lactic acid has been researched along with Liver Steatosis in 24 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, in Himalayan marmots treated with AZT we observed delayed toxicity, including lactic acidosis, severe hepatic steatosis, obvious mitochondrial damage, and significant decreases in respiratory chain complex enzyme activity and mtDNA content." | 7.77 | Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus. ( Chen, H; Hu, M; Jiang, Z; Li, Z; Tao, Y; Xiong, Y; Zhang, L; Zhang, P, 2011) |
| "Addition of fructose to the diet of normal weight and overweight subjects can increase postprandial plasma triglyceride and uric acid concentration." | 5.24 | Metabolic Effects of Replacing Sugar-Sweetened Beverages with Artificially-Sweetened Beverages in Overweight Subjects with or without Hepatic Steatosis: A Randomized Control Clinical Trial. ( Boesch, C; Brandejsky, V; Campos, V; Despland, C; Kreis, R; Schneiter, P; Tappy, L, 2017) |
| "Clinical investigations suggest that hepatotoxicity after acetaminophen (APAP) overdose could be more severe in the context of obesity and nonalcoholic fatty liver disease." | 3.78 | Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice. ( Aubert, J; Begriche, K; Delannoy, M; Fromenty, B; Jaeschke, H; Lepage, S; Lucas-Clerc, C; McGill, MR; Morel, I; Pajaud, J; Ribault, C; Robin, MA; Turlin, B, 2012) |
| " In contrast, in Himalayan marmots treated with AZT we observed delayed toxicity, including lactic acidosis, severe hepatic steatosis, obvious mitochondrial damage, and significant decreases in respiratory chain complex enzyme activity and mtDNA content." | 3.77 | Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus. ( Chen, H; Hu, M; Jiang, Z; Li, Z; Tao, Y; Xiong, Y; Zhang, L; Zhang, P, 2011) |
| "steatosis grade 3 or steatohepatitis with or without beginning fibrosis frequently show altered fecal microbiota composition and elevated bacterial endotoxin levels." | 1.46 | Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children. ( Bergheim, I; Engstler, AJ; Maier, IB; Nier, A, 2017) |
| " PLGA exhibited excellent loading capacity for NUC with adjustable dosing ratios." | 1.46 | PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies. ( Gu, S; Li, X; Liu, G; Liu, Y; Mi, Y; Wu, X; Zhang, B, 2017) |
| "Fifty liver cirrhosis patients were enrolled into experimental group and 30 healthy people into control group." | 1.32 | Changes of plasma D(-)-lactate, diamine oxidase and endotoxin in patients with liver cirrhosis. ( Gong, ZJ; Ruan, P; Zhang, QR, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 14 (58.33) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, R | 3 |
| Chen, YN | 3 |
| Zhang, J | 3 |
| Liu, J | 3 |
| Raigani, S | 1 |
| Carroll, C | 1 |
| Griffith, S | 1 |
| Pendexter, C | 1 |
| Rosales, I | 1 |
| Deirawan, H | 1 |
| Beydoun, R | 1 |
| Yarmush, M | 1 |
| Uygun, K | 1 |
| Yeh, H | 1 |
| Nier, A | 1 |
| Engstler, AJ | 1 |
| Maier, IB | 1 |
| Bergheim, I | 1 |
| Carneiro, L | 1 |
| Asrih, M | 1 |
| Repond, C | 1 |
| Sempoux, C | 1 |
| Stehle, JC | 1 |
| Leloup, C | 1 |
| Jornayvaz, FR | 1 |
| Pellerin, L | 1 |
| Maeda Júnior, AS | 1 |
| Constantin, J | 1 |
| Utsunomiya, KS | 1 |
| Gilglioni, EH | 1 |
| Gasparin, FRS | 1 |
| Carreño, FO | 1 |
| de Moraes, SMF | 1 |
| Rocha, M | 1 |
| Natali, MRM | 1 |
| Ghizoni, CVC | 1 |
| Bracht, A | 1 |
| Ishii-Iwamoto, EL | 1 |
| Constantin, RP | 1 |
| Liu, L | 2 |
| Zhao, X | 1 |
| Wang, Q | 2 |
| Sun, X | 1 |
| Xia, L | 1 |
| Yang, B | 1 |
| Zhang, Y | 1 |
| Montgomery, S | 1 |
| Meng, H | 1 |
| Geng, T | 1 |
| Gong, D | 1 |
| Liu, Y | 1 |
| Wu, X | 1 |
| Mi, Y | 1 |
| Zhang, B | 1 |
| Gu, S | 1 |
| Liu, G | 1 |
| Li, X | 1 |
| Campos, V | 1 |
| Despland, C | 1 |
| Brandejsky, V | 1 |
| Kreis, R | 1 |
| Schneiter, P | 1 |
| Boesch, C | 1 |
| Tappy, L | 1 |
| Westbrook, RH | 1 |
| Yeoman, AD | 1 |
| Joshi, D | 1 |
| Heaton, ND | 1 |
| Quaglia, A | 1 |
| O'Grady, JG | 1 |
| Auzinger, G | 1 |
| Bernal, W | 1 |
| Heneghan, MA | 1 |
| Wendon, JA | 1 |
| Aschenbach, JR | 1 |
| Kristensen, NB | 1 |
| Donkin, SS | 1 |
| Hammon, HM | 1 |
| Penner, GB | 1 |
| Zhang, P | 2 |
| Zhang, L | 2 |
| Jiang, Z | 2 |
| Xiong, Y | 1 |
| Chen, H | 1 |
| Tao, Y | 1 |
| Hu, M | 1 |
| Li, Z | 1 |
| Li, H | 1 |
| Wang, L | 1 |
| Yan, X | 1 |
| Liu, Q | 1 |
| Yu, C | 1 |
| Wei, H | 1 |
| Li, Y | 1 |
| Zhang, X | 1 |
| He, F | 1 |
| Jiang, Y | 1 |
| Fu, Q | 1 |
| Huang, X | 1 |
| Shu, B | 1 |
| Xue, M | 1 |
| Wang, T | 1 |
| Aubert, J | 1 |
| Begriche, K | 1 |
| Delannoy, M | 1 |
| Morel, I | 1 |
| Pajaud, J | 1 |
| Ribault, C | 1 |
| Lepage, S | 1 |
| McGill, MR | 1 |
| Lucas-Clerc, C | 1 |
| Turlin, B | 1 |
| Robin, MA | 1 |
| Jaeschke, H | 1 |
| Fromenty, B | 1 |
| Botezelli, JD | 1 |
| Cambri, LT | 1 |
| Ghezzi, AC | 1 |
| Dalia, RA | 1 |
| Voltarelli, FA | 1 |
| de Mello, MA | 1 |
| Chan, IS | 1 |
| Guy, CD | 1 |
| Chen, Y | 1 |
| Lu, J | 1 |
| Swiderska-Syn, M | 1 |
| Michelotti, GA | 1 |
| Karaca, G | 1 |
| Xie, G | 1 |
| Krüger, L | 1 |
| Syn, WK | 1 |
| Anderson, BR | 1 |
| Pereira, TA | 1 |
| Choi, SS | 1 |
| Baldwin, AS | 1 |
| Diehl, AM | 1 |
| Lichterfeld, M | 1 |
| Fischer, HP | 1 |
| Spengler, U | 1 |
| Rockstroh, JK | 1 |
| DIANZANI, MU | 1 |
| Ruan, P | 1 |
| Gong, ZJ | 1 |
| Zhang, QR | 1 |
| Newberry, EP | 1 |
| Xie, Y | 1 |
| Kennedy, SM | 1 |
| Luo, J | 1 |
| Davidson, NO | 1 |
| Bannister, DW | 1 |
| O'Neill, IE | 1 |
| Whitehead, CC | 1 |
| Sewell, AC | 1 |
| Sperl, W | 1 |
| Herwig, J | 1 |
| Böhles, HJ | 1 |
| Hashimoto, T | 1 |
| Cook, WS | 1 |
| Qi, C | 1 |
| Yeldandi, AV | 1 |
| Reddy, JK | 1 |
| Rao, MS | 1 |
| Rémésy, C | 1 |
| Chilliard, Y | 1 |
| Rayssiguier, Y | 1 |
| Mazur, A | 1 |
| Demigné, C | 1 |
2 reviews available for lactic acid and Liver Steatosis
| Article | Year |
|---|---|
Gluconeogenesis in dairy cows: the secret of making sweet milk from sour dough.
Topics: Amino Acids; Animal Feed; Animals; Cattle; Fatty Liver; Female; Gene Expression Regulation; Gluconeo | 2010 |
[Liver metabolism of carbohydrates and lipids in ruminants: principal interaction during gestation and lactation].
Topics: Amino Acids; Animals; Artiodactyla; Carbohydrate Metabolism; Cattle; Cattle Diseases; Esterification | 1986 |
1 trial available for lactic acid and Liver Steatosis
| Article | Year |
|---|---|
Metabolic Effects of Replacing Sugar-Sweetened Beverages with Artificially-Sweetened Beverages in Overweight Subjects with or without Hepatic Steatosis: A Randomized Control Clinical Trial.
Topics: Adult; Blood Glucose; Body Mass Index; Diet; Fatty Acids, Nonesterified; Fatty Liver; Female; Glucag | 2017 |
21 other studies available for lactic acid and Liver Steatosis
| Article | Year |
|---|---|
Elevated serum levels of diamine oxidase, D-lactate and lipopolysaccharides are associated with metabolic-associated fatty liver disease.
Topics: Amine Oxidase (Copper-Containing); Fatty Liver; Humans; Lactic Acid; Lipopolysaccharides; Retrospect | 2023 |
Elevated serum levels of diamine oxidase, D-lactate and lipopolysaccharides are associated with metabolic-associated fatty liver disease.
Topics: Amine Oxidase (Copper-Containing); Fatty Liver; Humans; Lactic Acid; Lipopolysaccharides; Retrospect | 2023 |
Elevated serum levels of diamine oxidase, D-lactate and lipopolysaccharides are associated with metabolic-associated fatty liver disease.
Topics: Amine Oxidase (Copper-Containing); Fatty Liver; Humans; Lactic Acid; Lipopolysaccharides; Retrospect | 2023 |
Elevated serum levels of diamine oxidase, D-lactate and lipopolysaccharides are associated with metabolic-associated fatty liver disease.
Topics: Amine Oxidase (Copper-Containing); Fatty Liver; Humans; Lactic Acid; Lipopolysaccharides; Retrospect | 2023 |
Improvement of steatotic rat liver function with a defatting cocktail during ex situ normothermic machine perfusion is not directly related to liver fat content.
Topics: Animals; Bicarbonates; Cytokines; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; L | 2020 |
Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children.
Topics: Acute-Phase Proteins; Adolescent; Alanine Transaminase; Carrier Proteins; Child; Endotoxins; Fatty L | 2017 |
AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Fatty Liver; Haploinsufficiency; Lactic Acid; Lipid M | 2017 |
Cafeteria Diet Feeding in Young Rats Leads to Hepatic Steatosis and Increased Gluconeogenesis under Fatty Acids and Glucagon Influence.
Topics: Animals; Diet; Energy Intake; Fatty Acids; Fatty Liver; Feeding Behavior; Glucagon; Gluconeogenesis; | 2018 |
Prosteatotic and Protective Components in a Unique Model of Fatty Liver: Gut Microbiota and Suppressed Complement System.
Topics: Animals; Complement System Proteins; Fatty Liver; Gastrointestinal Microbiome; Geese; Gene Expressio | 2016 |
PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies.
Topics: Administration, Oral; Animals; Aporphines; Chemical Phenomena; Drug Delivery Systems; Fatty Liver; H | 2017 |
Outcomes of severe pregnancy-related liver disease: refining the role of transplantation.
Topics: Adult; Fatty Liver; Female; Humans; Hypertension, Pregnancy-Induced; Lactic Acid; Liver Diseases; Li | 2010 |
Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus.
Topics: Acidosis, Lactic; Animals; Antiviral Agents; Dideoxynucleosides; DNA, Mitochondrial; Fatty Liver; He | 2011 |
A proton nuclear magnetic resonance metabonomics approach for biomarker discovery in nonalcoholic fatty liver disease.
Topics: Adult; Animals; Biomarkers; Blood Glucose; Diet; Fatty Liver; Female; Glutamic Acid; Humans; Lactic | 2011 |
Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury.
Topics: Animals; Cell Respiration; Chemical and Drug Induced Liver Injury; Diterpenes; Epoxy Compounds; Fatt | 2011 |
Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.
Topics: 3-Hydroxybutyric Acid; Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P- | 2012 |
Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats.
Topics: Alanine Transaminase; Animals; Area Under Curve; Aspartate Aminotransferases; Blood Glucose; Catalas | 2012 |
Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Fatty Liver; Glycolysis; Hedgehog Proteins; Hep | 2012 |
[Fatty liver and increased serum lactate in a woman with HIV].
Topics: Abdominal Pain; Antiretroviral Therapy, Highly Active; Biopsy; Fatty Liver; Female; Hepatomegaly; HI | 2003 |
[Distribution of lactic acid oxidase in liver and kidney cells of normal rats and rats with fatty degeneration of the liver].
Topics: Adipose Tissue; Animals; Fatty Liver; Kidney; Lactic Acid; Liver; Oxidoreductases; Peroxidase; Perox | 1951 |
Changes of plasma D(-)-lactate, diamine oxidase and endotoxin in patients with liver cirrhosis.
Topics: Adolescent; Adult; Amine Oxidase (Copper-Containing); Analysis of Variance; Biomarkers; Case-Control | 2004 |
Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice.
Topics: Animals; Cholesterol, Dietary; Dietary Fats; Energy Intake; Enzymes; Fatty Acid Synthases; Fatty Aci | 2006 |
The post mortem diagnosis of fatal hypoglycaemia using the fatty liver and kidney syndrome of chicks as a model.
Topics: Animals; Biotin; Blood Glucose; Chickens; Fatty Liver; Glucose; Hypoglycemia; Kidney Diseases; Lacta | 1982 |
Cirrhosis in a child with deficiency of mitochondrial respiratory-chain succinate-cytochrome c-oxidoreductase.
Topics: Electron Transport Complex II; Electron Transport Complex III; Epilepsy, Tonic-Clonic; Fatal Outcome | 1997 |
Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting.
Topics: Animals; Fasting; Fatty Acids; Fatty Liver; Lactic Acid; Liver; Liver Glycogen; Mice; Mice, Inbred C | 2000 |