Page last updated: 2024-10-17

lactic acid and Out-of-Hospital Cardiac Arrest

lactic acid has been researched along with Out-of-Hospital Cardiac Arrest in 51 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Out-of-Hospital Cardiac Arrest: Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of the glucagon-like peptide-1 analog exenatide on blood glucose, lactate clearance, and hemodynamic variables in comatose, resuscitated out-of-hospital cardiac arrest patients."9.27The Glucagon-Like Peptide-1 Analog Exenatide Increases Blood Glucose Clearance, Lactate Clearance, and Heart Rate in Comatose Patients After Out-of-Hospital Cardiac Arrest. ( Engstrøm, T; Frydland, M; Hassager, C; Høfsten, DE; Kjaergaard, J; Køber, L; Lindholm, MG; Møller, JE; Schmidt, H; Thomsen, JH; Wiberg, S; Winther-Jensen, M, 2018)
"To investigate the effects of the glucagon-like peptide-1 analog exenatide on blood glucose, lactate clearance, and hemodynamic variables in comatose, resuscitated out-of-hospital cardiac arrest patients."5.27The Glucagon-Like Peptide-1 Analog Exenatide Increases Blood Glucose Clearance, Lactate Clearance, and Heart Rate in Comatose Patients After Out-of-Hospital Cardiac Arrest. ( Engstrøm, T; Frydland, M; Hassager, C; Høfsten, DE; Kjaergaard, J; Køber, L; Lindholm, MG; Møller, JE; Schmidt, H; Thomsen, JH; Wiberg, S; Winther-Jensen, M, 2018)
" As for patients, inclusion criteria were: 1) age ≥18 years; 2) non-traumatic out-of-hospital cardiac arrest with return of spontaneous circulation; 3) lactic acid measured within one hour of return of circulation."3.77The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest. ( Carney, E; Cocchi, MN; Donnino, MW; Farris, S; Howell, MD; Hunziker, S; Joyce, N; Miller, J; Salciccioli, J; Zimetbaum, P, 2011)
"Relative tachycardia is associated with poor neurological outcomes in post-cardiac arrest patients, independent of TH, and with higher serum lactate levels and admission SOFA scores."1.51Relative tachycardia is associated with poor outcomes in post-cardiac arrest patients regardless of therapeutic hypothermia. ( Jo, YH; Jung, YS; Kim, K; Kim, KS; Kim, T; Ko, JI; Kwon, WY; Shin, J; Shin, SM; Suh, GJ, 2019)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's33 (64.71)24.3611
2020's18 (35.29)2.80

Authors

AuthorsStudies
Zhang, M1
Zhang, Q1
Yu, Y1
An, L1
Qi, Z1
Li, C1
Kokulu, K1
Sert, ET1
Kim, HJ1
Michael, K1
Wee, JH2
Oh, JS2
Kim, WY2
Cho, IS4
Lee, MJ1
Lee, DH3
Kim, YH1
Youn, CS2
Wang, H1
Lan, C1
Luo, Y1
Zhang, T1
Cocchi, MN5
Salciccioli, J3
Yankama, T2
Chase, M2
Patel, PV1
Liu, X2
Mader, TJ1
Donnino, MW6
Rosenberg, RD1
Guo, CC1
Chatterjee, S1
Schreyer, KE1
Bashir, R1
O'Murchu, B1
Aggarwal, V1
DeAngelis, M1
Edmundowicz, D1
O'Neill, BP1
Young, PJ1
Nickson, CP1
Perner, A1
Gue, YX1
Sayers, M1
Whitby, BT1
Kanji, R1
Adatia, K1
Smith, R1
Davies, WR1
Perperoglou, A1
Potpara, TS1
Lip, GYH1
Gorog, DA1
Okada, Y1
Kiguchi, T1
Irisawa, T1
Yoshiya, K1
Yamada, T1
Hayakawa, K1
Noguchi, K1
Nishimura, T1
Ishibe, T1
Yagi, Y1
Kishimoto, M1
Shintani, H1
Hayashi, Y1
Sogabe, T1
Morooka, T1
Sakamoto, H1
Suzuki, K1
Nakamura, F1
Nishioka, N1
Matsuyama, T1
Matsui, S1
Shimazu, T1
Koike, K1
Kawamura, T1
Kitamura, T1
Iwami, T1
Tabi, M1
Burstein, BJ1
Ahmed, A1
Dezfulian, C1
Kashani, KB1
Jentzer, JC1
Moskowitz, A1
Andersen, LW3
Rittenberger, JC2
Swor, R1
Seethala, RR1
Kurz, MC1
Berg, KM2
Grossestreuer, AV2
Holmberg, MJ1
Callaway, CW2
Nee, J1
Koerner, R1
Zickler, D1
Schroeder, T1
Enghard, P1
Nibbe, L1
Hasper, D1
Buder, R1
Leithner, C1
Ploner, CJ1
Eckardt, KU1
Storm, C1
Kruse, JM1
Issa, MS1
Patel, H1
Ntshinga, L1
Coker, A1
Son, SH1
In, YN1
Park, JS1
You, Y1
Min, JH2
Yoo, I1
Cho, YC1
Jeong, W1
Ahn, HJ1
Kang, C1
Lee, BK2
Lonsain, WS1
De Lausnay, L1
Wauters, L1
Desruelles, D1
Dewolf, P1
Freire Jorge, P1
Boer, R1
Posma, RA1
Harms, KC1
Hiemstra, B1
Bens, BWJ1
Nijsten, MW1
Mölström, S2
Nielsen, TH2
Nordström, CH2
Forsse, A1
Möller, S2
Venö, S1
Mamaev, D1
Tencer, T1
Schmidt, H3
Toft, P2
Hayashida, K1
Suzuki, M1
Yonemoto, N1
Hori, S1
Tamura, T1
Sakurai, A1
Tahara, Y1
Nagao, K1
Yaguchi, A1
Morimura, N1
Wiberg, S1
Kjaergaard, J6
Thomsen, JH2
Frydland, M2
Winther-Jensen, M1
Lindholm, MG3
Høfsten, DE1
Engstrøm, T1
Køber, L1
Møller, JE3
Hassager, C7
Graeff, I1
Schacher, S1
Lenkeit, S1
Widmann, CN1
Schewe, JC1
Laurikkala, J1
Skrifvars, MB1
Bäcklund, M1
Tiainen, M1
Bendel, S1
Karhu, J1
Varpula, T1
Vaahersalo, J1
Pettilä, V1
Wilkman, E1
Hohmann, C1
Pfister, R3
Michels, G2
Adler, C2
Paul, C1
Hinkelbein, J1
Krings, A1
Lechleuthner, A1
Stangl, R1
Lee, SH2
Oh, JH1
Lee, YH2
Han, C1
Choi, WJ2
Sohn, YD1
Düring, J1
Dankiewicz, J2
Cronberg, T1
Hovdenes, J1
Kuiper, M1
Nielsen, N3
Pellis, T1
Stammet, P2
Vulto, J1
Wanscher, M4
Wise, M1
Åneman, A1
Friberg, H3
Ko, JI1
Kim, KS1
Suh, GJ1
Kim, K1
Kwon, WY1
Shin, J1
Jo, YH1
Jung, YS1
Kim, T1
Shin, SM1
Gilje, P1
Bro-Jeppesen, J4
Rundgren, M1
Devaux, Y1
Al-Mashat, M1
Jögi, J1
Erlinge, D2
Kim, CS1
Vassallo, MC1
Tartamella, F1
Bhakta, P1
Han, KS1
Kim, SJ1
Lee, EJ1
Park, KY1
Lee, JY1
Lee, SW1
Kjærgaard, J1
Kong, T1
Chung, SP1
Lee, HS1
Kim, S1
Lee, J1
Hwang, SO1
Shin, SD1
Song, KJ1
Cha, KC1
You, JS1
Grand, J1
Boesgaard, S1
Giberson, T1
Gaieski, DF1
Abella, BS1
Peberdy, MA1
Ornato, J1
Clore, J1
Grossestreuer, A1
Taccone, FS1
Donadello, K2
Dell'Anna, AM1
Kaji, AH1
Hanif, AM1
Bosson, N1
Ostermayer, D1
Niemann, JT1
Annborn, M1
Wise, MP1
Pelosi, P1
De Backer, DP1
Min, YI1
Kim, SH1
Ostenfeld, S1
Baldus, S1
Reuter, H1
Williams, TA1
Martin, R1
Celenza, A1
Bremner, A1
Fatovich, D1
Krause, J1
Arena, S1
Finn, J1
Kurowski, A1
Czyzewski, L1
Smereka, J1
Szarpak, L1
Hifumi, T1
Kawakita, K1
Yoda, T1
Okazaki, T1
Kuroda, Y1
Debaty, G1
Babaz, V1
Durand, M1
Gaide-Chevronnay, L1
Fournel, E1
Blancher, M1
Bouvaist, H1
Chavanon, O1
Maignan, M1
Bouzat, P1
Albaladejo, P1
Labarère, J1
Orban, JC1
Novain, M1
Cattet, F1
Plattier, R1
Nefzaoui, M1
Hyvernat, H1
Raguin, O1
Kaidomar, M1
Kerever, S1
Ichai, C1
Miller, J1
Hunziker, S1
Carney, E1
Farris, S1
Joyce, N1
Zimetbaum, P1
Howell, MD1
Karagiannis, C1
Georgiou, M1
Kouskouni, E1
Iacovidou, N1
Xanthos, T1
Viersen, VA1
Greuters, S1
Korfage, AR1
Van der Rijst, C1
Van Bochove, V1
Nanayakkara, PW1
Vandewalle, E1
Boer, C1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neuromuscular Blockade for Post-Cardiac Arrest Care[NCT02260258]Phase 283 participants (Actual)Interventional2014-10-31Completed
GLP-1 Analogs for Neuroprotection After Out-of-hospital Cardiac Arrest, a Randomized Clinical Trail[NCT02442791]120 participants (Actual)Interventional2014-06-30Completed
Bedside Monitoring of Cerebral Energy State During the Peri-cardiac Arrest Period - Blood Pressure Targets in Post Resuscitation Care[NCT03095742]60 participants (Actual)Interventional2017-09-01Completed
Target Temperature Management 33°C Versus 36°C After Out-of-hospital Cardiac Arrest, a Randomised, Parallel Groups, Assessor Blinded Clinical Trial[NCT01020916]950 participants (Anticipated)Interventional2010-11-30Completed
The Effect of Intra Aortic Balloon Pump Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary Syndrome[NCT03638609]102 participants (Anticipated)Interventional2017-10-23Recruiting
Evaluation of the Heart's Respiratory Quotient as Predictive Value After Extra-hospital[NCT04211207]40 participants (Actual)Observational2020-01-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Lactate Over 24 Hours

Change in median serum lactate level between enrollment and 24-hours after the receipt of study drug. A negative number indicates that the lactate levels were lower at 24 hours compared to their level at receipt of study drug. (NCT02260258)
Timeframe: 24 hours

Interventionmmol/L (Number)
Rocuronium-2.2
Usual Care-2.3

Change in Lactate Over 24 Hours: Effect Estimate

Interaction between allocated treatment and time: ratio of geometric mean differences over 24 hours in log lactate values between the two groups. (NCT02260258)
Timeframe: 24 hours

InterventionRatio (Number)
Effect Estimate1.3

Muscle Weakness Score

"Medical Research Council Scale : Measured for 6 muscle groups (3 in the upper limbs and 3 in the lower limbs). Maximum score is 30 (grade 5 for each group) and minimum is 0 (grade 0 for each group). If muscle group strength was not symmetric bilaterally, higher measurement used. Higher scores indicate better outcomes.~Grade 5: Muscle contracts normally against full resistance. Grade 4: Muscle strength is reduced but muscle contraction can still move joint against resistance.~Grade 3: Muscle strength is further reduced such that the joint can be moved only against gravity with the examiner's resistance completely removed.~Grade 2: Muscle can move only if the resistance of gravity is removed. As an example, the elbow can be fully flexed only if the arm is maintained in a horizontal plane.~Grade 1: Only a trace or flicker of movement is seen or felt in the muscle or fasciculations are observed in the muscle.~Grade 0: No movement is observed" (NCT02260258)
Timeframe: Duration of hospitalization, limit 180 days

InterventionPoints (Median)
Rocuronium30
Usual Care30

Number of Participants With Rankin Score ≤3

"Modified Rankin scale to assess neurological outcome at discharge. The scale ranges from 0 to 6, and is used for measuring the performance of daily activities. The score is as follows:~0: No symptoms~1: No significant disability (able to carry out all usual activities, despite some symptoms)~2: Slight disability (able to look after own affairs without assistance, but unable to carry out all previous activities)~3: Moderate disability (requires some help, but able to walk unassisted)~4: Moderately severe disability (unable to attend to own bodily needs without assistance, and unable to walk unassisted)~5: Severe disability (requires constant nursing care and attention, bedridden, incontinent)~6: Dead.~Higher cores represent worse outcomes. Good and bad neurological outcome will be defined as a score of 0-3 and 4-6 respectively. This outcome reports the number of patients with a good neurological outcome( modified Rankin score ≤ 3)" (NCT02260258)
Timeframe: Duration of hospitalization, limit 180 days

InterventionParticipants (Count of Participants)
Rocuronium11
Usual Care9

Survival

In-hospital survival (NCT02260258)
Timeframe: Duration of hospitalization, limit 180 days

InterventionParticipants (Count of Participants)
Rocuronium14
Usual Care14

Time ROSC to Target Temperature

Time from return of spontaneous circulation to target temperature (NCT02260258)
Timeframe: Duration of hospitalization, limit 180 days

InterventionHours (Median)
Rocuronium6.8
Usual Care8.3

Length of Intensive Care Unit (ICU) Stay

Length of stay in ICU (NCT02260258)
Timeframe: Length of Stay Truncated at 28 Days

,
Interventiondays (Median)
All patientsICU survivors
Rocuronium6.09.0
Usual Care4.05.0

Mechanical Ventilation Duration

Mechanical Ventilation Duration in Hours (NCT02260258)
Timeframe: Duration of hospitalization, limit 180 days

,
InterventionHours (Median)
All patientsSurvivors to extubation
Rocuronium102.0126.3
Usual Care82.766.9

Reviews

1 review available for lactic acid and Out-of-Hospital Cardiac Arrest

ArticleYear
Prognostic factors for extracorporeal cardiopulmonary resuscitation recipients following out-of-hospital refractory cardiac arrest. A systematic review and meta-analysis.
    Resuscitation, 2017, Volume: 112

    Topics: Adult; Aged; Cardiopulmonary Resuscitation; Extracorporeal Membrane Oxygenation; Female; Humans; Lac

2017

Trials

10 trials available for lactic acid and Out-of-Hospital Cardiac Arrest

ArticleYear
Continuous Neuromuscular Blockade Following Successful Resuscitation From Cardiac Arrest: A Randomized Trial.
    Journal of the American Heart Association, 2020, Volume: 9, Issue:17

    Topics: Aged; Cardiopulmonary Resuscitation; Female; Humans; Hypothermia, Induced; Infusions, Intravenous; L

2020
Bedside microdialysis for detection of early brain injury after out-of-hospital cardiac arrest.
    Scientific reports, 2021, 08-05, Volume: 11, Issue:1

    Topics: Adult; Aged; Biomarkers; Brain; Brain Injuries; Brain Ischemia; Cerebral Veins; Energy Metabolism; F

2021
The Glucagon-Like Peptide-1 Analog Exenatide Increases Blood Glucose Clearance, Lactate Clearance, and Heart Rate in Comatose Patients After Out-of-Hospital Cardiac Arrest.
    Critical care medicine, 2018, Volume: 46, Issue:2

    Topics: Blood Glucose; Coma; Double-Blind Method; Exenatide; Female; Glucagon-Like Peptide 1; Heart Rate; He

2018
Early Lactate Values After Out-of-Hospital Cardiac Arrest: Associations With One-Year Outcome.
    Shock (Augusta, Ga.), 2019, Volume: 51, Issue:2

    Topics: Aged; Biomarkers; Disease-Free Survival; Female; Humans; Intensive Care Units; Lactic Acid; Length o

2019
Lactate, lactate clearance and outcome after cardiac arrest: A post-hoc analysis of the TTM-Trial.
    Acta anaesthesiologica Scandinavica, 2018, Volume: 62, Issue:10

    Topics: Aged; Female; Humans; Lactic Acid; Logistic Models; Male; Metabolic Clearance Rate; Middle Aged; Out

2018
The association between plasma miR-122-5p release pattern at admission and all-cause mortality or shock after out-of-hospital cardiac arrest.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2019, Volume: 24, Issue:1

    Topics: Aged; Cardiopulmonary Resuscitation; Case-Control Studies; Female; Humans; Lactic Acid; Male; MicroR

2019
Continuous neuromuscular blockade infusion for out-of-hospital cardiac arrest patients treated with targeted temperature management: A multicenter randomized controlled trial.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Aged; Biomarkers; Female; Humans; Hypothermia, Induced; Lactic Acid; Length of Stay; Male; Middle Ag

2018
Design paper of the "Blood pressure targets in post-resuscitation care and bedside monitoring of cerebral energy state: a randomized clinical trial".
    Trials, 2019, Jun-10, Volume: 20, Issue:1

    Topics: Blood Pressure; Brain; Cardiopulmonary Resuscitation; Double-Blind Method; Energy Metabolism; Humans

2019
Cardiac output, heart rate and stroke volume during targeted temperature management after out-of-hospital cardiac arrest: Association with mortality and cause of death.
    Resuscitation, 2019, Volume: 142

    Topics: Aged; Arterial Pressure; Brain Death; Cardiac Output; Cardiopulmonary Resuscitation; Cause of Death;

2019
Hemodynamics and vasopressor support during targeted temperature management at 33°C Versus 36°C after out-of-hospital cardiac arrest: a post hoc study of the target temperature management trial*.
    Critical care medicine, 2015, Volume: 43, Issue:2

    Topics: Age Factors; Aged; Body Temperature; Comorbidity; Dose-Response Relationship, Drug; Female; Hemodyna

2015

Other Studies

40 other studies available for lactic acid and Out-of-Hospital Cardiac Arrest

ArticleYear
Effects of early hemodynamics, oxygen metabolism, and lactate dynamics on prognosis of post-cardiac arrest syndrome.
    Chinese medical journal, 2021, Nov-10, Volume: 135, Issue:3

    Topics: Cardiopulmonary Resuscitation; Hemodynamics; Humans; Hypothermia, Induced; Lactic Acid; Out-of-Hospi

2021
The role of the lactate/albumin ratio in predicting survival outcomes in patients resuscitated after out-of-hospital cardiac arrest: A preliminary report.
    The American journal of emergency medicine, 2021, Volume: 50

    Topics: Aged; Emergency Service, Hospital; Female; Hospitalization; Humans; Lactic Acid; Male; Middle Aged;

2021
Coagulation measures after cardiac arrest (CMACA).
    PloS one, 2023, Volume: 18, Issue:1

    Topics: Blood Coagulation; Cardiopulmonary Resuscitation; Humans; Lactic Acid; Out-of-Hospital Cardiac Arres

2023
[Prognostic value of hemoglobin-to-red cell distribution width ratio in patients with cardiopulmonary resuscitation after out-of-hospital cardiac arrest].
    Zhonghua wei zhong bing ji jiu yi xue, 2023, Volume: 35, Issue:9

    Topics: Cardiopulmonary Resuscitation; Erythrocyte Indices; Hemoglobins; Humans; Intensive Care Units; Lacti

2023
Predicting Outcome After Out-of-Hospital Cardiac Arrest: Lactate, Need for Vasopressors, and Cytochrome
    Journal of intensive care medicine, 2020, Volume: 35, Issue:12

    Topics: Cytochromes c; Humans; Lactic Acid; Out-of-Hospital Cardiac Arrest; Prognosis; Prospective Studies;

2020
The prognostic value of initial serum lactate for survival in postcardiac arrest patients undergoing cardiac catheterization.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 02-01, Volume: 97, Issue:2

    Topics: Cardiac Catheterization; Cardiopulmonary Resuscitation; Female; Humans; Lactic Acid; Out-of-Hospital

2021
When Should Clinicians Act on Non-Statistically Significant Results From Clinical Trials?
    JAMA, 2020, Jun-09, Volume: 323, Issue:22

    Topics: Acute Kidney Injury; Coronary Angiography; Evidence-Based Practice; Fluid Therapy; Humans; Hydroxyet

2020
Usefulness of the NULL-PLEASE Score to Predict Survival in Out-of-Hospital Cardiac Arrest.
    The American journal of medicine, 2020, Volume: 133, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiopulmonary Resuscitation; Electric Countershock; Female;

2020
Predictive accuracy of biomarkers for survival among cardiac arrest patients with hypothermia: a prospective observational cohort study in Japan.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2020, Aug-05, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Female; Humans; Hydrogen-Ion

2020
Shock Severity and Hospital Mortality In Out of Hospital Cardiac Arrest Patients Treated With Targeted Temperature Management.
    Shock (Augusta, Ga.), 2021, 01-01, Volume: 55, Issue:1

    Topics: Aged; Arterial Pressure; Female; Hospital Mortality; Humans; Hypothermia, Induced; Lactic Acid; Logi

2021
Establishment of an extracorporeal cardio-pulmonary resuscitation program in Berlin - outcomes of 254 patients with refractory circulatory arrest.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2020, Sep-23, Volume: 28, Issue:1

    Topics: Acidosis; Adult; Aged; Berlin; Cardiopulmonary Resuscitation; Cohort Studies; Critical Pathways; Ext

2020
Lactate and hypotension as predictors of mortality after in-hospital cardiac arrest.
    Resuscitation, 2021, Volume: 158

    Topics: Adult; Cardiopulmonary Resuscitation; Hospitals; Humans; Hypotension; Lactic Acid; Out-of-Hospital C

2021
Cerebrospinal Fluid Lactate Levels, Brain Lactate Metabolism and Neurologic Outcome in Patients with Out-of-Hospital Cardiac Arrest.
    Neurocritical care, 2021, Volume: 35, Issue:1

    Topics: Brain; Humans; Hypothermia, Induced; Lactic Acid; Out-of-Hospital Cardiac Arrest; Prognosis; Retrosp

2021
The prognostic value of early lactate clearance for survival after out-of-hospital cardiac arrest.
    The American journal of emergency medicine, 2021, Volume: 46

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Lactic Acid; Male; Middle Aged; Out-of-H

2021
Early lactate and glucose kinetics following return to spontaneous circulation after out-of-hospital cardiac arrest.
    BMC research notes, 2021, May-13, Volume: 14, Issue:1

    Topics: Cardiopulmonary Resuscitation; Emergency Medical Services; Glucose; Humans; Kinetics; Lactic Acid; O

2021
Early Lactate Clearance Is Associated With Improved Outcomes in Patients With Postcardiac Arrest Syndrome: A Prospective, Multicenter Observational Study (SOS-KANTO 2012 Study).
    Critical care medicine, 2017, Volume: 45, Issue:6

    Topics: Aged; Aged, 80 and over; Biomarkers; Cardiopulmonary Resuscitation; Female; Humans; Japan; Lactic Ac

2017
Initial Blood Ammonia Level Is a Useful Prognostication Tool in Out-of-Hospital Cardiac Arrest - Multicenter Prospective Study (SOS-KANTO 2012 Study).
    Circulation journal : official journal of the Japanese Circulation Society, 2017, Nov-24, Volume: 81, Issue:12

    Topics: Aged; Aged, 80 and over; Ammonia; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Out-of

2017
Beyond the limits - ECPR in putative fatal circumstances.
    CJEM, 2018, Volume: 20, Issue:S2

    Topics: Blood Chemical Analysis; Cardiopulmonary Resuscitation; Female; Fever; Humans; Hydrogen-Ion Concentr

2018
[Are the initial pH and the lactate values after cardiopulmonary resuscitation always crucial?]
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019, Volume: 114, Issue:6

    Topics: Cardiopulmonary Resuscitation; Electric Countershock; Humans; Hydrogen-Ion Concentration; Lactic Aci

2019
[Which patients benefit from transport with ongoing cardiopulmonary resuscitation? : Retrospective analysis of 70 patients with refractory preclinical cardiac arrest].
    Der Anaesthesist, 2018, Volume: 67, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cardiopulmonary Resuscitation; Female; Germany; Glasgow Outcome Scal

2018
Optic nerve sheath diameter measured using early unenhanced brain computed tomography shows no correlation with neurological outcomes in patients undergoing targeted temperature management after cardiac arrest.
    Resuscitation, 2018, Volume: 128

    Topics: Adult; Aged; Brain; Cardiopulmonary Resuscitation; Female; Hospital Mortality; Humans; Hypothermia,

2018
Relative tachycardia is associated with poor outcomes in post-cardiac arrest patients regardless of therapeutic hypothermia.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:4

    Topics: Aged; Cardiopulmonary Resuscitation; Female; Humans; Hypothermia, Induced; Lactic Acid; Logistic Mod

2019
Can we trust power analysis on post hoc studies? A paradigm from out of hospital cardiac arrest.
    Acta anaesthesiologica Scandinavica, 2019, Volume: 63, Issue:6

    Topics: Cardiopulmonary Resuscitation; Humans; Lactic Acid; Out-of-Hospital Cardiac Arrest

2019
Impact of rapid lactate clearance as an indicator of hemodynamic optimization on outcome in out-of-hospital cardiac arrest: A retrospective analysis.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Aged; Cardiopulmonary Resuscitation; Female; Hemodynamics; Humans; Hypothermia, Induced; Lactic Acid

2019
The Prognostic Usefulness of the Lactate/Albumin Ratio for Predicting Clinical Outcomes in Out-of-Hospital Cardiac Arrest: a Prospective, Multicenter Observational Study (koCARC) Study.
    Shock (Augusta, Ga.), 2020, Volume: 53, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Lactic Acid; Male; Middle Aged; Nomograms; Out-of-Ho

2020
Initial lactate and lactate change in post-cardiac arrest: a multicenter validation study.
    Critical care medicine, 2014, Volume: 42, Issue:8

    Topics: Aged; Biomarkers; Female; Hospital Mortality; Humans; Hypothermia, Induced; Lactic Acid; Male; Middl

2014
Lactate measurement after cardiac arrest: tissue hypoxia or adaptive response?*.
    Critical care medicine, 2014, Volume: 42, Issue:8

    Topics: Female; Humans; Lactic Acid; Male; Out-of-Hospital Cardiac Arrest

2014
Predictors of neurologic outcome in patients resuscitated from out-of-hospital cardiac arrest using classification and regression tree analysis.
    The American journal of cardiology, 2014, Oct-01, Volume: 114, Issue:7

    Topics: Aged; California; Cardiopulmonary Resuscitation; Dose-Response Relationship, Drug; Epinephrine; Fema

2014
Lactate change after cardiopulmonary resuscitation: everything is in the baseline value!
    Critical care medicine, 2014, Volume: 42, Issue:12

    Topics: Female; Humans; Lactic Acid; Male; Out-of-Hospital Cardiac Arrest

2014
The authors reply.
    Critical care medicine, 2014, Volume: 42, Issue:12

    Topics: Female; Humans; Lactic Acid; Male; Out-of-Hospital Cardiac Arrest

2014
Correlation between initial serum levels of lactate after return of spontaneous circulation and survival and neurological outcomes in patients who undergo therapeutic hypothermia after cardiac arrest.
    Resuscitation, 2015, Volume: 88

    Topics: Adult; Aged; Cardiopulmonary Resuscitation; Female; Hemodynamics; Hospital Mortality; Humans; Hypoth

2015
Prognostic implication of out-of-hospital cardiac arrest in patients with cardiogenic shock and acute myocardial infarction.
    Resuscitation, 2015, Volume: 87

    Topics: Age Factors; Aged; Comorbidity; Denmark; Female; Humans; Lactic Acid; Male; Middle Aged; Myocardial

2015
[Mild therapeutic hypothermia in cardiogenic shock : Retrospective analysis of 80 patients with preclinical cardiac arrest due to cardiac causes].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2017, Volume: 112, Issue:1

    Topics: Comorbidity; Creatinine; Female; Humans; Hypothermia, Induced; Lactic Acid; Male; Middle Aged; Neuro

2017
Use of serum lactate levels to predict survival for patients with out-of-hospital cardiac arrest: A cohort study.
    Emergency medicine Australasia : EMA, 2016, Volume: 28, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Emergency Medical Services; Female; Humans; Lactic Acid;

2016
Blood lactate concentration after cardiac arrest resulting from myocardial infarction and outcome.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Myocardi

2016
Association of brain metabolites with blood lactate and glucose levels with respect to neurological outcomes after out-of-hospital cardiac arrest: A preliminary microdialysis study.
    Resuscitation, 2017, Volume: 110

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain; Cerebrovascular Circulation; Female; Humans; Hypother

2017
Association of serum lactate with outcome after out-of-hospital cardiac arrest treated with therapeutic hypothermia.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Aged; Female; Humans; Hypothermia, Induced; Intensive Care Units; Lactic Acid; Male; Middle Aged; Od

2017
The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest.
    Minerva anestesiologica, 2011, Volume: 77, Issue:11

    Topics: Aged; Area Under Curve; Calibration; Cohort Studies; Female; Heart Arrest; Humans; Lactic Acid; Logi

2011
The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest.
    Minerva anestesiologica, 2011, Volume: 77, Issue:11

    Topics: Aged; Area Under Curve; Calibration; Cohort Studies; Female; Heart Arrest; Humans; Lactic Acid; Logi

2011
The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest.
    Minerva anestesiologica, 2011, Volume: 77, Issue:11

    Topics: Aged; Area Under Curve; Calibration; Cohort Studies; Female; Heart Arrest; Humans; Lactic Acid; Logi

2011
The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest.
    Minerva anestesiologica, 2011, Volume: 77, Issue:11

    Topics: Aged; Area Under Curve; Calibration; Cohort Studies; Female; Heart Arrest; Humans; Lactic Acid; Logi

2011
Association of lactate levels with outcome after in-hospital cardiac arrest.
    Resuscitation, 2012, Volume: 83, Issue:8

    Topics: Adult; Cardiopulmonary Resuscitation; Greece; Humans; Lactic Acid; Out-of-Hospital Cardiac Arrest; R

2012
Hyperfibrinolysis in out of hospital cardiac arrest is associated with markers of hypoperfusion.
    Resuscitation, 2012, Volume: 83, Issue:12

    Topics: Aged; Blood Coagulation Disorders; Female; Fibrinolysis; Humans; Hydrogen-Ion Concentration; Lactic

2012