lactic acid has been researched along with Muscular Dystrophy, Duchenne in 6 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted an open-label study to examine the effects of the flavonoid (-)-epicatechin in seven ambulatory adult patients with Becker muscular dystrophy (BMD)." | 8.02 | (-)-Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy. ( Abresch, RT; Aguilar, C; Ceballos, G; Dayan, J; Dugar, S; Goude, E; Henricson, EK; Joyce, N; McDonald, CM; Nicorici, A; Oskarsson, B; Perkins, G; Ramirez-Sanchez, I; Schreiner, G; Villarreal, F, 2021) |
| "Levosimendan was effective in improving heart function." | 5.51 | Levosimendan as Rescue Therapy for Acute Heart Failure in a Patient with Duchenne Muscular Dystrophy. ( Bergounioux, J; Essid, A; Haegy, I; Josseran, L; Mbieleu, B; Sumanaru, D, 2019) |
| "We conducted an open-label study to examine the effects of the flavonoid (-)-epicatechin in seven ambulatory adult patients with Becker muscular dystrophy (BMD)." | 4.02 | (-)-Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy. ( Abresch, RT; Aguilar, C; Ceballos, G; Dayan, J; Dugar, S; Goude, E; Henricson, EK; Joyce, N; McDonald, CM; Nicorici, A; Oskarsson, B; Perkins, G; Ramirez-Sanchez, I; Schreiner, G; Villarreal, F, 2021) |
| "Levosimendan was effective in improving heart function." | 1.51 | Levosimendan as Rescue Therapy for Acute Heart Failure in a Patient with Duchenne Muscular Dystrophy. ( Bergounioux, J; Essid, A; Haegy, I; Josseran, L; Mbieleu, B; Sumanaru, D, 2019) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| McDonald, CM | 1 |
| Ramirez-Sanchez, I | 1 |
| Oskarsson, B | 1 |
| Joyce, N | 1 |
| Aguilar, C | 1 |
| Nicorici, A | 1 |
| Dayan, J | 1 |
| Goude, E | 1 |
| Abresch, RT | 1 |
| Villarreal, F | 1 |
| Ceballos, G | 1 |
| Perkins, G | 1 |
| Dugar, S | 1 |
| Schreiner, G | 1 |
| Henricson, EK | 1 |
| Sumanaru, D | 1 |
| Josseran, L | 1 |
| Essid, A | 1 |
| Mbieleu, B | 1 |
| Haegy, I | 1 |
| Bergounioux, J | 1 |
| Yokota, T | 1 |
| Miyagoe-Suzuki, Y | 1 |
| Ikemoto, T | 1 |
| Matsuda, R | 1 |
| Takeda, S | 1 |
| Yang, HS | 1 |
| Ieronimakis, N | 1 |
| Tsui, JH | 1 |
| Kim, HN | 1 |
| Suh, KY | 1 |
| Reyes, M | 1 |
| Kim, DH | 1 |
| Sveen, ML | 1 |
| Jeppesen, TD | 1 |
| Hauerslev, S | 1 |
| Køber, L | 1 |
| Krag, TO | 1 |
| Vissing, J | 2 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Effectiveness of Resistance Exercise Training in Patients With Late Onset Pompe Disease- A Pilot Study[NCT02654886] | 10 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| A Clinical Trial, Investigating the Effect of a Home-based Moderate Intensity Training Program on Oxidative Capacity and Hemodynamics in Patients With Truncating Genetic Variants in TTN.[NCT05180188] | 14 participants (Actual) | Interventional | 2022-02-14 | Completed | |||
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lactic acid and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Endurance training improves fitness and strength in patients with Becker muscular dystrophy.
Topics: Activities of Daily Living; Adult; Bicycling; Biopsy; Creatine Kinase; Exercise Therapy; Humans; Lac | 2008 |
Endurance training improves fitness and strength in patients with Becker muscular dystrophy.
Topics: Activities of Daily Living; Adult; Bicycling; Biopsy; Creatine Kinase; Exercise Therapy; Humans; Lac | 2008 |
Endurance training improves fitness and strength in patients with Becker muscular dystrophy.
Topics: Activities of Daily Living; Adult; Bicycling; Biopsy; Creatine Kinase; Exercise Therapy; Humans; Lac | 2008 |
Endurance training improves fitness and strength in patients with Becker muscular dystrophy.
Topics: Activities of Daily Living; Adult; Bicycling; Biopsy; Creatine Kinase; Exercise Therapy; Humans; Lac | 2008 |
5 other studies available for lactic acid and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
(-)-Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy.
Topics: Adult; Biopsy; Blotting, Western; Catechin; Creatine Kinase; Dysferlin; Exercise Test; Follistatin; | 2021 |
Levosimendan as Rescue Therapy for Acute Heart Failure in a Patient with Duchenne Muscular Dystrophy.
Topics: Acute Disease; Adult; Cardiomyopathies; Cardiotonic Agents; Heart Failure; Humans; Lactic Acid; Male | 2019 |
α1-Syntrophin-deficient mice exhibit impaired muscle force recovery after osmotic shock.
Topics: Animals; Calcium-Binding Proteins; Disease Models, Animal; In Vitro Techniques; Lactic Acid; Membran | 2014 |
Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy.
Topics: Animals; Disease Models, Animal; Dystrophin; Lactic Acid; Male; Mice; Microscopy, Atomic Force; Musc | 2014 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |