lactic acid has been researched along with Nervous System Disorders in 42 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Excerpt | Relevance | Reference |
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"We evaluated the ability of four biomarkers (C-Reactive protein (CRP), lactate, mid-regional proadrenomedullin (MR-proADM) and procalcitonin (PCT)) to detect each kind of organ failure considered in the SOFA in 213 patients with infection, sepsis or septic shock, by using multivariate regression analysis and calculation of the area under the receiver operating curve (AUROC)." | 3.96 | MR- proADM to detect specific types of organ failure in infection. ( Aldecoa, C; Almansa, R; Andaluz-Ojeda, D; Andrés, C; Bermejo-Martin, JF; Calvo, D; Cicuendez, R; Esteban-Velasco, MC; Martín, S; Martin-Fernandez, M; Muñoz-Bellvís, L; Nogales, L; Ríos-Llorente, A; Sanchez-Barrado, E; Vaquero-Roncero, LM, 2020) |
"The effect of lactic acidosis on neurological development in the first year of life." | 3.88 | Neurological impairments in hypoxic neonates and lactate levels. ( Jovandaric, MZ; Milenkovic, SJ, 2018) |
"23 studies involving 6720 cardiac arrest (CA) patients were included." | 2.58 | Blood Lactate or Lactate Clearance: Which Is Robust to Predict the Neurological Outcomes after Cardiac Arrest? A Systematic Review and Meta-Analysis. ( Liu, CF; Liu, LJ; Zhang, Z; Zhou, BC; Zhu, JJ, 2018) |
"Moderate to severe neonatal encephalopathy in asphyxiated term infants is associated with a high risk of cerebral palsy (especially quadriplegic or dyskinetic type) and/or cognitive disorders." | 2.44 | [Definition of intrapartum asphyxia and effects on outcome]. ( Zupan Simunek, V, 2008) |
"CSF LA in the groups with viral meningitis was not different compared to groups with non-infectious CNS diseases and chronic meningitis." | 1.35 | Quantitation of cerebrospinal fluid lactic acid in infectious and non-infectious neurological diseases. ( Berto, DB; Buczenko, GM; de Almeida, SM; de Goes Fontes, K; Faria, FL; Nogueira, MB; Raboni, SM; Vidal, LR, 2009) |
"Rabbits whose cerebral vasospasm were 50% or over 50% (n=7) and NSS is lesser than 3 were termed as groups 2, and rabbits whose cerebral vasospasm were 50% or above 50% (n=7) and NSS is greater than 3 were termed groups 3." | 1.34 | Lactate contents from cerebrospinal fluid in experimental subarachnoid hemorrhage, well correlate with vasospasm: ongoing and neurologic status. ( Ak, A; Cengiz, SL; Karaköse, S; Ustün, ME, 2007) |
"After 4 min of cardiac arrest, followed by 3 min of basic life support CPR, 17 animals were randomly assigned to receive, every 5 min, either a combination of vasopressin and epinephrine (vasopressin [IU/kg]/epinephrine [ micro g/kg]: 0." | 1.32 | Survival with full neurologic recovery after prolonged cardiopulmonary resuscitation with a combination of vasopressin and epinephrine in pigs. ( Klima, GCDN; Krismer, AC; Lindner, KH; Mayr, VD; Pechlaner, S; Rheinberger, K; Stadlbauer, KH; Voelckel, WG; Wagner-Berger, HG; Wenzel, V, 2003) |
"Lactate at 48 hours after cardiac arrest is an independent predictor of mortality and unfavorable neurologic outcome." | 1.32 | Serial lactate determinations for prediction of outcome after cardiac arrest. ( Havel, C; Holzer, M; Kliegel, A; Laggner, AN; Losert, H; Sterz, F; Zeiner, A, 2004) |
"122 had definite RCD, 38 neurological disorders other than RCD." | 1.31 | Diagnostic yield of the lactate stress test in 160 patients with suspected respiratory chain disorder. ( Finsterer, J; Milvay, E; Obermann, I, 2000) |
"Biotin deficiency associated with total parenteral nutrition is an emerging clinical problem; criteria for diagnosis and dosage for treatment are unclear." | 1.27 | Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic repercussions, and treatment. ( Baker, H; Baswell, DL; Holman, RT; Mock, DM; Sweetman, L, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (9.52) | 18.7374 |
1990's | 4 (9.52) | 18.2507 |
2000's | 9 (21.43) | 29.6817 |
2010's | 17 (40.48) | 24.3611 |
2020's | 8 (19.05) | 2.80 |
Authors | Studies |
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Rawat, A | 1 |
Morrison, BM | 1 |
Jarius, S | 1 |
Pache, F | 1 |
Körtvelyessy, P | 1 |
Jelčić, I | 1 |
Stettner, M | 1 |
Franciotta, D | 1 |
Keller, E | 1 |
Neumann, B | 1 |
Ringelstein, M | 1 |
Senel, M | 1 |
Regeniter, A | 1 |
Kalantzis, R | 1 |
Willms, JF | 1 |
Berthele, A | 1 |
Busch, M | 1 |
Capobianco, M | 1 |
Eisele, A | 1 |
Reichen, I | 1 |
Dersch, R | 1 |
Rauer, S | 1 |
Sandner, K | 1 |
Ayzenberg, I | 1 |
Gross, CC | 1 |
Hegen, H | 1 |
Khalil, M | 1 |
Kleiter, I | 1 |
Lenhard, T | 1 |
Haas, J | 1 |
Aktas, O | 1 |
Angstwurm, K | 1 |
Kleinschnitz, C | 1 |
Lewerenz, J | 1 |
Tumani, H | 1 |
Paul, F | 1 |
Stangel, M | 1 |
Ruprecht, K | 1 |
Wildemann, B | 1 |
Sood, N | 1 |
Sangari, A | 1 |
Goyal, A | 1 |
Conway, JAS | 1 |
Guo, W | 1 |
Ma, L | 1 |
Tuerhong, T | 1 |
Li, X | 1 |
Liu, B | 1 |
Xie, Z | 1 |
Yu, X | 1 |
Oh, TK | 1 |
Song, IA | 1 |
Bae, HJ | 1 |
Jeon, YT | 1 |
Romano, D | 1 |
Deiner, S | 1 |
Cherukuri, A | 1 |
Boateng, B | 1 |
Shrivastava, R | 1 |
Mocco, J | 1 |
Hadjipanayis, C | 1 |
Yong, R | 1 |
Kellner, C | 1 |
Yaeger, K | 1 |
Lin, HM | 2 |
Brallier, J | 1 |
Andrés, C | 1 |
Andaluz-Ojeda, D | 1 |
Cicuendez, R | 1 |
Nogales, L | 1 |
Martín, S | 1 |
Martin-Fernandez, M | 1 |
Almansa, R | 1 |
Calvo, D | 1 |
Esteban-Velasco, MC | 1 |
Vaquero-Roncero, LM | 1 |
Ríos-Llorente, A | 1 |
Sanchez-Barrado, E | 1 |
Muñoz-Bellvís, L | 1 |
Aldecoa, C | 1 |
Bermejo-Martin, JF | 1 |
Martín-Rodríguez, F | 2 |
López-Izquierdo, R | 2 |
Medina-Lozano, E | 1 |
Ortega Rabbione, G | 1 |
Del Pozo Vegas, C | 2 |
Carbajosa Rodríguez, V | 1 |
Castro Villamor, MÁ | 2 |
Sánchez-Soberon, I | 1 |
Sanz-García, A | 1 |
Xu, J | 1 |
Jakher, Y | 1 |
Ahrens-Nicklas, RC | 1 |
Juaristi, I | 1 |
García-Martín, ML | 1 |
Rodrigues, TB | 1 |
Satrústegui, J | 1 |
Llorente-Folch, I | 1 |
Pardo, B | 1 |
Horvat, A | 1 |
Vardjan, N | 1 |
Zorec, R | 1 |
Adler, C | 1 |
Paul, C | 1 |
Hinkelbein, J | 1 |
Michels, G | 1 |
Pfister, R | 1 |
Krings, A | 1 |
Lechleuthner, A | 1 |
Stangl, R | 1 |
Jovandaric, MZ | 1 |
Milenkovic, SJ | 1 |
Zhou, BC | 1 |
Zhang, Z | 1 |
Zhu, JJ | 1 |
Liu, LJ | 1 |
Liu, CF | 1 |
Mangas, IM | 1 |
Del Brío Ibáñez, P | 1 |
Delgado Benito, JF | 1 |
Martín Conty, JL | 1 |
Manzanares, JÁ | 1 |
Mayo-Iscar, A | 1 |
Das, BP | 1 |
Sharma, M | 1 |
Bansal, S | 1 |
Philip, M | 1 |
Umamaheswara Rao, GS | 1 |
Kaji, AH | 1 |
Hanif, AM | 1 |
Bosson, N | 1 |
Ostermayer, D | 1 |
Niemann, JT | 1 |
Arveladze, GA | 1 |
Geladze, NM | 1 |
Sanikidze, TB | 1 |
Khachapuridze, NS | 1 |
Bakhtadze, SZ | 1 |
Brallier, JW | 1 |
Dalal, PJ | 1 |
McCormick, PJ | 1 |
Deiner, SG | 1 |
Horosh, M | 1 |
Feldman, H | 1 |
Yablonovich, A | 1 |
Firer, MA | 1 |
Abookasis, D | 1 |
Hifumi, T | 1 |
Kawakita, K | 1 |
Yoda, T | 1 |
Okazaki, T | 1 |
Kuroda, Y | 1 |
de Almeida, SM | 1 |
Faria, FL | 1 |
de Goes Fontes, K | 1 |
Buczenko, GM | 1 |
Berto, DB | 1 |
Raboni, SM | 1 |
Vidal, LR | 1 |
Nogueira, MB | 1 |
Wang, Q | 1 |
van Hoecke, M | 1 |
Tang, XN | 1 |
Lee, H | 1 |
Zheng, Z | 1 |
Swanson, RA | 1 |
Yenari, MA | 1 |
Bhargava, D | 1 |
Al-Tamimi, Y | 1 |
Quinn, A | 1 |
Ross, S | 1 |
Chen, H | 1 |
Spagnoli, F | 1 |
Burris, M | 1 |
Rolland, WB | 1 |
Fajilan, A | 1 |
Dou, H | 1 |
Tang, J | 1 |
Zhang, JH | 1 |
Alves, RL | 1 |
Aragão e Silva, AL | 1 |
Kraychete, NC | 1 |
Campos, GO | 1 |
Martins, Mde J | 1 |
Módolo, NS | 1 |
Mackie, AS | 1 |
Alton, GY | 1 |
Dinu, IA | 1 |
Joffe, AR | 1 |
Roth, SJ | 1 |
Newburger, JW | 1 |
Robertson, CM | 1 |
Stadlbauer, KH | 1 |
Wagner-Berger, HG | 1 |
Wenzel, V | 1 |
Voelckel, WG | 1 |
Krismer, AC | 1 |
Klima, GCDN | 1 |
Rheinberger, K | 1 |
Pechlaner, S | 1 |
Mayr, VD | 1 |
Lindner, KH | 1 |
Kliegel, A | 1 |
Losert, H | 1 |
Sterz, F | 1 |
Holzer, M | 1 |
Zeiner, A | 1 |
Havel, C | 1 |
Laggner, AN | 1 |
Finsterer, J | 2 |
Milvay, E | 2 |
Cengiz, SL | 1 |
Ak, A | 1 |
Ustün, ME | 1 |
Karaköse, S | 1 |
Zupan Simunek, V | 1 |
Jaeger, A | 1 |
Kopferschmitt, J | 1 |
Sauder, P | 1 |
Benmatti, A | 1 |
Mantz, JM | 1 |
Pach, J | 1 |
Kamenczak, A | 1 |
Panas, M | 1 |
Anderson, YS | 1 |
Curtis, NJ | 1 |
Hobbs, JA | 1 |
Thompson, CH | 1 |
Winearls, CG | 1 |
Radda, GK | 1 |
Clarke, K | 1 |
Altmann, P | 1 |
Carlini, SM | 1 |
Beyers, N | 1 |
Schoeman, JF | 1 |
Nel, ED | 1 |
Truter, EJ | 1 |
Donald, PR | 1 |
Obermann, I | 1 |
Liu, XL | 1 |
Nozari, A | 1 |
Basu, S | 1 |
Ronquist, G | 1 |
Rubertsson, S | 1 |
Wiklund, L | 1 |
Russell, JL | 1 |
Kushner, MG | 1 |
Beitman, BD | 1 |
Bartels, KM | 1 |
Stansbie, D | 1 |
Wallace, SJ | 1 |
Marsac, C | 1 |
Vaagenes, P | 1 |
Kjekshus, J | 1 |
Sivertsen, E | 1 |
Semb, G | 1 |
Mock, DM | 1 |
Baswell, DL | 1 |
Baker, H | 1 |
Holman, RT | 1 |
Sweetman, L | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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Evaluation of the Heart's Respiratory Quotient as Predictive Value After Extra-hospital[NCT04211207] | 40 participants (Actual) | Observational | 2020-01-27 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
7 reviews available for lactic acid and Nervous System Disorders
Article | Year |
---|---|
Metabolic Transporters in the Peripheral Nerve-What, Where, and Why?
Topics: Animals; Glucose; Lactic Acid; Monocarboxylic Acid Transporters; Nervous System Diseases; Peripheral | 2021 |
Predictors of survival for pediatric extracorporeal cardiopulmonary resuscitation: A systematic review and meta-analysis.
Topics: Cardiopulmonary Resuscitation; Child; Creatinine; Humans; Lactic Acid; Nervous System Diseases; Oxyg | 2022 |
Brain Branched-Chain Amino Acids in Maple Syrup Urine Disease: Implications for Neurological Disorders.
Topics: Amino Acids, Branched-Chain; Aspartic Acid; Brain; Central Nervous System; Disease Susceptibility; G | 2020 |
Targeting Astrocytes for Treating Neurological Disorders: Carbon Monoxide and Noradrenaline-Induced Increase in Lactate.
Topics: Animals; Astrocytes; Carbon Monoxide; Drug Delivery Systems; Humans; Lactic Acid; Nervous System Dis | 2017 |
Blood Lactate or Lactate Clearance: Which Is Robust to Predict the Neurological Outcomes after Cardiac Arrest? A Systematic Review and Meta-Analysis.
Topics: Biomarkers; Heart Arrest; Humans; Lactic Acid; Metabolic Clearance Rate; Nervous System Diseases | 2018 |
[Definition of intrapartum asphyxia and effects on outcome].
Topics: Acidosis; Apgar Score; Biomarkers; Brain Diseases; Cerebral Palsy; Female; Fetal Blood; Fetal Hypoxi | 2008 |
Disorders of the pyruvate dehydrogenase complex.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acidosis; Brain; Carbon Dioxide; Child; Child, Preschool; Coe | 1986 |
35 other studies available for lactic acid and Nervous System Disorders
Article | Year |
---|---|
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
Topics: Adult; Blood-Brain Barrier; Cerebrospinal Fluid Proteins; COVID-19; Cytokines; Europe; Female; Human | 2022 |
[Correlation between four limbs perfusion index and lactic acid in patients with severe neurological diseases].
Topics: Adult; Aged; Area Under Curve; Female; Humans; Lactic Acid; Lower Extremity; Male; Microcirculation; | 2023 |
Serum lactate level upon admission to the neuro-intensive care unit and 90-day mortality: A retrospective study.
Topics: Adult; Aged; Area Under Curve; Critical Illness; Female; Hospital Mortality; Humans; Intensive Care | 2019 |
Clinical impact of intraoperative hyperlactatemia during craniotomy.
Topics: Cohort Studies; Craniotomy; Female; Humans; Hyperlactatemia; Intraoperative Complications; Lactic Ac | 2019 |
MR- proADM to detect specific types of organ failure in infection.
Topics: Adrenomedullin; Aged; Aged, 80 and over; Area Under Curve; Blood Coagulation Disorders; C-Reactive P | 2020 |
Accuracy of prehospital point-of-care lactate in early in-hospital mortality.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulances; Area Under Curve; Cardiovascular Diseases; E | 2020 |
ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate.
Topics: Aggrecans; Amino Acid Transport Systems, Acidic; Animals; Antiporters; Astrocytes; Brain Chemistry; | 2017 |
[Which patients benefit from transport with ongoing cardiopulmonary resuscitation? : Retrospective analysis of 70 patients with refractory preclinical cardiac arrest].
Topics: Adult; Aged; Aged, 80 and over; Cardiopulmonary Resuscitation; Female; Germany; Glasgow Outcome Scal | 2018 |
Neurological impairments in hypoxic neonates and lactate levels.
Topics: Acidosis; Age Factors; Blood Gas Analysis; Female; Gestational Age; Humans; Hypoxia; Infant, Newborn | 2018 |
Prognostic value of lactate in prehospital care as a predictor of early mortality.
Topics: Aged; Aged, 80 and over; Area Under Curve; Cardiovascular Diseases; Critical Illness; Emergency Medi | 2019 |
Prognostic Value of Tissue Oxygen Monitoring and Regional Cerebral Oxygen Saturation Monitoring and Their Correlation in Neurological Patients with Sepsis: A Preliminary, Prospective, Observational Study.
Topics: Adult; Aged; APACHE; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Hospital Mortality; Humans; | 2020 |
Predictors of neurologic outcome in patients resuscitated from out-of-hospital cardiac arrest using classification and regression tree analysis.
Topics: Aged; California; Cardiopulmonary Resuscitation; Dose-Response Relationship, Drug; Epinephrine; Fema | 2014 |
[The role of lactate acidosis in the development and treatment of various neurologic syndromes in children and adolescents].
Topics: Acidosis; Adolescent; Child; Child, Preschool; Electroencephalography; Energy Metabolism; Epilepsy; | 2015 |
Elevated Intraoperative Serum Lactate During Craniotomy Is Associated With New Neurological Deficit and Longer Length of Stay.
Topics: Acute Kidney Injury; Adult; Aged; Cerebrovascular Circulation; Cohort Studies; Craniotomy; Female; H | 2017 |
Broadband Infrared Spectroscopy for Non-Contact Measurement of Neurological Disease Biomarkers in Cerebrospinal Fluid.
Topics: Albumins; Biomarkers; Humans; Lactic Acid; Nervous System Diseases; Spectrophotometry, Infrared; Spi | 2017 |
Association of brain metabolites with blood lactate and glucose levels with respect to neurological outcomes after out-of-hospital cardiac arrest: A preliminary microdialysis study.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain; Cerebrovascular Circulation; Female; Humans; Hypother | 2017 |
Quantitation of cerebrospinal fluid lactic acid in infectious and non-infectious neurological diseases.
Topics: Adult; Biomarkers; Cerebrospinal Fluid; Diagnosis, Differential; Female; Humans; Lactic Acid; Leukoc | 2009 |
Pyruvate protects against experimental stroke via an anti-inflammatory mechanism.
Topics: Animals; Body Weight; Cell Count; Disease Models, Animal; Ectodysplasins; Encephalitis; Infarction, | 2009 |
New modalities to assess efficacy of triple-h therapy: early experience.
Topics: Blood Pressure; Blood Volume; Cerebrovascular Circulation; Hemodilution; Humans; Hypoxia-Ischemia, B | 2011 |
Nanoerythropoietin is 10-times more effective than regular erythropoietin in neuroprotection in a neonatal rat model of hypoxia and ischemia.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Erythropoietin; Ex | 2012 |
Intraoperative lactate levels and postoperative complications of pediatric cardiac surgery.
Topics: Adolescent; Blood Gas Analysis; Blood Volume; Cardiac Surgical Procedures; Cardiopulmonary Bypass; C | 2012 |
Clinical outcome score predicts the need for neurodevelopmental intervention after infant heart surgery.
Topics: Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Chi-Square Dist | 2013 |
Survival with full neurologic recovery after prolonged cardiopulmonary resuscitation with a combination of vasopressin and epinephrine in pigs.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Weight; Cardiopulmonary Resuscitation; Drug Combin | 2003 |
Serial lactate determinations for prediction of outcome after cardiac arrest.
Topics: Age Factors; Aged; Biomarkers; Electrocardiography; Emergency Medical Services; Female; Follow-Up St | 2004 |
Stress lactate in mitochondrial myopathy under constant, unadjusted workload.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cohort Studies; Ergometry; Exercise Test; F | 2004 |
Lactate contents from cerebrospinal fluid in experimental subarachnoid hemorrhage, well correlate with vasospasm: ongoing and neurologic status.
Topics: Animals; Basilar Artery; Biomarkers; Cisterna Magna; Disease Models, Animal; Lactic Acid; Male; Nerv | 2007 |
[Acute nadoxolol poisoning. A multicentric study of 35 cases].
Topics: Acute Disease; Adolescent; Adult; Aged; Cardiovascular Diseases; Child, Preschool; Dopamine; Electro | 1982 |
The frequency of toxic methemoglobinemias in people living in the vicinity of refuse dumps in Barycz.
Topics: Adolescent; Adult; Aged; Air Pollutants; Environmental Monitoring; Epidemiological Monitoring; Femal | 1996 |
High serum D-lactate in patients on continuous ambulatory peritoneal dialysis.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Dialysis Solutions; Female; Humans; Kidney Fai | 1997 |
Adenylate kinase activity in the cerebrospinal fluid of children with tuberculous meningitis and its relationship to neurological outcome.
Topics: Adenylate Kinase; Adolescent; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combinat | 1997 |
Diagnostic yield of the lactate stress test in 160 patients with suspected respiratory chain disorder.
Topics: Adolescent; Adult; Aged; Electron Transport; Exercise; Exercise Test; Female; Humans; Lactic Acid; M | 2000 |
Neurological outcome after experimental cardiopulmonary resuscitation: a result of delayed and potentially treatable neuronal injury?
Topics: Angioplasty, Balloon, Coronary; Animals; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; | 2002 |
Nonfearful panic disorder in neurology patients validated by lactate challenge.
Topics: Adult; Anxiety Disorders; Fear; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Lactates; | 1991 |
Temporal pattern of enzyme changes in cerebrospinal fluid in patients with neurologic complications after open heart surgery.
Topics: Aged; Aspartate Aminotransferases; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Creatine Kin | 1987 |
Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic repercussions, and treatment.
Topics: Alopecia; Biotin; Citrates; Diagnosis, Differential; Erythema; Fatty Acids, Essential; Female; Glyci | 1985 |