lactic acid has been researched along with Meningitis, Tuberculous in 18 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bacterial meningitis and tubercular meningitis are still neurological emergencies characterized by severe mortality and morbidity." | 2.48 | [Revival of old diagnostic markers in the cerebrospinal fluid for the detection of infectious meningitis]. ( Sakushima, K; Sasaki, H; Yabe, I, 2012) |
| "Scrub typhus is one of the most common causes of meningo-encephalitis in endemic areas of the Indian subcontinent." | 1.62 | Is cerebrospinal fluid lactate useful in differentiating scrub typhus meningitis from aseptic, bacterial and tuberculous meningitis? ( Abhilash, KPP; Arora, S; Gunasekharan, K; Hazra, D; Mitra, S; Yesudass, P, 2021) |
| "TBM causes hydrocephalus, cerebral edema, increased intracranial pressure, global ischemia, and neurologic deficits, which disturb cellular metabolism and increase lactate levels." | 1.48 | Correlation of Lactate Concentration in Peripheral Plasma and Cerebrospinal Fluid with Glasgow Outcome Scale for Patients with Tuberculous Meningitis Complicated by Acute Hydrocephalus Treated with Fluid Diversions. ( Arief, G; Arifin, MZ; Faried, A; Nataprawira, HM, 2018) |
| "Diagnosis of tubercular meningitis (TBM) continues to be a clinical challenge and available microbiological tests fail to attain the required accuracy standards." | 1.48 | Cerebrospinal Fluid Lactate in Tubercular Meningitis: Diagnostic or Prognostic Marker? ( Fatma, J; Gupta, M; Karoli, R; Siddiqi, MS; Siddiqi, Z; Singhal, V, 2018) |
| "However, distinction between untreated pyogenic meningitis and virus meningitis is rarely problematic in clinical practice, so routine use of the test as an emergency procedure offers no extra advantage." | 1.27 | How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis? ( Dunbar, EM; Hooper, J; Mandal, BK; Parker, L, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| de Almeida, SM | 2 |
| Kussen, GB | 2 |
| Cogo, LL | 2 |
| Nogueira, K | 2 |
| Arora, S | 1 |
| Abhilash, KPP | 1 |
| Mitra, S | 1 |
| Hazra, D | 1 |
| Gunasekharan, K | 1 |
| Yesudass, P | 1 |
| Faried, A | 1 |
| Arief, G | 1 |
| Arifin, MZ | 1 |
| Nataprawira, HM | 1 |
| Siddiqi, Z | 1 |
| Siddiqi, MS | 1 |
| Fatma, J | 1 |
| Karoli, R | 1 |
| Singhal, V | 1 |
| Gupta, M | 1 |
| Mason, S | 1 |
| Reinecke, CJ | 1 |
| Kulik, W | 1 |
| van Cruchten, A | 1 |
| Solomons, R | 1 |
| van Furth, AM | 1 |
| Sakushima, K | 1 |
| Yabe, I | 1 |
| Sasaki, H | 1 |
| Chen, Z | 1 |
| Wang, Y | 1 |
| Zeng, A | 1 |
| Chen, L | 1 |
| Wu, R | 1 |
| Chen, B | 1 |
| Chen, M | 1 |
| Bo, J | 1 |
| Zhang, H | 1 |
| Peng, Q | 1 |
| Lu, J | 1 |
| Meng, QH | 1 |
| Alam, SM | 1 |
| Mitra, SK | 1 |
| Vajpeyi, GN | 1 |
| Chandra, R | 1 |
| Srivastava, DR | 1 |
| Sikka, KK | 1 |
| Govil, MK | 1 |
| Ruf, B | 1 |
| Mandal, BK | 1 |
| Dunbar, EM | 1 |
| Hooper, J | 1 |
| Parker, L | 1 |
| Guindi, S | 1 |
| Mansour, MM | 1 |
| Girgis, NI | 1 |
| Carlini, SM | 1 |
| Beyers, N | 1 |
| Schoeman, JF | 3 |
| Nel, ED | 1 |
| Truter, EJ | 1 |
| Donald, PR | 4 |
| Elshof, JW | 1 |
| Laubscher, JA | 1 |
| Janse van Rensburg, A | 1 |
| Van Zyl, L | 1 |
| Tang, LM | 1 |
| Lin, EX | 1 |
| Malan, C | 1 |
| Hornig, CR | 1 |
| Dorndorf, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Diagnosis and Treatment Monitoring of Native and Device-associated Meningitis Using D-lactate, a Pathogen-specific Diagnostic Biomarker in Cerebrospinal Fluid[NCT05146570] | 842 participants (Anticipated) | Interventional | 2021-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Meningitis, Tuberculous
| Article | Year |
|---|---|
[Revival of old diagnostic markers in the cerebrospinal fluid for the detection of infectious meningitis].
Topics: Adenosine Deaminase; Biomarkers; Humans; Lactic Acid; Meningitis, Bacterial; Practice Guidelines as | 2012 |
1 trial available for lactic acid and Meningitis, Tuberculous
| Article | Year |
|---|---|
The effect of adjuvant steroid treatment on serial cerebrospinal fluid changes in tuberculous meningitis.
Topics: Adenylate Kinase; Antitubercular Agents; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Drug | 2001 |
16 other studies available for lactic acid and Meningitis, Tuberculous
| Article | Year |
|---|---|
Cerebrospinal fluid lactate as a predictive biomarker for tuberculous meningitis diagnosis.
Topics: Humans; Lactic Acid; Mycobacterium tuberculosis; Retrospective Studies; ROC Curve; Tuberculosis, Men | 2023 |
Cerebrospinal fluid lactate as a predictive biomarker for tuberculous meningitis diagnosis.
Topics: Humans; Lactic Acid; Mycobacterium tuberculosis; Retrospective Studies; ROC Curve; Tuberculosis, Men | 2023 |
Cerebrospinal fluid lactate as a predictive biomarker for tuberculous meningitis diagnosis.
Topics: Humans; Lactic Acid; Mycobacterium tuberculosis; Retrospective Studies; ROC Curve; Tuberculosis, Men | 2023 |
Cerebrospinal fluid lactate as a predictive biomarker for tuberculous meningitis diagnosis.
Topics: Humans; Lactic Acid; Mycobacterium tuberculosis; Retrospective Studies; ROC Curve; Tuberculosis, Men | 2023 |
Is cerebrospinal fluid lactate useful in differentiating scrub typhus meningitis from aseptic, bacterial and tuberculous meningitis?
Topics: Adult; Cross-Sectional Studies; Diagnosis, Differential; Female; Humans; Lactic Acid; Male; Meningit | 2021 |
Correlation of Lactate Concentration in Peripheral Plasma and Cerebrospinal Fluid with Glasgow Outcome Scale for Patients with Tuberculous Meningitis Complicated by Acute Hydrocephalus Treated with Fluid Diversions.
Topics: Adolescent; Adult; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Cohort Studies; Female; Glas | 2018 |
Cerebrospinal Fluid Lactate in Tubercular Meningitis: Diagnostic or Prognostic Marker?
Topics: Adenosine Deaminase; Adolescent; Cerebrospinal Fluid; Cross-Sectional Studies; Humans; Lactic Acid; | 2018 |
Cerebrospinal fluid in tuberculous meningitis exhibits only the L-enantiomer of lactic acid.
Topics: Biomarkers; Cerebrospinal Fluid; Child; Child, Preschool; Chromatography, Liquid; Follow-Up Studies; | 2016 |
The clinical diagnostic significance of cerebrospinal fluid D-lactate for bacterial meningitis.
Topics: Adolescent; Adult; Aged; Area Under Curve; Biomarkers; Child; Child, Preschool; Diagnosis, Different | 2012 |
Prognostic evaluation of CSF lactic acid in cases of meningitis.
Topics: Humans; Lactates; Lactic Acid; Meningitis; Meningitis, Aseptic; Prognosis; Tuberculosis, Meningeal | 1984 |
[Lactate determination in the cerebrospinal fluid. Differential diagnostic significance].
Topics: Diagnosis, Differential; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Lactate | 1981 |
How useful is cerebrospinal fluid lactate estimation in differential diagnosis of meningitis?
Topics: Brain Diseases; Diagnosis, Differential; Humans; Lactates; Lactic Acid; Meningitis; Meningitis, Vira | 1983 |
Cerebrospinal fluid aldolase, lactate and creatine phosphokinase in the differential diagnosis of meningitis and meningo-encephalitis.
Topics: Adolescent; Adult; Child; Child, Preschool; Creatine Kinase; Diagnosis, Differential; Fructose-Bisph | 1982 |
Adenylate kinase activity in the cerebrospinal fluid of children with tuberculous meningitis and its relationship to neurological outcome.
Topics: Adenylate Kinase; Adolescent; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combinat | 1997 |
Cerebrospinal fluid lactate and raised intracranial pressure in tuberculous meningitis.
Topics: Humans; Infant; Intracranial Pressure; Lactates; Lactic Acid; Tuberculosis, Meningeal | 1989 |
Serial lactate determinations in tuberculous meningitis.
Topics: Adolescent; Adult; Aged; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mycobacterium tub | 1988 |
[Implication of CSF lactic acid determination in the differential diagnosis of tuberculous meningitis].
Topics: Diagnosis, Differential; Humans; Lactates; Lactic Acid; Tuberculosis, Meningeal | 1987 |
Cerebrospinal fluid lactate and lactate dehydrogenase levels as diagnostic aids in tuberculous meningitis.
Topics: Child; Child, Preschool; Humans; Infant; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Tuberculosi | 1985 |
[Significance of lactate level, lysozyme concentration and phosphohexose isomerase activity in the cerebrospinal fluid in the differential diagnosis of meningitis].
Topics: Bacterial Infections; Cryptococcosis; Diagnosis, Differential; Glucose-6-Phosphate Isomerase; Humans | 1985 |