lactic acid has been researched along with Meningitis, Viral in 24 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Meningitis, Viral: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 31 cases of proved viral meningitis as with 58 cases of clinically diagnosed viral meningitis, levels were below 3." | 5.26 | Cerebrospinal fluid lactic acidosis in bacterial meningitis. ( Dorman, D; Eross, J; Silink, M, 1981) |
| "Group 2 included 20 patients with viral meningitis." | 1.91 | Cerebrospinal Fluid Lactate as a Differential Biomarker for Bacterial and Viral Meningitis. ( Arafa, ZAA; ElMasry, SA; Fahim, NA; Gabr, MS; Kamel, EM, 2023) |
| "CSF glucose was significantly lower in bacterial meningitis cases (P<0." | 1.51 | Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis. ( Domingues, RB; Fernandes, GBP; Leite, FBVM; Senne, C, 2019) |
| "Differentiating bacterial meningitis from viral meningitis is a diagnostic challenge." | 1.43 | Cerebrospinal fluid lactate: measurement of an adult reference interval. ( Allgar, V; Holbrook, IB; Slack, SD; Turley, P, 2016) |
| "CSF LA in the groups with viral meningitis was not different compared to groups with non-infectious CNS diseases and chronic meningitis." | 1.35 | Quantitation of cerebrospinal fluid lactic acid in infectious and non-infectious neurological diseases. ( Berto, DB; Buczenko, GM; de Almeida, SM; de Goes Fontes, K; Faria, FL; Nogueira, MB; Raboni, SM; Vidal, LR, 2009) |
| "Among 53 bacterial meningitis patients, Neisseria meningitides were isolated in 29 (54." | 1.35 | CSF lactate level: a useful diagnostic tool to differentiate acute bacterial and viral meningitis. ( Abdou, AS; Abro, AH; Doleh, WF; Saleh, AA; Ustadi, AM; Younis, NJ, 2009) |
| "In search for a supplementary marker of bacterial meningitis in cases where conventional bacteriology, cytology and chemistry are insufficiently contributive to diagnosis, we assessed the value of cerebrospinal fluid lactate levels in children with bacterial meningitis." | 1.30 | [Assay of lactic acid in the cerebrospinal fluid for the diagnosis of bacterial meningitis. Strategies for the choice of discriminatory threshold]. ( Bosson, JL; François, P; Kayemba Kay'S, S; Lafond, JL; Pavese, P, 1997) |
| "In multiple sclerosis, myelopathy, stroke, epilepsy and viral meningitis glutamate, hypoxanthine, xanthine, and uric acid are increased 2-3-fold compared to controls." | 1.30 | Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. ( Kempski, OS; Lowitzsch, K; Stover, JF, 1997) |
| "However, distinction between untreated pyogenic meningitis and virus meningitis is rarely problematic in clinical practice, so routine use of the test as an emergency procedure offers no extra advantage." | 1.27 | How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis? ( Dunbar, EM; Hooper, J; Mandal, BK; Parker, L, 1983) |
| "In 31 cases of proved viral meningitis as with 58 cases of clinically diagnosed viral meningitis, levels were below 3." | 1.26 | Cerebrospinal fluid lactic acidosis in bacterial meningitis. ( Dorman, D; Eross, J; Silink, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (25.00) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 4 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arafa, ZAA | 1 |
| Gabr, MS | 1 |
| Kamel, EM | 1 |
| ElMasry, SA | 1 |
| Fahim, NA | 1 |
| de Almeida, SM | 4 |
| Furlan, SMP | 1 |
| Cretella, AMM | 1 |
| Lapinski, B | 1 |
| Nogueira, K | 2 |
| Cogo, LL | 2 |
| Vidal, LRR | 1 |
| Nogueira, MB | 4 |
| Baheerathan, A | 1 |
| Pitceathly, RD | 1 |
| Curtis, C | 1 |
| Davies, NW | 1 |
| Barros, N | 1 |
| Fernandes Dos Santos, A | 1 |
| Custodio, G | 1 |
| Petterle, RR | 1 |
| Sanaei Dashti, A | 1 |
| Alizadeh, S | 1 |
| Karimi, A | 1 |
| Khalifeh, M | 1 |
| Shoja, SA | 1 |
| Domingues, RB | 1 |
| Fernandes, GBP | 1 |
| Leite, FBVM | 1 |
| Senne, C | 1 |
| Slack, SD | 1 |
| Turley, P | 1 |
| Allgar, V | 1 |
| Holbrook, IB | 1 |
| Giulieri, S | 1 |
| Chapuis-Taillard, C | 1 |
| Jaton, K | 1 |
| Cometta, A | 1 |
| Chuard, C | 1 |
| Hugli, O | 1 |
| Du Pasquier, R | 1 |
| Bille, J | 1 |
| Meylan, P | 1 |
| Manuel, O | 1 |
| Marchetti, O | 1 |
| Faria, FL | 1 |
| de Goes Fontes, K | 1 |
| Buczenko, GM | 1 |
| Berto, DB | 1 |
| Raboni, SM | 2 |
| Vidal, LR | 2 |
| Abro, AH | 1 |
| Abdou, AS | 1 |
| Ustadi, AM | 1 |
| Saleh, AA | 1 |
| Younis, NJ | 1 |
| Doleh, WF | 1 |
| Boritza, K | 1 |
| Pessa, L | 1 |
| França, J | 1 |
| Rota, I | 1 |
| Muro, M | 1 |
| Ribeiro, C | 1 |
| Ellis, R | 1 |
| Viallon, A | 1 |
| Desseigne, N | 1 |
| Marjollet, O | 1 |
| Birynczyk, A | 1 |
| Belin, M | 1 |
| Guyomarch, S | 1 |
| Borg, J | 1 |
| Pozetto, B | 1 |
| Bertrand, JC | 1 |
| Zeni, F | 1 |
| Zhang, H | 2 |
| Wang, X | 1 |
| Yang, Y | 1 |
| Wu, J | 1 |
| Chen, Z | 1 |
| Wang, Y | 1 |
| Zeng, A | 1 |
| Chen, L | 1 |
| Wu, R | 1 |
| Chen, B | 1 |
| Chen, M | 1 |
| Bo, J | 1 |
| Peng, Q | 1 |
| Lu, J | 1 |
| Meng, QH | 1 |
| Cunha, BA | 1 |
| Beloborodov, VB | 1 |
| Heil, W | 1 |
| Rick, W | 1 |
| Ruf, B | 1 |
| Mandal, BK | 1 |
| Dunbar, EM | 1 |
| Hooper, J | 1 |
| Parker, L | 1 |
| Eross, J | 1 |
| Silink, M | 1 |
| Dorman, D | 1 |
| Pavese, P | 1 |
| François, P | 1 |
| Lafond, JL | 1 |
| Kayemba Kay'S, S | 1 |
| Bosson, JL | 1 |
| Stover, JF | 1 |
| Lowitzsch, K | 1 |
| Kempski, OS | 1 |
| Lindquist, L | 1 |
| Linné, T | 1 |
| Hansson, LO | 1 |
| Kalin, M | 1 |
| Axelsson, G | 1 |
| Hornig, CR | 1 |
| Dorndorf, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Diagnosis and Treatment Monitoring of Native and Device-associated Meningitis Using D-lactate, a Pathogen-specific Diagnostic Biomarker in Cerebrospinal Fluid[NCT05146570] | 842 participants (Anticipated) | Interventional | 2021-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Meningitis, Viral
| Article | Year |
|---|---|
CSF lactate.
Topics: Adult; Biomarkers; Brain Diseases; Central Nervous System Infections; Enterovirus; Female; Humans; L | 2020 |
[Up-to-date antibacterial therapy of purulent meningitis].
Topics: Anti-Bacterial Agents; C-Reactive Protein; Calcitonin; Diagnosis, Differential; Drugs, Generic; Huma | 2006 |
22 other studies available for lactic acid and Meningitis, Viral
| Article | Year |
|---|---|
Cerebrospinal Fluid Lactate as a Differential Biomarker for Bacterial and Viral Meningitis.
Topics: Biomarkers; Diagnosis, Differential; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Viral; | 2023 |
Comparison of Cerebrospinal Fluid Biomarkers for Differential Diagnosis of Acute Bacterial and Viral Meningitis with Atypical Cerebrospinal Fluid Characteristics.
Topics: Adolescent; Adult; Biomarkers; Blood Glucose; Child; Diagnosis, Differential; Female; Glucose; Human | 2020 |
Clinical performance of amperometry compared with enzymatic ultra violet method for lactate quantification in cerebrospinal fluid.
Topics: Biomarkers; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Viral; Retrospective Studies | 2021 |
Diagnostic value of lactate, procalcitonin, ferritin, serum-C-reactive protein, and other biomarkers in bacterial and viral meningitis: A cross-sectional study.
Topics: Adolescent; Biomarkers; C-Reactive Protein; Calcitonin; Child; Child Health Services; Child, Prescho | 2017 |
Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis.
Topics: Biomarkers; Community-Acquired Infections; Enterovirus Infections; Humans; Lactic Acid; Meningitis, | 2019 |
Cerebrospinal fluid lactate: measurement of an adult reference interval.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Chemistry Tests; Diagnosis, Differential; Femal | 2016 |
CSF lactate for accurate diagnosis of community-acquired bacterial meningitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Cross Infection; Female; Humans; Lactic | 2015 |
Quantitation of cerebrospinal fluid lactic acid in infectious and non-infectious neurological diseases.
Topics: Adult; Biomarkers; Cerebrospinal Fluid; Diagnosis, Differential; Female; Humans; Lactic Acid; Leukoc | 2009 |
CSF lactate level: a useful diagnostic tool to differentiate acute bacterial and viral meningitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Analysis of Variance; Cerebrospinal Fluid; Diagnosis, Differ | 2009 |
Quantification of cerebrospinal fluid lactic acid in the differential diagnosis between HIV chronic meningitis and opportunistic meningitis.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Biomarkers; Child; Child, Preschool; Chron | 2011 |
Meningitis in adult patients with a negative direct cerebrospinal fluid examination: value of cytochemical markers for differential diagnosis.
Topics: Acute Disease; Adolescent; Adult; Aged; Area Under Curve; Biomarkers; C-Reactive Protein; Calcitonin | 2011 |
Meningitis in patients with a Gram-negative direct cerebrospinal fluid examination: the value of cytochemical markers for the differential diagnosis.
Topics: Calcitonin; Female; Humans; Lactic Acid; Male; Meningitis, Bacterial; Meningitis, Viral; Protein Pre | 2011 |
The clinical diagnostic significance of cerebrospinal fluid D-lactate for bacterial meningitis.
Topics: Adolescent; Adult; Aged; Area Under Curve; Biomarkers; Child; Child, Preschool; Diagnosis, Different | 2012 |
Distinguishing bacterial from viral meningitis: the critical importance of the CSF lactic acid levels.
Topics: Diagnosis, Differential; Humans; Lactic Acid; Meningitis, Bacterial; Meningitis, Viral | 2006 |
[Lactate determination in the cerebrospinal fluid for differentiating bacterial and viral meningitis].
Topics: Bacterial Infections; Diagnosis, Differential; Humans; Lactates; Lactic Acid; Meningitis; Meningitis | 1984 |
[Lactate determination in the cerebrospinal fluid. Differential diagnostic significance].
Topics: Diagnosis, Differential; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Lactate | 1981 |
How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis?
Topics: Brain Diseases; Diagnosis, Differential; Humans; Lactates; Lactic Acid; Meningitis; Meningitis, Vira | 1983 |
Cerebrospinal fluid lactic acidosis in bacterial meningitis.
Topics: Acidosis; Adolescent; Bacterial Infections; Child; Child, Preschool; Humans; Infant; Infant, Newborn | 1981 |
[Assay of lactic acid in the cerebrospinal fluid for the diagnosis of bacterial meningitis. Strategies for the choice of discriminatory threshold].
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Diagnosis, Differential; Discriminant Analysis; Hum | 1997 |
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pr | 1997 |
Value of cerebrospinal fluid analysis in the differential diagnosis of meningitis: a study in 710 patients with suspected central nervous system infection.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Blood Glucose; C-Reactive Protein; Cerebrospinal Flui | 1988 |
[Significance of lactate level, lysozyme concentration and phosphohexose isomerase activity in the cerebrospinal fluid in the differential diagnosis of meningitis].
Topics: Bacterial Infections; Cryptococcosis; Diagnosis, Differential; Glucose-6-Phosphate Isomerase; Humans | 1985 |