lactic acid has been researched along with Pulmonary Disease, Chronic Obstructive in 51 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, due to its rare association with lactic acidosis, its safety in COPD is uncertain." | 3.81 | Safety of metformin in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus. ( Archer, JR; Baker, EH; Hitchings, AW; Srivastava, SA, 2015) |
| "Fifteen moderate to severe COPD patients were randomized and evaluated with and without (Non-EPAP) a 5 cmH2O EPAP device." | 2.87 | Influence of expiratory positive airway pressure on cardiac autonomic modulation at rest and in submaximal exercise in COPD patients. ( da L Goulart, C; da Silva, ALG; Mansour, KMK; San Martin, EA; Schneiders, PB, 2018) |
| "At both 6- and 24-hour measurements, the fluid volume was lower and norepinephrine dosage was higher in the control group than in the study group (P < ." | 2.84 | Global end-diastolic volume index vs CVP goal-directed fluid resuscitation for COPD patients with septic shock: a randomized controlled trial. ( Chen, Q; Lin, H; Shao, J; Wang, D; Yu, J; Zheng, R, 2017) |
| "Chronic obstructive pulmonary disease (COPD) is pulmonary emphysema characterized by blockage in the airflow resulting in the long-term breathing problem, hence a major cause of mortality worldwide." | 2.82 | Targeting COPD with PLGA-Based Nanoparticles: Current Status and Prospects. ( Bisen, M; Jyoti, A; Kaushik, S; Mishra, N; Misra, A; Saxena, J; Siddiqui, AJ; Singh, A; Srivastava, VK, 2022) |
| "Oxygen administration for COPD patients in Bogotá significantly increased ET by decreased respiratory load, improved cardiovascular performance and oxygen transport." | 2.79 | Exercise endurance in chronic obstructive pulmonary disease patients at an altitude of 2640 meters breathing air and oxygen (FIO2 28% and 35%): a randomized crossover trial. ( Barrero, M; Casas, A; González-García, M; Jaramillo, C; Maldonado, D, 2014) |
| "[Background] In patients with chronic obstructive pulmonary disease (COPD), early lactic acidosis during exercise should be considered as playing a role in the limitation of exercise tolerance." | 2.75 | Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in healthy subjects and patients with COPD. ( Abe, T; Fujiwara, H; Ichiwata, T; Kikuchi, K; Koyama, K; Kuwahira, I; Nagai, A; Nagao, K; Sasao, G, 2010) |
| "Eighteen subjects with COPD performed maximal cycle exercise after an intravenous infusion of DCA (50 mg/kg body mass) or saline (control)." | 2.73 | Dichloroacetate enhances performance and reduces blood lactate during maximal cycle exercise in chronic obstructive pulmonary disease. ( Bankart, J; Calvert, LD; Greenhaff, PL; Morgan, MD; Shelley, R; Singh, SJ; Steiner, MC, 2008) |
| "Sixteen COPD patients (mean FEV1 33+/-13% predicted) underwent a 6-min walking test and performed stair-climbing (44 steps) in a randomized, cross-over design." | 2.73 | Exercise in severe COPD: is walking different from stair-climbing? ( Dreher, M; Kabitz, HJ; Prettin, S; Sonntag, F; Walterspacher, S; Windisch, W, 2008) |
| "In seven patients with COPD (FEV(1) = 33 +/- 14% of predicted), measurements of [lactate](a) were made each minute during progressive inspiratory threshold loading to voluntary exhaustion." | 2.72 | Anaerobic metabolism of inspiratory muscles in COPD. ( Eastwood, PR; Hillman, DR; Jenkins, SC; Sturdy, GA; Van Der Touw, TJ, 2006) |
| "Forty-three COPD patients (II=16, ID=12, DD=15) underwent right heart catheterization, and then performed an exercise test with room air or oxygen." | 2.71 | Influence of oxygen administration on pulmonary haemodynamics and tissue oxygenation during exercise in COPD patients with different ACE genotypes. ( Hirata, K; Kanazawa, H; Yoshikawa, J, 2003) |
| "Pulmonary rehabilitation in active COPD patients may normalize the electrical activity of skeletal muscles during incremental dynamic exercise." | 2.71 | Endurance training improves skeletal muscle electrical activity in active COPD patients. ( Gosselin, N; Lambert, K; Martin, A; Poulain, M; Préfaut, C; Varray, A, 2003) |
| "We hypothesized that patients with chronic obstructive pulmonary disease developing contractile fatigue of the quadriceps during cycle exercise may have characteristic metabolic and muscle features that could increase their susceptibility to fatigue, thus differentiating them from those who do not develop fatigue." | 2.71 | Contractile fatigue, muscle morphometry, and blood lactate in chronic obstructive pulmonary disease. ( Côté, CH; Couillard, A; Jobin, J; LeBlanc, P; Mador, MJ; Maltais, F; Michaud, A; Saey, D, 2005) |
| "Twelve subjects with COPD were evaluated in this cross-sectional study." | 1.48 | Critical Velocity Determined by a Non-Exhaustive Method in Subjects With COPD. ( Campos, EZ; Christofaro, DGD; de Alencar Silva, BS; de Lima, FF; Freire, APCF; Kalva-Filho, CA; Leite, MR; Ramos, D; Ramos, EMC; Uzeloto, JS, 2018) |
| "Our IPO and non-IPO patients with COPD had similar cardiovascular performance at rest and at peak exercise, indicating that IPO variables are non-specific for cardiovascular function in these patients." | 1.42 | Cardiovascular and respiratory dysfunction in chronic obstructive pulmonary disease complicated by impaired peripheral oxygenation. ( Chuang, ML; Huang, SF; Su, CH, 2015) |
| "Nine COPD patients [age, 60." | 1.39 | Sinusoidal high-intensity exercise does not elicit ventilatory limitation in chronic obstructive pulmonary disease. ( Casaburi, R; Kiledjian, R; Ma, S; Porszasz, J; Rambod, M; Rossiter, HB; van der Vaart, H, 2013) |
| "At baseline, COPD patients showed greater muscle oxidative stress and superoxide dismutase activity and circulating inflammatory cytokines than controls." | 1.38 | Muscle and blood redox status after exercise training in severe COPD patients. ( Barreiro, E; Cascante, M; Falciani, F; Gea, J; Kalko, S; Perez-Olabarría, M; Puig-Vilanova, E; Roca, J; Rodriguez, DA, 2012) |
| "However, not all COPD patients benefit from PR to the same extent." | 1.38 | A better response in exercise capacity after pulmonary rehabilitation in more severe COPD patients. ( Altenburg, WA; de Greef, MH; ten Hacken, NH; Wempe, JB, 2012) |
| "Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with comorbidities and multidrug therapy is complicated by mixed acid-base, hydro-electrolyte and lactate disorders." | 1.38 | Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation. ( Conti, V; Di Nicola, M; Di Stefano, F; Paone, G; Petroianni, A; Ricci, A; Terzano, C, 2012) |
| "We measured, in 12 patients with COPD and 10 control subjects, resting and post-cycling exercise quadriceps levels of 1) energy substrates and end products of glycolysis (glycogen, glucose, pyruvate, and lactate) and intermediate markers of glycolysis (glucose-6-phosphate, glucose-1-phosphate, fructose-6-phosphate) and 2) the activity of key enzymes involved in the regulation of glycolysis (phosphofructokinase, lactate dehydrogenase)." | 1.37 | Quadriceps metabolism during constant workrate cycling exercise in chronic obstructive pulmonary disease. ( Bombardier, E; Côté, CH; Debigaré, R; Gagnon, P; Lemire, BB; Maltais, F; Saey, D; Tupling, AR, 2011) |
| "Eleven patients with COPD (67 ± 8 years; forced expiratory volume in 1 s (FEV1) 45 ± 8%ref) and 10 healthy controls (66 ± 4 years; FEV1 90 ± 7% ref) cycled 45 min above LT (65% peak oxygen uptake (V′o2peak) and another 7 patients (65 ± 6 years; FEV1 50 ± 4%ref) and 7 controls (56 ± 9 years; FEV1 92 ± 6% ref) cycled 45 min below their LT (50% V′o2peak)." | 1.37 | Effects of exercise on mitochondrial DNA content in skeletal muscle of patients with COPD. ( Agustí, A; Camaño, S; Cuervo, M; Fuentes, M; Lázaro, A; Navarro, BO; Puente-Maestu, L; Tejedor, A, 2011) |
| "Patients with COPD exhibit greater oxyhemoglobin desaturation during walking than with cycling." | 1.37 | Mechanism of greater oxygen desaturation during walking compared with cycling in patients with COPD. ( Baird, JC; Gifford, AH; Machala, S; Mahler, DA; Ward, J; Waterman, LA, 2011) |
| "Twenty-nine subjects with stable COPD [mean(SD) age 68(7)years, FEV(1) 50(19)% predicted] performed maximal cardiopulmonary exercise tests on a cycle ergometer and treadmill." | 1.36 | Plasma ammonia response to incremental cycling and walking tests in COPD. ( Calvert, LD; Morgan, MD; Singh, SJ; Steiner, MC, 2010) |
| "Patients with chronic obstructive pulmonary disease (COPD) may suffer dyspnea when performing unsupported arm exercises (UAE)." | 1.36 | Lactic acid levels in patients with chronic obstructive pulmonary disease accomplishing unsupported arm exercises. ( Castro, AA; de Souza, GF; Jardim, JR; Silva, CR; Velloso, M, 2010) |
| "Glycogen storage was not affected by the disease (289 +/- 20 vs." | 1.35 | Altered metabolic and transporter characteristics of vastus lateralis in chronic obstructive pulmonary disease. ( Burnett, ME; D'Arsigny, CL; Green, HJ; O'Donnell, DE; Ouyang, J; Webb, KA, 2008) |
| "During 2-KE the controls and COPD patients achieved 85% (4%) and 67% (5%) (P=0." | 1.35 | Higher skeletal muscular metabolic reserve capacity in COPD patients than healthy subjects. ( Christensen, CC; Edvardsen, A; Hallén, J; Rud, B; Ryg, M; Skumlien, S, 2009) |
| "Systemic effects of COPD include skeletal muscle dysfunction; the lactate threshold (LT) is an index of such dysfunction." | 1.35 | Arterial blood lactate is a useful guide to when rehabilitation should be instigated in COPD. ( Hino, M; Kudoh, S; Mizuno, K; Morikawa, T; Takeuchi, K; Tanaka, Y, 2008) |
| "Shock was more frequently present in the low [BE] group (46% versus 24%, P = 0." | 1.35 | Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches. ( Dubin, A; Kutscherauer, DO; Masevicius, FD; Pein, MC; Tuhay, G, 2008) |
| "Compared with a control group, COPD patients had lower MVCs, an attenuated decrease in MF during exercise, lower resting level of GSH, no posthandgrip TBARS increase and no GSH consumption." | 1.32 | Influence of chronic hypoxemia on peripheral muscle function and oxidative stress in humans. ( Barbier, D; Faucher, M; Hug, F; Jammes, Y; Steinberg, JG, 2004) |
| "Patients with chronic obstructive pulmonary disease (COPD) are characterised by decreased exercise tolerance, and, more variably, exercise induced hypoxaemia (EIH)." | 1.32 | Effect of exercise mode on oxygen uptake and blood gases in COPD patients. ( Christensen, CC; Edvardsen, A; Ryg, MS; Skjønsberg, OH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 17 (33.33) | 29.6817 |
| 2010's | 29 (56.86) | 24.3611 |
| 2020's | 5 (9.80) | 2.80 |
| Authors | Studies |
|---|---|
| Saxena, J | 1 |
| Bisen, M | 1 |
| Misra, A | 1 |
| Srivastava, VK | 1 |
| Kaushik, S | 1 |
| Siddiqui, AJ | 1 |
| Mishra, N | 1 |
| Singh, A | 1 |
| Jyoti, A | 1 |
| Iamonti, VC | 1 |
| Souza, GF | 1 |
| Castro, AAM | 1 |
| Porto, EF | 1 |
| Cruz, LGB | 1 |
| Colucci, E | 1 |
| Colucci, M | 1 |
| Sarmento, A | 1 |
| Nascimento, OA | 1 |
| Jardim, JR | 2 |
| Guo, X | 1 |
| Zuo, X | 1 |
| Zhou, Z | 1 |
| Gu, Y | 1 |
| Zheng, H | 2 |
| Wang, X | 1 |
| Wang, G | 1 |
| Xu, C | 1 |
| Wang, F | 1 |
| Ogura, A | 1 |
| Tsurumi, A | 1 |
| Que, YA | 1 |
| Almpani, M | 1 |
| Tompkins, RG | 1 |
| Ryan, CM | 1 |
| Rahme, LG | 1 |
| Bhavani, SV | 1 |
| Huang, ES | 1 |
| Verhoef, PA | 1 |
| Churpek, MM | 1 |
| Neunhäuserer, D | 1 |
| Reich, B | 1 |
| Mayr, B | 1 |
| Kaiser, B | 1 |
| Lamprecht, B | 1 |
| Niederseer, D | 1 |
| Ermolao, A | 1 |
| Studnicka, M | 1 |
| Niebauer, J | 1 |
| Daniels, CE | 1 |
| Litin, SC | 1 |
| Bundrick, JB | 1 |
| Durmuş, U | 1 |
| Doğan, NÖ | 1 |
| Pekdemir, M | 1 |
| Yılmaz, S | 1 |
| Yaka, E | 1 |
| Karadaş, A | 1 |
| Güney Pınar, S | 1 |
| Leite, MR | 1 |
| Uzeloto, JS | 1 |
| de Alencar Silva, BS | 1 |
| Freire, APCF | 1 |
| de Lima, FF | 1 |
| Campos, EZ | 1 |
| Christofaro, DGD | 1 |
| Kalva-Filho, CA | 1 |
| Ramos, D | 1 |
| Ramos, EMC | 1 |
| Jeong, HS | 1 |
| Lee, TH | 1 |
| Bang, CH | 1 |
| Kim, JH | 1 |
| Hong, SJ | 1 |
| da L Goulart, C | 1 |
| San Martin, EA | 1 |
| Mansour, KMK | 1 |
| Schneiders, PB | 1 |
| da Silva, ALG | 1 |
| Zante, B | 1 |
| Reichenspurner, H | 1 |
| Kubik, M | 1 |
| Kluge, S | 1 |
| Schefold, JC | 1 |
| Pfortmueller, CA | 1 |
| Maldonado, D | 1 |
| González-García, M | 1 |
| Barrero, M | 1 |
| Jaramillo, C | 1 |
| Casas, A | 1 |
| Aquilani, R | 1 |
| D'Antona, G | 1 |
| Baiardi, P | 1 |
| Gambino, A | 1 |
| Iadarola, P | 1 |
| Viglio, S | 1 |
| Pasini, E | 1 |
| Verri, M | 1 |
| Barbieri, A | 1 |
| Boschi, F | 1 |
| Chuang, ML | 1 |
| Huang, SF | 1 |
| Su, CH | 1 |
| Remels, AH | 1 |
| Gosker, HR | 1 |
| Verhees, KJ | 1 |
| Langen, RC | 1 |
| Schols, AM | 1 |
| Hitchings, AW | 1 |
| Archer, JR | 1 |
| Srivastava, SA | 1 |
| Baker, EH | 1 |
| Greguš, M | 1 |
| Foret, F | 1 |
| Kindlová, D | 1 |
| Pokojová, E | 1 |
| Plutinský, M | 1 |
| Doubková, M | 1 |
| Merta, Z | 1 |
| Binková, I | 1 |
| Skřičková, J | 1 |
| Kubáň, P | 2 |
| Vij, N | 1 |
| Min, T | 1 |
| Bodas, M | 1 |
| Gorde, A | 1 |
| Roy, I | 1 |
| Yu, J | 1 |
| Zheng, R | 1 |
| Lin, H | 1 |
| Chen, Q | 1 |
| Shao, J | 1 |
| Wang, D | 1 |
| Green, HJ | 1 |
| Burnett, ME | 1 |
| D'Arsigny, CL | 1 |
| O'Donnell, DE | 1 |
| Ouyang, J | 1 |
| Webb, KA | 1 |
| Ba, A | 1 |
| Delliaux, S | 1 |
| Bregeon, F | 1 |
| Levy, S | 1 |
| Jammes, Y | 2 |
| Rud, B | 1 |
| Christensen, CC | 2 |
| Ryg, M | 1 |
| Edvardsen, A | 2 |
| Skumlien, S | 1 |
| Hallén, J | 1 |
| Calvert, LD | 2 |
| Steiner, MC | 2 |
| Morgan, MD | 2 |
| Singh, SJ | 2 |
| Rondelli, RR | 1 |
| Dal Corso, S | 1 |
| Simões, A | 1 |
| Malaguti, C | 1 |
| Ichiwata, T | 1 |
| Sasao, G | 1 |
| Abe, T | 1 |
| Kikuchi, K | 1 |
| Koyama, K | 1 |
| Fujiwara, H | 1 |
| Nagai, A | 1 |
| Kuwahira, I | 1 |
| Nagao, K | 1 |
| de Souza, GF | 1 |
| Castro, AA | 1 |
| Velloso, M | 1 |
| Silva, CR | 1 |
| Saey, D | 2 |
| Lemire, BB | 1 |
| Gagnon, P | 1 |
| Bombardier, E | 1 |
| Tupling, AR | 1 |
| Debigaré, R | 1 |
| Côté, CH | 2 |
| Maltais, F | 2 |
| Puente-Maestu, L | 1 |
| Lázaro, A | 1 |
| Tejedor, A | 1 |
| Camaño, S | 1 |
| Fuentes, M | 1 |
| Cuervo, M | 1 |
| Navarro, BO | 1 |
| Agustí, A | 1 |
| Mahler, DA | 1 |
| Gifford, AH | 1 |
| Waterman, LA | 1 |
| Ward, J | 1 |
| Machala, S | 1 |
| Baird, JC | 1 |
| Yoo, NY | 1 |
| Youn, YS | 1 |
| Oh, NM | 1 |
| Oh, KT | 1 |
| Lee, DK | 1 |
| Cha, KH | 1 |
| Oh, YT | 1 |
| Lee, ES | 1 |
| Rodriguez, DA | 1 |
| Kalko, S | 1 |
| Puig-Vilanova, E | 1 |
| Perez-Olabarría, M | 1 |
| Falciani, F | 1 |
| Gea, J | 1 |
| Cascante, M | 1 |
| Barreiro, E | 1 |
| Roca, J | 1 |
| Ostroukhova, M | 1 |
| Goplen, N | 1 |
| Karim, MZ | 1 |
| Michalec, L | 1 |
| Guo, L | 1 |
| Liang, Q | 1 |
| Alam, R | 1 |
| Altenburg, WA | 1 |
| de Greef, MH | 1 |
| ten Hacken, NH | 1 |
| Wempe, JB | 1 |
| Terzano, C | 1 |
| Di Stefano, F | 1 |
| Conti, V | 1 |
| Di Nicola, M | 1 |
| Paone, G | 1 |
| Petroianni, A | 1 |
| Ricci, A | 1 |
| Kobrin, EG | 1 |
| Kaljurand, M | 1 |
| van Noort, JM | 1 |
| Bsibsi, M | 1 |
| Nacken, PJ | 1 |
| Gerritsen, WH | 1 |
| Amor, S | 1 |
| Holtman, IR | 1 |
| Boddeke, E | 1 |
| van Ark, I | 1 |
| Leusink-Muis, T | 1 |
| Folkerts, G | 1 |
| Hennink, WE | 1 |
| Amidi, M | 1 |
| Porszasz, J | 1 |
| Rambod, M | 1 |
| van der Vaart, H | 1 |
| Rossiter, HB | 1 |
| Ma, S | 1 |
| Kiledjian, R | 1 |
| Casaburi, R | 1 |
| Kanazawa, H | 1 |
| Hirata, K | 1 |
| Yoshikawa, J | 1 |
| Gosselin, N | 1 |
| Lambert, K | 1 |
| Poulain, M | 1 |
| Martin, A | 1 |
| Préfaut, C | 1 |
| Varray, A | 1 |
| Faucher, M | 1 |
| Steinberg, JG | 1 |
| Barbier, D | 1 |
| Hug, F | 1 |
| Ryg, MS | 1 |
| Skjønsberg, OH | 1 |
| Sabapathy, S | 1 |
| Kingsley, RA | 1 |
| Schneider, DA | 1 |
| Adams, L | 1 |
| Morris, NR | 1 |
| Michaud, A | 1 |
| Couillard, A | 1 |
| Mador, MJ | 1 |
| LeBlanc, P | 1 |
| Jobin, J | 1 |
| Richard, C | 1 |
| Teboul, JL | 1 |
| Eastwood, PR | 1 |
| Van Der Touw, TJ | 1 |
| Sturdy, GA | 1 |
| Jenkins, SC | 1 |
| Hillman, DR | 1 |
| Shelley, R | 1 |
| Greenhaff, PL | 1 |
| Bankart, J | 1 |
| Dreher, M | 1 |
| Walterspacher, S | 1 |
| Sonntag, F | 1 |
| Prettin, S | 1 |
| Kabitz, HJ | 1 |
| Windisch, W | 1 |
| Tanaka, Y | 1 |
| Hino, M | 1 |
| Morikawa, T | 1 |
| Takeuchi, K | 1 |
| Mizuno, K | 1 |
| Kudoh, S | 1 |
| Tuhay, G | 1 |
| Pein, MC | 1 |
| Masevicius, FD | 1 |
| Kutscherauer, DO | 1 |
| Dubin, A | 1 |
| Wadell, K | 1 |
| Henriksson-Larsén, K | 1 |
| Lundgren, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Effects of Low Level Laser Therapy in Muscle Function of Patients With Heart Failure.[NCT02508792] | 20 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | |||
| Effect of the VitaBreath Device on Chest Wall Dynamic Hyperinflation and Respiratory Muscle Activation During Recovery From Exercise in Patients With Chronic Obstructive Pulmonary Disease[NCT03848819] | 14 participants (Actual) | Interventional | 2019-07-01 | Completed | |||
| Comparison of Clinical and Physiological Response Among Three Modalities of Exercise Training in COPD With Chronic Respiratory Failure (CRF)[NCT04201548] | 60 participants (Anticipated) | Interventional | 2019-08-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for lactic acid and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Targeting COPD with PLGA-Based Nanoparticles: Current Status and Prospects.
Topics: Antioxidants; Drug Carriers; Glycols; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylac | 2022 |
PLGA-Based Micro/Nanoparticles: An Overview of Their Applications in Respiratory Diseases.
Topics: Asthma; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polygl | 2023 |
Essential amino acids and exercise tolerance in elderly muscle-depleted subjects with chronic diseases: a rehabilitation without rehabilitation?
Topics: Aged; Aged, 80 and over; Chronic Disease; Exercise Therapy; Exercise Tolerance; Female; Heart Failur | 2014 |
Methods for the assessment of peripheral muscle fatigue and its energy and metabolic determinants in COPD.
Topics: Ammonia; Biopsy; Electromyography; Exercise; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; M | 2009 |
12 trials available for lactic acid and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Impact of exercise training and supplemental oxygen on submaximal exercise performance in patients with COPD.
Topics: Activities of Daily Living; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Exercise | 2021 |
Influence of expiratory positive airway pressure on cardiac autonomic modulation at rest and in submaximal exercise in COPD patients.
Topics: Autonomic Nervous System; Cross-Over Studies; Cross-Sectional Studies; Forced Expiratory Volume; Hea | 2018 |
Exercise endurance in chronic obstructive pulmonary disease patients at an altitude of 2640 meters breathing air and oxygen (FIO2 28% and 35%): a randomized crossover trial.
Topics: Aged; Air; Altitude; Colombia; Cross-Over Studies; Exercise Test; Exercise Tolerance; Female; Heart | 2014 |
Global end-diastolic volume index vs CVP goal-directed fluid resuscitation for COPD patients with septic shock: a randomized controlled trial.
Topics: Aged; Cardiac Output; Central Venous Pressure; Clinical Protocols; Diastole; Female; Fluid Therapy; | 2017 |
Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in healthy subjects and patients with COPD.
Topics: Adult; Aged; Exercise Test; Health; Humans; Lactic Acid; Middle Aged; Muscle, Skeletal; Oxidation-Re | 2010 |
Influence of oxygen administration on pulmonary haemodynamics and tissue oxygenation during exercise in COPD patients with different ACE genotypes.
Topics: Administration, Inhalation; Aged; Exercise Test; Humans; Lactic Acid; Lung; Male; Middle Aged; Oxyge | 2003 |
Endurance training improves skeletal muscle electrical activity in active COPD patients.
Topics: Anaerobic Threshold; Blood Gas Analysis; Electromyography; Electrophysiology; Exercise Test; Female; | 2003 |
Contractile fatigue, muscle morphometry, and blood lactate in chronic obstructive pulmonary disease.
Topics: Aged; Capillaries; Citrate (si)-Synthase; Exercise; Humans; L-Lactate Dehydrogenase; Lactic Acid; Ma | 2005 |
Anaerobic metabolism of inspiratory muscles in COPD.
Topics: Anaerobic Threshold; Breathing Exercises; Exercise Therapy; Female; Humans; Inhalation; Lactic Acid; | 2006 |
Dichloroacetate enhances performance and reduces blood lactate during maximal cycle exercise in chronic obstructive pulmonary disease.
Topics: Aged; Aged, 80 and over; Ammonia; Cross-Over Studies; Dichloroacetic Acid; Double-Blind Method; Enzy | 2008 |
Exercise in severe COPD: is walking different from stair-climbing?
Topics: Aged; Carbon Dioxide; Cross-Over Studies; Dyspnea; Exercise; Exercise Test; Female; Forced Expirator | 2008 |
Physical training with and without oxygen in patients with chronic obstructive pulmonary disease and exercise-induced hypoxaemia.
Topics: Aged; Carbon Dioxide; Exercise; Exercise Test; Exercise Therapy; Female; Humans; Hypoxia; Lactic Aci | 2001 |
35 other studies available for lactic acid and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Upper Limb Anaerobic Metabolism Capacity is Reduced in Mild and Moderate COPD Patients.
Topics: Anaerobiosis; Exercise Test; Humans; Lactic Acid; Male; Pulmonary Disease, Chronic Obstructive; Uppe | 2022 |
Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients.
Topics: Adult; Age Factors; Area Under Curve; Body Surface Area; Burns; Comorbidity; Debridement; Diabetes M | 2019 |
Novel Temperature Trajectory Subphenotypes in COVID-19.
Topics: Adult; Age Factors; Aged; Antipyretics; Bilirubin; Black or African American; Body Mass Index; Body | 2020 |
Clinical pearls in pulmonary diseases.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Asthma; Confusion; Cough; Female; Heart | 2017 |
The value of lactate clearance in admission decisions of patients with acute exacerbation of COPD.
Topics: Aged; Biomarkers; Cross-Sectional Studies; Decision Making; Emergency Service, Hospital; Female; Fol | 2018 |
Critical Velocity Determined by a Non-Exhaustive Method in Subjects With COPD.
Topics: Aged; Anaerobic Threshold; Cross-Sectional Studies; Exercise Tolerance; Female; Heart Rate; Humans; | 2018 |
Risk factors and outcomes of sepsis-induced myocardial dysfunction and stress-induced cardiomyopathy in sepsis or septic shock: A comparative retrospective study.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Cytokines; Diabetes Mellitus; Echocar | 2018 |
Base excess is superior to lactate-levels in prediction of ICU mortality after cardiac surgery.
Topics: Aged; Cardiopulmonary Bypass; Female; Hospital Mortality; Humans; Hyperlactatemia; Hypertension, Pul | 2018 |
Cardiovascular and respiratory dysfunction in chronic obstructive pulmonary disease complicated by impaired peripheral oxygenation.
Topics: Aged; Biomarkers; Cardiovascular System; Case-Control Studies; China; Cross-Sectional Studies; Echoc | 2015 |
TNF-α-induced NF-κB activation stimulates skeletal muscle glycolytic metabolism through activation of HIF-1α.
Topics: Animals; Case-Control Studies; Cell Line; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, a | 2015 |
Safety of metformin in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Biomarkers; Diabetes Mellitus, Type 2; Female; Hum | 2015 |
Monitoring the ionic content of exhaled breath condensate in various respiratory diseases by capillary electrophoresis with contactless conductivity detection.
Topics: Acetates; Adult; Aged; Ammonium Compounds; Asthma; Breath Tests; Butyrates; Calcium; Chlorides; Crow | 2015 |
Neutrophil targeted nano-drug delivery system for chronic obstructive lung diseases.
Topics: Animals; Drug Delivery Systems; Humans; Inflammation; Lactic Acid; Mice; Nanoparticles; Neutrophils; | 2016 |
Altered metabolic and transporter characteristics of vastus lateralis in chronic obstructive pulmonary disease.
Topics: Adenosine Triphosphate; Aged; Case-Control Studies; Down-Regulation; Energy Metabolism; Female; Forc | 2008 |
Post-exercise heart rate recovery in healthy, obeses, and COPD subjects: relationships with blood lactic acid and PaO2 levels.
Topics: Adult; Bicycling; Cardiovascular Diseases; Exercise Test; Female; Heart Rate; Humans; Lactic Acid; M | 2009 |
Higher skeletal muscular metabolic reserve capacity in COPD patients than healthy subjects.
Topics: Adult; Aged; Blood Pressure; Exercise; Exercise Tolerance; Female; Heart Rate; Humans; Lactic Acid; | 2009 |
Plasma ammonia response to incremental cycling and walking tests in COPD.
Topics: Adenosine Triphosphate; Aged; Ammonia; Bicycling; Biomarkers; Exercise Test; Exercise Tolerance; Fem | 2010 |
Lactic acid levels in patients with chronic obstructive pulmonary disease accomplishing unsupported arm exercises.
Topics: Acidosis, Lactic; Aged; Arm; Blood Pressure; Exercise; Exercise Test; Exercise Tolerance; Female; Fo | 2010 |
Quadriceps metabolism during constant workrate cycling exercise in chronic obstructive pulmonary disease.
Topics: Aged; Exercise Test; Exercise Tolerance; Female; Glycogen; Humans; Lactic Acid; Male; Muscle Contrac | 2011 |
Effects of exercise on mitochondrial DNA content in skeletal muscle of patients with COPD.
Topics: Aged; Case-Control Studies; DNA, Mitochondrial; Exercise; Humans; Lactic Acid; Middle Aged; Mitochon | 2011 |
Mechanism of greater oxygen desaturation during walking compared with cycling in patients with COPD.
Topics: Aged; Anaerobic Threshold; Exercise Test; Functional Residual Capacity; Humans; Lactic Acid; Oxygen; | 2011 |
Antioxidant encapsulated porous poly(lactide-co-glycolide) microparticles for developing long acting inhalation system.
Topics: Administration, Inhalation; Animals; Anthocyanins; Antioxidants; Cell Line; Drug Carriers; Female; H | 2011 |
Muscle and blood redox status after exercise training in severe COPD patients.
Topics: Aged; Case-Control Studies; Catalase; Cytokines; Exercise; Female; Glutathione; Humans; Inflammation | 2012 |
The role of low-level lactate production in airway inflammation in asthma.
Topics: Adult; Aged; Animals; Asthma; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cytokines; | 2012 |
A better response in exercise capacity after pulmonary rehabilitation in more severe COPD patients.
Topics: Aged; Exercise Test; Exercise Therapy; Exercise Tolerance; Female; Forced Expiratory Volume; Humans; | 2012 |
Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation.
Topics: Acidosis, Respiratory; Aged; Aged, 80 and over; Alkalosis, Respiratory; Blood Gas Analysis; Carbon D | 2012 |
Capillary electrophoresis--a new tool for ionic analysis of exhaled breath condensate.
Topics: Adult; Aged; Breath Tests; Electrophoresis, Capillary; Female; Humans; Ions; Lactic Acid; Male; Midd | 2012 |
Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles.
Topics: alpha-Crystallin B Chain; Animals; Anti-Inflammatory Agents; Cell Line; Drug Carriers; Heat-Shock Pr | 2013 |
Sinusoidal high-intensity exercise does not elicit ventilatory limitation in chronic obstructive pulmonary disease.
Topics: Exercise; Exercise Test; Exercise Tolerance; Female; Forced Expiratory Volume; Heart Rate; Humans; L | 2013 |
Influence of chronic hypoxemia on peripheral muscle function and oxidative stress in humans.
Topics: Aged; Chronic Disease; Electromyography; Evoked Potentials; Female; Glutathione; Humans; Hypoxia; La | 2004 |
Effect of exercise mode on oxygen uptake and blood gases in COPD patients.
Topics: Adult; Aged; Carbon Dioxide; Exercise; Exercise Test; Female; Forced Expiratory Volume; Humans; Lact | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Weaning failure from cardiovascular origin.
Topics: Cardiac Output, Low; Heart Failure; Humans; Lactic Acid; Oxygen; Pulmonary Disease, Chronic Obstruct | 2005 |
Arterial blood lactate is a useful guide to when rehabilitation should be instigated in COPD.
Topics: Activities of Daily Living; Aged; Exercise Test; Exercise Tolerance; Humans; Lactic Acid; Male; Musc | 2008 |
Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chl | 2008 |