lactic acid has been researched along with Neoplasms, Squamous Cell in 5 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Neoplasms, Squamous Cell: Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors." | 5.37 | Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011) |
| "A high lactate content in malignant head and neck cancer (Head and neck squamous cell carcinomas, HNSCC) is associated with a higher risk of metastatic spread and lower overall patient survival." | 1.37 | Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue. ( Kunkel, M; Mueller-Klieser, W; Reichert, TE; Wagner, W; Walenta, S; Ziebart, T, 2011) |
| "A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors." | 1.37 | Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Updegraff, BL | 1 |
| Zhou, X | 1 |
| Guo, Y | 1 |
| Padanad, MS | 1 |
| Chen, PH | 1 |
| Yang, C | 1 |
| Sudderth, J | 1 |
| Rodriguez-Tirado, C | 1 |
| Girard, L | 1 |
| Minna, JD | 1 |
| Mishra, P | 1 |
| DeBerardinis, RJ | 1 |
| O'Donnell, KA | 1 |
| Ziebart, T | 1 |
| Walenta, S | 2 |
| Kunkel, M | 1 |
| Reichert, TE | 1 |
| Wagner, W | 1 |
| Mueller-Klieser, W | 2 |
| Sandulache, VC | 1 |
| Ow, TJ | 1 |
| Pickering, CR | 1 |
| Frederick, MJ | 1 |
| Zhou, G | 1 |
| Fokt, I | 1 |
| Davis-Malesevich, M | 1 |
| Priebe, W | 1 |
| Myers, JN | 1 |
| Sattler, UG | 1 |
| Zhou, S | 1 |
| Kachhap, S | 1 |
| Sun, W | 1 |
| Wu, G | 1 |
| Chuang, A | 1 |
| Poeta, L | 1 |
| Grumbine, L | 1 |
| Mithani, SK | 1 |
| Chatterjee, A | 1 |
| Koch, W | 1 |
| Westra, WH | 1 |
| Maitra, A | 1 |
| Glazer, C | 1 |
| Carducci, M | 1 |
| Sidransky, D | 1 |
| McFate, T | 1 |
| Verma, A | 1 |
| Califano, JA | 1 |
5 other studies available for lactic acid and Neoplasms, Squamous Cell
| Article | Year |
|---|---|
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.
Topics: Basigin; Biological Transport; Carcinogenesis; Cell Line, Tumor; Cell Membrane; Cell Proliferation; | 2018 |
Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Blotting, Western; Carcin | 2011 |
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Prol | 2011 |
A bioluminescence technique for quantitative and structure-associated imaging of pyruvate.
Topics: Biological Assay; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Diagnostic Imaging; Froze | 2007 |
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
Topics: DNA, Mitochondrial; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; HeLa Cells; Hum | 2007 |