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lactic acid and Lymph Node Metastasis

lactic acid has been researched along with Lymph Node Metastasis in 19 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"In the treatment of lung adenocarcinoma, targeting PFKFB3 would be a promising therapeutic strategy."1.48Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy. ( Ke, H; Li, X; Liu, J; Liu, Y; Qian, L; Tian, W; Yao, C; Zhang, J, 2018)
"Circadian clock dysregulation promotes cancer growth."1.43PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs. ( Chen, L; Huo, Y; Li, H; Tang, Q; Wu, C; Yu, R; Zhang, C; Zhao, J; Zhao, Y, 2016)
"As a means of treating lymphatic metastasis from lung cancer, the pharmacokinetics and therapeutic effects of an intrapleural (ipl) implantable drug delivery system consisting of a gelatin sponge impregnated with polylactide-co-glycolide paclitaxel (PLGA-PTX) microspheres were studied."1.35Translymphatic chemotherapy by intrapleural placement of gelatin sponge containing biodegradable Paclitaxel colloids controls lymphatic metastasis in lung cancer. ( Johnston, MR; Kwong, E; Liu, J; Meisner, D; Wu, XY, 2009)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's6 (31.58)29.6817
2010's11 (57.89)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
He, Y1
Yang, L1
Yuan, JJ1
Zhu, HH1
Shao, LY1
Li, X1
Liu, J2
Qian, L1
Ke, H1
Yao, C1
Tian, W1
Liu, Y1
Zhang, J1
Feng, C1
Gao, Y1
Wang, C5
Yu, X1
Zhang, W1
Guan, H1
Shan, Z1
Teng, W1
Clatot, F1
Gouérant, S1
Mareschal, S1
Cornic, M1
Berghian, A1
Choussy, O1
El Ouakif, F1
François, A1
Bénard, M1
Ruminy, P1
Picquenot, JM1
Jardin, F1
Tsujimoto, H1
Morimoto, Y1
Takahata, R1
Nomura, S1
Yoshida, K1
Hiraki, S1
Horiguchi, H1
Miyazaki, H1
Ono, S1
Saito, D1
Hara, I1
Ozeki, E1
Yamamoto, J1
Hase, K1
Vlachostergios, PJ1
Oikonomou, KG1
Gibilaro, E1
Apergis, G1
Chen, L1
Zhao, J1
Tang, Q1
Li, H1
Zhang, C1
Yu, R1
Zhao, Y1
Huo, Y1
Wu, C1
Martins, SF1
Amorim, R1
Viana-Pereira, M1
Pinheiro, C1
Costa, RF1
Silva, P1
Couto, C1
Alves, S1
Fernandes, S1
Vilaça, S1
Falcão, J1
Marques, H1
Pardal, F1
Rodrigues, M1
Preto, A1
Reis, RM1
Longatto-Filho, A1
Baltazar, F1
Meisner, D1
Kwong, E1
Wu, XY1
Johnston, MR1
Niu, C2
Wang, Z3
Zuo, G1
Krupka, TM2
Ran, H2
Zhang, P1
Li, P2
Chen, Y1
Chen, H1
Zheng, Y2
He, X1
Jia, R1
Xu, L1
Liang, K1
Shao, G1
Huang, P1
Li, W1
Hur, H1
Xuan, Y1
Kim, YB1
Lee, G1
Shim, W1
Yun, J1
Ham, IH1
Han, SU1
Lu, G1
Sun, Y1
You, Y1
Song, W1
Yang, K4
Wen, Y4
Li, L2
Hou, S1
Li, C1
Wang, X1
Star-Lack, J1
Spielman, D1
Adalsteinsson, E2
Kurhanewicz, J1
Terris, DJ2
Vigneron, DB1
Star-Lack, JM1
Adam, MF1
Pinto, HA1
Brown, JM1
Spielman, DM1

Trials

3 trials available for lactic acid and Lymph Node Metastasis

ArticleYear
Elevated lactic acid is a negative prognostic factor in metastatic lung cancer.
    Cancer biomarkers : section A of Disease markers, 2015, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Non-Sm

2015
[Clinical application of anticancer nanoparticles targeting metastasis foci of cervical lymph nodes in patients with oral carcinoma].
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2003, Volume: 21, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Chromatography, High Press

2003
In vivo 1H MR spectroscopy of human head and neck lymph node metastasis and comparison with oxygen tension measurements.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Choline; Creatine; Head and Neck Neoplasms; Humans; Lactic Ac

2000

Other Studies

16 other studies available for lactic acid and Lymph Node Metastasis

ArticleYear
[Effect of ultrasound contrast agent targeting gelatin on uptake of mouse ascites hepatocellular carcinoma cell lines with high lymphatic metastasis].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2020, Apr-23, Volume: 42, Issue:4

    Topics: Animals; Ascites; Carcinoma, Hepatocellular; Cell Line; Contrast Media; Diagnostic Imaging; Gelatin;

2020
Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy.
    Molecular and cellular biochemistry, 2018, Volume: 445, Issue:1-2

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Apoptosis; Bioma

2018
Aberrant overexpression of pyruvate kinase M2 is associated with aggressive tumor features and the BRAF mutation in papillary thyroid cancer.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:9

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Animals; Carcinoma, Papillary; Cell Line, Tumor; Ce

2013
The gene expression profile of inflammatory, hypoxic and metabolic genes predicts the metastatic spread of human head and neck squamous cell carcinoma.
    Oral oncology, 2014, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Carcinoma, Squamous Cell; Extracellular Matrix; Femal

2014
Theranostic Photosensitive Nanoparticles for Lymph Node Metastasis of Gastric Cancer.
    Annals of surgical oncology, 2015, Volume: 22 Suppl 3

    Topics: Adenocarcinoma; Animals; Apoptosis; Cell Proliferation; Coloring Agents; Drug Delivery Systems; Fluo

2015
PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs.
    Scientific reports, 2016, Apr-15, Volume: 6

    Topics: Adult; Apoptosis; Case-Control Studies; Cell Proliferation; Circadian Clocks; CLOCK Proteins; Female

2016
Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis.
    BMC cancer, 2016, 07-26, Volume: 16

    Topics: Basigin; Biomarkers, Tumor; Colorectal Neoplasms; Glucose Transporter Type 1; Glycolysis; Humans; Im

2016
Translymphatic chemotherapy by intrapleural placement of gelatin sponge containing biodegradable Paclitaxel colloids controls lymphatic metastasis in lung cancer.
    Cancer research, 2009, Feb-01, Volume: 69, Issue:3

    Topics: Absorption; Animals; Antineoplastic Agents, Phytogenic; Colloids; Delayed-Action Preparations; Femal

2009
Poly(Lactide-co-glycolide) ultrasonographic microbubbles carrying Sudan black for preoperative and intraoperative localization of lymph nodes.
    Clinical breast cancer, 2012, Volume: 12, Issue:3

    Topics: Animals; Azo Compounds; Cells, Cultured; Contrast Media; Drug Carriers; Intraoperative Period; Lacti

2012
³²P-chromic phosphate-Poly(L-Lactide) seeds of sustained release and their brachytherapy for prostate cancer with lymphatic metastasis.
    Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:7

    Topics: Animals; Brachytherapy; Cell Line, Tumor; Chromium Compounds; Humans; Lactic Acid; Lymphatic Metasta

2012
Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.
    International journal of oncology, 2013, Volume: 42, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Blotting, Western;

2013
Doxorubicin loaded superparamagnetic PLGA-iron oxide multifunctional microbubbles for dual-mode US/MR imaging and therapy of metastasis in lymph nodes.
    Biomaterials, 2013, Volume: 34, Issue:9

    Topics: Animals; Cell Line, Tumor; Contrast Media; Doxorubicin; Drug Delivery Systems; Lactic Acid; Lymph No

2013
[Preparation of cucurbitacinBE polylactic acid nano-particles for targeting cervical lymph nodes].
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2001, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Delayed-Action Preparations; Drug Delivery Systems;

2001
[Acute toxicity and local stimulate test of cucurbitacinBE polylactic acid nano-particles of targeting cervical lymph nodes].
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2001, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Female; Injections; Lactic Acid; Lethal Dose

2001
[The study of cucurbitacin BE polylactic acid nanoparticles delivering cucurbitacin BE to metastasized cervical lymph nodes in mice with oral cancer].
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2003, Volume: 21, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cucurbitacins; Delayed-Action

2003
In vivo lactate editing with simultaneous detection of choline, creatine, NAA, and lipid singlets at 1.5 T using PRESS excitation with applications to the study of brain and head and neck tumors.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 1998, Volume: 133, Issue:2

    Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactic Acid; Lip

1998