lactic acid has been researched along with Reflex Sympathetic Dystrophy in 2 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Reflex Sympathetic Dystrophy: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the CPIP acute phase, we observed mechanical and cold allodynia; increased levels of tumor necrosis factor-α (hind paw), ischemia-modified albumin (IMA) (serum), protein carbonyl (hind paw and spinal cord), lactate (serum), and 4-hydroxy-2-nonenal (4-HNE, hind paw and spinal cord); and higher myeloperoxidase (MPO) and N-acetyl-β-D-glucosaminidase (NAGase) activities (hind paw)." | 3.83 | Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms. ( Bochi, GV; da Silva, MA; de Prá, SD; Ferreira, J; Klafke, JZ; Moresco, RN; Rigo, FK; Rossato, MF; Trevisan, G; Walker, CI, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klafke, JZ | 1 |
| da Silva, MA | 1 |
| Rossato, MF | 1 |
| de Prá, SD | 1 |
| Rigo, FK | 1 |
| Walker, CI | 1 |
| Bochi, GV | 1 |
| Moresco, RN | 1 |
| Ferreira, J | 1 |
| Trevisan, G | 1 |
| Birklein, F | 1 |
| Weber, M | 1 |
| Neundörfer, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Near-infrared Spectroscopic Measurement of Tissue Oxygen Saturation and the Vascular Occlusion Test in Complex Regional Pain Syndrome[NCT01586377] | 20 participants (Actual) | Observational | 2011-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for lactic acid and Reflex Sympathetic Dystrophy
| Article | Year |
|---|---|
Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms.
Topics: Acetylglucosaminidase; Acute Pain; Aldehydes; Animals; Chronic Pain; Cold Temperature; Hindlimb; Hyp | 2016 |
Increased skin lactate in complex regional pain syndrome: evidence for tissue hypoxia?
Topics: Adult; Female; Humans; Hypoxia; Lactic Acid; Male; Microdialysis; Middle Aged; Reflex Sympathetic Dy | 2000 |