lactic acid has been researched along with Muscular Atrophy in 17 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We observed that 1) the locomotor recovery pattern, analyzed with kinetic parameters and peroneal functional index, was superior in the GS and CT groups; 2) a muscle contraction was obtained in all groups after stimulation of the proximal nerve but the mechanical muscle properties (twitch and tetanus threshold) parameters indicated a fast to slow fiber transition in all operated groups; 3) the muscular atrophy was greater in animals from TM group; 4) the metabosensitive afferent responses to electrically induced fatigue and to two chemical agents (KCl and lactic acid) was altered in GS, CT and TM groups; 5) the empty collagen tube supported motor axonal regeneration." | 3.75 | Functional recovery after peripheral nerve injury and implantation of a collagen guide. ( Alluin, O; Chabas, JF; Decherchi, P; Feron, F; Garcia, S; Guinard, D; Lavaut, MN; Marqueste, T; Wittmann, C, 2009) |
| "Extensive muscle atrophy is a common occurrence in orthopaedics patients who are bedridden or immobilized." | 3.11 | Prevention of muscle atrophy in ICU patients without nerve injury by neuromuscular electrical stimulation: a randomized controlled study. ( Bai, Y; Bao, W; Chen, K; Li, M; Ma, Z; Xu, Y; Yang, J, 2022) |
| "The primary deleterious changes are muscle atrophy and the associated decline in peak force and power." | 2.41 | Functional and structural adaptations of skeletal muscle to microgravity. ( Fitts, RH; Riley, DR; Widrick, JJ, 2001) |
| "Sepsis is a systemic inflammatory response syndrome resulting from infection." | 1.51 | MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway. ( Bai, YP; Li, J; Li, TM; Liu, L; Liu, XR; Tang, N; Wang, XB, 2019) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| "Muscle histometry in patients with chronic fatigue syndrome generally did not show the changes expected as a result of inactivity." | 1.30 | Muscle fibre characteristics and lactate responses to exercise in chronic fatigue syndrome. ( Archard, LC; Barrett, MC; Fletcher, R; Lane, RJ; Moss, J; Woodrow, D, 1998) |
| "Three patients with chronic progressive external ophthalmoplegia of adult-onset, generalized muscle atrophy and myalgia are described." | 1.29 | Mitochondrial dysfunction in adult-onset myopathies with structural abnormalities. ( Gold, R; Klopstock, T; Naumann, M; Paulus, W; Reichmann, H; Reiners, K; Schindler, R, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, S | 1 |
| Choi, CH | 1 |
| Lee, BJ | 1 |
| Park, JH | 1 |
| Son, KH | 1 |
| Byun, K | 1 |
| Bao, W | 1 |
| Yang, J | 1 |
| Li, M | 1 |
| Chen, K | 1 |
| Ma, Z | 1 |
| Bai, Y | 1 |
| Xu, Y | 1 |
| Liu, L | 1 |
| Li, TM | 1 |
| Liu, XR | 1 |
| Bai, YP | 1 |
| Li, J | 1 |
| Tang, N | 1 |
| Wang, XB | 1 |
| Padrão, AI | 1 |
| Oliveira, P | 1 |
| Vitorino, R | 1 |
| Colaço, B | 1 |
| Pires, MJ | 1 |
| Márquez, M | 1 |
| Castellanos, E | 1 |
| Neuparth, MJ | 1 |
| Teixeira, C | 1 |
| Costa, C | 1 |
| Moreira-Gonçalves, D | 1 |
| Cabral, S | 1 |
| Duarte, JA | 1 |
| Santos, LL | 1 |
| Amado, F | 1 |
| Ferreira, R | 1 |
| Weber, T | 1 |
| Ducos, M | 1 |
| Mulder, E | 1 |
| Beijer, Å | 1 |
| Herrera, F | 1 |
| Zange, J | 1 |
| Degens, H | 1 |
| Bloch, W | 1 |
| Rittweger, J | 1 |
| Mueller, SM | 1 |
| Aguayo, D | 1 |
| Zuercher, M | 1 |
| Fleischmann, O | 1 |
| Boutellier, U | 1 |
| Auer, M | 1 |
| Jung, HH | 1 |
| Toigo, M | 1 |
| Alluin, O | 1 |
| Wittmann, C | 1 |
| Marqueste, T | 1 |
| Chabas, JF | 1 |
| Garcia, S | 1 |
| Lavaut, MN | 1 |
| Guinard, D | 1 |
| Feron, F | 1 |
| Decherchi, P | 1 |
| Wood, MD | 1 |
| Gordon, T | 1 |
| Kemp, SW | 1 |
| Liu, EH | 1 |
| Kim, H | 1 |
| Shoichet, MS | 1 |
| Borschel, GH | 1 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Vissing, J | 1 |
| Cade, P | 1 |
| Venkatarami Reddy, K | 1 |
| Dhananjaya Reddy, Y | 1 |
| Govindappa, S | 1 |
| Reddanna, P | 1 |
| Naumann, M | 1 |
| Reiners, K | 1 |
| Gold, R | 1 |
| Schindler, R | 1 |
| Paulus, W | 1 |
| Klopstock, T | 1 |
| Reichmann, H | 1 |
| Wassif, WS | 1 |
| Sherman, D | 1 |
| Salisbury, JR | 1 |
| Peters, TJ | 1 |
| Lane, RJ | 1 |
| Barrett, MC | 1 |
| Woodrow, D | 1 |
| Moss, J | 1 |
| Fletcher, R | 1 |
| Archard, LC | 1 |
| Belardinelli, R | 1 |
| Fitts, RH | 1 |
| Riley, DR | 1 |
| Widrick, JJ | 1 |
| Beyenburg, S | 1 |
| von Wersebe, O | 1 |
| Zierz, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of a 56day Unilateral Muscular Unloading Intervention With a Novel Device That Allows Normal Ambulation While Reducing Muscle Activation Drastically, on Muscles, Bones and Vessels.[NCT01576081] | 11 participants (Actual) | Interventional | 2011-04-30 | Completed | |||
| Effects of High-intensity Interval Training in Combination With Side-alternating Whole-body Vibration[NCT01875146] | 33 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| Effects of a Cocktail XXS-2A/Omega-3 on Insulin Sensitivity and Oxidative Stress During a 20-day Period of Physical Inactivity: a Controlled, Randomized Pilot Study on 20 Healthy Men[NCT03313869] | 20 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| A New Paradigm of Neuromuscular Electrical Stimulation in Attenuating Muscle Atrophy: a Randomised Controlled Trial[NCT02321163] | 105 participants (Anticipated) | Interventional | 2016-02-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Muscular Atrophy
| Article | Year |
|---|---|
[Physiopathology of exercise. Muscular adaptations].
Topics: Adaptation, Physiological; Anaerobic Threshold; Biopsy; Exercise; Exercise Test; Exercise Tolerance; | 2000 |
Functional and structural adaptations of skeletal muscle to microgravity.
Topics: Animals; Astronauts; Contractile Proteins; Glycogen; Humans; Lactic Acid; Microscopy, Electron; Musc | 2001 |
Functional and structural adaptations of skeletal muscle to microgravity.
Topics: Animals; Astronauts; Contractile Proteins; Glycogen; Humans; Lactic Acid; Microscopy, Electron; Musc | 2001 |
Functional and structural adaptations of skeletal muscle to microgravity.
Topics: Animals; Astronauts; Contractile Proteins; Glycogen; Humans; Lactic Acid; Microscopy, Electron; Musc | 2001 |
Functional and structural adaptations of skeletal muscle to microgravity.
Topics: Animals; Astronauts; Contractile Proteins; Glycogen; Humans; Lactic Acid; Microscopy, Electron; Musc | 2001 |
3 trials available for lactic acid and Muscular Atrophy
| Article | Year |
|---|---|
Prevention of muscle atrophy in ICU patients without nerve injury by neuromuscular electrical stimulation: a randomized controlled study.
Topics: C-Reactive Protein; Electric Stimulation Therapy; Humans; Intensive Care Units; Lactic Acid; Muscle | 2022 |
High-intensity interval training with vibration as rest intervals attenuates fiber atrophy and prevents decreases in anaerobic performance.
Topics: Adult; Anaerobiosis; Cardiac Output; Electromyography; Exercise; Heart Rate; Humans; Lactic Acid; Ma | 2015 |
Use of dynamic tests of muscle function and histomorphometry of quadriceps muscle biopsies in the investigation of patients with chronic alcohol misuse and chronic fatigue syndrome.
Topics: Adult; Alcoholism; Ammonia; AMP Deaminase; Analysis of Variance; Biopsy, Needle; Creatine Kinase; Di | 1994 |
12 other studies available for lactic acid and Muscular Atrophy
| Article | Year |
|---|---|
Fermented Oyster Extract Attenuated Dexamethasone-Induced Muscle Atrophy by Decreasing Oxidative Stress.
Topics: Adaptor Proteins, Signal Transducing; Animals; Dexamethasone; Fermentation; Forkhead Box Protein O3; | 2021 |
MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Cells, Cultured; Cytokines; Disease | 2019 |
Bladder cancer-induced skeletal muscle wasting: disclosing the role of mitochondria plasticity.
Topics: 1-Naphthylamine; Animals; Apoptosis Regulatory Proteins; Boronic Acids; C-Reactive Protein; Cytokine | 2013 |
The relationship between exercise-induced muscle fatigue, arterial blood flow and muscle perfusion after 56 days local muscle unloading.
Topics: Adult; Biomechanical Phenomena; Blood Flow Velocity; Femoral Artery; Humans; Lactic Acid; Leg; Male; | 2014 |
Functional recovery after peripheral nerve injury and implantation of a collagen guide.
Topics: Afferent Pathways; Animals; Axons; Collagen; Electricity; Hindlimb; Implants, Experimental; Injectio | 2009 |
Functional motor recovery is improved due to local placement of GDNF microspheres after delayed nerve repair.
Topics: Analysis of Variance; Animals; Axons; Drug Carriers; Female; Fibrin Tissue Adhesive; Glial Cell Line | 2013 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
Leg training. Accessing the body's energy reserves.
Topics: Adenosine Triphosphate; Energy Metabolism; Exercise Therapy; Humans; Kidney Failure, Chronic; Lactic | 2004 |
Induced muscular work overload and disuse on the serum carbohydrate metabolism of dog, Canis domesticus.
Topics: Animals; Blood Glucose; Carbohydrates; Dogs; Electric Stimulation; Lactates; Lactic Acid; Male; Musc | 1983 |
Mitochondrial dysfunction in adult-onset myopathies with structural abnormalities.
Topics: Adult; Age of Onset; Creatine Kinase; Electron Transport Complex IV; Female; Humans; Hydrogen-Ion Co | 1995 |
Muscle fibre characteristics and lactate responses to exercise in chronic fatigue syndrome.
Topics: Adult; Anaerobic Threshold; Biopsy, Needle; Exercise; Exercise Test; Fatigue Syndrome, Chronic; Fema | 1998 |
[Delayed manifestation of mitochondrial myopathy--complex I and IV deficiency of the mitochondrial respiratory chain with progressive paresis].
Topics: Biopsy; Cytochrome-c Oxidase Deficiency; Electromyography; Humans; Lactates; Lactic Acid; Male; Midd | 1991 |