lactic acid has been researched along with Microcephaly in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Microcephaly: A congenital abnormality in which the CEREBRUM is underdeveloped, the fontanels close prematurely, and, as a result, the head is small. (Desk Reference for Neuroscience, 2nd ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amish microcephaly (MCPHA, OMIM #607196) is a metabolic disorder that has been previously characterized by severe infantile lethal congenital microcephaly and alpha-ketoglutaric aciduria." | 1.36 | Amish microcephaly: Long-term survival and biochemical characterization. ( Prasad, AN; Prasad, C; Ratko, S; Rupar, CA; Siu, VM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siu, VM | 1 |
| Ratko, S | 1 |
| Prasad, AN | 1 |
| Prasad, C | 1 |
| Rupar, CA | 1 |
| Cassandrini, D | 1 |
| Cilio, MR | 1 |
| Bianchi, M | 1 |
| Doimo, M | 1 |
| Balestri, M | 1 |
| Tessa, A | 1 |
| Rizza, T | 1 |
| Sartori, G | 1 |
| Meschini, MC | 1 |
| Nesti, C | 1 |
| Tozzi, G | 1 |
| Petruzzella, V | 1 |
| Piemonte, F | 1 |
| Bisceglia, L | 1 |
| Bruno, C | 1 |
| Dionisi-Vici, C | 1 |
| D'Amico, A | 1 |
| Fattori, F | 1 |
| Carrozzo, R | 1 |
| Salviati, L | 1 |
| Santorelli, FM | 1 |
| Bertini, E | 1 |
| Sperl, W | 1 |
| Jesina, P | 1 |
| Zeman, J | 1 |
| Mayr, JA | 1 |
| Demeirleir, L | 1 |
| VanCoster, R | 1 |
| Pícková, A | 1 |
| Hansíková, H | 1 |
| Houst'ková, H | 1 |
| Krejcík, Z | 1 |
| Koch, J | 1 |
| Smet, J | 1 |
| Muss, W | 1 |
| Holme, E | 1 |
| Houstek, J | 1 |
3 other studies available for lactic acid and Microcephaly
| Article | Year |
|---|---|
Amish microcephaly: Long-term survival and biochemical characterization.
Topics: Adult; Child; Ethnicity; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Im | 2010 |
Pontocerebellar hypoplasia type 6 caused by mutations in RARS2: definition of the clinical spectrum and molecular findings in five patients.
Topics: Arginine-tRNA Ligase; Cerebellum; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infan | 2013 |
Deficiency of mitochondrial ATP synthase of nuclear genetic origin.
Topics: Adenosine Triphosphate; Adolescent; Age of Onset; Cardiomyopathy, Hypertrophic, Familial; Cell Nucle | 2006 |