lactic acid has been researched along with Polycystic Kidney Diseases in 1 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin was administrated through daily intraperitoneal injection from postnatal day 35 for 4 weeks." | 7.11 | Metformin induces lactate accumulation and accelerates renal cyst progression in Pkd1-deficient mice. ( Chang, MY; Chou, LF; Hsu, SH; Hung, CC; Ong, ACM; Tian, YC; Tsai, CY; Yang, CW; Yang, HY, 2022) |
| "Metformin was administrated through daily intraperitoneal injection from postnatal day 35 for 4 weeks." | 3.11 | Metformin induces lactate accumulation and accelerates renal cyst progression in Pkd1-deficient mice. ( Chang, MY; Chou, LF; Hsu, SH; Hung, CC; Ong, ACM; Tian, YC; Tsai, CY; Yang, CW; Yang, HY, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, MY | 1 |
| Tsai, CY | 1 |
| Chou, LF | 1 |
| Hsu, SH | 1 |
| Yang, HY | 1 |
| Hung, CC | 1 |
| Tian, YC | 1 |
| Ong, ACM | 1 |
| Yang, CW | 1 |
1 trial available for lactic acid and Polycystic Kidney Diseases
| Article | Year |
|---|---|
Metformin induces lactate accumulation and accelerates renal cyst progression in Pkd1-deficient mice.
Topics: Animals; Cysts; Disease Models, Animal; Female; Kidney; Lactic Acid; Male; Metformin; Mice; Mice, Tr | 2022 |