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lactic acid and Parkinsonian Disorders

lactic acid has been researched along with Parkinsonian Disorders in 6 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Research Excerpts

ExcerptRelevanceReference
" The results obtained from this study demonstrate that nanotization of nicotine improves neuroprotective efficacy by enhancing its bioavailability and subsequent modulation in the indicators of oxidative stress and apoptosis."1.39Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism. ( Agarwal, S; Bhatnagar, P; Chaturvedi, RK; Chauhan, LKS; Gupta, KC; Kumar, P; Patel, DK; Singh, MP; Singhal, NK; Tiwari, MN; Tiwari, SK, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Li, J1
Chen, L1
Qin, Q1
Wang, D1
Zhao, J1
Gao, H1
Yuan, X1
Zhang, J1
Zou, Y1
Mao, Z1
Xiong, Y1
Min, Z1
Yan, M1
Wang, CY1
Xue, Z1
Tiwari, MN2
Agarwal, S2
Bhatnagar, P2
Singhal, NK2
Tiwari, SK2
Kumar, P2
Chauhan, LKS1
Patel, DK2
Chaturvedi, RK2
Singh, MP2
Gupta, KC2
Srivastava, G1
Brashket, S1
Negro, S2
Boeva, L1
Slowing, K2
Fernandez-Carballido, A2
Garcia-García, L1
Barcia, E2
Fernández, M1
Yang, X1
Chen, Y1
Hong, X1
Wu, N1
Song, L1
Yuan, W1
Liu, Z1

Other Studies

6 other studies available for lactic acid and Parkinsonian Disorders

ArticleYear
Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease.
    Neurobiology of disease, 2022, Volume: 163

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dopaminergic Neurons; Hexokinase; Humans; L-Lactate De

2022
Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liq

2013
Mechanism of Nanotization-Mediated Improvement in the Efficacy of Caffeine Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonism.
    Journal of biomedical nanotechnology, 2015, Volume: 11, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Active Transport, Cell Nucleus; Animals; Biological Tr

2015
Efficacy of Ropinirole-Loaded PLGA Microspheres for the Reversion of Rotenone- Induced Parkinsonism.
    Current pharmaceutical design, 2017, Volume: 23, Issue:23

    Topics: Animals; Antiparkinson Agents; Cell Line, Tumor; Cell Survival; Humans; Indoles; Insecticides; Lacti

2017
An effective novel delivery strategy of rasagiline for Parkinson's disease.
    International journal of pharmaceutics, 2011, Oct-31, Volume: 419, Issue:1-2

    Topics: Animals; Antiparkinson Agents; Brain; Delayed-Action Preparations; Disease Models, Animal; Fluorodeo

2011
Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats.
    Drug design, development and therapy, 2012, Volume: 6

    Topics: Animals; Antiparkinson Agents; Benserazide; Blotting, Western; Delayed-Action Preparations; Disease

2012