Page last updated: 2024-10-17

lactic acid and Pancreatitis

lactic acid has been researched along with Pancreatitis in 30 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the ability of arterial blood lactic acid concentration to predict death within 28 days of admission of patients with severe acute pancreatitis (SAP) in the intensive care unit (ICU)."8.12Predictive value of arterial blood lactic acid concentration on the risk of all-cause death within 28 days of admission in patients with severe acute pancreatitis. ( Liu, H; Liu, Y; Shi, L; Wu, M; Zhang, H; Zhang, W, 2022)
"The aim of this study was to determine whether oxymatrine has a protective effect against acute pancreatitis (AP) in a rat model of L-arginine-induced AP."7.78Oxymatrine ameliorates L-arginine-induced acute pancreatitis in rats. ( Cui, J; Dong, M; Dong, Q; Rong, D; Wang, Y; Zhang, Z, 2012)
" We observed a patient with nonmetastatic breast cancer who died because of severe lactic acidosis (plasma lactate concentration = 27 mmol/l) after ingestion of 25 g of elemental germanium over a 2-months period."7.68Abuse of germanium associated with fatal lactic acidosis. ( Iten, PX; Krapf, R; Schaffner, T, 1992)
"The effect of endogenous pituitary and pancreatic beta-endorphins in the physiopathologic factors of acute pancreatitis and the effect of opiate antagonist naloxone in these conditions were studied."7.67Plasma beta-endorphin and the effect of naloxone on hemodynamic changes during experimental acute pancreatitis in dogs. ( Chung, YS; Ha, SS; Hiura, A; Nishiwaki, H; Satake, K; Umeyama, K, 1989)
"To evaluate the ability of arterial blood lactic acid concentration to predict death within 28 days of admission of patients with severe acute pancreatitis (SAP) in the intensive care unit (ICU)."4.12Predictive value of arterial blood lactic acid concentration on the risk of all-cause death within 28 days of admission in patients with severe acute pancreatitis. ( Liu, H; Liu, Y; Shi, L; Wu, M; Zhang, H; Zhang, W, 2022)
"Patients with pancreatitis, pneumonia and the general group all shared three common predictive features as core variables, arterial base excess, lactic acid and platelets."3.79Disease-based modeling to predict fluid response in intensive care units. ( Celi, LA; Cismondi, F; Fialho, AS; Finkelstein, SN; Reti, SR; Sousa, JM; Vieira, SM, 2013)
"The aim of this study was to determine whether oxymatrine has a protective effect against acute pancreatitis (AP) in a rat model of L-arginine-induced AP."3.78Oxymatrine ameliorates L-arginine-induced acute pancreatitis in rats. ( Cui, J; Dong, M; Dong, Q; Rong, D; Wang, Y; Zhang, Z, 2012)
" We observed a patient with nonmetastatic breast cancer who died because of severe lactic acidosis (plasma lactate concentration = 27 mmol/l) after ingestion of 25 g of elemental germanium over a 2-months period."3.68Abuse of germanium associated with fatal lactic acidosis. ( Iten, PX; Krapf, R; Schaffner, T, 1992)
"The effect of endogenous pituitary and pancreatic beta-endorphins in the physiopathologic factors of acute pancreatitis and the effect of opiate antagonist naloxone in these conditions were studied."3.67Plasma beta-endorphin and the effect of naloxone on hemodynamic changes during experimental acute pancreatitis in dogs. ( Chung, YS; Ha, SS; Hiura, A; Nishiwaki, H; Satake, K; Umeyama, K, 1989)
"Identification of at-risk patients with acute pancreatitis (AP) early on in the course of hospital admission remains a challenge."1.91The utility of the bedside index of severity in acute pancreatitis at prognosticating adverse outcomes. ( Anderson, F; Clarke, DL; Ferndale, L; Makofane, TN, 2023)
"Among 4425 acute pancreatitis patients, 3040 patients were diagnosed with moderate or severe acute pancreatitis, and 1028 patients had initial lactate measured."1.72Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis. ( Chen, Y; Gong, M; He, W; Liu, F; Liu, P; Lu, N; Shao, Q; Wan, J; Xia, L; Zeng, H; Zeng, J; Zhu, Y, 2022)
"We included adult patients with acute pancreatitis who were admitted to the intensive care unit in the study."1.72Association between lactate-to-albumin ratio and 28-days all-cause mortality in patients with acute pancreatitis: A retrospective analysis of the MIMIC-IV database. ( Li, DP; Liu, Q; Wang, M; Wang, QZ; Wu, MM; Yan, SJ; Yu, JJ; Zheng, HL, 2022)
"The rabbits were randomly divided into 3 groups: group A without any treatment, group B with single treatment of stilamin, and group C with treatment of saizen combined with stilamin."1.39Protective effects of saizen in combination with stilamin on intestinal mucosa of a rabbit model of severe acute pancreatitis. ( Li, B; Liu, H; Lu, Y; Xu, H; Yang, M; Yu, Y, 2013)
"Severe acute pancreatitis was induced in the first 2 groups by injecting 5% sodium taurocholate into the pancreatic duct, and the investigation period was 12 hours."1.38Beneficial effect of hypertonic saline resuscitation in a porcine model of severe acute pancreatitis. ( Ding, WW; Ke, L; Li, JS; Li, N; Li, WQ; Ni, HB; Sun, JK; Tong, ZH, 2012)
"Acute pancreatitis was induced by intraductal injection of 5% sodium taurodeoxycholate, and the animals were studied for 3 hours thereafter."1.31Experimental pancreatitis causes acute perturbation of energy metabolism in the intestinal wall. ( Andersson, R; Ederoth, P; Nordstrom, CH; Sun, Z, 2002)
"Acute pancreatitis was induced in 40 Sprague-Dawley rats by ligation of the main biliopancreatic duct."1.31Whole gut washout ameliorates the progression of acute experimental pancreatitis. ( Aksoy, F; Ozer, S; Vatansev, C; Yol, S, 2000)
"Sera was obtained from patients with pancreatic cancer ( n = 14) and chronic pancreatitis ( n = 9) and healthy control subjects ( n = 10)."1.31Putative pancreatic cancer-associated diabetogenic factor: 2030 MW peptide. ( Basso, D; Fogar, P; Gallo, N; Greco, E; Mazza, S; Pedrazzoli, S; Piva, MG; Plebani, M; Seraglia, R; Tiengo, A; Valerio, A, 2002)
"Patients with severe acute pancreatitis die of complications closely related to the systemic activation of protease cascades."1.30Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis. ( Adler, G; Dickneite, G; Lerch, MM; Lührs, H; Weidenbach, H; Yamaguchi, H, 1997)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.33)18.7374
1990's2 (6.67)18.2507
2000's5 (16.67)29.6817
2010's9 (30.00)24.3611
2020's10 (33.33)2.80

Authors

AuthorsStudies
Wu, M1
Shi, L1
Zhang, H1
Liu, H2
Liu, Y1
Zhang, W1
Doganay, F1
Ak, R1
Yilmaz, E1
He, L1
Wang, L1
Hou, H1
Wang, GY1
Shang, D1
Zhang, GX1
Song, HY1
Jiang, N1
Liu, HH1
Chen, HL1
Zeng, J3
Wan, J5
He, W5
Zhu, Y9
Zeng, H4
Liu, P4
Gong, M3
Liu, F3
Shao, Q3
Xia, L5
Chen, Y3
Lu, N5
Liu, Q1
Zheng, HL1
Wu, MM1
Wang, QZ1
Yan, SJ1
Wang, M1
Yu, JJ1
Li, DP1
Makofane, TN1
Clarke, DL1
Anderson, F1
Ferndale, L1
Montrazi, ET1
Sasson, K1
Agemy, L1
Peters, DC1
Brenner, O1
Scherz, A1
Frydman, L1
Kayipmaz, AE1
Gedikaslan, S1
Aydogan, RF1
Shu, W2
Chen, J2
Kalantar-Zadeh, K1
Uppot, RN1
Lewandrowski, KB1
Fialho, AS1
Celi, LA1
Cismondi, F1
Vieira, SM1
Reti, SR1
Sousa, JM1
Finkelstein, SN1
Yang, C1
Hu, T1
Cao, H1
Zhang, L1
Zhou, P1
He, G1
Song, X1
Tong, A1
Guo, G1
Yang, F1
Zhang, X1
Qian, Z1
Qi, X1
Zhou, L1
Zheng, Y1
Roca, B1
Bhoomagoud, M1
Jung, T1
Atladottir, J1
Kolodecik, TR1
Shugrue, C1
Chaudhuri, A1
Thrower, EC1
Gorelick, FS1
Nohé, B1
Ploppa, A1
Schmidt, V1
Unertl, K1
Zhang, Z1
Wang, Y1
Dong, M1
Cui, J1
Rong, D1
Dong, Q1
Ni, HB1
Ke, L1
Sun, JK1
Tong, ZH1
Ding, WW1
Li, WQ1
Li, N1
Li, JS1
Pynnönen, L1
Minkkinen, M1
Räty, S1
Sand, J1
Nordback, I1
Perner, A1
Tenhunen, J1
Lu, Y1
Yu, Y1
Yang, M1
Li, B1
Xu, H1
Ederoth, P1
Sun, Z1
Nordstrom, CH1
Andersson, R1
Schuster, HP1
Paterson, KR1
Paice, BJ1
Lawson, DH1
Yamaguchi, H1
Weidenbach, H1
Lührs, H1
Lerch, MM1
Dickneite, G1
Adler, G1
Yol, S1
Ozer, S1
Aksoy, F1
Vatansev, C1
Basso, D1
Valerio, A1
Seraglia, R1
Mazza, S1
Piva, MG1
Greco, E1
Fogar, P1
Gallo, N1
Pedrazzoli, S1
Tiengo, A1
Plebani, M1
Krapf, R1
Schaffner, T1
Iten, PX1
Satake, K1
Hiura, A1
Nishiwaki, H1
Ha, SS1
Chung, YS1
Umeyama, K1
Fulop, M1
Bock, J1
Ben-Ezra, J1
Antony, M1
Danzig, J1
Gage, JS1

Reviews

4 reviews available for lactic acid and Pancreatitis

ArticleYear
Adverse drug reactions to antiretroviral medication.
    Frontiers in bioscience (Landmark edition), 2009, 01-01, Volume: 14, Issue:5

    Topics: Anti-HIV Agents; Bone Diseases, Metabolic; Bone Marrow; Cardiovascular System; Drug Hypersensitivity

2009
[Volume replacement in intensive care medicine].
    Der Anaesthesist, 2011, Volume: 60, Issue:5

    Topics: Blood Pressure; Blood Volume; Cardiomyopathy, Dilated; Cholecystectomy; Colloids; Critical Care; Goa

2011
Prognostic value of blood lactate in critically ill patients.
    Resuscitation, 1984, Volume: 11, Issue:3-4

    Topics: Acidosis; Acute Disease; Heart Arrest; Humans; Hypnotics and Sedatives; Intensive Care Units; Lactat

1984
Undesired effects of biguanide therapy.
    Adverse drug reactions and acute poisoning reviews, 1984,Autumn, Volume: 3, Issue:3

    Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Drug Interact

1984

Other Studies

26 other studies available for lactic acid and Pancreatitis

ArticleYear
Predictive value of arterial blood lactic acid concentration on the risk of all-cause death within 28 days of admission in patients with severe acute pancreatitis.
    Postgraduate medicine, 2022, Volume: 134, Issue:2

    Topics: Acute Disease; Humans; Lactic Acid; Pancreatitis; Prognosis; Retrospective Studies; ROC Curve

2022
Predictive Performance of Lactate as a Mortality Predictor in Patients with Acute Pancreatitis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2022, Volume: 32, Issue:4

    Topics: Acute Disease; Aged; Female; Humans; Lactic Acid; Male; Pancreatitis; Predictive Value of Tests; ROC

2022
Bicarbonated Ringer's solution improves L-arg-induced acute pancreatitis in rats via the NF-κB and Nrf2 pathways.
    Scandinavian journal of gastroenterology, 2023, Volume: 58, Issue:3

    Topics: Acute Disease; Amylases; Animals; Antioxidants; Lactic Acid; Lipase; NF-E2-Related Factor 2; NF-kapp

2023
Qingyi decoction attenuates intestinal epithelial cell injury
    World journal of gastroenterology, 2022, Aug-07, Volume: 28, Issue:29

    Topics: Acute Disease; Amine Oxidase (Copper-Containing); Amylases; Animals; Caco-2 Cells; Calcineurin; Calc

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis.
    Disease markers, 2022, Volume: 2022

    Topics: Acute Disease; Biomarkers; Humans; Lactic Acid; Metabolic Clearance Rate; Pancreatitis; Prognosis

2022
Association between lactate-to-albumin ratio and 28-days all-cause mortality in patients with acute pancreatitis: A retrospective analysis of the MIMIC-IV database.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Acute Disease; Adult; Humans; Lactic Acid; Pancreatitis; Retrospective Studies; Serum Albumin

2022
The utility of the bedside index of severity in acute pancreatitis at prognosticating adverse outcomes.
    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 2023, Volume: 61, Issue:2

    Topics: Acute Disease; Ethanol; Female; Humans; Lactic Acid; Male; Pancreatitis; Retrospective Studies

2023
High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models.
    Scientific reports, 2023, Nov-15, Volume: 13, Issue:1

    Topics: Acute Disease; Animals; Deuterium; Disease Models, Animal; Humans; Lactic Acid; Magnetic Resonance I

2023
The laboratory parameters and scoring systems used to predict clinical outcomes in geriatric patients with acute pancreatitis.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:22

    Topics: Acute Disease; Aged; Female; Humans; Lactic Acid; Male; Pancreatitis; Prognosis; Retrospective Studi

2023
Initially elevated arterial lactate as an independent predictor of poor outcomes in severe acute pancreatitis.
    BMC gastroenterology, 2020, Apr-19, Volume: 20, Issue:1

    Topics: Adult; Aged; Arteries; Female; Humans; Intra-Abdominal Hypertension; Lactic Acid; Male; Middle Aged;

2020
Elevated arterial lactate level as an independent risk factor for pancreatic infection in moderately severe acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2019, Volume: 19, Issue:5

    Topics: Acute Disease; Adult; Aged; Female; Humans; Infections; Lactic Acid; Male; Middle Aged; Pancreatitis

2019
Case records of the Massachusetts General Hospital. Case 23-2013. A 54-year-old woman with abdominal pain, vomiting, and confusion.
    The New England journal of medicine, 2013, Jul-25, Volume: 369, Issue:4

    Topics: Abdominal Pain; Acidosis, Lactic; Confusion; Diabetes Mellitus, Type 2; Diagnosis, Differential; Fem

2013
Disease-based modeling to predict fluid response in intensive care units.
    Methods of information in medicine, 2013, Volume: 52, Issue:6

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Blood Pressure; Cohort Studies; Computer Simula

2013
Facile Construction of Chloroquine Containing PLGA-Based pDNA Delivery System for Efficient Tumor and Pancreatitis Targeting in Vitro and in Vivo.
    Molecular pharmaceutics, 2015, Jun-01, Volume: 12, Issue:6

    Topics: Animals; Calorimetry, Differential Scanning; Chloroquine; HEK293 Cells; Humans; Lactic Acid; Male; M

2015
Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adenosine Triphosphatases; Amylases; Animals; Carbachol; Ceruletide; Chymotrypsin; Enzyme Activation

2009
Oxymatrine ameliorates L-arginine-induced acute pancreatitis in rats.
    Inflammation, 2012, Volume: 35, Issue:2

    Topics: Alkaloids; Amine Oxidase (Copper-Containing); Amylases; Animals; Arginine; Claudin-1; Intestine, Sma

2012
Beneficial effect of hypertonic saline resuscitation in a porcine model of severe acute pancreatitis.
    Pancreas, 2012, Volume: 41, Issue:2

    Topics: Acute Disease; Animals; Biomarkers; Creatinine; Disease Models, Animal; Enzymes; Female; Hemodynamic

2012
Luminal lactate in acute pancreatitis--validation and relation to disease severity.
    BMC gastroenterology, 2012, Apr-30, Volume: 12

    Topics: Adult; Aged; Biomarkers; C-Reactive Protein; Cohort Studies; Critical Care; Female; Humans; Lactic A

2012
Protective effects of saizen in combination with stilamin on intestinal mucosa of a rabbit model of severe acute pancreatitis.
    Pancreas, 2013, Volume: 42, Issue:1

    Topics: Acute Disease; Animals; Apoptosis; Biomarkers; Caspase 3; Cytoprotection; Disease Models, Animal; Dr

2013
Experimental pancreatitis causes acute perturbation of energy metabolism in the intestinal wall.
    Pancreas, 2002, Volume: 25, Issue:3

    Topics: Animals; Area Under Curve; Energy Metabolism; Glucose; Intestine, Small; Lactic Acid; Liver; Male; M

2002
Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis.
    Gut, 1997, Volume: 40, Issue:4

    Topics: Acute Disease; Amylases; Animals; Antithrombin III; Biomarkers; Ceruletide; Complement C1 Inactivato

1997
Whole gut washout ameliorates the progression of acute experimental pancreatitis.
    American journal of surgery, 2000, Volume: 180, Issue:2

    Topics: Acute Disease; Alanine Transaminase; Amylases; Animals; Bicarbonates; Blood Glucose; Calcium; Diseas

2000
Putative pancreatic cancer-associated diabetogenic factor: 2030 MW peptide.
    Pancreas, 2002, Volume: 24, Issue:1

    Topics: Adult; Aged; Animals; Cells, Cultured; Culture Media, Conditioned; Female; Glucose; Humans; Lactic A

2002
Abuse of germanium associated with fatal lactic acidosis.
    Nephron, 1992, Volume: 62, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Female; Germanium; Hum

1992
Plasma beta-endorphin and the effect of naloxone on hemodynamic changes during experimental acute pancreatitis in dogs.
    Surgery, gynecology & obstetrics, 1989, Volume: 168, Issue:5

    Topics: Acute Disease; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Blood Pressure; Cardiac Output;

1989
Plasma lactate and 3-hydroxybutyrate levels in patients with acute ethanol intoxication.
    The American journal of medicine, 1986, Volume: 80, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acute Disease; Adult; Aged; Alcoholic Intoxication; Blood Glucose; Diabetic K

1986