lactic acid has been researched along with Medulloblastoma in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Excerpt | Relevance | Reference |
|---|---|---|
| " MRS (two patients with medulloblastoma and one with a SPNET), showed elevated choline, decreased N-acetyl aspartate, and a small taurine peak in all three patients." | 3.74 | Paediatric PNET: pre-surgical MRI features. ( Chawla, A; Emmanuel, JV; Lim, CC; Lou, J; Seow, WT; Teo, HE, 2007) |
| "Proton MRS of pediatric posterior fossa tumors seems to be helpful in prediction of tumor grading and histology." | 1.31 | [Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors]. ( Biegański, T; Kreisel, J; Liberski, PP; Nowosławska, E; Polis, L; Zakrzewski, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Magno, L | 1 |
| Manzi, D | 1 |
| D'Amico, D | 1 |
| Coni, S | 1 |
| Macone, A | 1 |
| Infante, P | 1 |
| Di Marcotullio, L | 1 |
| De Smaele, E | 1 |
| Ferretti, E | 1 |
| Screpanti, I | 1 |
| Agostinelli, E | 1 |
| Gulino, A | 1 |
| Canettieri, G | 1 |
| Chawla, A | 1 |
| Emmanuel, JV | 1 |
| Seow, WT | 1 |
| Lou, J | 1 |
| Teo, HE | 1 |
| Lim, CC | 1 |
| Zakrzewski, K | 1 |
| Kreisel, J | 1 |
| Polis, L | 1 |
| Nowosławska, E | 1 |
| Liberski, PP | 1 |
| Biegański, T | 1 |
3 other studies available for lactic acid and Medulloblastoma
| Article | Year |
|---|---|
Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Dichloroacetic Acid; Glyco | 2014 |
Paediatric PNET: pre-surgical MRI features.
Topics: Aspartic Acid; Cerebrospinal Fluid; Child; Child, Preschool; Choline; Creatine; Databases, Factual; | 2007 |
[Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors].
Topics: Adolescent; Aspartic Acid; Astrocytoma; Child; Child, Preschool; Choline; Creatine; Diagnosis, Diffe | 2001 |