Page last updated: 2024-10-17

lactic acid and Necrosis

lactic acid has been researched along with Necrosis in 107 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" Correlation of findings with duration of hepatic pedicle clamping, postoperative markers of hepatocellular necrosis and function (aminotransferases, arterial lactate, international normalized ratio, bilirubin), and morbidity."3.83Mitochondrial bioenergetics and posthepatectomy liver dysfunction. ( Alexandrino, H; Castro E Sousa, F; Martins, MA; Palmeira, CM; Rolo, AP; Teodoro, JS; Tralhão, JG; Varela, AT, 2016)
" d-Serine injures the rat kidney, causing selective necrosis of the proximal straight tubules."3.721H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects. ( Jacobsen, M; Lock, EA; Williams, RE, 2003)
" Treatment with 1,9-dideoxyforskolin (ddFSK), an inactive analogue of the adenylate cyclase activator forskolin, induces necrotic cell death and switches to necrosis the response to the apoptosis inducers in Jurkat and in other cell models."3.72Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)- and PKB/AKT-independent fashion. ( Battaglia, M; Bernardi, P; Fassetta, M; Gentile, A; Gramaglia, D; Petronilli, V; Ranzato, L; Rasola, A, 2004)
" A 24-h incubation of PC12 cells with NO donors (SNAP or NOC-18) or specific inhibitors of mitochondrial respiration (myxothiazol, rotenone, or azide), in the absence of glucose, caused total ATP depletion and resulted in 80-100% necrosis."3.70Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. ( Bal-Price, A; Brown, GC, 2000)
"We have examined the effect of L- and D-2-chloropropionic acid (L-CPA and D-CPA) on the concentrations of pyruvate, lactate, glucose and beta-hydroxybutyrate in the blood at various times after doses which produce cerebellar granule cell necrosis."3.69Chloropropionic acid-induced alterations in glucose metabolic status: possible relevance to cerebellar granule cell necrosis. ( Gyte, A; Lock, EA; Simpson, M; Widdowson, P; Wyatt, I, 1995)
"Aluminum lactate, injected in rats, produced skeletal muscle necrosis of diaphragm and abdominal wall subjacent to peritoneal surfaces."3.68Parenteral aluminum compounds produce a local toxic myopathy in rats: importance of the anion. ( Drakontides, AB; Levine, S; Saltzman, A, 1992)
"route, in various types of cancer disease such as non-small cell lung cancer and advanced breast cancer."2.67Experimental studies and preliminary clinical trial of vinorelbine-loaded polymeric bioresorbable implants for the local treatment of solid tumors. ( Bouffard, P; Caty, A; Fournier, C; Hecquet, B; Krikorian, A; Lefebvre, JL; Merle, S; Vanseymortier, L; Vert, M; Vilain, MO, 1991)
"GPR81 supports breast cancer aggressiveness, and in MCF-7 cells, this occurs at least in part via DLL4."1.91Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4. ( Blasco, LP; Dmytriyeva, O; Goncalves-Alves, E; Kveiborg, M; Lundø, K; Pedersen, SF; Ponniah, M; Sandelin, A; Schwartz, TW; Severin, M; Spøhr, L; Trauelsen, M; Yao, J, 2023)
"Benzbromarone is an uricosuric structurally related to amiodarone and a known mitochondrial toxicant."1.40Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. ( Felser, A; Jenö, P; Krähenbühl, S; Kratschmar, DV; Lindinger, PW; Mies, S; Odermatt, A; Schnell, D, 2014)
"Cervical cancer is a human papilloma virus (HPV)-related cancer, but most HPV infections are transient or intermittent and resolve spontaneously."1.39Normal and tumour cervical cells respond differently to vaginal lactobacilli, independent of pH and lactate. ( Akrami, SM; Mirsalehian, A; Modarressi, MH; Motevaseli, E; Mousavi, AS; Shirzad, M, 2013)
" This dosage form permits the prolonged drug release."1.39Evaluation of the effects of thalidomide-loaded biodegradable devices in solid Ehrlich tumor. ( Dantas Cassali, G; Ligorio Fialho, S; Maria de Souza, C; Pereira, BG; Silva-Cunha, A, 2013)
"Gastric necrosis was identified in 12 dogs at the time of surgery and in 4 dogs at necropsy."1.39Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004-2009). ( Beer, KA; Drobatz, KJ; Syring, RS, 2013)
"Horses (n=73) with >or=360 degrees volvulus of the ascending colon."1.34Plasma lactate as a predictor of colonic viability and survival after 360 degrees volvulus of the ascending colon in horses. ( Hauptman, JG; Holcombe, SJ; Johnston, K, 2007)
" This study addresses the essential role of dosage in studies using C1-INH."1.31Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects. ( Berg, O; Bhakdi, S; Bierbach, B; Darius, H; Götze, O; Hafner, G; Heimann, A; Horstick, G; Horstick, M; Kempski, O; Loos, M; Meyer, J; Petersen, S, 2001)
"Gastric necrosis was identified in 38 (37%) dogs."1.30Plasma lactate concentration as a predictor of gastric necrosis and survival among dogs with gastric dilatation-volvulus: 102 cases (1995-1998). ( de Papp, E; Drobatz, KJ; Hughes, D, 1999)
"Fifteen consecutive patients with septic shock and six mechanically ventilated patients without septic shock."1.30Myocardial cell injury in septic shock. ( Bellomo, R; Tsamitros, M; Turner, A, 1999)
"Necrosis was present histologically in four of the five meningiomas classified either as atypical or papillary."1.30Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy. ( Handa, J; Inubushi, T; Matsuda, M; Morikawa, S; Nakasu, S; Shino, A, 1999)

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-199010 (9.35)18.7374
1990's15 (14.02)18.2507
2000's40 (37.38)29.6817
2010's39 (36.45)24.3611
2020's3 (2.80)2.80

Authors

AuthorsStudies
Lundø, K1
Dmytriyeva, O1
Spøhr, L1
Goncalves-Alves, E1
Yao, J1
Blasco, LP1
Trauelsen, M1
Ponniah, M1
Severin, M1
Sandelin, A1
Kveiborg, M1
Schwartz, TW1
Pedersen, SF1
Shu, W1
Wan, J1
Chen, J1
He, W1
Zhu, Y2
Zeng, H1
Liu, P1
Xia, L1
Lu, N1
Rauserova-Lexmaulova, L1
Vanova-Uhrikova, I1
Rehakova, K1
Hazem, SH1
Hamed, MF1
Saad, MA1
Gameil, NM1
Murakami, T2
Sato, Y2
Sato, A2
Mukai, S2
Kobayashi, M2
Yamada, Y2
Kawakami, E2
Motevaseli, E1
Shirzad, M1
Akrami, SM1
Mousavi, AS1
Mirsalehian, A1
Modarressi, MH1
Landry, GM1
Dunning, CL1
Conrad, T1
Hitt, MJ1
McMartin, KE1
Schwartz, S1
Kightlinger, E1
de Virgilio, C1
de Virgilio, M1
Kaji, A1
Neville, A1
Bennion, R1
Saltzman, DJ1
Coskun, C1
Avci, B1
Yalcin, M1
Yermezler, A1
Yilmaz, MS1
Savci, V1
Riddle, A1
Maire, J1
Cai, V1
Nguyen, T1
Gong, X1
Hansen, K1
Grafe, MR1
Hohimer, AR1
Back, SA1
El Sayed, SM1
Mohamed, WG1
Seddik, MA1
Ahmed, AS1
Mahmoud, AG1
Amer, WH1
Helmy Nabo, MM1
Hamed, AR1
Ahmed, NS1
Abd-Allah, AA1
Chen, G1
Liu, T1
Felser, A1
Lindinger, PW1
Schnell, D1
Kratschmar, DV1
Odermatt, A1
Mies, S1
Jenö, P1
Krähenbühl, S1
Chen, Y1
Jiang, L1
Wang, R1
Lu, M1
Zhang, Q1
Zhou, Y1
Wang, Z1
Lu, G1
Liang, P1
Ran, H1
Chen, H1
Zheng, Y1
Yuan, Z1
Zhao, X1
Wang, X1
Qiu, W1
Chen, X1
Zheng, Q1
Cui, W1
Kolesnik, DL1
Pyaskovskaya, ON1
Boichuk, IV1
Solyanik, GI1
Porcelli, L1
Guida, G1
Quatrale, AE1
Cocco, T1
Sidella, L1
Maida, I1
Iacobazzi, RM1
Ferretta, A1
Stolfa, DA1
Strippoli, S1
Guida, S1
Tommasi, S1
Guida, M1
Azzariti, A1
Bhang, SH1
Han, J1
Jang, HK1
Noh, MK1
La, WG1
Yi, M1
Kim, WS1
Kwon, YK1
Yu, T1
Kim, BS1
Sheibani, S1
Jones, NK1
Eid, R1
Gharib, N1
Arab, NT1
Titorenko, V1
Vali, H1
Young, PA1
Greenwood, MT1
Alexandrino, H1
Varela, AT1
Teodoro, JS1
Martins, MA1
Rolo, AP1
Tralhão, JG1
Palmeira, CM1
Castro E Sousa, F1
Haldenwang, PL1
Häuser, L1
Prochnow, N1
Ziebura, D1
Baumann, A1
Sikole, M1
Schlömicher, M1
Schmitz, I1
Christ, H1
Strauch, JT1
Wu, SB1
Rodgers, NJ1
Cui, G1
Sun, Y1
Choct, M1
Faria, J1
Barbosa, J1
Queirós, O1
Moreira, R1
Carvalho, F1
Dinis-Oliveira, RJ1
Ben-Arie, G1
Serlin, Y1
Ivens, S1
Benifla, M1
Cagnano, E1
Melamed, I1
Merkin, V1
Shelef, I1
Nakao, S1
Nakada, S1
Nuzzo, A1
Maggiori, L1
Ronot, M1
Becq, A1
Plessier, A1
Gault, N1
Joly, F1
Castier, Y1
Vilgrain, V1
Paugam, C1
Panis, Y1
Bouhnik, Y1
Cazals-Hatem, D1
Corcos, O1
Cohen, JL1
Stekelenburg, A1
Gawlitta, D1
Bader, DL1
Oomens, CW1
Gharapetian, A1
Holmes, DT1
Urquhart, N1
Rosenberg, F1
Piao, L1
Li, Y1
Kim, SJ1
Byun, HS1
Huang, SM1
Hwang, SK1
Yang, KJ1
Park, KA1
Won, M1
Hong, J1
Hur, GM1
Seok, JH1
Shong, M1
Cho, MH1
Brazil, DP1
Hemmings, BA1
Park, J1
Nakajima, T1
Kumabe, T1
Kanamori, M1
Saito, R1
Tashiro, M1
Watanabe, M1
Tominaga, T1
Bertuzzi, A1
Fasano, A1
Gandolfi, A1
Sinisgalli, C1
Stringfellow, K1
McReynolds, J1
Lee, J1
Byrd, J1
Nisbet, D1
Farnell, M1
Karu, I2
Tähepõld, P1
Sulling, TA1
Alver, M1
Zilmer, M2
Starkopf, J2
Saxena, S2
Shukla, D1
Khan, YA1
Singh, M1
Bansal, A1
Sairam, M1
Jain, SK1
Pajek, J1
Kveder, R1
Gucek, A1
Skoberne, A1
Bren, A1
Bucar, M1
Cerne, D1
Lukac-Bajalo, J1
Patel, RB1
Solorio, L1
Wu, H1
Krupka, T1
Exner, AA1
Matoba, M1
Kondou, T1
Tanaka, T1
Kitadate, M1
Oota, K1
Tonami, H1
Green, TI1
Tonozzi, CC1
Kirby, R1
Rudloff, E1
Yaligar, J1
Thakur, SB1
Bokacheva, L1
Carlin, S1
Thaler, HT1
Rizwan, A1
Lupu, ME1
Wang, Y1
Matei, CC1
Zakian, KL1
Koutcher, JA1
Nukada, Y1
Ito, Y1
Miyazawa, M1
Sakaguchi, H1
Nishiyama, N1
Colen, CB1
Shen, Y1
Ghoddoussi, F1
Yu, P1
Francis, TB1
Koch, BJ1
Monterey, MD1
Galloway, MP1
Sloan, AE1
Mathupala, SP1
Mauro, C1
Leow, SC1
Anso, E1
Rocha, S1
Thotakura, AK1
Tornatore, L1
Moretti, M1
De Smaele, E1
Beg, AA1
Tergaonkar, V1
Chandel, NS1
Franzoso, G1
Vermeulen Windsant, IC1
Hellenthal, FA1
Derikx, JP1
Prins, MH1
Buurman, WA1
Jacobs, MJ1
Schurink, GW1
Bustamante-Marín, X1
Quiroga, C1
Lavandero, S1
Reyes, JG1
Moreno, RD1
Jeevitha, D1
Amarnath, K1
Anada, T1
Fukuda, J1
Sai, Y1
Suzuki, O1
Pereira, BG1
Ligorio Fialho, S1
Maria de Souza, C1
Dantas Cassali, G1
Silva-Cunha, A1
Beer, KA1
Syring, RS1
Drobatz, KJ2
Allen, NJ1
Attwell, D1
Rock, JP1
Hearshen, D1
Scarpace, L1
Croteau, D1
Gutierrez, J1
Fisher, JL1
Rosenblum, ML1
Mikkelsen, T1
Pomorski, L1
Bartos, M1
Matejkowska, M1
Kuzdak, K1
Jordan, DR1
Brownstein, S1
Gilberg, S1
Matthew, B1
Mawn, L1
Khouri, L1
Iwasaki, Y1
Tagaya, N1
Hattori, Y1
Yamaguchi, K1
Kubota, K1
Southworth, R1
Garlick, PB1
Wilson, JS1
Rushing, G1
Johnson, BL1
Kline, JA1
Parker, JL1
Bowser, A1
Bandyk, DF1
Back, MR1
Zoula, S1
Hérigault, G1
Ziegler, A1
Farion, R1
Décorps, M1
Rémy, C1
Williams, RE1
Jacobsen, M1
Lock, EA2
Gramaglia, D1
Gentile, A1
Battaglia, M1
Ranzato, L1
Petronilli, V1
Fassetta, M1
Bernardi, P1
Rasola, A1
Herynek, V1
Burian, M1
Jirák, D1
Liscák, R1
Námestková, K1
Hájek, M1
Syková, E1
Ramonet, D1
Rodríguez, MJ1
Fredriksson, K1
Bernal, F1
Mahy, N1
Yousefi, S1
Owens, JW1
Cesario, TC1
Godfried, MH1
Boer, K1
Beuger, S1
Scherpbier, HJ1
Kuijpers, TW1
Suzuki, M1
Koike, T1
Loit, R1
Paapstel, A1
Kairane, C1
Qiao, T1
Liu, C1
Ran, F1
Radad, K1
Rausch, WD1
Gille, G2
Hamann, J1
Rommelspacher, H1
Storch, A1
Reichmann, H1
Johnston, K1
Holcombe, SJ1
Hauptman, JG1
Zhong, Y1
Zhang, L1
Ding, AG1
Shenderova, A1
Zhu, G1
Pei, P1
Chen, RR1
Mallery, SR1
Mooney, DJ1
Schwendeman, SP1
Davison, SP1
Timpone, J1
Hannan, CM1
Karagulle Kendi, AT1
Krenzel, C1
Ott, FW1
Brace, JR1
Norberg, SK1
Kieffer, SA1
Young, RS1
Yagel, SK1
Towfighi, J1
Trifillis, AL1
Kahng, MW1
Trump, BF1
Hansen, TL1
Christensen, E1
Brandt, NJ1
Gutiérrez, JM2
Romero, M1
Núñez, J2
Chaves, F1
Borkow, G1
Ovadia, M1
Schwickert, G1
Walenta, S1
Sundfør, K1
Rofstad, EK1
Mueller-Klieser, W1
Gyte, A1
Widdowson, P1
Simpson, M1
Wyatt, I1
Horstick, G2
Heimann, A2
Götze, O2
Hafner, G2
Berg, O2
Böhmer, P1
Becker, P1
Darius, H2
Rupprecht, HJ1
Loos, M2
Bhakdi, S2
Meyer, J3
Kempski, O2
de Jonge, R1
Bradamante, S1
Speleman, L1
Willem de Jong, J1
Vicente Villa, MA1
Rueda Muñoz, A1
González-Enseñat, MA1
Corretger Rauet, J1
Medina, M1
Palou Aymerich, J1
Plum, J2
Lordnejad, MR1
Grabensee, B2
Mehmet, H1
Yue, X1
Penrice, J1
Cady, E1
Wyatt, JC1
Sarraf, C1
Squier, M1
Edwards, AD1
de Papp, E1
Hughes, D1
Turner, A1
Tsamitros, M1
Bellomo, R1
Shino, A1
Nakasu, S1
Matsuda, M1
Handa, J1
Morikawa, S1
Inubushi, T1
Gocan, NC1
Scott, JA1
Tyml, K1
Harada, M1
Hisaoka, S1
Mori, K1
Yoneda, K1
Noda, S1
Nishitani, H1
Bal-Price, A2
Brown, GC2
Son, BC1
Kim, MC1
Choi, BG1
Kim, EN1
Baik, HM1
Choe, BY1
Naruse, S1
Kang, JK1
Lopes-Ferreira, M1
Rucavado, A1
Farsky, SH1
Lomonte, B1
Angulo, Y1
Moura Da Silva, AM1
Eriskat, J1
Stoffel, M1
Plesnila, N1
Rinecker, M1
Baethmann, A1
Razeghi, P1
Lordnejad, RM1
Perniok, A1
Fleisch, M1
Fusshöller, A1
Schneider, M1
Bierbach, B1
Petersen, S1
Horstick, M1
Vogt, AM1
Ackermann, C1
Yildiz, M1
Schoels, W1
Kübler, W1
Levine, S1
Saltzman, A1
Drakontides, AB1
Bernsen, HJ1
Heerschap, A1
van der Kogel, AJ1
van Vaals, JJ1
Prick, MJ1
Poels, EF1
Grotenhuis, JA1
Rubin, BB1
Liauw, S1
Tittley, J1
Romaschin, AD1
Walker, PM1
Fournier, C1
Hecquet, B1
Bouffard, P1
Vert, M1
Caty, A1
Vilain, MO1
Vanseymortier, L1
Merle, S1
Krikorian, A1
Lefebvre, JL1
Brody, HJ1
Sochor, H1
Gaba, DM1
Maxwell, MS1
Merlone, S1
Smith, C1
Nutz, V1
Sommer, JH1
Schultze-Petzold, J1
Nuzhnyĭ, VP1
Tezikov, EB1
Savitskaia, EV1
Ugriumov, AI1
Ingvar, M1
Folbegrova, J1
Siesjö, BK1
Kao, RL1
Magovern, GJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
6 Month Double-Blind Randomized Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Small Particle Hyaluronic Acid to Treat Acne Scars Located on the Cheeks and Forehead[NCT02955381]26 participants (Actual)Interventional2017-03-28Terminated (stopped due to Liquidation of Research Department)
Energy MEtabolism of Septic Heart.[NCT05202938]32 participants (Anticipated)Observational2022-07-21Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for lactic acid and Necrosis

ArticleYear
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study.
    Chinese journal of cancer, 2014, Volume: 33, Issue:7

    Topics: Acetaminophen; Adult; Carcinoma, Hepatocellular; Disease Progression; Drug Therapy, Combination; Enz

2014
Understanding, avoiding, and managing dermal filler complications.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2008, Volume: 34 Suppl 1

    Topics: Animals; Biocompatible Materials; Cattle; Collagen; Cosmetic Techniques; Durapatite; Female; Foreign

2008
Deep tissue injury: how deep is our understanding?
    Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:7

    Topics: Animals; Apoptosis; Biomechanical Phenomena; Blood Glucose; Cell Survival; Humans; Ischemia; Lactic

2008
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:2

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates;

1992

Trials

5 trials available for lactic acid and Necrosis

ArticleYear
[Therapeutic evaluation of the polylactic acid gel (PLA-G) used for preventing skin flap adhesion in modified radical mastectomy].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2013, Volume: 30, Issue:6

    Topics: Breast Neoplasms; Drainage; Female; Gels; Humans; Lactic Acid; Mastectomy, Modified Radical; Necrosi

2013
Effect of bismuth citrate, lactose, and organic acid on necrotic enteritis in broilers.
    Poultry science, 2009, Volume: 88, Issue:11

    Topics: Animals; Chickens; Citric Acid; Clostridium Infections; Clostridium perfringens; Drug Therapy, Combi

2009
Cell-free DNA in the peritoneal effluent of peritoneal dialysis solutions.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2010, Volume: 14, Issue:1

    Topics: Apoptosis; Ascitic Fluid; Bicarbonates; Biomarkers; Buffers; Cell-Free System; Cross-Over Studies; D

2010
Circulating intestinal fatty acid-binding protein as an early marker of intestinal necrosis after aortic surgery: a prospective observational cohort study.
    Annals of surgery, 2012, Volume: 255, Issue:4

    Topics: Aged; Aortic Aneurysm; Arteries; Biomarkers; Endovascular Procedures; Fatty Acid-Binding Proteins; F

2012
Experimental studies and preliminary clinical trial of vinorelbine-loaded polymeric bioresorbable implants for the local treatment of solid tumors.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Adult; Animals; Antineoplastic Agents; Delayed-Action Preparations; Dogs; Dose-Response Relationship

1991

Other Studies

98 other studies available for lactic acid and Necrosis

ArticleYear
Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4.
    BMC cancer, 2023, Nov-22, Volume: 23, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; Calcium-Binding Proteins; Female; Humans; La

2023
Initially elevated arterial lactate as an independent predictor of poor outcomes in severe acute pancreatitis.
    BMC gastroenterology, 2020, Apr-19, Volume: 20, Issue:1

    Topics: Adult; Aged; Arteries; Female; Humans; Intra-Abdominal Hypertension; Lactic Acid; Male; Middle Aged;

2020
Acid-Base, Electrolyte and Lactate Abnormalities as Well as Gastric Necrosis and Survival in Dogs With Gastric Dilation-Volvulus Syndrome. A Retrospective Study in 75 Dogs.
    Topics in companion animal medicine, 2020, Volume: 39

    Topics: Animals; Czech Republic; Dog Diseases; Dogs; Electrolytes; Female; Gastric Dilatation; Hydrogen-Ion

2020
Comparison of lactate and β-hydroxybutyrate in the treatment of concanavalin-A induced hepatitis.
    International immunopharmacology, 2018, Volume: 61

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Inflammatory Agents; Concanavalin A; Cytokines; Drug Therapy, C

2018
Transrectal ultrasonography and blood lactate measurement: a combined diagnostic approach for severe uterine torsion in dairy cattle.
    The Journal of veterinary medical science, 2019, Oct-10, Volume: 81, Issue:9

    Topics: Animals; Cattle; Cattle Diseases; Dairying; Female; Lactic Acid; Laparotomy; Necrosis; Pregnancy; To

2019
Normal and tumour cervical cells respond differently to vaginal lactobacilli, independent of pH and lactate.
    Journal of medical microbiology, 2013, Volume: 62, Issue:Pt 7

    Topics: Apoptosis; Caspase 3; Chorionic Gonadotropin, beta Subunit, Human; Female; Gene Expression Regulatio

2013
Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death.
    Toxicology letters, 2013, Aug-29, Volume: 221, Issue:3

    Topics: Acute Kidney Injury; Cells, Cultured; Glycolates; Humans; Kidney Tubules, Proximal; Lactic Acid; Mic

2013
Predictors of mortality and limb loss in necrotizing soft tissue infections.
    The American surgeon, 2013, Volume: 79, Issue:10

    Topics: Amputation, Surgical; Biomarkers; Debridement; Decision Support Techniques; Humans; Lactic Acid; Log

2013
Protective effect of CDP-choline on ischemia-reperfusion-induced myocardial tissue injury in rats.
    Irish journal of medical science, 2014, Volume: 183, Issue:4

    Topics: Animals; Apoptosis; Arginine; Blood Pressure; Cytidine Diphosphate Choline; Homocysteine; Lactic Aci

2014
Hemodynamic and metabolic correlates of perinatal white matter injury severity.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Analysis of Variance; Animals; Blood Chemical Analysis; Blood Glucose; Blood Pressure; Brain Ischemi

2013
Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure.
    Toxicology, 2014, Oct-03, Volume: 324

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzbromarone; Chemical and Drug Induced Liver Injury; D

2014
Injectable smart phase-transformation implants for highly efficient in vivo magnetic-hyperthermia regression of tumors.
    Advanced materials (Deerfield Beach, Fla.), 2014, Nov-26, Volume: 26, Issue:44

    Topics: Ablation Techniques; Adenocarcinoma; Animals; Humans; Hyperthermia, Induced; Lactic Acid; Magnetic F

2014
Promotion of initial anti-tumor effect via polydopamine modified doxorubicin-loaded electrospun fibrous membranes.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspa

2014
Hypoxia enhances antitumor activity of dichloroacetate.
    Experimental oncology, 2014, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell

2014
Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy.
    Journal of translational medicine, 2015, Jan-27, Volume: 13

    Topics: Albumins; Apoptosis; Aurora Kinase B; Cell Line, Tumor; Cell Movement; Cell Nucleus Shape; Cell Prol

2015
pH-triggered release of manganese from MnAu nanoparticles that enables cellular neuronal differentiation without cellular toxicity.
    Biomaterials, 2015, Volume: 55

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Differentiation; Cell Membrane; Drug Delivery Syste

2015
Inhibition of stress mediated cell death by human lactate dehydrogenase B in yeast.
    FEMS yeast research, 2015, Volume: 15, Issue:5

    Topics: Apoptosis; Autophagy; bcl-2-Associated X Protein; Copper; Humans; Isoenzymes; L-Lactate Dehydrogenas

2015
Mitochondrial bioenergetics and posthepatectomy liver dysfunction.
    European journal of clinical investigation, 2016, Volume: 46, Issue:7

    Topics: Adenoma; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Ami

2016
Low-flow lower body perfusion for spinal protection in a frozen elephant trunk simulation model.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2016, Volume: 50, Issue:5

    Topics: Animals; Aorta, Thoracic; Blood Vessel Prosthesis Implantation; Cardiopulmonary Bypass; Cerebrospina

2016
Dynamics of intestinal metabolites and morphology in response to necrotic enteritis challenge in broiler chickens.
    Avian pathology : journal of the W.V.P.A, 2016, Volume: 45, Issue:3

    Topics: Animal Feed; Animals; Chickens; Clostridium Infections; Clostridium perfringens; Coccidiosis; Dietar

2016
Comparative study of the neurotoxicological effects of tramadol and tapentadol in SH-SY5Y cells.
    Toxicology, 2016, 06-01, Volume: 359-360

    Topics: Adenosine Triphosphate; Analgesics, Opioid; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; C

2016
Diagnosing necrotic meningioma: a distinctive imaging pattern in diffusion MRI and MR spectroscopy.
    The neuroradiology journal, 2017, Volume: 30, Issue:1

    Topics: Choline; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Gluta

2017
Blood lactate concentration as diagnostic predictors of uterine necrosis and its outcome in dairy cows with uterine torsion.
    The Journal of veterinary medical science, 2017, Mar-18, Volume: 79, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Cattle; Cattle Diseases; Creatine Kinase; Dairying; Female; La

2017
Predictive Factors of Intestinal Necrosis in Acute Mesenteric Ischemia: Prospective Study from an Intestinal Stroke Center.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Area Under Curve; Cohort Studies; Digesti

2017
Dehydrogenase interference with enzymatic ethanol assays: forgotten but not gone.
    Clinical chemistry, 2008, Volume: 54, Issue:7

    Topics: Acetaminophen; Ethanol; False Positive Reactions; Humans; L-Lactate Dehydrogenase; Lactic Acid; Live

2008
Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death.
    Cancer research, 2009, Apr-15, Volume: 69, Issue:8

    Topics: Adenosine Triphosphate; Calcium-Binding Proteins; Cell Death; Enzyme Activation; HeLa Cells; Humans;

2009
Differential diagnosis between radiation necrosis and glioma progression using sequential proton magnetic resonance spectroscopy and methionine positron emission tomography.
    Neurologia medico-chirurgica, 2009, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Aged; Biomarkers; Brain; Brain Neoplasms; Carbon Radioisotopes; Choline; Diagnosi

2009
Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?
    Journal of theoretical biology, 2010, Jan-07, Volume: 262, Issue:1

    Topics: Adenosine Triphosphate; Animals; Carcinoma; Dose-Response Relationship, Drug; Energy Metabolism; Fem

2010
Off-pump coronary surgery causes immediate release of myocardial damage markers.
    Asian cardiovascular & thoracic annals, 2009, Volume: 17, Issue:5

    Topics: Aged; Biomarkers; Coronary Artery Bypass, Off-Pump; Creatine Kinase, MB Form; Female; Glutathione; H

2009
Hypoxia preconditioning by cobalt chloride enhances endurance performance and protects skeletal muscles from exercise-induced oxidative damage in rats.
    Acta physiologica (Oxford, England), 2010, Volume: 200, Issue:3

    Topics: Animals; Antioxidants; Cell Hypoxia; Cobalt; Creatine Kinase, MM Form; Cytoprotection; Disease Model

2010
Effect of injection site on in situ implant formation and drug release in vivo.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Nov-01, Volume: 147, Issue:3

    Topics: Animals; Antineoplastic Agents; Catheter Ablation; Cell Line, Tumor; Chemotherapy, Adjuvant; Colorec

2010
Noninvasive monitoring of radiation-induced early therapeutic response using high-resolution MR imaging and proton MR spectroscopy in VX2 carcinoma.
    Journal of radiation research, 2010, Volume: 51, Issue:6

    Topics: Animals; Choline; Creatine; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2010
Evaluation of initial plasma lactate values as a predictor of gastric necrosis and initial and subsequent plasma lactate values as a predictor of survival in dogs with gastric dilatation-volvulus: 84 dogs (2003-2007).
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2011, Volume: 21, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Female; Gastric Dilatation; Lactic Acid; Male; Necrosis; Retrospective

2011
Lactate MRSI and DCE MRI as surrogate markers of prostate tumor aggressiveness.
    NMR in biomedicine, 2012, Volume: 25, Issue:1

    Topics: Animals; Biomarkers, Tumor; Cell Hypoxia; Contrast Media; Immunohistochemistry; Lactic Acid; Magneti

2012
The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells.
    The Journal of toxicological sciences, 2011, Volume: 36, Issue:3

    Topics: Acetaldehyde; Allergens; Amino Acid Chloromethyl Ketones; Apoptosis; B7-2 Antigen; Caspase Inhibitor

2011
Metabolic targeting of lactate efflux by malignant glioma inhibits invasiveness and induces necrosis: an in vivo study.
    Neoplasia (New York, N.Y.), 2011, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents; Biological Transport; Brain Neoplasms; Cell Line, Tumor; Coumaric Ac

2011
NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration.
    Nature cell biology, 2011, Aug-28, Volume: 13, Issue:10

    Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; bcl-2 Homologous Antagonist-Killer Prote

2011
Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes.
    Apoptosis : an international journal on programmed cell death, 2012, Volume: 17, Issue:6

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Autophagy; Cell Survival; Cells, Cultured; Energy Metabo

2012
Chitosan/PLA nanoparticles as a novel carrier for the delivery of anthraquinone: synthesis, characterization and in vitro cytotoxicity evaluation.
    Colloids and surfaces. B, Biointerfaces, 2013, Jan-01, Volume: 101

    Topics: Annexin A5; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Pro

2013
An oxygen-permeable spheroid culture system for the prevention of central hypoxia and necrosis of spheroids.
    Biomaterials, 2012, Volume: 33, Issue:33

    Topics: Cell Culture Techniques; Cell Hypoxia; Cell Proliferation; Glucose; Hep G2 Cells; Hepatocytes; Human

2012
Evaluation of the effects of thalidomide-loaded biodegradable devices in solid Ehrlich tumor.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:2

    Topics: Absorbable Implants; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Antineoplastic

2013
Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004-2009).
    Journal of the American Veterinary Medical Association, 2013, Jan-01, Volume: 242, Issue:1

    Topics: Acid-Base Imbalance; Animals; Dog Diseases; Dogs; Female; Gastric Dilatation; Lactic Acid; Male; Nec

2013
Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals.
    The Journal of physiology, 2002, Sep-01, Volume: 543, Issue:Pt 2

    Topics: Acid Sensing Ion Channels; Acidosis; Animals; Arachidonic Acid; Brain Ischemia; Cations; gamma-Amino

2002
Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis.
    Neurosurgery, 2002, Volume: 51, Issue:4

    Topics: Adult; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glioma; Humans; Lactic Acid; Lip

2002
The influence of a single acetic acid and lactic acid injection on rat normal thyroid tissue.
    Ceskoslovenska patologie, 2002, Volume: 38, Issue:3

    Topics: Acetic Acid; Animals; Injections; Lactic Acid; Male; Necrosis; Rats; Rats, Wistar; Recurrent Larynge

2002
Investigation of a bioresorbable orbital implant.
    Ophthalmic plastic and reconstructive surgery, 2002, Volume: 18, Issue:5

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Eye Enucleation; Fibrosis; Granuloma, Giant C

2002
Protective effect of ischemic preconditioning against intermittent warm-ischemia-induced liver injury.
    The Journal of surgical research, 2002, Volume: 107, Issue:1

    Topics: Animals; Apoptosis; Aspartate Aminotransferases; Energy Metabolism; Hepatocytes; Hot Temperature; Is

2002
Dobutamine responsiveness, PET mismatch, and lack of necrosis in low-flow ischemia: is this hibernation in the isolated rat heart?
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Creatine Kinase; Dobutamine; Fluorodeoxyglucose F

2003
The effects of dichloroacetate in a rabbit model of acute hind-limb ischemia and reperfusion.
    Journal of the American College of Surgeons, 2003, Volume: 197, Issue:4

    Topics: Animals; Dichloroacetic Acid; Disease Models, Animal; Female; Hindlimb; Ischemia; Lactic Acid; Muscl

2003
Correlation between the occurrence of 1H-MRS lipid signal, necrosis and lipid droplets during C6 rat glioma development.
    NMR in biomedicine, 2003, Volume: 16, Issue:4

    Topics: Animals; Cell Line, Tumor; Female; Glioma; Humans; Inclusion Bodies; Lactic Acid; Lipid Metabolism;

2003
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects.
    Chemical research in toxicology, 2003, Volume: 16, Issue:10

    Topics: Animals; Dose-Response Relationship, Drug; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Mal

2003
Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)- and PKB/AKT-independent fashion.
    Cell death and differentiation, 2004, Volume: 11, Issue:3

    Topics: Adenosine Triphosphate; Apoptosis; bcl-X Protein; Blotting, Western; Caspases; Cell Fractionation; C

2004
Metabolite and diffusion changes in the rat brain after Leksell Gamma Knife irradiation.
    Magnetic resonance in medicine, 2004, Volume: 52, Issue:2

    Topics: Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Hippocampus; Lactic Acid; Magnetic

2004
In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death.
    Hippocampus, 2004, Volume: 14, Issue:5

    Topics: Animals; Apoptosis; Brain; Brain Injuries; Cell Death; Cell Survival; Denervation; Disease Models, A

2004
Citrate shows specific, dose-dependent lympholytic activity in neoplastic cell lines.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:8

    Topics: Acetic Acid; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Citrates; Dose-Response Relationship,

2004
A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother.
    European journal of pediatrics, 2005, Volume: 164, Issue:3

    Topics: Adipose Tissue; Antiretroviral Therapy, Highly Active; Arginine; Asphyxia; Brain; Cardiomegaly; Card

2005
Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death.
    Journal of neuroscience research, 2005, May-15, Volume: 80, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; C

2005
Early postoperative function of the heart after coronary artery bypass grafting is not predicted by myocardial necrosis and glutathione-associated oxidative stress.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 359, Issue:1-2

    Topics: Aged; Coronary Artery Bypass; Female; Glutathione; Heart; Heart Arrest, Induced; Humans; Lactic Acid

2005
The impact of gastrocnemius muscle cell changes in chronic venous insufficiency.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2005, Volume: 30, Issue:4

    Topics: Adult; Aged; Atrophy; Calcium-Transporting ATPases; Case-Control Studies; Electron Transport Complex

2005
Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration.
    Neurochemistry international, 2006, Volume: 49, Issue:4

    Topics: Animals; Apoptosis; Benzimidazoles; Cell Death; Cell Survival; Cells, Cultured; Culture Media; Dopam

2006
Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture.
    Journal of neurochemistry, 2006, Volume: 98, Issue:4

    Topics: Adenosine Triphosphate; Animals; Carbolines; Caspase 3; Caspases; Cell Death; Cell Nucleus; Cells, C

2006
Plasma lactate as a predictor of colonic viability and survival after 360 degrees volvulus of the ascending colon in horses.
    Veterinary surgery : VS, 2007, Volume: 36, Issue:6

    Topics: Animals; Biomarkers; Colonic Diseases; Female; Horse Diseases; Horses; Intestinal Volvulus; Lactic A

2007
Rescue of SCID murine ischemic hindlimbs with pH-modified rhbFGF/poly(DL-lactic-co-glycolic acid) implants.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Oct-08, Volume: 122, Issue:3

    Topics: Angiogenesis Inducing Agents; Animals; Disease Models, Animal; Drug Carriers; Fibroblast Growth Fact

2007
Surgical algorithm for management of HIV lipodystrophy.
    Plastic and reconstructive surgery, 2007, Volume: 120, Issue:7

    Topics: Adipose Tissue; Adult; Algorithms; Back; Cellulose; Disease Progression; Face; Gynecomastia; HIV-Ass

2007
Poststreptococcal dystonia with bilateral striatal enlargement: MR imaging and spectroscopic findings.
    AJNR. American journal of neuroradiology, 2008, Volume: 29, Issue:7

    Topics: Aspartic Acid; Autoantibodies; Bacterial Proteins; Caudate Nucleus; Child; Deoxyribonucleases; Diffu

2008
Systemic and neuropathologic effects of E. coli endotoxin in neonatal dogs.
    Pediatric research, 1983, Volume: 17, Issue:5

    Topics: Acidosis; Animals; Animals, Newborn; Brain; Dogs; Dose-Response Relationship, Drug; Endotoxins; Esch

1983
Metabolic studies of HgCl2-induced acute renal failure in the rat.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:1

    Topics: Acute Kidney Injury; Adenine Nucleotides; Animals; Creatinine; Disease Models, Animal; Dithiothreito

1981
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
    Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:2

    Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fi

1982
Skeletal muscle necrosis and regeneration after injection of BaH1, a hemorrhagic metalloproteinase isolated from the venom of the snake Bothrops asper (Terciopelo).
    Experimental and molecular pathology, 1995, Volume: 62, Issue:1

    Topics: Animals; Bothrops; Crotalid Venoms; Endopeptidases; Hemoglobins; Lactates; Lactic Acid; Mice; Muscle

1995
Correlation of high lactate levels in human cervical cancer with incidence of metastasis.
    Cancer research, 1995, Nov-01, Volume: 55, Issue:21

    Topics: Adenosine Triphosphate; Biopsy; Female; Glucose; Humans; Lactates; Lactic Acid; Luminescent Measurem

1995
Chloropropionic acid-induced alterations in glucose metabolic status: possible relevance to cerebellar granule cell necrosis.
    Archives of toxicology, 1995, Volume: 69, Issue:9

    Topics: Animals; Blood Glucose; Cerebellum; Cytoplasmic Granules; Glucose; Hydrocarbons, Chlorinated; Lactat

1995
Intracoronary application of C1 esterase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusion.
    Circulation, 1997, Feb-04, Volume: 95, Issue:3

    Topics: Anaphylatoxins; Animals; Complement C1 Inactivator Proteins; Coronary Vessels; Creatine Kinase; Fema

1997
Carbohydrates and purines in underperfused hearts, protected by ischemic preconditioning.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Glucose; Glycogen; In Vitro Techniques; Is

1998
[Perforant elastosis serpiginosa associated with Down's syndrome. Report of 2 cases].
    Anales espanoles de pediatria, 1998, Volume: 48, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Biopsy; Child; Down Syndrome; Elastic Tissue; Female; Humans;

1998
Effect of alternative peritoneal dialysis solutions on cell viability, apoptosis/necrosis and cytokine expression in human monocytes.
    Kidney international, 1998, Volume: 54, Issue:1

    Topics: Actins; Apoptosis; Bicarbonates; Buffers; Cell Survival; Dialysis Solutions; Flow Cytometry; Gene Ex

1998
Relation of impaired energy metabolism to apoptosis and necrosis following transient cerebral hypoxia-ischaemia.
    Cell death and differentiation, 1998, Volume: 5, Issue:4

    Topics: Animals; Animals, Newborn; Apoptosis; Brain; Brain Ischemia; Cell Count; Energy Metabolism; Gyrus Ci

1998
Plasma lactate concentration as a predictor of gastric necrosis and survival among dogs with gastric dilatation-volvulus: 102 cases (1995-1998).
    Journal of the American Veterinary Medical Association, 1999, Jul-01, Volume: 215, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Female; Gastric Dilatation; Lactic Acid; Male; Necrosis; Predictive Val

1999
Myocardial cell injury in septic shock.
    Critical care medicine, 1999, Volume: 27, Issue:9

    Topics: Adult; Aged; APACHE; Cardiomyopathies; Case-Control Studies; Catecholamines; Creatine Kinase; Dose-R

1999
Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy.
    Journal of neurosurgery, 1999, Volume: 91, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Nuclear; Biomarkers, Tumor; Brain; Cell Division; Cell Tra

1999
Nitric oxide produced via neuronal NOS may impair vasodilatation in septic rat skeletal muscle.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5

    Topics: Acetylcholine; Animals; Arterioles; Enzyme Inhibitors; Lactic Acid; Male; Muscle, Skeletal; Necrosis

2000
Differences in water diffusion and lactate production in two different types of postinfectious encephalopathy.
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 11, Issue:5

    Topics: Body Water; Brain Chemistry; Brain Diseases; Child; Echo-Planar Imaging; Encephalomyelitis, Acute Di

2000
Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Azides; Caspase Inhibitors; Caspases; Cell Respiration;

2000
Proton magnetic resonance chemical shift imaging (1H CSI)-directed stereotactic biopsy.
    Acta neurochirurgica, 2001, Volume: 143, Issue:1

    Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Ene

2001
Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice.
    International journal of experimental pathology, 2001, Volume: 82, Issue:1

    Topics: Animals; Brazil; Cell Line; Creatine Kinase; Fibrosis; Fish Venoms; Injections, Intramuscular; Lacti

2001
Interstitial lactate in the peritraumatic penumbra of rat brain.
    Acta neurochirurgica. Supplement, 2000, Volume: 76

    Topics: Animals; Brain Damage, Chronic; Brain Edema; Brain Injuries; Cerebral Cortex; Lactic Acid; Male; Nec

2000
Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Sep-01, Volume: 21, Issue:17

    Topics: Adenosine Triphosphate; Animals; Cell Death; Cell Respiration; Cell Survival; Cells, Cultured; Cereb

2001
Peritoneal dialysis fluids with a physiologic pH based on either lactate or bicarbonate buffer-effects on human mesothelial cells.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:4

    Topics: Adenosine Triphosphate; Apoptosis; Bicarbonates; Buffers; Dialysis Solutions; Epithelial Cells; Flow

2001
Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects.
    Circulation, 2001, Dec-18, Volume: 104, Issue:25

    Topics: Anaphylatoxins; Animals; Blood Gas Analysis; Cardiac Output; Complement C1 Inactivator Proteins; Cor

2001
Lactate accumulation rather than ATP depletion predicts ischemic myocardial necrosis: implications for the development of lethal myocardial injury.
    Biochimica et biophysica acta, 2002, Mar-16, Volume: 1586, Issue:2

    Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Lactic Acid; Myocardial Ischemia; Myocardiu

2002
Parenteral aluminum compounds produce a local toxic myopathy in rats: importance of the anion.
    Toxicologic pathology, 1992, Volume: 20, Issue:3 Pt 1

    Topics: Aluminum; Animals; Anions; Antacids; Citrates; Citric Acid; Diaphragm; Female; Infusions, Parenteral

1992
Prolonged adenine nucleotide resynthesis and reperfusion injury in postischemic skeletal muscle.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 2

    Topics: Adenine Nucleotides; Animals; Creatine Kinase; Dogs; Ischemia; Lactates; Lactic Acid; Muscles; Necro

1992
Variations and comparisons in medium-depth chemical peeling.
    The Journal of dermatologic surgery and oncology, 1989, Volume: 15, Issue:9

    Topics: Administration, Topical; Adult; Carbon Dioxide; Chemexfoliation; Drug Combinations; Epidermis; Ethan

1989
[Relation between myocardial perfusion, myocardial necrosis and residual glucose metabolism as a vitality parameter in the post-ischemic myocardium following coronary reperfusion].
    Acta medica Austriaca. Supplement, 1989, Volume: 39

    Topics: Aged; Animals; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Coronary Disease; Coronary

1989
Internal countershock produces myocardial damage and lactate production without myocardial ischemia in anesthetized dogs.
    Anesthesiology, 1987, Volume: 66, Issue:4

    Topics: Animals; Coronary Circulation; Diphosphates; Dogs; Electric Countershock; Hemodynamics; Lactates; La

1987
[Hyperlactacidemia in intestinal ischemia. II. Experimental principles].
    Langenbecks Archiv fur Chirurgie, 1987, Volume: 370, Issue:2

    Topics: Animals; Intestines; Ischemia; Lactates; Lactic Acid; Mesenteric Vascular Occlusion; Necrosis; Pyruv

1987
[Contractile function, glucose consumption and lactate release by the isolated rat heart during different regimens of alcohol administration and after discontinuation of ethanol].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:5

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Glucose; Glycogen; Lactates; Lactic Acid; Myoc

1986
Metabolic alterations underlying the development of hypermetabolic necrosis in the substantia nigra in status epilepticus.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:1

    Topics: Adenosine Triphosphate; Animals; Glucose; Glycogen; Lactates; Lactic Acid; Necrosis; Periaqueductal

1987
Prevention of reperfusional damage from ischemic myocardium.
    The Journal of thoracic and cardiovascular surgery, 1986, Volume: 91, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Cardiopulmonary Bypass; Coronary Circulation; Glucose; H

1986