lactic acid has been researched along with Peripheral Nerve Injuries in 26 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Peripheral Nerve Injuries: Injuries to the PERIPHERAL NERVES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Introduction of autologous MSCs to a chitosan/PLGA scaffold improved the repair and rehabilitation of a large gap after peripheral nerve injury in dogs." | 3.78 | Joint use of a chitosan/PLGA scaffold and MSCs to bridge an extra large gap in dog sciatic nerve. ( Ding, F; Gu, X; Gu, Y; Hu, N; Liu, J; Liu, Y; Xue, C; Yang, Y, 2012) |
| " We observed that 1) the locomotor recovery pattern, analyzed with kinetic parameters and peroneal functional index, was superior in the GS and CT groups; 2) a muscle contraction was obtained in all groups after stimulation of the proximal nerve but the mechanical muscle properties (twitch and tetanus threshold) parameters indicated a fast to slow fiber transition in all operated groups; 3) the muscular atrophy was greater in animals from TM group; 4) the metabosensitive afferent responses to electrically induced fatigue and to two chemical agents (KCl and lactic acid) was altered in GS, CT and TM groups; 5) the empty collagen tube supported motor axonal regeneration." | 3.75 | Functional recovery after peripheral nerve injury and implantation of a collagen guide. ( Alluin, O; Chabas, JF; Decherchi, P; Feron, F; Garcia, S; Guinard, D; Lavaut, MN; Marqueste, T; Wittmann, C, 2009) |
| "Current treatments for peripheral nerve injuries include autografts, the gold standard, and commercially available nerve growth conduits (NGCs)." | 1.48 | Combining growth factor releasing microspheres within aligned nanofibers enhances neurite outgrowth. ( Avila, COC; Sundararaghavan, HG; Whitehead, TJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Zhang, Y | 1 |
| Jiang, YK | 1 |
| Li, JA | 1 |
| Wei, WF | 1 |
| Shi, MP | 1 |
| Wang, YB | 1 |
| Jia, GL | 1 |
| Valentino, C | 1 |
| Vigani, B | 1 |
| Zucca, G | 1 |
| Ruggeri, M | 1 |
| Marrubini, G | 1 |
| Boselli, C | 1 |
| Icaro Cornaglia, A | 1 |
| Sandri, G | 1 |
| Rossi, S | 1 |
| Yu, E | 1 |
| Chen, Z | 1 |
| Huang, Y | 1 |
| Wu, Y | 1 |
| Wang, Z | 1 |
| Wang, F | 1 |
| Wu, M | 1 |
| Xu, K | 1 |
| Peng, W | 1 |
| Gregory, H | 1 |
| Phillips, JB | 1 |
| Whitehead, TJ | 1 |
| Avila, COC | 1 |
| Sundararaghavan, HG | 1 |
| Ouyang, Y | 1 |
| Huang, C | 1 |
| Zhu, Y | 2 |
| Fan, C | 1 |
| Ke, Q | 1 |
| Zhang, XF | 1 |
| Coughlan, A | 1 |
| O'Shea, H | 1 |
| Towler, MR | 1 |
| Kehoe, S | 1 |
| Boyd, D | 1 |
| Lee, SH | 1 |
| Kim, IG | 1 |
| Jung, AR | 1 |
| Shrestha, KR | 1 |
| Lee, JH | 1 |
| Park, KD | 1 |
| Chung, BH | 1 |
| Kim, SW | 1 |
| Kim, KH | 1 |
| Lee, JY | 1 |
| Zhang, W | 1 |
| Gao, Y | 1 |
| Zhou, Y | 1 |
| Liu, J | 2 |
| Zhang, L | 2 |
| Long, A | 1 |
| Tang, P | 1 |
| Li, B | 1 |
| Qiu, T | 1 |
| Iyer, KS | 1 |
| Yan, Q | 1 |
| Yin, Y | 1 |
| Xie, L | 1 |
| Wang, X | 1 |
| Li, S | 1 |
| Tajdaran, K | 1 |
| Gordon, T | 1 |
| Wood, MD | 1 |
| Shoichet, MS | 1 |
| Borschel, GH | 1 |
| Wlaszczuk, A | 1 |
| Marcol, W | 1 |
| Kucharska, M | 1 |
| Wawro, D | 1 |
| Palen, P | 1 |
| Lewin-Kowalik, J | 1 |
| Liu, H | 1 |
| Lv, P | 1 |
| Wu, H | 1 |
| Zhang, K | 1 |
| Xu, F | 1 |
| Zheng, L | 1 |
| Zhao, J | 1 |
| Alluin, O | 3 |
| Wittmann, C | 1 |
| Marqueste, T | 3 |
| Chabas, JF | 2 |
| Garcia, S | 2 |
| Lavaut, MN | 2 |
| Guinard, D | 1 |
| Feron, F | 2 |
| Decherchi, P | 3 |
| Rao, G | 1 |
| Legré, R | 1 |
| Magalon, G | 1 |
| Xue, C | 1 |
| Hu, N | 1 |
| Gu, Y | 1 |
| Yang, Y | 1 |
| Liu, Y | 1 |
| Ding, F | 1 |
| Gu, X | 1 |
| Sekiguchi, H | 1 |
| Ii, M | 1 |
| Jujo, K | 1 |
| Thorne, T | 1 |
| Ito, A | 1 |
| Klyachko, E | 1 |
| Hamada, H | 1 |
| Kessler, JA | 1 |
| Tabata, Y | 1 |
| Kawana, M | 1 |
| Asahi, M | 1 |
| Hagiwara, N | 1 |
| Losordo, DW | 1 |
| Chuang, TH | 1 |
| Wilson, RE | 1 |
| Love, JM | 1 |
| Fisher, JP | 1 |
| Shah, SB | 1 |
| Alliez, JR | 1 |
| Jammes, Y | 1 |
| Chang, CJ | 1 |
| Hsu, SH | 1 |
| Verreck, G | 1 |
| Chun, I | 1 |
| Li, Y | 1 |
| Kataria, R | 1 |
| Zhang, Q | 1 |
| Rosenblatt, J | 1 |
| Decorte, A | 1 |
| Heymans, K | 1 |
| Adriaensen, J | 1 |
| Bruining, M | 1 |
| Van Remoortere, M | 1 |
| Borghys, H | 1 |
| Meert, T | 1 |
| Peeters, J | 1 |
| Brewster, ME | 1 |
| de Ruiter, GC | 1 |
| Onyeneho, IA | 1 |
| Liang, ET | 1 |
| Moore, MJ | 1 |
| Knight, AM | 1 |
| Malessy, MJ | 1 |
| Spinner, RJ | 1 |
| Lu, L | 1 |
| Currier, BL | 1 |
| Yaszemski, MJ | 1 |
| Windebank, AJ | 1 |
| Pierucci, A | 1 |
| de Duek, EA | 1 |
| de Oliveira, AL | 1 |
| Hadlock, T | 1 |
| Elisseeff, J | 1 |
| Langer, R | 1 |
| Vacanti, J | 1 |
| Cheney, M | 1 |
| Fabre, T | 1 |
| Schappacher, M | 1 |
| Bareille, R | 1 |
| Dupuy, B | 1 |
| Soum, A | 1 |
| Bertrand-Barat, J | 1 |
| Baquey, C | 1 |
| Madison, RD | 1 |
| da Silva, C | 1 |
| Dikkes, P | 1 |
| Sidman, RL | 1 |
| Chiu, TH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Examining the Efficacy of Low Intensity Low Frequency Surface Acoustic Wave Ultrasound(LILF/SAWU) in Trigeminal Neuralgia Pain[NCT01447108] | Phase 4 | 16 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Peripheral Nerve Injuries
| Article | Year |
|---|---|
Materials for peripheral nerve repair constructs: Natural proteins or synthetic polymers?
Topics: Animals; Biocompatible Materials; Chitosan; Collagen; Humans; Lactic Acid; Nerve Regeneration; Perip | 2021 |
25 other studies available for lactic acid and Peripheral Nerve Injuries
| Article | Year |
|---|---|
The effect of poly(lactic-co-glycolic acid) conduit loading insulin-like growth factor 1 modified by a collagen-binding domain on peripheral nerve injury in rats.
Topics: Animals; Collagen; Glycols; Insulin-Like Growth Factor I; Lactic Acid; Nerve Regeneration; Periphera | 2022 |
Design of Novel Mechanically Resistant and Biodegradable Multichannel Platforms for the Treatment of Peripheral Nerve Injuries.
Topics: Humans; Lactic Acid; Peripheral Nerve Injuries; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid | 2023 |
A grooved conduit combined with decellularized tissues for peripheral nerve regeneration.
Topics: Animals; Lactic Acid; Nerve Regeneration; Peripheral Nerve Injuries; Prostheses and Implants; Rats; | 2023 |
Combining growth factor releasing microspheres within aligned nanofibers enhances neurite outgrowth.
Topics: Animals; Biocompatible Materials; Cells, Cultured; Chick Embryo; Drug Delivery Systems; Elastic Modu | 2018 |
Fabrication of seamless electrospun collagen/PLGA conduits whose walls comprise highly longitudinal aligned nanofibers for nerve regeneration.
Topics: Animals; Collagen; Electrochemistry; Equipment Design; Equipment Failure Analysis; Guided Tissue Reg | 2013 |
Experimental composite guidance conduits for peripheral nerve repair: an evaluation of ion release.
Topics: Biocompatible Materials; Glass; Ions; Lactic Acid; Materials Testing; Nerve Regeneration; Peripheral | 2012 |
Combined effects of brain-derived neurotrophic factor immobilized poly-lactic-co-glycolic acid membrane with human adipose-derived stem cells and basic fibroblast growth factor hydrogel on recovery of erectile dysfunction.
Topics: Animals; Brain-Derived Neurotrophic Factor; Combined Modality Therapy; Drug Carriers; Drug Therapy, | 2014 |
Localized and sustained delivery of erythropoietin from PLGA microspheres promotes functional recovery and nerve regeneration in peripheral nerve injury.
Topics: Animals; Capsules; Delayed-Action Preparations; Diffusion; Erythropoietin; Lactic Acid; Male; Nerve | 2015 |
PRGD/PDLLA conduit potentiates rat sciatic nerve regeneration and the underlying molecular mechanism.
Topics: Animals; Axons; Biocompatible Materials; Biomimetics; Ciliary Neurotrophic Factor; Cystine; GAP-43 P | 2015 |
An engineered biocompatible drug delivery system enhances nerve regeneration after delayed repair.
Topics: Animals; Drug Delivery Systems; Glial Cell Line-Derived Neurotrophic Factor; Lactic Acid; Microspher | 2016 |
Poly(D,L-Lactide-Co-Glycolide) Tubes With Multifilament Chitosan Yarn or Chitosan Sponge Core in Nerve Regeneration.
Topics: Animals; Chitosan; Guided Tissue Regeneration; Lactic Acid; Male; Nerve Regeneration; Outcome Assess | 2016 |
Salidroside promotes peripheral nerve regeneration based on tissue engineering strategy using Schwann cells and PLGA: in vitro and in vivo.
Topics: Animals; Cell Line; Cells, Cultured; Glucosides; Lactic Acid; Nerve Growth Factors; Nerve Regenerati | 2017 |
Functional recovery after peripheral nerve injury and implantation of a collagen guide.
Topics: Afferent Pathways; Animals; Axons; Collagen; Electricity; Hindlimb; Implants, Experimental; Injectio | 2009 |
FK506 induces changes in muscle properties and promotes metabosensitive nerve fiber regeneration.
Topics: Animals; Disease Models, Animal; Growth Cones; Immunosuppressive Agents; Lactic Acid; Male; Muscle F | 2009 |
Joint use of a chitosan/PLGA scaffold and MSCs to bridge an extra large gap in dog sciatic nerve.
Topics: Animals; Biocompatible Materials; Bone Marrow; Chitosan; Dogs; Lactic Acid; Mesenchymal Stem Cell Tr | 2012 |
Estradiol promotes neural stem cell differentiation into endothelial lineage and angiogenesis in injured peripheral nerve.
Topics: Animals; Cell Differentiation; Cell Lineage; Cell Proliferation; Combined Modality Therapy; Endothel | 2013 |
A novel internal fixator device for peripheral nerve regeneration.
Topics: Animals; Axons; Lactic Acid; Male; Nerve Regeneration; Peripheral Nerve Injuries; Peripheral Nerves; | 2013 |
Neuromuscular rehabilitation by treadmill running or electrical stimulation after peripheral nerve injury and repair.
Topics: Action Potentials; Animals; Axons; Electric Stimulation; Female; Injections; Lactic Acid; Motor Acti | 2004 |
The effects of low-intensity ultrasound on peripheral nerve regeneration in poly(DL-lactic acid-co-glycolic acid) conduits seeded with Schwann cells.
Topics: Absorbable Implants; Animals; Guided Tissue Regeneration; Lactic Acid; Male; Nerve Regeneration; Per | 2004 |
Preparation and physicochemical characterization of biodegradable nerve guides containing the nerve growth agent sabeluzole.
Topics: Absorbable Implants; Animals; Biocompatible Materials; Body Fluids; Diffusion; Drug Implants; Drug S | 2005 |
Methods for in vitro characterization of multichannel nerve tubes.
Topics: Biocompatible Materials; Guided Tissue Regeneration; Implants, Experimental; Lactic Acid; Materials | 2008 |
Peripheral nerve regeneration through biodegradable conduits prepared using solvent evaporation.
Topics: Absorbable Implants; Animals; Axons; Basement Membrane; Biocompatible Materials; Female; Immunohisto | 2008 |
A tissue-engineered conduit for peripheral nerve repair.
Topics: Animals; Animals, Newborn; Biocompatible Materials; Bioprosthesis; Cells, Cultured; Implants, Experi | 1998 |
Study of a (trimethylenecarbonate-co-epsilon-caprolactone) polymer--part 2: in vitro cytocompatibility analysis and in vivo ED1 cell response of a new nerve guide.
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cell Division; Cells, Cultured; HeLa Cells; Humans; | 2001 |
Peripheral nerve regeneration with entubulation repair: comparison of biodegradeable nerve guides versus polyethylene tubes and the effects of a laminin-containing gel.
Topics: Animals; Biodegradation, Environmental; Horseradish Peroxidase; Lactates; Lactic Acid; Laminin; Male | 1987 |