lactic acid has been researched along with Parkinsonian Disorders in 6 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results obtained from this study demonstrate that nanotization of nicotine improves neuroprotective efficacy by enhancing its bioavailability and subsequent modulation in the indicators of oxidative stress and apoptosis." | 1.39 | Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism. ( Agarwal, S; Bhatnagar, P; Chaturvedi, RK; Chauhan, LKS; Gupta, KC; Kumar, P; Patel, DK; Singh, MP; Singhal, NK; Tiwari, MN; Tiwari, SK, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Chen, L | 1 |
| Qin, Q | 1 |
| Wang, D | 1 |
| Zhao, J | 1 |
| Gao, H | 1 |
| Yuan, X | 1 |
| Zhang, J | 1 |
| Zou, Y | 1 |
| Mao, Z | 1 |
| Xiong, Y | 1 |
| Min, Z | 1 |
| Yan, M | 1 |
| Wang, CY | 1 |
| Xue, Z | 1 |
| Tiwari, MN | 2 |
| Agarwal, S | 2 |
| Bhatnagar, P | 2 |
| Singhal, NK | 2 |
| Tiwari, SK | 2 |
| Kumar, P | 2 |
| Chauhan, LKS | 1 |
| Patel, DK | 2 |
| Chaturvedi, RK | 2 |
| Singh, MP | 2 |
| Gupta, KC | 2 |
| Srivastava, G | 1 |
| Brashket, S | 1 |
| Negro, S | 2 |
| Boeva, L | 1 |
| Slowing, K | 2 |
| Fernandez-Carballido, A | 2 |
| Garcia-García, L | 1 |
| Barcia, E | 2 |
| Fernández, M | 1 |
| Yang, X | 1 |
| Chen, Y | 1 |
| Hong, X | 1 |
| Wu, N | 1 |
| Song, L | 1 |
| Yuan, W | 1 |
| Liu, Z | 1 |
6 other studies available for lactic acid and Parkinsonian Disorders
| Article | Year |
|---|---|
Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dopaminergic Neurons; Hexokinase; Humans; L-Lactate De | 2022 |
Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism.
Topics: Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liq | 2013 |
Mechanism of Nanotization-Mediated Improvement in the Efficacy of Caffeine Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Active Transport, Cell Nucleus; Animals; Biological Tr | 2015 |
Efficacy of Ropinirole-Loaded PLGA Microspheres for the Reversion of Rotenone- Induced Parkinsonism.
Topics: Animals; Antiparkinson Agents; Cell Line, Tumor; Cell Survival; Humans; Indoles; Insecticides; Lacti | 2017 |
An effective novel delivery strategy of rasagiline for Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Brain; Delayed-Action Preparations; Disease Models, Animal; Fluorodeo | 2011 |
Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats.
Topics: Animals; Antiparkinson Agents; Benserazide; Blotting, Western; Delayed-Action Preparations; Disease | 2012 |