lactic acid has been researched along with Muscular Atrophy, Spinal in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proximal Spinal Muscular Atrophy (SMA) is a debilitating neuromuscular disease and a leading inherited genetic cause of infant death." | 1.38 | Prediction of death in the SMNΔ7 mouse model of spinal muscular atrophy: insight into disease stage and progression. ( Beltran, JA; Charney, R; Chomicova, O; Cirillo, K; El-Khodor, BF; Marino, T; Mushlin, R; Ramboz, S; Winberg, ML, 2012) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Khodor, BF | 1 |
| Cirillo, K | 1 |
| Beltran, JA | 1 |
| Mushlin, R | 1 |
| Winberg, ML | 1 |
| Charney, R | 1 |
| Chomicova, O | 1 |
| Marino, T | 1 |
| Ramboz, S | 1 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Vissing, J | 1 |
| Karitzky, J | 1 |
| Block, W | 1 |
| Mellies, JK | 1 |
| Träber, F | 1 |
| Sperfeld, A | 1 |
| Schild, HH | 1 |
| Haller, P | 1 |
| Ludolph, AC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for lactic acid and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Prediction of death in the SMNΔ7 mouse model of spinal muscular atrophy: insight into disease stage and progression.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Brain; Computer Simulation; Dichloroacetic Acid | 2012 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
Proton magnetic resonance spectroscopy in Kennedy syndrome.
Topics: Acetylation; Adult; Brain Stem; Choline; Family Health; Gliosis; Humans; Lactic Acid; Magnetic Reson | 1999 |