lactic acid has been researched along with Metabolic Diseases in 19 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Suspected antiretroviral toxicities meeting these criteria include: HIV-associated lipodystrophy which can include peripheral lipoatrophy, lipohypertrophy and metabolic abnormalities; hyperlactatemia and lactic acidosis; and metabolic bone abnormalities such as decreased bone mineral density, osteoporosis and osteonecrosis." | 4.82 | Emerging drug toxicities of highly active antiretroviral therapy for human immunodeficiency virus (HIV) infection. ( Bondy, G; Heath, KV; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Singer, J, 2003) |
| "An LP ratio >25 and glycerol >100 micromol/L, but not glutamate >12 micromol/L, were associated with significantly higher risk of imminent intracranial hypertension (odds ratio: 9." | 3.74 | Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study. ( Belli, A; Kitchen, N; Petzold, A; Russo, S; Sen, J; Smith, M, 2008) |
| " Hypoxia induced an immediate and significant elevation in the intraperitoneal lactate/pyruvate ratio to 446+/-137% of the baseline values, and glycerol subsequently increased during reoxygenation to 389+/-109%." | 3.71 | Intraperitoneal microdialysis for detection of splanchnic metabolic disorders. ( Bahlmann, L; Bruch, HP; Gliemroth, J; Heringlake, M; Klaus, S, 2002) |
| " Lactic acidosis, characterized by metabolic acidosis, blood lactate above 5 mmol/l, hepatic steatosis and high mortality, represents the extreme end of this spectrum where there is complete decompensation." | 3.71 | Hyperlactatemia syndromes in people with HIV infection. ( John, M; Mallal, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Baryła, I | 1 |
| Styczeń-Binkowska, E | 1 |
| Płuciennik, E | 1 |
| Kośla, K | 1 |
| Bednarek, AK | 1 |
| Chen, WJ | 1 |
| Huang, SY | 1 |
| Chen, YW | 2 |
| Liu, YF | 1 |
| Huang, RS | 1 |
| Heimer, J | 1 |
| Gascho, D | 1 |
| Madea, B | 1 |
| Steuer, A | 1 |
| Martinez, RM | 1 |
| Thali, MJ | 1 |
| Zoelch, N | 1 |
| Tsai, SF | 1 |
| Kuo, YM | 1 |
| Zhang, X | 1 |
| Yu, Y | 1 |
| Shen, J | 1 |
| Qi, W | 1 |
| Wang, H | 1 |
| Rassu, G | 1 |
| Salis, A | 1 |
| Porcu, EP | 1 |
| Giunchedi, P | 1 |
| Roldo, M | 1 |
| Gavini, E | 1 |
| Bellomo, R | 1 |
| Märtensson, J | 1 |
| Eastwood, GM | 1 |
| Daniels, IS | 1 |
| Zhang, J | 1 |
| O'Brien, WG | 1 |
| Tao, Z | 1 |
| Miki, T | 1 |
| Zhao, Z | 1 |
| Blackburn, MR | 1 |
| Lee, CC | 1 |
| Santos, E | 1 |
| Orakcioglu, B | 1 |
| Kentar, MM | 1 |
| Diedler, J | 1 |
| Uozumi, Y | 1 |
| Schöll, M | 1 |
| Unterberg, A | 1 |
| Sakowitz, OW | 1 |
| Schambelan, M | 1 |
| Benson, CA | 1 |
| Carr, A | 1 |
| Currier, JS | 1 |
| Dubé, MP | 1 |
| Gerber, JG | 1 |
| Grinspoon, SK | 1 |
| Grunfeld, C | 1 |
| Kotler, DP | 1 |
| Mulligan, K | 1 |
| Powderly, WG | 1 |
| Saag, MS | 1 |
| Klaus, S | 1 |
| Heringlake, M | 1 |
| Gliemroth, J | 1 |
| Bruch, HP | 1 |
| Bahlmann, L | 1 |
| Heath, KV | 1 |
| Montaner, JS | 1 |
| Bondy, G | 1 |
| Singer, J | 1 |
| O'Shaughnessy, MV | 1 |
| Hogg, RS | 1 |
| DAUBRESSE, E | 1 |
| DAUBRESSE, JL | 1 |
| DALLA TORRE, L | 1 |
| Bal, D | 1 |
| Kraska-Dziadecka, A | 1 |
| Gradowska, W | 1 |
| Gryff-Keller, A | 1 |
| Belli, A | 1 |
| Sen, J | 1 |
| Petzold, A | 1 |
| Russo, S | 1 |
| Kitchen, N | 1 |
| Smith, M | 1 |
| Bruno, C | 1 |
| Bado, M | 1 |
| Minetti, C | 1 |
| Cordone, G | 1 |
| John, M | 1 |
| Mallal, S | 1 |
| Nashef, L | 1 |
| Lane, RJ | 1 |
3 reviews available for lactic acid and Metabolic Diseases
| Article | Year |
|---|---|
Metabolic and electrolyte disturbance after cardiac arrest: How to deal with it.
Topics: Blood Glucose; Electrolytes; Heart Arrest; Humans; Hyperglycemia; Lactic Acid; Metabolic Diseases; W | 2015 |
Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel.
Topics: Adipose Tissue; Anti-HIV Agents; Bone Diseases, Metabolic; Glucose; HIV Infections; HIV-1; Homeostas | 2002 |
Emerging drug toxicities of highly active antiretroviral therapy for human immunodeficiency virus (HIV) infection.
Topics: Acidosis, Lactic; Antiretroviral Therapy, Highly Active; Bone Diseases, Metabolic; DNA, Mitochondria | 2003 |
16 other studies available for lactic acid and Metabolic Diseases
| Article | Year |
|---|---|
The
Topics: Animals; Down-Regulation; Glucose; Glycolysis; Humans; Hyperglycemia; Hypoxia; Hypoxia-Inducible Fac | 2022 |
Dietary Folate Deficiency Promotes Lactate Metabolic Disorders to Sensitize Lung Cancer Metastasis through MTOR-Signaling-Mediated Druggable Oncotargets.
Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; L-Lactate Dehydrogenase; Lactic Acid; Lung Neoplas | 2023 |
Comparison of the beta-hydroxybutyrate, glucose, and lactate concentrations derived from postmortem proton magnetic resonance spectroscopy and biochemical analysis for the diagnosis of fatal metabolic disorders.
Topics: 3-Hydroxybutyric Acid; Autopsy; Biomarkers; Glucose; Humans; Lactic Acid; Lateral Ventricles; Metabo | 2020 |
High-fat diet reduces the hippocampal content level of lactate which is correlated with the expression of glial glutamate transporters.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Ami | 2018 |
Fabrication of polyethyleneimine-functionalized reduced graphene oxide-hemin-bovine serum albumin (PEI-rGO-hemin-BSA) nanocomposites as peroxidase mimetics for the detection of multiple metabolites.
Topics: Animals; Cattle; Cholesterol; Choline; Glucose; Graphite; Hemin; Humans; Lactic Acid; Metabolic Dise | 2019 |
Composite chitosan/alginate hydrogel for controlled release of deferoxamine: A system to potentially treat iron dysregulation diseases.
Topics: Alginates; Chemistry, Pharmaceutical; Chitosan; Deferoxamine; Delayed-Action Preparations; Drug Carr | 2016 |
A role of erythrocytes in adenosine monophosphate initiation of hypometabolism in mammals.
Topics: 2,3-Diphosphoglycerate; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Chromatogr | 2010 |
Pressure reactivity index correlates with metabolic dysfunction in a porcine model of intracerebral hemorrhage.
Topics: Animals; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; G | 2012 |
Intraperitoneal microdialysis for detection of splanchnic metabolic disorders.
Topics: Animals; Ascitic Fluid; Cryoprotective Agents; Disease Models, Animal; Extracellular Space; Gastroin | 2002 |
[Toxic intermediary metabolites. Determination of pyruvic, alpha-ketoglutaric and lactic acids by the method fo enzymatic tests].
Topics: Disease; Humans; Kernicterus; Lactates; Lactic Acid; Metabolic Diseases; Pyruvates | 1960 |
[Contribution to the knowledge of pyruvic and lactic acid in cardiovascular insufficiency; effect of cocarboxylase].
Topics: Cardiovascular Diseases; Cardiovascular System; Lactic Acid; Metabolic Diseases; Pyruvates; Thiamine | 1952 |
Investigation of a wide spectrum of inherited metabolic disorders by 13C NMR spectroscopy.
Topics: Biomarkers; Canavan Disease; Glutarates; Hemiterpenes; Humans; Lactic Acid; Magnetic Resonance Spect | 2008 |
Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study.
Topics: Biomarkers; Brain; Brain Injuries; Glutamic Acid; Glycerol; Humans; Intracranial Hypertension; Lacti | 2008 |
Forearm semi-ischemic exercise test in pediatric patients.
Topics: Adolescent; Ammonia; Child; Exercise Test; Forearm; Humans; Lactic Acid; Metabolic Diseases; Reperfu | 1998 |
Hyperlactatemia syndromes in people with HIV infection.
Topics: Acidosis, Lactic; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; HIV Infections; Homeostas | 2002 |
Screening for mitochondrial cytopathies: the sub-anaerobic threshold exercise test (SATET).
Topics: Adult; Aged; Anaerobic Threshold; Female; Humans; Lactates; Lactic Acid; Male; Metabolic Diseases; M | 1989 |