; Animals; Biomarkers; Endothelium, Vascular; Glycerol; Intestinal Mucosa; Int

2005
Effect of nutritional status on oxidative stress in an ex vivo perfused rat liver.
    Anesthesiology, 2005, Volume: 103, Issue:5

    Topics: Animals; Bilirubin; Biomarkers; Blood Glucose; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Enz

2005
Effect of Polygala tenuifolia root extract on cerebral ischemia and reperfusion.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:1

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Brain; Brain Ischemia; Gerbillinae; Lactic Acid; Lipid P

2006
Effects of dopexamine in a rat model of supracoeliac aortic cross-clamping and declamping.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2006, Volume: 38, Issue:2

    Topics: Animals; Aorta, Abdominal; Blood Pressure; Carbon Dioxide; Celiac Artery; Dopamine; Lactic Acid; Mal

2006
D-lactate is not a reliable marker of gut ischemia-reperfusion in a rat model of supraceliac aortic clamping.
    Critical care medicine, 2006, Volume: 34, Issue:5

    Topics: Animals; Aortic Aneurysm; Inflammation; Intestinal Mucosa; Lactic Acid; Male; Models, Biological; Ra

2006
A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Adamantane; Adenosine Triphosphate; Animals; Anisoles; Glucose; Lactic Acid; Male; Propylamines; Rat

2006
Diagnostic and scientific dilemma: the ischemic bowel.
    Critical care medicine, 2006, Volume: 34, Issue:5

    Topics: Animals; Aorta; Lactic Acid; Models, Biological; Reperfusion Injury; Splanchnic Circulation; Stereoi

2006
Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts.
    Archives of physiology and biochemistry, 2006, Volume: 112, Issue:1

    Topics: Amiloride; Animals; Carnitine O-Palmitoyltransferase; Cell Survival; Enzyme Inhibitors; Fasting; Fat

2006
A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres.
    Experimental eye research, 2006, Volume: 83, Issue:4

    Topics: Animals; Cell Death; Delayed-Action Preparations; Drug Administration Schedule; Drug Evaluation, Pre

2006
[Effects of paeoniflorin on cerebral energy metabolism, nitric oxide and nitric oxide synthase after cerebral ischemia in mongoliagerbils].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:10

    Topics: Animals; Benzoates; Brain; Brain Ischemia; Bridged-Ring Compounds; Ca(2+) Mg(2+)-ATPase; Calcium-Tra

2006
Propofol attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in the rat.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:5

    Topics: Animals; Endothelin-1; Free Radical Scavengers; Intestinal Mucosa; Intestine, Small; Lactic Acid; Ma

2007
Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Capillaries; Cells, Cultured; Cerebrovascular Circulat

2008
[Testicular perfusion injury. Cytokines and cell adhesion molecules in humans].
    Der Urologe. Ausg. A, 2007, Volume: 46, Issue:9

    Topics: Anastomosis, Surgical; Cell Adhesion Molecules; Cryptorchidism; Cytokines; Epigastric Arteries; Huma

2007
Lactate and glycerol released to the intestinal lumen reflect mucosal injury and permeability changes caused by strangulation obstruction.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2007, Volume: 39, Issue:6

    Topics: Animals; Cell Membrane Permeability; Disease Models, Animal; Glycerol; Intestinal Mucosa; Intestinal

2007
Gut luminal lactate measured by microdialysis mirrors permeability of the intestinal mucosa after ischemia.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:2

    Topics: Animals; Glycerol; Hemodynamics; Intestinal Mucosa; Intestines; Ischemia; Lactic Acid; Male; Microdi

2008
Impact of female sex hormones on liver tissue lactic acidosis during ischemia.
    Transplantation, 2007, Sep-27, Volume: 84, Issue:6

    Topics: Acidosis, Lactic; Animals; Estradiol; Female; Gonadal Steroid Hormones; Hydrogen; Lactic Acid; Liver

2007
Effects of the TREM-1 pathway modulation during mesenteric ischemia-reperfusion in rats.
    Critical care medicine, 2008, Volume: 36, Issue:2

    Topics: Animals; Cytokines; Disease Models, Animal; Lactic Acid; Lipid Peroxidation; Male; Membrane Glycopro

2008
Orexigenic hormone ghrelin attenuates local and remote organ injury after intestinal ischemia-reperfusion.
    PloS one, 2008, Apr-23, Volume: 3, Issue:4

    Topics: Animals; Ghrelin; Inflammation; Injections, Intraventricular; Interleukin-6; Intestinal Mucosa; Inte

2008
Intermittent ischemia but not ischemic preconditioning is effective in restoring bile flow after ischemia reperfusion injury in the livers of aged rats.
    The Journal of surgical research, 2009, Volume: 152, Issue:1

    Topics: Aging; Animals; Bile; Bilirubin; Hepatocytes; Ischemic Preconditioning; Lactic Acid; Liver; Liver Fu

2009
Bradykinin accounts for improved postischemic function and decreased glutathione release of guinea pig heart treated with the angiotensin-converting enzyme inhibitor ramiprilat.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin Receptor Antagonists; Angiotensin-Convert

1994
Liposomes as in-vivo carriers for citicoline: effects on rat cerebral post-ischaemic reperfusion.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:12

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Blood-Brain Barrier; Brain Ischemia; Cerebral Cortex; C

1994
Effects of sepsis on recovery of the heart from 50 min ischemia.
    Shock (Augusta, Ga.), 1994, Volume: 1, Issue:6

    Topics: Adenosine Triphosphate; Alcoholism; Animals; Catalase; Escherichia coli; Lactates; Lactic Acid; Male

1994
Protective role in vivo of coenzyme Q10 during reperfusion of ischemic limbs.
    Molecular aspects of medicine, 1994, Volume: 15 Suppl

    Topics: Animals; Aorta, Abdominal; Coenzymes; Constriction; Creatine Kinase; Extremities; Ischemia; Isoenzym

1994
Nizofenone, a neuroprotective drug, suppresses glutamate release and lactate accumulation.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Analysis of Variance; Animals; Cell Death; Glutamic Acid; Hippocampus; Imidazoles; Injections, Intra

1994
Spinal cord ischemia and reperfusion metabolism: the effect of hypothermia.
    Journal of vascular surgery, 1994, Volume: 19, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Body Temperature; Combined Modality Therapy; Energy

1994
Ipsilateral and contralateral testicular biochemical acute changes after unilateral testicular torsion and detorsion.
    Urology, 1994, Volume: 44, Issue:3

    Topics: Animals; Hypoxanthine; Hypoxanthines; Hypoxia; Lactates; Lactic Acid; Lipid Peroxidation; Male; Rats

1994
Reperfusion injury after detorsion of unilateral testicular torsion.
    Urological research, 1993, Volume: 21, Issue:6

    Topics: Animals; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Male; Rats; Reperfusion Injury; Spermat

1993
Experimental evaluation of oxygen free radical scavengers in the prevention of reperfusion injury in skeletal muscle.
    The European journal of surgery = Acta chirurgica, 1994, Volume: 160, Issue:2

    Topics: Animals; Body Water; Female; Free Radical Scavengers; Free Radicals; Lactates; Lactic Acid; Male; Mu

1994
Substrate-induced changes in the lipid content of ischemic and reperfused myocardium. Its relation to hemodynamic recovery.
    Circulation research, 1993, Volume: 72, Issue:1

    Topics: Animals; Disease Models, Animal; Fatty Acids; Glucose; Glycerol; Heart; Lactates; Lactic Acid; Male;

1993
[Reperfusion shock after occlusion of the superior mesenteric artery and accumulation of leukocytes within the wall of the small intestine].
    Langenbecks Archiv fur Chirurgie, 1996, Volume: 381, Issue:2

    Topics: Animals; Blood Pressure; Intestine, Small; Ischemia; Lactates; Lactic Acid; Leukocyte Count; Leukocy

1996
[Behavior of the lactate level in occlusion and reperfusion of the right superior mesenteric artery. An animal experiment study].
    Langenbecks Archiv fur Chirurgie, 1996, Volume: 381, Issue:1

    Topics: Animals; Blood Pressure; Hydrogen-Ion Concentration; Intestinal Mucosa; Ischemia; Lactic Acid; Mesen

1996
Mapping of lactate and N-acetyl-L-aspartate predicts infarction during acute focal ischemia: in vivo 1H magnetic resonance spectroscopy in rats.
    Neurosurgery, 1996, Volume: 38, Issue:1

    Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Cerebral Infarction; Lactates; Lactic Acid; Magn

1996
Effects of platelet-activating factor antagonist E5880 on intrahepatic and systemic metabolic responses to transient hepatic inflow occlusion and reperfusion in the rabbit.
    World journal of surgery, 1996, Volume: 20, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Adenine Nucleotides; Ammonia; Analysis of Variance; Animals; Blood Gas

1996
High energy phosphates and direct calorimetry as predictive parameters for metabolic recovery of the rat liver following ischemia.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:8 Pt 1

    Topics: Adenine Nucleotides; Animals; Bile; Calorimetry; Energy Metabolism; In Vitro Techniques; Ischemia; L

1996
Ischemia/reperfusion injury in the rat colon.
    Inflammation, 1997, Volume: 21, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Aerobiosis; Aminosalicylic Acids; Anaerobiosis; Animals; Antioxidants;

1997
[The protective effects of dichloroacetate on cerebral ischemia after reperfusion of fed rats].
    Zhonghua yi xue za zhi, 1996, Volume: 76, Issue:7

    Topics: Animals; Brain Ischemia; Dichloroacetic Acid; Lactic Acid; Male; Neuroprotective Agents; Random Allo

1996
[O2 utilization during hyperthermic extremity perfusion with rhTNF alpha and melphalan].
    Langenbecks Archiv fur Chirurgie, 1997, Volume: 382, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Carbon Dioxide; Chemotherapy, Cancer, Re

1997
Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats.
    The Journal of surgical research, 1997, Volume: 73, Issue:1

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arteries; Energy Metabolism; Infusions, In

1997
Lipid peroxidation products and antioxidant capacity in portal venous and systemic arterial plasma during gradual intestinal ischemia and reperfusion in pigs.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1998, Volume: 30, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Female; Hemodynamics; Hydrogen-Ion Concentration; Int

1998
The effect of duration of cerebral ischemia on brain pyruvate dehydrogenase activity, energy metabolites, and blood flow during reperfusion in gerbil brain.
    Brain research, 1998, May-04, Volume: 792, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Energ

1998
Forearm semi-ischemic exercise test in pediatric patients.
    Journal of child neurology, 1998, Volume: 13, Issue:6

    Topics: Adolescent; Ammonia; Child; Exercise Test; Forearm; Humans; Lactic Acid; Metabolic Diseases; Reperfu

1998
Evidence that S-adenosyl-L-methionine diastereoisomers may reduce ischaemia-reperfusion injury by interacting with purinoceptors in isolated rat liver.
    British journal of pharmacology, 1998, Volume: 125, Issue:1

    Topics: Animals; Bile; Blood Flow Velocity; Enzyme Inhibitors; Glucose; Lactic Acid; Liver; Male; omega-N-Me

1998
Efficiency of trimetazidine in renal dysfunction secondary to cold ischemia-reperfusion injury: a proposed addition to University of Wisconsin solution.
    Cryobiology, 1998, Volume: 37, Issue:3

    Topics: Adenosine; Allopurinol; Animals; Citric Acid; Cold Temperature; Glomerular Filtration Rate; Glutathi

1998
Serum D-lactate levels as a predictor of intestinal ischemia-reperfusion injury.
    Pediatric surgery international, 1998, Volume: 14, Issue:1-2

    Topics: Animals; Biomarkers; Diuretics, Osmotic; Intestines; Lactic Acid; Mannitol; Rabbits; Reperfusion Inj

1998
Regional changes in cerebral extracellular glucose and lactate concentrations following severe cortical impact injury and secondary ischemia in rats.
    Journal of neurotrauma, 1999, Volume: 16, Issue:3

    Topics: Acidosis, Lactic; Animals; Blood Gas Analysis; Body Temperature; Brain Chemistry; Brain Injuries; Br

1999
Investigation of metabolism and perfusion in arterialized venous replantation: experimental study in rabbits.
    Annals of plastic surgery, 1999, Volume: 43, Issue:1

    Topics: Animals; Arteries; Blood Flow Velocity; Blood Glucose; Carbon Dioxide; Ear, External; Energy Metabol

1999
Influence of deflated and anaerobic conditions during cold storage on rat lungs.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:2

    Topics: Air; Anaerobiosis; Animals; Bronchoalveolar Lavage Fluid; Cryopreservation; Lactic Acid; Lung; Male;

1999
Lactate reduces amino acid release and fuels recovery of function in the ischemic brain.
    Neuroscience letters, 1999, Sep-17, Volume: 272, Issue:3

    Topics: Amino Acids; Animals; Brain Ischemia; Cerebral Cortex; Electroencephalography; Injections; Lactic Ac

1999
Intestinal luminal microdialysis: a new approach to assess gut mucosal ischemia.
    Anesthesiology, 1999, Volume: 91, Issue:6

    Topics: Animals; Carbon Dioxide; Female; Intestinal Mucosa; Ischemia; Lactic Acid; Microdialysis; Regional B

1999
Implementation of the microdialysis method in the hamster dorsal skinfold chamber.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1999, Volume: 199, Issue:3

    Topics: Animals; Brain Chemistry; Cricetinae; Diffusion Chambers, Culture; Lactic Acid; Male; Mesocricetus;

1999
[Parameters of energy metabolism in patients after vascular reconstructive surgical procedures].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:8

    Topics: Acid-Base Equilibrium; Adult; Antioxidants; Energy Metabolism; Female; Humans; Ischemia; Lactic Acid

1999
[Relationship between plasma D(-)-lactate levels and acute intestinal injury in rats following ischemia-reperfusion].
    Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, 1998, Volume: 14, Issue:4

    Topics: Animals; Biomarkers; Intestinal Mucosa; Intestines; Lactic Acid; Male; Random Allocation; Rats; Rats

1998
A new method of long-term preventive cardioprotection using Lactobacillus.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5

    Topics: Adenosine Triphosphate; Animals; Body Temperature; Cardiovascular Agents; Catalase; Coronary Circula

2000
Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studies with DL-threo-beta-benzyloxyaspartate.
    Brain research, 2000, Jun-16, Volume: 868, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain I

2000
Effects of naloxone on lactate, pyruvate metabolism and antioxidant enzyme activity in rat cerebral ischemia/reperfusion.
    Neuroscience letters, 2000, Jun-23, Volume: 287, Issue:2

    Topics: Animals; Antioxidants; Brain; Catalase; Energy Metabolism; Free Radicals; Glutathione Peroxidase; Is

2000
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
    Neuroscience letters, 2000, Jul-07, Volume: 288, Issue:1

    Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid

2000
Hypertonic/hyperoncotic resuscitation after intestinal superior mesenteric artery occlusion: early effects on circulation and intestinal reperfusion.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Cardiac Output; Constriction; Fluid Therapy; H

2000
Posthypoxic reoxygenation-induced neurotoxicity prevented by free radical scavenger and NMDA/non-NMDA antagonist in tandem as revealed by dynamic changes in glucose metabolism with positron autoradiography.
    Experimental neurology, 2000, Volume: 164, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Autoradiography; Cell Hypoxia; Cell Survival; Colorin

2000
Cardioplegic strategies for calcium control: low Ca(2+), high Mg(2+), citrate, or Na(+)/H(+) exchange inhibitor HOE-642.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cardioplegic Solutions; Citric Acid

2000
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Corte

2000
Reduced production of lactate during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats.
    Neuroscience letters, 2000, Dec-22, Volume: 296, Issue:2-3

    Topics: Animals; Astrocytes; Carrier Proteins; Cell Death; Cells, Cultured; Fetus; Hypoxia, Brain; L-Lactate

2000
Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:6

    Topics: Animals; Calcium Channel Blockers; Carnitine O-Palmitoyltransferase; Coronary Circulation; Enzyme In

2000
The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex.
    Neurosurgery, 2001, Volume: 48, Issue:2

    Topics: Acute Disease; Amino Acids; Animals; Blood Glucose; Brain Ischemia; Cerebral Cortex; Chronic Disease

2001
Noninvasive monitoring of citrate, acetate, lactate, and renal medullary osmolyte excretion in urine as biomarkers of exposure to ischemic reperfusion injury.
    Cryobiology, 2000, Volume: 41, Issue:4

    Topics: Acetic Acid; Acetylglucosaminidase; Acute Kidney Injury; Adenosine; Allopurinol; Animals; Biomarkers

2000
Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzofurans; Brain; Brain Ischemia; Lactic Acid; Male

2000
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.
    Acta physiologica Scandinavica, 2001, Volume: 171, Issue:2

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal

2001
Further studies on the effects of topical lactate on amino acid efflux from the ischemic rat cortex.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Administration, Topical; Amino Acids; Animals; Brain Ischemia; Cardiovascular Physiological Phenomen

2001
Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation-reperfusion period after acute transient global hypoxia-ischemia in the newborn piglet.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Gas Analysis; Blood

2001
Middle cerebral artery occlusion and reperfusion in primates monitored by microdialysis and sequential positron emission tomography.
    Stroke, 2001, Volume: 32, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Glutamic Acid; Hypoxanthine; Infarction

2001
Mesenteric and renal oxygen transport during hemorrhage and reperfusion: evaluation of optimal goals for resuscitation.
    The Journal of trauma, 2001, Volume: 51, Issue:2

    Topics: Acid-Base Equilibrium; Animals; Female; Fluid Therapy; Gastric Acidity Determination; Hemodynamics;

2001
Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model.
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 71, Issue:4

    Topics: Animals; Brain Damage, Chronic; Extracellular Space; Glutamic Acid; Glycerol; Infarction, Middle Cer

2001
Effects of ovariectomy and estrogen on ischemia-reperfusion injury in hindlimbs of female rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:4

    Topics: Animals; Antigens, CD; Calpain; Creatine Kinase; Estrogens; Female; Glycogen; Hindlimb; Insulin-Like

2001
Effect of hyperbaric oxygen on striatal metabolites: a microdialysis study in awake freely moving rats after MCA occlusion.
    Brain research, 2001, Oct-19, Volume: 916, Issue:1-2

    Topics: Animals; Brain Ischemia; Corpus Striatum; Energy Metabolism; Extracellular Space; Glucose; Glutamic

2001
Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.
    Journal of neuroscience research, 2001, Dec-01, Volume: 66, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Glucose; Brain Ischemia; Corticostero

2001
Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects.
    Circulation, 2001, Dec-18, Volume: 104, Issue:25

    Topics: Anaphylatoxins; Animals; Blood Gas Analysis; Cardiac Output; Complement C1 Inactivator Proteins; Cor

2001
Changes in the contents of glycogen and lactate in the brain and blood during hypoxic preconditioning.
    Sheng li xue bao : [Acta physiologica Sinica], 2001, Volume: 53, Issue:4

    Topics: Animals; Brain; Diencephalon; Female; Glycogen; Hypoxia, Brain; Ischemic Preconditioning; Lactic Aci

2001
Intestinal energy metabolism after ischemia-reperfusion: Effects of moderate hypothermia and perfluorocarbons.
    Journal of pediatric surgery, 2002, Volume: 37, Issue:5

    Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Fluorocarbons; Hypothermia, Induced; Ileum; Inte

2002
Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique.
    Life sciences, 2002, Jul-05, Volume: 71, Issue:7

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Energy Metabolism; Gerbillinae; Gluco

2002
Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:6

    Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Cations; Dichloroacetic Acid; Disease Models, Anima

1992
Hypothermia relieves oxidative stress in reperfused skeletal muscle following partial ischemia.
    The Journal of surgical research, 1992, Volume: 53, Issue:4

    Topics: Adenosine Triphosphate; Animals; Free Radicals; Hypothermia, Induced; Lactates; Lactic Acid; Lipid P

1992
Prolonged adenine nucleotide resynthesis and reperfusion injury in postischemic skeletal muscle.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 2

    Topics: Adenine Nucleotides; Animals; Creatine Kinase; Dogs; Ischemia; Lactates; Lactic Acid; Muscles; Necro

1992
Effects of acute lower limb ischemia on femoral venous efflux.
    Angiology, 1990, Volume: 41, Issue:6

    Topics: Animals; Creatine Kinase; Femoral Vein; Humans; Hydrogen-Ion Concentration; Ischemia; L-Lactate Dehy

1990
Intraischemic metabolic effects of different disaccharides on protected canine kidneys.
    Urological research, 1989, Volume: 17, Issue:6

    Topics: Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Glucose; Hypertonic Solutions; Kidney; Lac

1989
Hyperoxia during reperfusion is a factor in reperfusion injury.
    Free radical biology & medicine, 1989, Volume: 6, Issue:1

    Topics: Free Radicals; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Oxygen; Reperfusion Injury; Supero

1989