lactic acid has been researched along with Liver Dysfunction in 80 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of amrinone, a selective phosphodiesterase III inhibitor, on liver ischaemia reperfusion injury have not yet been clarified." | 9.09 | Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. ( Chang, K; Hanaoka, K; Hayashida, M; Makuuchi, M; Orii, R; Sugawara, Y; Takayama, T; Yamada, Y, 2000) |
| " With serum lactate values > 10 mmol/l 80 % of the patients die in intensive care, and if the severe lactic acidosis persists for 48 hours, all patients die." | 8.98 | [Lactic acidosis - update 2018]. ( de Heer, G; Fuhrmann, V; Jarczak, D; Kluge, S; Nierhaus, A, 2018) |
| "The fasting glucagon test of 40 patients with hepatic glycogen storage disease (type I, 13 patients; type Ib, 5 patients; type III, 12 patients; type IX (phosphorylase kinase deficiency), 10 patients) has been reviewed." | 7.66 | Value of the glucagon test in screening for hepatic glycogen storage disease. ( Dunger, DB; Leonard, JV, 1982) |
| "Hepatic ischemia was induced by temporary clamping of hepatic afferent blood vessels for 60 min with establishment of a portojugular bypass." | 5.29 | Protective effect of the calcium channel blocker diltiazem on hepatic function following warm ischemia. ( Aomatsu, Y; Fukuoka, T; Hisanaga, M; Horikawa, M; Kanehiro, H; Kido, K; Nakajima, Y; Taki, J; Wada, T; Yoshimura, A, 1993) |
| "The effects of amrinone, a selective phosphodiesterase III inhibitor, on liver ischaemia reperfusion injury have not yet been clarified." | 5.09 | Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. ( Chang, K; Hanaoka, K; Hayashida, M; Makuuchi, M; Orii, R; Sugawara, Y; Takayama, T; Yamada, Y, 2000) |
| " With serum lactate values > 10 mmol/l 80 % of the patients die in intensive care, and if the severe lactic acidosis persists for 48 hours, all patients die." | 4.98 | [Lactic acidosis - update 2018]. ( de Heer, G; Fuhrmann, V; Jarczak, D; Kluge, S; Nierhaus, A, 2018) |
| "The FDA approved 'label' for metformin lists hepatic insufficiency as a risk for lactic acidosis." | 3.96 | The safety and pharmacokinetics of metformin in patients with chronic liver disease. ( Braithwaite, HE; Carland, JE; Cheng, TS; Danta, M; Day, RO; Graham, GG; Greenfield, JR; Kumar, SS; Liu, Z; Smith, FC; Stocker, SL; Williams, KM, 2020) |
| " Correlation of findings with duration of hepatic pedicle clamping, postoperative markers of hepatocellular necrosis and function (aminotransferases, arterial lactate, international normalized ratio, bilirubin), and morbidity." | 3.83 | Mitochondrial bioenergetics and posthepatectomy liver dysfunction. ( Alexandrino, H; Castro E Sousa, F; Martins, MA; Palmeira, CM; Rolo, AP; Teodoro, JS; Tralhão, JG; Varela, AT, 2016) |
| "Increased brain lactate, and not glutamine, is a primary player in the pathogenesis of brain edema in CLD." | 3.80 | Increased brain lactate is central to the development of brain edema in rats with chronic liver disease. ( Bosoi, CR; Huynh, J; Marin, H; Parent-Robitaille, C; Rose, CF; Tremblay, M; Zwingmann, C, 2014) |
| " Lactic acidosis, characterized by metabolic acidosis, blood lactate above 5 mmol/l, hepatic steatosis and high mortality, represents the extreme end of this spectrum where there is complete decompensation." | 3.71 | Hyperlactatemia syndromes in people with HIV infection. ( John, M; Mallal, S, 2002) |
| "The mechanism of prolongation of sleeping (anesthesia) time after phenobarbital (PB) treatment was assessed in mice with ethionine (ET)-induced liver disorders (ET-treated group)." | 3.69 | Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice. ( Kawai, Y; Noguchi, M, 1996) |
| "The effects of hyperammonemia on brain function have been studied in three different experimental models in the rat: acute liver ischemia, urease-treated animals and methionine sulfoximine-treated animals." | 3.68 | Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation. ( Bosman, DK; Bovée, WM; Chamuleau, RA; De Graaf, AA; Deutz, NE; Jörning, GG; Maas, MA; Van Eijk, HM; vd Hulst, RW, 1990) |
| "The fasting glucagon test of 40 patients with hepatic glycogen storage disease (type I, 13 patients; type Ib, 5 patients; type III, 12 patients; type IX (phosphorylase kinase deficiency), 10 patients) has been reviewed." | 3.66 | Value of the glucagon test in screening for hepatic glycogen storage disease. ( Dunger, DB; Leonard, JV, 1982) |
| "Of 770 patients with severe sepsis or septic shock, 208 (27%) with hepatic dysfunction were included in the analysis." | 1.43 | Lactate clearance and mortality in septic patients with hepatic dysfunction. ( Chung, CR; Ha, TS; Hwang, SY; Jeon, K; Jo, IJ; Shin, TG; Suh, GY, 2016) |
| "Patients with a final diagnosis of septic shock requiring vasopressors were divided, based on initial lactate, to nonlactate expressors (0-2." | 1.38 | Prevalence and characteristics of nonlactate and lactate expressors in septic shock. ( Cocchi, MN; Donnino, MW; Dugas, AF; Gautam, S; Mackenhauer, J; Salciccioli, JD, 2012) |
| "Of 307 patients with septic shock, 118 (38%) patients with hepatic dysfunction were eligible for this study." | 1.37 | Initial lactate level and mortality in septic shock patients with hepatic dysfunction. ( Chung, MP; Jeon, K; Kang, YR; Kim, H; Koh, WJ; Kwon, OJ; Suh, GY; Um, SW, 2011) |
| "Hepatic ischemia was induced by temporary clamping of hepatic afferent blood vessels for 60 min with establishment of a portojugular bypass." | 1.29 | Protective effect of the calcium channel blocker diltiazem on hepatic function following warm ischemia. ( Aomatsu, Y; Fukuoka, T; Hisanaga, M; Horikawa, M; Kanehiro, H; Kido, K; Nakajima, Y; Taki, J; Wada, T; Yoshimura, A, 1993) |
| " The inclusion of a dosed physical training in the therapy and rehabilitation programme, respectively, of patients with chronic liver diseases can be recommended, particularly, since there is no causal medicamentous therapy of chronic liver diseases possible at present." | 1.27 | [Effect of physical training on the aerobic-anaerobic transition in chronic liver diseases]. ( Buhl, H; Krause, P; Rogos, R, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (30.00) | 18.7374 |
| 1990's | 14 (17.50) | 18.2507 |
| 2000's | 10 (12.50) | 29.6817 |
| 2010's | 25 (31.25) | 24.3611 |
| 2020's | 7 (8.75) | 2.80 |
| Authors | Studies |
|---|---|
| Schurink, IJ | 1 |
| de Haan, JE | 1 |
| Willemse, J | 1 |
| Mueller, M | 1 |
| Doukas, M | 1 |
| Roest, H | 1 |
| de Goeij, FHC | 1 |
| Polak, WG | 1 |
| Ijzermans, JNM | 1 |
| Dutkowski, P | 1 |
| van der Laan, LJW | 1 |
| de Jonge, J | 1 |
| Simicic, D | 1 |
| Rackayova, V | 1 |
| Braissant, O | 1 |
| Toso, C | 1 |
| Oldani, G | 1 |
| Sessa, D | 1 |
| McLin, VA | 1 |
| Cudalbu, C | 1 |
| Ogura, A | 1 |
| Tsurumi, A | 1 |
| Que, YA | 1 |
| Almpani, M | 1 |
| Zheng, H | 1 |
| Tompkins, RG | 1 |
| Ryan, CM | 1 |
| Rahme, LG | 1 |
| Smith, FC | 1 |
| Stocker, SL | 1 |
| Danta, M | 1 |
| Carland, JE | 1 |
| Kumar, SS | 1 |
| Liu, Z | 1 |
| Greenfield, JR | 1 |
| Braithwaite, HE | 1 |
| Cheng, TS | 1 |
| Graham, GG | 1 |
| Williams, KM | 1 |
| Day, RO | 1 |
| Singh, S | 1 |
| Verma, N | 1 |
| Singh, V | 1 |
| Chaudhary, K | 1 |
| Vaid, A | 1 |
| Duffy, Á | 1 |
| Paranjpe, I | 1 |
| Jaladanki, S | 1 |
| Paranjpe, M | 1 |
| Johnson, K | 1 |
| Gokhale, A | 1 |
| Pattharanitima, P | 1 |
| Chauhan, K | 1 |
| O'Hagan, R | 1 |
| Van Vleck, T | 1 |
| Coca, SG | 1 |
| Cooper, R | 1 |
| Glicksberg, B | 1 |
| Bottinger, EP | 1 |
| Chan, L | 1 |
| Nadkarni, GN | 1 |
| Rha, MS | 1 |
| Han, JW | 1 |
| Koh, JY | 1 |
| Lee, HS | 1 |
| Kim, JH | 1 |
| Cho, K | 1 |
| Kim, SI | 1 |
| Kim, MS | 1 |
| Lee, JG | 1 |
| Park, SH | 1 |
| Joo, DJ | 1 |
| Park, JY | 1 |
| Shin, EC | 1 |
| Hernandez, G | 2 |
| Bellomo, R | 1 |
| Bakker, J | 2 |
| Kluge, S | 1 |
| de Heer, G | 1 |
| Jarczak, D | 1 |
| Nierhaus, A | 1 |
| Fuhrmann, V | 1 |
| Kjaergaard, U | 1 |
| Laustsen, C | 1 |
| Nørlinger, T | 1 |
| Tougaard, RS | 1 |
| Mikkelsen, E | 1 |
| Qi, H | 1 |
| Bertelsen, LB | 1 |
| Jessen, N | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Regan, JA | 1 |
| Golubski, B | 1 |
| Gilbert, EB | 1 |
| Sullivan, B | 1 |
| McCall, SJ | 1 |
| Sata, SS | 1 |
| Jeppesen, JB | 1 |
| Mortensen, C | 1 |
| Bendtsen, F | 1 |
| Møller, S | 1 |
| Meguro, M | 1 |
| Mizuguchi, T | 1 |
| Kawamoto, M | 1 |
| Nakamura, Y | 1 |
| Ota, S | 1 |
| Kukita, K | 1 |
| Ishii, M | 1 |
| Tatsumi, H | 1 |
| Hirata, K | 1 |
| Oria, M | 1 |
| Jalan, R | 1 |
| Bosoi, CR | 2 |
| Zwingmann, C | 1 |
| Marin, H | 1 |
| Parent-Robitaille, C | 1 |
| Huynh, J | 1 |
| Tremblay, M | 1 |
| Rose, CF | 2 |
| Al-Freah, MA | 1 |
| Gera, A | 1 |
| Martini, S | 1 |
| McPhail, MJ | 1 |
| Devlin, J | 1 |
| Harrison, PM | 1 |
| Shawcross, D | 1 |
| Abeles, RD | 1 |
| Taylor, NJ | 1 |
| Auzinger, G | 2 |
| Bernal, W | 2 |
| Heneghan, MA | 2 |
| Wendon, JA | 2 |
| Riediger, C | 1 |
| Mueller, MW | 1 |
| Hapfelmeier, A | 1 |
| Bachmann, J | 1 |
| Friess, H | 1 |
| Kleeff, J | 1 |
| Tapia, P | 1 |
| Soto, D | 1 |
| Bruhn, A | 1 |
| Alegría, L | 1 |
| Jarufe, N | 1 |
| Luengo, C | 1 |
| Kattan, E | 1 |
| Regueira, T | 1 |
| Meissner, A | 1 |
| Menchaca, R | 1 |
| Vives, MI | 1 |
| Echeverría, N | 1 |
| Ospina-Tascón, G | 1 |
| Corrêa, TD | 1 |
| Takala, J | 1 |
| Jakob, SM | 1 |
| Ha, TS | 1 |
| Shin, TG | 1 |
| Jo, IJ | 1 |
| Hwang, SY | 1 |
| Chung, CR | 1 |
| Suh, GY | 2 |
| Jeon, K | 2 |
| Alexandrino, H | 1 |
| Varela, AT | 1 |
| Teodoro, JS | 1 |
| Martins, MA | 1 |
| Rolo, AP | 1 |
| Tralhão, JG | 1 |
| Palmeira, CM | 1 |
| Castro E Sousa, F | 1 |
| Fisher, J | 1 |
| Douglas, JJ | 1 |
| Linder, A | 1 |
| Boyd, JH | 1 |
| Walley, KR | 1 |
| Russell, JA | 1 |
| Xia, S | 1 |
| Chen, G | 1 |
| Wang, B | 1 |
| Yin, Y | 1 |
| Sun, Z | 1 |
| Zhao, J | 1 |
| Li, P | 1 |
| Zhao, L | 1 |
| Zhou, H | 1 |
| Sellars, EA | 1 |
| Balmakund, T | 1 |
| Bosanko, K | 1 |
| Nichols, BL | 1 |
| Kahler, SG | 1 |
| Zarate, YA | 1 |
| Ferrando-Vivas, P | 1 |
| Jones, A | 1 |
| Rowan, KM | 1 |
| Harrison, DA | 1 |
| Li, Y | 1 |
| Mei, L | 1 |
| Qiang, J | 1 |
| Ju, S | 1 |
| Zhao, S | 1 |
| Lei, R | 1 |
| Wu, C | 1 |
| Yang, B | 1 |
| Ma, H | 1 |
| Shi, C | 1 |
| Wang, Q | 2 |
| Yuan, Y | 1 |
| Liao, M | 1 |
| Bengmark, S | 1 |
| Kato, M | 1 |
| Sawada, T | 1 |
| Kita, J | 1 |
| Shimoda, M | 1 |
| Kubota, K | 1 |
| Westbrook, RH | 1 |
| Yeoman, AD | 1 |
| Joshi, D | 1 |
| Heaton, ND | 1 |
| Quaglia, A | 1 |
| O'Grady, JG | 1 |
| Ho, KM | 1 |
| Kang, YR | 1 |
| Um, SW | 1 |
| Koh, WJ | 1 |
| Chung, MP | 1 |
| Kim, H | 1 |
| Kwon, OJ | 1 |
| Dugas, AF | 1 |
| Mackenhauer, J | 1 |
| Salciccioli, JD | 1 |
| Cocchi, MN | 1 |
| Gautam, S | 1 |
| Donnino, MW | 1 |
| CASTALDI, D | 1 |
| AVANZINI, M | 1 |
| NALEBUFF, DJ | 3 |
| WINTERNITZ, WW | 3 |
| MONTENERO, P | 1 |
| COLLETTI, A | 1 |
| FABBRI, G | 1 |
| HORN, HD | 1 |
| AMELUNG, D | 1 |
| WIEME, RJ | 2 |
| DEMEULENAERE, L | 2 |
| FERSINI, C | 1 |
| RIPA, R | 1 |
| SBRIGHI, V | 1 |
| CHOI, KW | 1 |
| GANDARA, M | 1 |
| FOSTER, RF | 1 |
| NEVE, RA | 1 |
| APAYDIN, KS | 1 |
| SCHNEIDERBAUR, A | 1 |
| RETTENBACHER, F | 1 |
| Marko, P | 1 |
| Gabrielli, A | 1 |
| Caruso, LJ | 1 |
| Jeschke, MG | 1 |
| Rensing, H | 1 |
| Klein, D | 1 |
| Schubert, T | 1 |
| Mautes, AE | 1 |
| Bolder, U | 1 |
| Croner, RS | 1 |
| Hong, SB | 1 |
| Furihata, M | 1 |
| Baba, M | 1 |
| Zbar, B | 1 |
| Schmidt, LS | 1 |
| Higuchi, S | 1 |
| Wu, R | 1 |
| Zhou, M | 1 |
| Ravikumar, TS | 1 |
| Wang, P | 1 |
| Liao, P | 1 |
| Wei, L | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Wu, H | 1 |
| Wu, Y | 1 |
| Ni, J | 1 |
| Pei, F | 1 |
| Funk, GC | 1 |
| Goodkin, DA | 1 |
| Krishna, GG | 1 |
| Narins, RG | 1 |
| Dunger, DB | 1 |
| Leonard, JV | 1 |
| Alberti, KG | 1 |
| Johnston, DG | 1 |
| Piniewska-Hulas, M | 1 |
| Whittaker, J | 1 |
| Connor, H | 1 |
| Woods, HF | 1 |
| Murray, JD | 1 |
| Ledingham, JG | 1 |
| Record, CO | 1 |
| Chase, RA | 1 |
| Williams, R | 3 |
| Appleton, D | 1 |
| Mokuda, O | 1 |
| Ubukata, E | 1 |
| Sakamoto, Y | 1 |
| Takano, H | 1 |
| Matsuda, H | 1 |
| Kadoba, K | 1 |
| Kawata, H | 1 |
| Sawa, Y | 1 |
| Shimazaki, Y | 1 |
| Taenaka, N | 1 |
| Nagamine, T | 1 |
| Saito, S | 1 |
| Yamada, S | 1 |
| Arai, T | 2 |
| Takehara, K | 1 |
| Fukui, T | 1 |
| Hisanaga, M | 1 |
| Nakajima, Y | 1 |
| Wada, T | 1 |
| Kanehiro, H | 1 |
| Fukuoka, T | 1 |
| Horikawa, M | 1 |
| Yoshimura, A | 1 |
| Kido, K | 1 |
| Taki, J | 1 |
| Aomatsu, Y | 1 |
| Noguchi, M | 1 |
| Kawai, Y | 1 |
| Douzinas, EE | 1 |
| Tsidemiadou, PD | 1 |
| Pitaridis, MT | 1 |
| Andrianakis, I | 1 |
| Bobota-Chloraki, A | 1 |
| Katsouyanni, K | 1 |
| Sfyras, D | 1 |
| Malagari, K | 1 |
| Roussos, C | 1 |
| Tayasu, E | 1 |
| Nishijima, T | 1 |
| Nishina, M | 1 |
| Fujiwara, K | 1 |
| De Jonghe, B | 1 |
| Cheval, C | 1 |
| Misset, B | 1 |
| Timsit, JF | 1 |
| Garrouste, M | 1 |
| Montuclard, L | 1 |
| Carlet, J | 1 |
| Morris, AA | 1 |
| Orii, R | 1 |
| Sugawara, Y | 1 |
| Hayashida, M | 1 |
| Yamada, Y | 1 |
| Chang, K | 1 |
| Takayama, T | 1 |
| Makuuchi, M | 1 |
| Hanaoka, K | 1 |
| John, M | 1 |
| Mallal, S | 1 |
| Munnich, A | 1 |
| Rustin, P | 1 |
| Rötig, A | 1 |
| Chretien, D | 1 |
| Bonnefont, JP | 1 |
| Nuttin, C | 1 |
| Cormier, V | 1 |
| Vassault, A | 1 |
| Parvy, P | 1 |
| Bardet, J | 1 |
| Schlichtig, R | 1 |
| Klions, HA | 1 |
| Kramer, DJ | 1 |
| Nemoto, EM | 1 |
| Bosman, DK | 1 |
| Deutz, NE | 1 |
| De Graaf, AA | 1 |
| vd Hulst, RW | 1 |
| Van Eijk, HM | 1 |
| Bovée, WM | 1 |
| Maas, MA | 1 |
| Jörning, GG | 1 |
| Chamuleau, RA | 1 |
| Davenport, A | 1 |
| Will, EJ | 1 |
| Davison, AM | 1 |
| Bates, TE | 1 |
| Williams, SR | 1 |
| Kauppinen, RA | 1 |
| Gadian, DG | 1 |
| Kawachi, M | 1 |
| Kono, N | 1 |
| Tarui, S | 1 |
| Krause, P | 1 |
| Buhl, H | 1 |
| Rogos, R | 1 |
| Takagi, D | 1 |
| Takeyama, N | 1 |
| Tanaka, T | 1 |
| Guerin, JM | 1 |
| Meyer, P | 1 |
| Segrestaa, JM | 1 |
| Bihari, DJ | 1 |
| Gimson, AE | 2 |
| Bihari, D | 1 |
| Lindridge, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients: Pathophysiological Determinants, and Relation to Changes in Systemic, Regional and Microcirculatory Blood Flow[NCT04693923] | 42 participants (Anticipated) | Interventional | 2021-02-01 | Not yet recruiting | |||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| Early Goal Directed Therapy Using a Physiological Holistic View. A Multicenter Study in Latin America: The ANDROMEDA-SHOCK Study[NCT03078712] | 424 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Lactate Clearance and Mortality in Patients With Severe Sepsis and Septic Shock: Comparison by Hepatic Dysfunction[NCT01709565] | 245 participants (Anticipated) | Observational | 2012-07-31 | Recruiting | |||
| Comparative Analysis Between Ringer's Lactate vs Acetate Containing Balanced Crystalloid Solution (Plasma Lyte-A) as Cardiopulmonary Bypass Prime[NCT03043131] | Phase 3 | 60 participants (Anticipated) | Interventional | 2017-02-10 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for lactic acid and Liver Dysfunction
| Article | Year |
|---|---|
[Lactic acidosis - update 2018].
Topics: Acidosis, Lactic; Critical Care; Humans; Lactic Acid; Liver Diseases; Metabolic Clearance Rate; Prog | 2018 |
Elevated cerebral lactate: Implications in the pathogenesis of hepatic encephalopathy.
Topics: Ammonia; Animals; Brain; Brain Edema; Citric Acid Cycle; Dichloroacetic Acid; Drug Evaluation, Precl | 2014 |
Bio-ecological control of chronic liver disease and encephalopathy.
Topics: Dietary Proteins; Feeding Behavior; Food, Formulated; Hepatic Encephalopathy; Humans; Inflammation; | 2009 |
[Stewart's acid-base approach].
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Anions; Bicarbonates; Cations; Diabetic Ketoacidosis; El | 2007 |
Disturbances of metabolic homeostasis is liver disease.
Topics: Fasting; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Growth Hormone; Homeostasis; Humans; Hyd | 1981 |
Mitochondrial respiratory chain disorders and the liver.
Topics: Diffuse Cerebral Sclerosis of Schilder; DNA, Mitochondrial; Electron Transport; Humans; Hypoglycemia | 1999 |
Cardiovascular, pulmonary and renal complications of fulminant hepatic failure.
Topics: Biological Transport; Cardiovascular Diseases; Epoprostenol; Hemodynamics; Hemoglobins; Humans; Kidn | 1986 |
2 trials available for lactic acid and Liver Dysfunction
| Article | Year |
|---|---|
Erythropoietin ameliorates early ischemia-reperfusion injury following the Pringle maneuver.
Topics: Aged; Animals; Digestive System Surgical Procedures; Erythropoietin; Female; Hematocrit; Hemoglobins | 2010 |
Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1.
Topics: Aged; Alprostadil; Amrinone; Analysis of Variance; Female; Hepatectomy; Humans; Indocyanine Green; L | 2000 |
71 other studies available for lactic acid and Liver Dysfunction
| Article | Year |
|---|---|
A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion.
Topics: Adult; Aged; Cold Ischemia; Cytochrome P-450 CYP1A2; Graft Survival; Humans; Lactic Acid; Liver; Liv | 2021 |
Neurometabolic changes in a rat pup model of type C hepatic encephalopathy depend on age at liver disease onset.
Topics: Adult; Animals; Brain; Child; Glutamine; Hepatic Encephalopathy; Humans; Lactic Acid; Liver Diseases | 2023 |
Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients.
Topics: Adult; Age Factors; Area Under Curve; Body Surface Area; Burns; Comorbidity; Debridement; Diabetes M | 2019 |
The safety and pharmacokinetics of metformin in patients with chronic liver disease.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Chronic Disease; Comorbidity; Cross-Sectional Stud | 2020 |
Letter to the Editor: MELD-Lactate-the New Kid on the Block.
Topics: End Stage Liver Disease; Humans; Inpatients; Lactic Acid; Liver Diseases; Severity of Illness Index | 2020 |
Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.
Topics: Acute Kidney Injury; Aged; Alanine Transaminase; Bilirubin; Blood Urea Nitrogen; Comorbidity; Creati | 2020 |
Impaired antibacterial response of liver sinusoidal Vγ9
Topics: Case-Control Studies; Chronic Disease; Endotoxins; Escherichia coli; Female; Humans; Lactic Acid; Li | 2022 |
The ten pitfalls of lactate clearance in sepsis.
Topics: Humans; Lactic Acid; Liver Diseases; Metabolic Clearance Rate; Sepsis | 2019 |
Hyperpolarized [1-
Topics: Alanine; Animals; Blood Glucose; Citric Acid Cycle; Fatty Acids; Female; Glucagon; Insulin; Lactic A | 2018 |
Glycogenic Hepatopathy Causing Elevated Lactic Acid and Liver Enzymes.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Glucose; Diabetes Mel | 2020 |
Lactate metabolism in chronic liver disease.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Chronic Disease; Fasting; Female; Femoral Artery; Gal | 2013 |
Continuous monitoring of central venous oxygen saturation predicts postoperative liver dysfunction after liver resection.
Topics: Adult; Aged; Aged, 80 and over; Blood Transfusion; Female; Hepatectomy; Humans; Lactic Acid; Liver D | 2013 |
Brain lactate in hepatic encephalopathy: friend or foe?
Topics: Animals; Brain; Brain Edema; Hepatic Encephalopathy; Lactic Acid; Liver Diseases; Male | 2014 |
Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.
Topics: Ammonia; Animals; Brain; Brain Edema; Chronic Disease; Glutamine; Hepatic Encephalopathy; Lactic Aci | 2014 |
Comparison of scoring systems and outcome of patients admitted to a liver intensive care unit of a tertiary referral centre with severe variceal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Critical Illness; Esophageal and Gastric Varices | 2014 |
Preoperative Serum Bilirubin and Lactate Levels Predict Postoperative Morbidity and Mortality in Liver Surgery: A Single-Center Evaluation.
Topics: Adult; Aged; Aged, 80 and over; Bilirubin; Cohort Studies; Female; Hepatectomy; Humans; Lactic Acid; | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Is lactate clearance impaired in septic shock?
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver Diseases; Metabolic Clearance Rate; Shock | 2015 |
Lactate clearance and mortality in septic patients with hepatic dysfunction.
Topics: Aged; Female; Hospital Mortality; Humans; Lactic Acid; Liver Diseases; Logistic Models; Male; Middle | 2016 |
Mitochondrial bioenergetics and posthepatectomy liver dysfunction.
Topics: Adenoma; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Ami | 2016 |
Elevated Plasma Angiopoietin-2 Levels Are Associated With Fluid Overload, Organ Dysfunction, and Mortality in Human Septic Shock.
Topics: Acute Kidney Injury; Angiopoietin-2; Australia; Biomarkers; Blood Coagulation Disorders; Canada; Coh | 2016 |
Addition of Sodium Pyruvate to Stored Red Blood Cells Attenuates Liver Injury in a Murine Transfusion Model.
Topics: Animals; Blood Preservation; Blood Transfusion; Disease Models, Animal; Erythrocytes; Hemoglobins; H | 2016 |
Severe Metabolic Acidosis and Hepatopathy due to Leukoencephalopathy with Thalamus and Brainstem Involvement and High Lactate.
Topics: Acidosis; Brain Stem; Diagnosis, Differential; Glutamate-tRNA Ligase; Humans; Infant; Lactic Acid; L | 2017 |
Development and validation of the new ICNARC model for prediction of acute hospital mortality in adult critical care.
Topics: Adult; Age Factors; Aged; Blood Glucose; Cardiopulmonary Resuscitation; Chronic Disease; Creatinine; | 2017 |
Magnetic Resonance Spectroscopy for Evaluating Portal-Systemic Encephalopathy in Patients with Chronic Hepatic Schistosomiasis Japonicum.
Topics: Aged; Aged, 80 and over; Ammonia; Brain; Chronic Disease; Female; Globus Pallidus; Glutamine; Hepati | 2016 |
Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: a rapid in vivo screening method for nanotoxicity.
Topics: Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Copper; Drug Evaluation, | 2008 |
Outcomes of severe pregnancy-related liver disease: refining the role of transplantation.
Topics: Adult; Fatty Liver; Female; Humans; Hypertension, Pregnancy-Induced; Lactic Acid; Liver Diseases; Li | 2010 |
Ten commandments of interpreting and applying results of biomarker research.
Topics: C-Reactive Protein; Female; Humans; Lactic Acid; Liver Diseases; Male; Shock, Septic | 2011 |
Initial lactate level and mortality in septic shock patients with hepatic dysfunction.
Topics: Aged; Female; Hospital Mortality; Humans; Lactic Acid; Liver Diseases; Male; Middle Aged; Odds Ratio | 2011 |
Prevalence and characteristics of nonlactate and lactate expressors in septic shock.
Topics: Aged; Aged, 80 and over; Bacteremia; Comorbidity; Emergency Service, Hospital; Female; Hospitals, Un | 2012 |
[Lactic acid in the blood of liver disease subjects and variations caused by triphosphoric esters of aneurin].
Topics: Blood; Esters; Humans; Lactic Acid; Liver Diseases; Thiamine | 1953 |
Lactic acid response to epinephrine in experimental liver disease.
Topics: Blood; Epinephrine; Humans; Lactic Acid; Liver Diseases | 1956 |
[Studies on double curves of glycemia, pyruvemia and lactacidemia in patients with liver diseases after intravenous administration of glucose].
Topics: Administration, Intravenous; Blood; Blood Glucose; Glucose; Glucose Tolerance Test; Humans; Lactic A | 1956 |
Lactic acid response to epinephrine in experimental liver disease: a review.
Topics: Epinephrine; Humans; Lactic Acid; Liver Diseases | 1956 |
Lactic acid response to epinephrine in experimental liver disease: a review.
Topics: Epinephrine; Humans; Lactic Acid; Liver Diseases | 1956 |
Lactic acid response to epinephrine in experimental liver disease: a review.
Topics: Epinephrine; Humans; Lactic Acid; Liver Diseases | 1956 |
Lactic acid response to epinephrine in experimental liver disease: a review.
Topics: Epinephrine; Humans; Lactic Acid; Liver Diseases | 1956 |
[Value of determination of serum transaminases & lactic acid dehydrogenase in liver diseases].
Topics: Humans; Lactic Acid; Liver Diseases; Liver Function Tests; Oxidoreductases; Transaminases; Vascular | 1957 |
[Enzymo-electrophoresis of lactic acid dehydrogenase; selective test of parenchymatous unimpaired state].
Topics: Electrophoresis; Lactic Acid; Liver Diseases; Oxidoreductases | 1959 |
[The value of enzymo-electrophoresis of the dehydrogenase of lactic acid in hepatology].
Topics: Electrophoresis; Gastroenterology; Lactate Dehydrogenases; Lactic Acid; Liver Diseases; Oxidoreducta | 1959 |
[The action of DOCA on the arteriovenous blood sugar-pyruvic-alcohol-lactic acid sequence in liver patients].
Topics: Blood Chemical Analysis; Blood Glucose; Carbohydrate Metabolism; Desoxycorticosterone; Desoxycortico | 1962 |
[The blood pyruvic and lactic acid levels in patients with liver disease, and changes following the administration of thioctic acid].
Topics: Humans; Lactates; Lactic Acid; Liver Diseases; Pyruvates; Thioctic Acid | 1963 |
[SERUM ENZYMES IN THE DIAGNOSIS OF LIVER DISEASE. IV. MALATE DEHYDROGENASE, LACTATE METABOLITES AND OTHER ENZYMES].
Topics: Aminopeptidases; Enzymes; Humans; L-Lactate Dehydrogenase; Lactic Acid; Liver Diseases; Malate Dehyd | 1963 |
CLINICAL EXPERIENCE WITH SERUM GLUTAMIC OXALOACETIC ACID TRANSAMINASE AND LACTIC ACID DEHYDROGENASE ASSAYS.
Topics: Aspartate Aminotransferases; Blood Chemical Analysis; Clinical Enzyme Tests; Diagnosis, Differential | 1964 |
[The behavior of lactic acid dehydrogenase in parenchymal liver diseases and obstructive jaundice].
Topics: Jaundice; Jaundice, Obstructive; Lactate Dehydrogenases; Lactic Acid; Liver Diseases; Oxidoreductase | 1959 |
Too much lactate or too little liver?
Topics: Acidosis, Lactic; Adenosine Triphosphate; Aged; Female; Hemofiltration; Humans; Lactic Acid; Liver; | 2004 |
Insulin prevents liver damage and preserves liver function in lipopolysaccharide-induced endotoxemic rats.
Topics: Acute-Phase Proteins; Adenosine Triphosphate; Animals; Apoptosis; Blood Glucose; Caspase 3; Caspase | 2005 |
Vascular defects and liver damage by the acute inactivation of the VHL gene during mouse embryogenesis.
Topics: Animals; Blood Vessels; Cell Culture Techniques; Cells, Cultured; Culture Media; Embryonic Developme | 2006 |
Downregulation of hepatic cytochrome P-450 isoforms and PPAR-gamma: their role in hepatic injury and proinflammatory responses in a double-hit model of hemorrhage and sepsis.
Topics: Alanine Transaminase; Animals; Aryl Hydrocarbon Hydroxylases; Aspartate Aminotransferases; Cytochrom | 2007 |
Metabolic profiling of serum from gadolinium chloride-treated rats by 1H NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Cr | 2007 |
The role of the anion gap in detecting and managing mixed metabolic acid-base disorders.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Alkalosis; Alkalosis, Respiratory; Anti-Bacter | 1984 |
Value of the glucagon test in screening for hepatic glycogen storage disease.
Topics: Blood Glucose; Fasting; Glucagon; Glycogen Storage Disease; Humans; Lactates; Lactic Acid; Liver Dis | 1982 |
Utilization of L(+) lactate in patients with liver disease.
Topics: Adult; Aged; Ascites; Female; Humans; Lactates; Lactic Acid; Liver Diseases; Male; Metabolic Clearan | 1982 |
Disturbances of lactate metabolism in patients with liver damage due to paracetamol overdose.
Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Viral, Human; Human | 1981 |
Impaired glucose uptake and intact gluconeogenesis in perfused rat liver after carbon tetrachloride injury.
Topics: Animals; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gluconeogenesi | 1995 |
Monitoring of hepatic venous oxygen saturation for predicting acute liver dysfunction after Fontan operations.
Topics: Adolescent; Adult; Alanine Transaminase; Bilirubin; Cardiac Output; Child; Child, Preschool; Fontan | 1994 |
Biotinidase activity in patients with liver disease.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Adult; Aged; Amidohydrolases; Biotin; Biotinidase; Carcinoma, | 1993 |
Protective effect of the calcium channel blocker diltiazem on hepatic function following warm ischemia.
Topics: Animals; Blood Pressure; Diltiazem; Dogs; Female; Femoral Artery; Hot Temperature; Ischemia; Ketone | 1993 |
Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice.
Topics: Anesthesia; Anesthesia Recovery Period; Animals; Brain Chemistry; Carcinogens; Chemical and Drug Ind | 1996 |
The regional production of cytokines and lactate in sepsis-related multiple organ failure.
Topics: Aged; Craniocerebral Trauma; Cytokines; Female; Humans; Interleukin-1; Interleukin-6; Lactic Acid; L | 1997 |
[Prevention of postoperative liver dysfunction by intraoperative administration of PGE1 and dopamine].
Topics: Alprostadil; Anesthesia, Epidural; Dopamine; Drug Therapy, Combination; Hepatectomy; Humans; Intraop | 1996 |
Measurement of lactate levels in serum and bile using proton nuclear magnetic resonance in patients with hepatobiliary diseases: its utility in detection of malignancies.
Topics: Adult; Aged; alpha-Fetoproteins; Bile; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biomarkers; Bi | 1997 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Relationship between blood lactate and early hepatic dysfunction in acute circulatory failure.
Topics: Aged; Bilirubin; Critical Care; Female; Humans; Lactic Acid; Liver Diseases; Male; Medical Records; | 1999 |
Hyperlactatemia syndromes in people with HIV infection.
Topics: Acidosis, Lactic; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; HIV Infections; Homeostas | 2002 |
Clinical aspects of mitochondrial disorders.
Topics: Child, Preschool; Coma; Diabetes Mellitus; DNA, Mitochondrial; Dwarfism; Female; Heart Diseases; Hum | 1992 |
Hepatic dysoxia commences during O2 supply dependence.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Dogs; Hemorrhage; Hydroxybutyrates; Lactates; Lactic | 1992 |
Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation.
Topics: Acute Disease; Ammonia; Animals; Brain; Brain Diseases; Electroencephalography; Glutamates; Glutamic | 1990 |
Paradoxical increase in arterial hydrogen ion concentration in patients with hepatorenal failure given lactate-based fluids.
Topics: Acid-Base Equilibrium; Aged; Bicarbonates; Blood Pressure; Female; Hemofiltration; Humans; Hydrogen- | 1990 |
Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study.
Topics: Acute Disease; Animals; Biomarkers; Brain; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Lactates; | 1989 |
[Significance of lactate analysis in clinical tests].
Topics: Acidosis, Lactic; Diabetes Mellitus; Heart Diseases; Humans; Lactates; Lactic Acid; Liver Diseases; | 1989 |
[Effect of physical training on the aerobic-anaerobic transition in chronic liver diseases].
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Carbon Dioxide; Fatty Acids | 1988 |
Biochemical effects of acute stress on energy metabolism in liver damaged rats.
Topics: Acetyl Coenzyme A; Animals; Chemical and Drug Induced Liver Injury; Cyclic AMP; Cyclic GMP; Energy M | 1987 |
Is blood lactate determination really reliable and useful in critically ill patients with liver disease?
Topics: Humans; Lactates; Lactic Acid; Liver Diseases; Shock | 1988 |
Lactic acidosis in fulminant hepatic failure. Some aspects of pathogenesis and prognosis.
Topics: Acidosis; Blood Pressure; Carbon Dioxide; Female; Humans; Hypoxia; Lactates; Lactic Acid; Liver Dise | 1985 |